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应用三腔起搏器治疗老年顽固性心衰

中国老年学杂志 2003年第8期23卷 506-507页

作者：周晗 SCANU patrice 河南省人民医院心内科河南郑州450003 法国CHU de Caen

目的　观察老年难治性心衰患者应用双心室三腔起搏器治疗的临床效果。方法　选择 1 2例 (其中男 1 1例 ,年龄 71 .2± 9岁 )药物治疗无效的严重心衰患者进行三腔起搏器治疗 (其中 4例安装三腔 ICD)。观察术前、术后 3个月、6个月的 QRS... 详细信息

目的　观察老年难治性心衰患者应用双心室三腔起搏器治疗的临床效果。方法　选择 1 2例 (其中男 1 1例 ,年龄 71 .2± 9岁 )药物治疗无效的严重心衰患者进行三腔起搏器治疗 (其中 4例安装三腔 ICD)。观察术前、术后 3个月、6个月的 QRS波时限、EF值、左室舒张末期内径、二尖瓣返流量、VO2 max以及临床症状的变化情况。结果　随访 3～ 1 2个月 ,全部病例术后 3个月心功能的各项指标与术前相比均有明显改善 (P<0 .0 5) ,且随着随访期的延长有持续改善的趋势。随访期间 1例猝死。结论　双心室同步起搏是治疗难治性心衰的有效的新方法 ,可改善患者血流动力学、心功能和心衰的临床症状。三腔 ICD不仅可进行心衰的双心室同步治疗 ,同时具有良好的抗室性心律失常预防猝死的作用。对具有安装三腔起搏器或三腔 ICD指征的老年心衰患者进行双心室同步治疗安全有效。

关键词：三腔起搏器治疗老年人顽固性心衰双心室同步治疗室性心律失常猝死血液动力学

A Quarter Century of Work to Revolutionize Architecture, Engineering and Construction Enterprise Information Systems

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Journal of Civil Engineering and Architecture 2017年第8期11卷 715-735页

作者： Alain Zarli patrice Poyet CSTB-Centre Scientifique et Technique du Bdtiment BP 209 06904 Sophia Antipolis France Independent researcher https://***/profile/Patrice_Poyet

More than two decades ago, object-oriented representation of AEC （architecture engineering and construction） projects started to offer the promise of seamless communication of semantic data models between computer-based systems used from the design stage to the operation of the facilities. BIM （building information modelling） emerged and appeared as a means to store all relevant data generated during the life-cycle of the facilities. But this upstream view of the built environment, arising from the design and construction stages, extended to the downstream operations where building and industrial facilities appeared more and more as huge dynamic data producers and concentrators while being operated. This created new challenges leading to what is referred to as ISCs （intelligent and smart constructions）. The current state of the art is that final constructions still contain various and increasingly versatile control and service systems, which are hardly standardised, and not interconnected among themselves. Monitoring, maintenance and services are done by specialised companies, each responsible of different systems, which are relying on customised software and techniques to meet specific user needs and are based on monolithic applications that require manual configuration for specific uses, maintenance and support. We demonstrate in this paper that the early promises of integration across the actors and along the life-time of facilities have gone a long way but will only be delivered through enhanced standardisation of computerized models, representations, services and operations still not yet fully accomplished 25 years after work started.

关键词： Architecture engineering and construction building information models semantic interoperability intelligent and smart built environment information systems and sensors for new services.

High-Level Circulating Total Calcium and Low Phosphate as Predictors of Insulin Resistance among Non-Diabetic Taxi-Motorbike Drivers Living and Working in Cotonou, Benin

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Open Journal of Endocrine and Metabolic Diseases 2022年第6期12卷 123-134页

作者： patrice Hodonou Avogbe Ambaliou Sanni Laboratory of Biochemistry and Molecular Biology Department of Biochemistry and Cellular Biology University of Abomey-Calavi Cotonou Republic of Benin

Insulin resistance (IR) is a well-recognized marker of increased cardiovascular diseases (CVDs) and type 2 diabetes (T2D) risk. Therefore, screening for IR predictors would help reduce the likelihood of progression from early stage of IR to T2D or CVDs. However, the knowledge of association between IR and circulating total calcium (CTCa) and phosphate levels among non-diabetic patients in Benin is lacking. We investigated whether CTCa and phosphate levels within the normal ranges are associated with IR risk among taxi-motorbike drivers (TMDs) living and working in Cotonou. We evaluated 134 non-diabetic TMDs (aged 22 - 59 years) based on CTCa, phosphate, glucose, fasting insulin, and IR levels. IR was assessed using the homeostatic model assessment-insulin resistance (HOMA-IR). IR was defined as the 75th percentile of HOMA-IR value. Cardiometabolic factors were analyzed by tertiles of CTCa and phosphate levels (low, middle, and high groups). Logistic regression models evaluated the relationships between IR and CTCa and phosphate levels. Our results showed that participants with high CTCa levels had the highest prevalence of IR, elevated total cholesterol and high-density lipoprotein cholesterol. In a fully adjusted model, the odd ratio (OR) of having IR comparing the highest (>2.50 mmol/L) to the lowest CTCa levels (1.23 mmol/L) and the lowest levels (<1.10 mmol/L) of phosphate was 0.28 (p = 0.037). In conclusion, our study demonstrates that elevated CTCa and low phosphate levels are significant predictors of IR in non-diabetic patients. Continuous monitoring of these markers may help identify earlier individuals at greatest IR risk.

关键词： Blood Glucose Insulin Resistance Circulating Total Calcium Phosphate Taxi-Motorbike Drivers

Elevated White Blood Cell Count Is Associated with an Increased Risk of Insulin Resistance among Non-Diabetic Taxi-Motorbike Drivers Working in Cotonou, Benin

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Journal of Biosciences and Medicines 2022年第8期10卷 68-81页

作者： patrice Hodonou Avogbe Ambaliou Sanni Laboratory of Biochemistry and Molecular Biology Department of Biochemistry and Cellular Biology University of Abomey-Calavi Cotonou Benin

High white blood cell count (WBC) and insulin resistance (IR) are interrelated events that contribute to non-communicable diseases (NCDs), including type-2 diabetes (T2D). However, associations between IR and hematological parameters have never been explored in populations of Benin. The aims of this study were to determine the prevalence of IR and associated hematological parameters in taxi-motorbike drivers (TMDs) working in Cotonou. A total of 133 participants were analyzed in this cross-sectional study. Complete blood count, including WBC and platelet, as well as fasting plasma glucose and insulin, were performed by standard procedures. IR was assessed using the Homeostatic Model Assessment for Insulin Resistance (HOMA-IR). Factors associated with IR, their odds ratios (ORs) and 95% confidence intervals (CIs) were determined by logistic regression analysis. The mean age of the study participants was 39.3 years. The HOMA-IR cut-off (75th percentile) for IR was 5.9. The overall prevalence of IR was 24.1%. IR increased with the increase of exposure duration and WBC levels. Logistic regression analysis revealed that the risk of IR increased significantly with higher total WBC, with adjusted ORs (95% CI) for the second and third tertiles of 3.56 (1.10 - 11.58) and 4.01 (1.21 - 13.31), respectively. Similar patterns of associations were observed in an analysis restricted to non-drinkers, although these estimates lacked statistical significance. BMI > 24.2 kg/m2 was independently associated with an increased risk of IR (OR = 3.82, 95% CI: 1.33 - 11.03, P = 0.013). In conclusion, the prevalence of IR in TMDs was 24.1%. IR was significantly associated with elevated WBC count and BMI. WBC may serve as a biomarker to identify individuals at the greatest IR risk.

关键词： Cotonou Insulin Resistance Taxi-Motorbike Drivers White Blood Cells

Low Plasma Potassium and High Iron Levels Increased the Risk of Dyslipidemia among Non-Diabetic Taxi-Motorbike Drivers Living and Working in Cotonou, Benin

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Open Journal of Endocrine and Metabolic Diseases 2022年第7期12卷 159-175页

作者： patrice Hodonou Avogbe Ambaliou Sanni Laboratory of Biochemistry and Molecular Biology Department of Biochemistry and Cellular Biology University of Abomey-Calavi Cotonou Republic of Benin

Non-traditional cardiovascular risk factors such as iron and potassium may play a role in lipid metabolism. However, information on this association is lacking in populations of Benin. This study evaluated the associations between plasma iron and potassium levels and risk of dyslipidemia among taxi-motorbike drivers (TMDs) in Cotonou. We conducted a cross-sectional study on 134 males TMDs aged ≥20 years old, of whom 39 (29.1%) had dyslipidemia. Plasma biochemistry including measurements of total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C), iron, and potassium were performed. Dyslipidemia was defined as any or combinations of the following: TC > 5.2 mmol/L, LDL-C > 3.4 mmol/L, TG > 1.7 mmol/L, and HDL-C 18.8 μmol/L) to the 1st tertile of plasma iron (nd tertile (4.4 - 4.8 μmol/L) to the 1st tertile (nd and 3rd tertiles to the 1st tertile of plasma potassium were 0.19 (0.04 - 0.87, p = 0.032) and 0.14 (0.02 - 0.93, p = 0.043). In conclusion, our study shows that higher plasma iron and low potassium levels are significant predictors of dyslipidemia in TMDs. As such, the findings have public health implications for predicting and preventing dyslipidemia and associated

关键词： Cotonou Dyslipidemia Iron Potassium Taxi-Motorbike Drivers

Higher Plasma Potassium Level Reduces 10-Year Cardiovascular Disease Risk Predicted by the Framingham Risk Score among Taxi-Motorbike Drivers Residing and Working in Cotonou, Benin

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Journal of Biosciences and Medicines 2023年第4期11卷 417-430页

作者： patrice Hodonou Avogbe Ambaliou Sanni Laboratory of Biochemistry and Molecular Biology Department of Biochemistry and Cellular Biology University of Abomey-Calavi Cotonou Republic of Benin

Hypertension, obesity, smoking, dyslipidemia, and type 2 diabetes (T2D) are the major risk factors for developing cardiovascular diseases (CVD). Recent studies revealed that taxi-motorbike drivers (TMDs) in Cotonou had higher rates of CVD risk factors, but their impacts on cardiovascular events have rarely been studied. The Framingham risk score (FRS) is an algorithm that considers CVD risk factors and estimates the risk of developing CVD in the next 10 years. Our objectives were to assess the 10-year CVD risk predicted by the FRS, and to examine the relationships of 10-year CVD risk with plasma iron and potassium levels among TMDs. We included 134 TMDs (22 - 59 years old) who had no prior diagnosis of CVD or T2D, and not taking medications affecting iron and potassium homeostasis. Conventional cardiovascular risk factors were used to calculate the 10-year CVD risk, which was categorized as low (20%). FRS > 2%, which corresponded to the 75th percentile of FRS distribution in our study population, was used as a cut-off value to classify participants into two groups. Plasma iron and potassium levels were segregated into tertiles and their associations with 10-year CVD risk were quantified by multivariate-adjusted logistic regression to calculate the odd ratios (ORs) to being above the 75th percentile of 10-year CVD risk with the corresponding 95% confidence intervals (CIs). We found that 62.0% of participants had at least one of cardiovascular risk factors. Approximately 97.8% of TMDs had 10-year CVD risk 4.8 mmol/L led to an 83% risk reduction of having 10-year CVD risk > 2% (OR = 0.17, 95% CI: 0.04 - 0.82, P = 0.027). In conclusion, our findings showed that high plasma potassium levels associate with reduced 10-year CVD risk among TMDs. Interventions focused on monitoring of plasma potassium, particularly in those with existing cardiovascular risk factors, may help prevent CVD.

关键词： Cardiovascular Diseases 10-Year CVD Risk Cotonou Framingham Risk Score Plasma Potassium Taxi-Motorbike Drivers

Morphological Diversity of Corn’s (<i>Zea mays</i>L.) Local Cultivar and Improved Varieties in Central and North of Benin

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American Journal of Plant Sciences 2015年第18期6卷 2867-2877页

作者： Hafiz A. Salami Adolphe Adjanohoun Wilfrid Padonou Abdoul-Madjidou Yacoubou djima Aly Chabi Yallou Haziz Sina Lamine Baba-Moussa Laboratoire de Biologie et de Typage Moléculaire en Microbiologie Département de Biochimie et de Biologie Cellulaire Faculté des Sciences et Techniques Université d’Abomey-Calavi Cotonou Bénin Centre de Recherches Agricoles Sud Institut National des Recherches Agricoles du Bénin (INRAB) Attogon Benin Programme Technologie Agricole et Alimentaire (PTAA) Institut National des Recherches Agricoles du Bénin (INRAB) Porto-Novo Benin Centre de Recherches Agricoles Nord Institut National des Recherches Agricoles du Bénin (INRAB) N’dali Benin

The better knowledge of a plant genetic biodiversity is based on a prior study of its agro-morphological characteristics. The objective of this study was to investigate the morphological diversity of maize accessions and its structure on the basis of 14 variables. For the experimentation, 43 and 98 maize accessions were planted in three replicates respectively in central and northern Benin following an incomplete randomized block. The mixed model analysis of two factors variance revealed a significant difference for all accessions considering each agro-morphological characteristic evaluated except the germination day of two areas seed accessions. The numerical classification grouped the accessions into four groups in each zone. The stepwise discriminant analysis showed that early characters related to plant height and ear insertion were the variables that discriminated accessions in both zones. Maturity and recovery ears, sensitivity to streak and the germination days are the variables that discriminate accessions of the two areas. These results provide a database for the creation of improved maize varieties that meet the needs of

关键词： Accessions Characterization Agro-Morphological Zea mays L. Benin

由粉末冶金Fe(Cr,Mo)钢制备的同步器齿毂的力学性能

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粉末冶金技术 2013年第4期31卷 309-313页

作者： Lorenz S Sigl patrice Delarbre Sinterstahl GmbH Ftissen D-87629德国

试验测定零件本身的强度性能是困难的,因此通常不采用此类数据。本文介绍了一种用于直接测定零件本身强度性能的方法,即用水射流切割零件,随后进行磨加工制备小型矩形试棒(约40mm×5mm×5mm)测定数据。采用典型粉末冶金零件——粉末冶... 详细信息

试验测定零件本身的强度性能是困难的,因此通常不采用此类数据。本文介绍了一种用于直接测定零件本身强度性能的方法,即用水射流切割零件,随后进行磨加工制备小型矩形试棒(约40mm×5mm×5mm)测定数据。采用典型粉末冶金零件——粉末冶金高合金化Fe(Cr,Mo)钢同步器齿毂制备的小型试棒测定抗拉强度、冲击强度及3点弯曲横向断裂强度,并和常规拉伸试样(DIN EN ISO 2740)的强度与冲击性能进行了对比。结果表明,由同步器齿毂与常规试样测定的数据都在试验误差范围之内,完全一致。为了证实对比的有效性,还用全面的化学与显微组织分析证明了2种试样的相似性。最后,建立了小型拉伸试棒的横向断裂强度与抗拉强度之间的相关性。

关键词：力学性能硬度拉伸性能横向断裂强度

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无零级衍射干扰的彩色数字全息研究

物理学报 2011年第3期60卷 256-261页

作者：李俊昌樊则宾 Tankam patrice 宋庆和 Picart Pascal 昆明理工大学理学院 LAUM CNRS Université du Maine Av.O.Messiaen 3. ENSIM-cole Nationale Supérieure d’Ingénieurs du Mans rue Aristote

彩色数字全息研究中,用球面波为重建波及角谱衍射公式进行波前重建是一种有效的方法.然而,重建图像上通常伴有强烈的零级衍射干扰.本文通过理论分析,对波前重建过程作了重要改进.用改进后的方法进行彩色数字全息的实验研究表明,重建彩... 详细信息

彩色数字全息研究中,用球面波为重建波及角谱衍射公式进行波前重建是一种有效的方法.然而,重建图像上通常伴有强烈的零级衍射干扰.本文通过理论分析,对波前重建过程作了重要改进.用改进后的方法进行彩色数字全息的实验研究表明,重建彩色图像的质量获得显著改善.

关键词：彩色数字全息波前重建零级衍射干扰