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Protein profile of leprosy patients with plantar ulcers from the Eastern Amazon region

Journal of Water Resource and Protection 2015年第13期 1029-1037页

作者： Marcelo Rocha dos Santos Breno Rosa Neves Bismarc Lopes da silva Sérgio Luiz rodrigues Donato

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Infectious Diseases of Poverty 2017年第1期6卷 947-954页

作者： Marineia Porto de Oliveira Jorge rodrigues de Sousa Rafael silva de Araujo Tinara Leila de Sousa Aarao Juarez Antonio Simoes Quaresma Nucleo de Medicina Tropical Universidade Federal do ParaAv.Generalissimo Deodoro 92UmarizalBelemPara 66055240Brazil Centro de Ciencias Biologicas e da Saude Universidade do Estado do ParaBelemParaBrazil

Background:Studies investigating the nutritional status of patients with leprosy and plantar ulcers are ***,the objective of this study was to describe the protein profile of leprosy patients with plantar ulcers from the Eastern Amazon ***:A case record form was created for 75 patients with leprosy(31 with plantar ulcers and 44 without plantar ulcers)with the following data:sociodemographic characteristics,clinical form of leprosy,presence or absence of plantar ulcers,and nutritional assessment using anthropometry consisting of the measurement of body mass index,arm circumference,arm muscle circumference,and triceps *** of blood albumin,transferrin,and C-reactive protein(CRP)were also *** regarding protein intake were obtained using a Food Frequency ***:Plantar ulcers occurred more frequently in male patients(67.7%),patients aged 40-49 years(mean±SD:47.3±8.0 years),and patients receiving 300 or 600 USD(71.0%).The mean weight and height of patients were 71.6±11.4 kg and 1.62±0.1 m,*** levels of CRP were detected in 51.6%of leprosy patients with plantar ulcers and only 9.1%of patients without plantar ulcers(P<0.001).Nutritional depletion of transferrin was observed in 14.3%of patients with paucibacillary leprosy and 44.3%of patients with multibacillary leprosy(P=0.0447).Most patients had normal levels of serum albumin(74.2%with plantar ulcers and 77.3%without plantar ulcers).Conclusions:Most leprosy patients with plantar ulcers have normal levels of serum albumin and transferrin and high CRP levels,which indicates the presence of an inflammatory *** findings suggest the need to monitor patients with leprosy to prevent the occurrence of plantar ulcers and to provide adequate treatment for patients with existing plantar ulcers.

关键词： Leprosy Plantar ulcer Nutritional status Anthropometric assessment Albumin Transferrin C-reactive protein

An Updated Mini Review of Acute and Chronic Responses to Exercise Training-induced Irisin in Browning of White Fat

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Journal of Endocrinology Research 2019年第1期1卷 1-7页

作者： Sílvia Rocha-rodrigues Bruno silva Polytechnic Institute of Viana do Castelo School of Sport and LeisureMelgacoPortugal Laboratory of Metabolism and Exercise Research Centre in Physical ActivityHealth and Leisure(CIAFEL)Faculty of Sport SciencesUniversity of PortoPortugal Research Center in Sports Sciences Health and Human Development(CIDESD)Vila RealPortugal

Nowadays,is well established that the benefits induced by exercise training(ET)affects not only skeletal muscle,but also other non-contractile organs over *** potential mechanism underlying this crosstalk is the synthesis and secretion of several biological active factors,such as irisin,by muscle contractile *** hormone has been described to be able to induce a brown adipocyte-like phenotype in white adipose(WAT),increase whole-body metabolic rate,and therefore prevent and/or treat obesity-related metabolic ***,the modulatory impact of ET on WAT may also occur through skeletal muscle-adipose organ *** this review,we summarize the acute and chronic adaptations to ET-induced irisin synthesis and secretion on the development of browning of white fat and,thus,providing an overview of the potential preventive and therapeutic role of ET on the obesity-related underlying pathways.

关键词： Hormones Exercise PGC-1α UCP1

<i>In Vitro</i>Priming of Sugarcane Varieties (RB966928 and RB867515)

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American Journal of Plant Sciences 2018年第4期9卷 763-774页

作者： Rafaela Pereira Duarte Rodrigo Kelson silva Rezende Fernanda Pinto Maílson Vieira Jesus Izaias rodrigues da silva Junior Ana Maria Scoton Faculty of Agrarian Sciences Federal University of Grande Dourados Dourados Brazil

Sugarcane, as a glycophyte, shows sensitivity to saline soils at various stages of its growth. The aim of this study was to evaluate the in vitro priming response in two sugarcane varieties (RB966928 and RB867515). Micropropagated plants, from meristems, received priming treatments by adding the salts (NaCl and KCl) in different concentrations (0.0;12.5;25.0 and 50.0 mM), in the MS medium. Subsequently, the plants were cultivated in rooting medium without addition of salts, acclimatized and submitted to gradient ex vitro saline stress with 20 → 40 and 60 mM, of each salt, for 30 days. The analyzed variables were dry matter of shoot and root, number of tillers and estimation of chlorophyll content. The experiment was carried out in a 2 × 2 × 4 factorial arrangement, in a completely randomized experimental design. Twenty replicates were used throughout the experiment. data were submitted to analysis of variance and regression and the means were compared by Tukey’s test, at a 5% probability level. The priming treatments presented a significant effect, with triple interaction, in the chlorophyll index. In the treatment with NaCl, the variety RB966928 showed an increase in the chlorophyll index with the increase of treatment levels, up to an optimal limit of 31.47 mM. On the other hand, the variety RB867515 showed decreasing in chlorophyll index. In contrast, in KCl treatment, the variety RB867515 presented the increase at the chlorophyll index with the maximum point of 25 mM. For the variables, shoot dry matter (SDM) and root dry matter (RDM) there was a significant difference (p 0.05 and p 0.01, respectively) only between the varieties. The variety RB966928 presented higher SDM and RDM in relation to the variety RB867515. Studies are recommended with increasing the duration of the priming treatments and more detailed study of the culture throughout its productive cycle.

关键词： Salinity Stress Micropropagation Saccharum officinarum L.

Phytochemical bioprospecting, antioxidant, antimicrobial and cytotoxicity activities of saline extract from Tithonia diversifolia(Hemsl) *** leaves

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Asian Pacific Journal of Tropical Biomedicine 2018年第5期8卷 245-253页

作者： Bruno Rafael Barboza Bárbara Rafaela da silva Barros Bárbara de Azevedo Ramos Maiara Celine de Moura Thiago Henrique Napoleao Maria Tereza dos Santos Correia Luana Cassandra Breitenbach Barroso Coelho Iranildo José da Cruz Filho Ana Maria Souto Maior Túlio Diego da silva Leylianne de Cássia rodrigues Nerys Edson Renan Barros de Santana Cláudia Sampaio de Andrade Lima Virgínia Maria Barros de Lorena Cristiane Moutinho Lagos de Melo Department of Antibiotics Biosciences Centre Federal University of Pernambuco Department of Biochemistry Biosciences Centre Federal University of Pernambuco Center for Strategic Techmologies of the Northeast Department of Biophysics Biosciences Centre Federal University of Pernambuco Aggeu Magalhaes Institute IAM/FIOCRUZ

Objective:To evaluate antimicrobial and antioxidant properties of saline extract from Tithonia diversifolia leaves by phytochemical bioprospecting,and investigate its safety against animal ***:The saline extract was prepared,with NaCl(0.15 M),by constant stirring of the dried and pulverized leaves,followed by volume reduction by *** extract was phytochemical characterized using ultra-performance liquid chromatography,and total phenol and flavonoid analysis also was *** antioxidant capacity was determined through DPPH*radical,the antimicrobial property was evaluated against standard bacteria and fungi,and the viability assays were performed against mice ***:Fifteen compounds were identified belonging to two main classes terpenoids and *** extract showed 22.185 mg GAE/g of total phenolic compounds and 3.220 mg QE/g of ***,extract showed higher antioxidant ability similar to butylated hydroxytoluene a standard molecule[(3.042±0.019)mg AAE/g and(4.12±0.10)mg AAE/g to saline extract and butylated hydroxytoluene,respectively].The antimicrobial assays demonstrated that the extract had a significant antifungal potential against Candida species and could be used with safety against mice splenocytes,in concentrations lower than 50μg/mL,promoting higher proliferation in these ***:Saline extract from Tithonia diversifolia leaves presents potential antioxidant,antifungal properties and induces immunostimulation in mice splenocytes.

关键词： Tithonia diversifolia Extract Antioxidant Antifungal properties Immunostimulation

Influence of the rainfall in the content of nutrients in litter in agroforestry systems managed with burning and without burning in Amazon

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Agricultural Sciences 2013年第11期4卷 26-36页

作者： Rosecélia Moreira da silva Castro Maria De Lourdes Pinheiro Ruivo Jorge Luiz Piccinin Eraldo Ferreira rodrigues Brazilian Company of Agricultural Research Statistical Department Belém Brasil Emilio Goeldi Pará Museum Coordination of Earth Sciences and Ecology Belém Brasil Federal University of Rural Amazonia Institute Sciences Agricultural Belém Brasil

This study evaluated the nutrient content of the litter, testing different treatments with burning and no burning, of the vegetation, to identify which one provides better efficiency in operation and production of nutrients in different seasonal conditions. The study area is located on the property of the family farmer, initially selected by a diagnosis socioeconomic, community Benjamin Constant, in northeastern Para. Litter was collected during two periods: dry season (November) and rainy (March) in 2009. For the collection of litter samples, we used collectors measuring (0.25 × 0.25 m2), which were placed directly on the soil surface. The collected material was stored in paper bags and taken to the laboratory for Chemical Analysis of the Brazilian Agricultural Research Corporation (EMBRAPA), which was determined by analyses of macronutrients (N, P, K, Ca, Mg, Na) and micronutrients (Fe, Cu, Mn, Zn). The highest concentrations of macronutrients were found in N for agroforestry systems with and without burning in two seasons (wet and dry). All macronutrients showed influence of seasonality, which was verified by the wide variation in nutritional behavior. The decreasing concentration of nutrients was presented N > Ca > Mg > Na > K > P in agroforestry system with burning, with maximum values of all nutrients in the rainy season, and N, P, K, Ca, Na in higher concentrations in agroforestry system without burning, and showed only the Mg peak in agroforestry system with burning. The behavior of the concentration of nutrients was opposite to that observed one, for all elements analyzed showed a reduction in the concentrations of nutrients in the dry season. The decreasing concentration of nutrients was presented Fe > Mn > Zn > Cu.

关键词： Forest Management Ecosystem Seasonality Litterfall

Effect of Kinesio Taping on Hand Function in Hemiparetic Patients

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World Journal of Neuroscience 2018年第2期8卷 293-302页

作者： Jonathan Galvao Tenorio Cavalcante Maria do Desterro Costae silva Jessiane Tenorio da Fonseca silva Clarissa Cotrim dos Anjos Renata Sampaio rodrigues Soutinho School of Physical Therapy Alagoas State University of Health Sciences(UNCISAL)MaceioBrazil Alagoas State University of Health Sciences(UNCISAL) MaceioBrazil CESMAC University MaceioBrazil

Introduction: Cerebrovascular accident (CVA) is the second most frequent cause of death in the world. Nevertheless, most victims do survive and need treatment, and hand function is one that has to be dealt with in the rehabilitation process. Kinesio®?Taping (KT) is a bandaging method that can be applied along the muscle fibers to provide stimulation. Studies have shown its efficacy in providing afferent stimuli to weakened muscles, thus eliciting contraction with greater recruiting of motor units and inducing neuroplasticity. Benefits to the paresthesia hand have not been reported. Objective: Investigate the effects of KT on hand function in hemiparetic patients. Material and Methods: An evaluator-blinded, randomized clinical trial involving stroke victims was carried out in a physical therapy outpatient clinic. One group underwent KT intervention and the other was a control group. The Modified Ashworth Scale (MAS) and the Box and Block Test (BBT) were used as assessment tools. A data entry form was used in the Epi-info 7 software and descriptive statistics was thus calculated. The software BioStat 5.0 was employed when doing statistical tests. Associations were regarded as statistically significant when p 0.05. Results: Eight individuals were randomly assigned to two groups. All those who had received treatment with KT had spasticity improved by one point, but there was no significant improvement in BBT. Conclusion: KT was effective when it came to improving spasticity and it may be an option in rehab, but it had no effect on gross manual dexterity. Nevertheless, it can be of help as part of a functional training program.

关键词： Stroke Rehabilitation Physical Therapy Kinesio^(█) Taping Hands

Comparison of morphological and functional outcomes of mouse sciatic nerve repair with three biodegradable polymer conduits containing poly (lactic acid)

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Neural Regeneration Research 2018年第10期13卷 1811-1819页

作者： Fernanda Marques Pestana Rui C.C.Domingues Júlia Teixeira Oliveira daniela F.P.A.Durco Camila Oliveira Goulart Henrique Rocha Mendonca Anne Caroline rodrigues dos Santos Natália Tavares de Campos Beatriz Theodoro da silva Cristina Cardoso Pereira Cristiano Piacsek Borges Ana Maria Blanco Martinez Pós Graduacao em Ciências Morfológicas Instituto de Ciências Biomédicas-UFRJRio de Janeiro RJ Brazil Anatomia Patológica-Faculdade de Medicina-HUCFF-UFRJ Rio de Janeiro RJ Brazil Laboratório de Neurodegeneracao e Reparo-Faculdade de Medicina-HUCFF-UFRJ Rio de Janeiro RJ Brazil Programa de Eng. Química COPPE-UFRJRio de Janeiro Brazil Polo Universitário de Macaé Laboratório Integrado de Produtos Bioativos e BiociênciasMacaê UFRJ Brazil

Poly（lactic acid）（PLA）-containing nerve guidance conduits（NGCs） are currently being investigated for nerve repair as an alternative to autograft, which leads to permanent functional impairment in the territory innervated by the removed nerve. Combination of polymers modifies the physical properties of the conduits, altering their nerve-guidance properties. Conduits made from PLA-only or combined with other polymers have been used successfully for nerve repair, but their efficiency has not been compared. We compared the morphological and functional outcomes of peripheral nerve repair by using NGCs made of poly（lactic acid） and combined or not with polycaprolactone（PLA/PCL） or polyvinylpyrrolidone（PLA/PVP）. To assess the functional recovery, we employed a mechanical hyperalgesia analysis, sciatic functional index（SFI）, and electroneuromyography. The mechanical hyperalgesia analysis showed that the PLA group improved more rapidly than the PLA/PVP and PLA/PCL groups; similarly, in the electroneuromyography assay, the PLA group exhibited higher amplitude than the PLA/PCL and PLA/PVP groups. However, the SFI improvement rates did not differ among the groups. Morphologically, the PLA group showed more vascularization, while the nerve fiber regeneration did not differ among the groups. In conclusion, the PLA-only conduits were superior to the other NGCs tested for nerve repair.

关键词： sciatic nerve tubulization biodegradable conduit poly(lactic acid) regeneration

Sexual Diversity and Homophobia in Health Care Services: Perceptions of Homosexual and Bisexual Population in the Cross-Cultural Theory

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Open Journal of Nursing 2016年第6期6卷 470-482页

作者： Grayce Alencar Albuquerque Glauberto da silva Quirino Francisco Winter dos Santos Figueiredo Laércio da silva Paiva Luiz Carlos de Abreu Vitor Engrácia Valenti Vânia Barbosa do Nascimento Erika da silva Maciel Fernando rodrigues Peixoto Quaresma Fernando Adami Regional University of Cariri Ceará Brazil School of Medicine of ABC S&atildeo Paulo Brazil Paulista State University Campus of Marilia S&atildeo Paulo Brazil University Center Lutheran of Palmas CEULP-ULBRA Tocantins Brazil

The provision of care by health professionals seems to be related to cultural patterns in which these workers are inserted. The relationship between culture and care becomes a challenge for the provision of health care to homosexual and bisexual population. Thus, this study aimed to identify the perception of Gays, Lesbians, Bisexuals and Transgenders in relation to the care received from health professionals, in the light of Cross-Cultural Theory. This is a qualitative, ethnographic study, conducted with 30 members of sexual minorities in Juazeiro do Norte, Brazil. The data analysis lead to the elaboration of five categories based on of the Theory of Cultural Care Diversity and Universality. The participants emphasized the constant violation of their rights to universal and equitable access to the National Health System, stating that they have suffered from prejudice and exclusion, as result of a heteronormative culture. They highlighted that homophobia and dehumanization of care have a strong relation to sexual orientation. The transvestites are the most prone to humiliation and pejorative attitudes of professionals and such condition is a barrier to accessing services.

关键词： Health Care Health Disparities Discrimination Homophobia Theory

A New Approach to Reducing Mortality from Dengue

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Open Journal of Clinical Diagnostics 2014年第1期4卷 12-16页

作者： Sonia Maria Oliveira de Andrade Cyntia Maria Moreira Herkert Rivaldo Venancio da Cunha Mariana Delfino rodrigues Baldomero Antonio Kato da silva Physiotherapy Program Universidade Federal do Piauí Parnaíba Brazil Post Graduate Program in Infectious and Parasitic Diseases School of Medicine Universidade Federal de Mato Grosso do Sul Campo Grande Brazil

In 2009, based on a multicenter study conducted in Asia and Latin Americaand subsidized by the Dengue Control (DENCO) Research Program, the World Health Organization (WHO) proposed a new classification for dengue cases. The purpose of the present study was to evaluate the applicability of the new classification, relative to its previous version [1]. The evaluation, conducted in Campo Grande county, Mato Grosso do Sul state, Brazil, drew on secondary data from referral healthcare centers that assist high-severity dengue patients. A total of 156 medical records of patients with laboratory diagnosis of dengue were investigated. The records covered two epidemic periods: summer of 2006-2007 and summer of 2009-2010. The results showed that 64.6% of cases classified as dengue fever under the 1997 criteria presented manifestations of severity, warranting their reclassification as dengue with warning signs (49) or severe dengue (15) under the 2009 revised criteria. Bleeding, persistent vomiting, and severe, continuous abdominal pain were the most prevalent warning signs, indicative of risk of progression to severe disease. The revised classification was proved less complex than the current version, facilitating the identification of cases and the clinical management of patients.

关键词： Dengue Disease Classification World Health Organization