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Minimally invasive treatment of pancreatic pseudocysts

World Journal of Gastroenterology 2015年第22期21卷 6850-6860页

作者： Enver Zerem Goran Hauser Svjetlana Loga-Zec Suad Kunosi Predrag Jovanovi dino crnki Department of Gastroenterology University Clinical Center Tuzla Department of Medical Sciences The Academy of Sciences and Arts of Bosnia and Herzegovina Department of Internal Medicine Division of Gastroenterology Clinical Hospital Centre Rijeka Institute of Pharmacology Medical FacultyUniversity of Sarajevo Department of Physics Faculty of Natural Sciences and Mathematics University of Tuzla Faculty of Pharmacology University of Tuzla

A pancreatic pseudocyst(PPC) is typically a complication of acute and chronic pancreatitis, trauma or pancreatic duct obstruction. The diagnosis of PPC can be made if an acute fluid collection persists for 4 to 6 wk and is enveloped by a distinct *** PPCs regress spontaneously and require no treatment, whereas some may persist and progress until complications occur. The decision whether to treat a patient who has a PPC, as well as when and with what treatment modalities, is a difficult one. PPCs can be treated with a variety of methods: percutaneous catheter drainage(PCD), endoscopic transpapillary or transmural drainage, laparoscopic surgery, or open pseudocystoenterostomy. The recent trend in the management of symptomatic PPC has moved toward less invasive approaches such as endoscopic- and image-guided PCD. The endoscopic approach is suitable because most PPCs lie adjacent to the stomach. The major advantage of the endoscopic approach is that it creates a permanent pseudocysto-gastric track with no spillage of pancreatic enzymes. However, given the drainage problems, the monitoring, catheter manipulation and the analysis of cystic content are very difficult or impossible to perform endoscopically, unlike in the PCD approach. Several conditions must be met to achieve the complete obliteration of the cyst *** duct anatomy is an important factor in the prognosis of the treatment outcome, and the recovery of disrupted pancreatic ducts is the main prognostic factor for successful treatment of PPC, regardless of the treatment method used. In this article, we review and evaluate the minimally invasive approaches in the management of PPCs.

关键词： Complications Pseudocyst Treatment Drainage Outcomes

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Feeding Calcium Salts of Linseed Oil on Metabolic Status and Reproductive Traits in Grazing Dairy Cows

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Open Journal of Animal Sciences 2024年第3期14卷 219-233页

作者： Jesica Daniela Iorio Yaliska Moreno González Maria Florencia Olmeda dino Curletto Daniel Edgardo Scandolo Martin Guillermo Maciel Rafael Alejandro Palladino Mauricio Javier Giuliodori Eloy Eduardo Salado School of Agriculture of the University of Buenos Aires (FAUBA) Buenos Aires Argentina Faculty of Agricultural Sciences National University of Lomas de Zamora (UNLZ) Lomas de Zamora Argentina Rafaela Agricultural Experiment Station National Institute of Agricultural Technology (INTA) Rafaela Argentina Faculty of Veterinary Science La Plata National University (FCV) La Plata Argentina

This experiment aimed to evaluate the effect of calcium salts of linseed oil (rich in alpha-linolenic acid (ALA, C18:3n-3) on metabolic and reproductive traits in high-producing dairy cows under grazing. Thirty-six Holstein dairy cows were randomly assigned, in a complete block design, to receive ALA supplementation (0.85 kg∙day−1 of calcium salts of linseed oil) or to remain as untreated control (CON). The concentrate was formulated to offer the same amount of energy across treatments (CON cows received an extra kg of corn to compensate for the higher energy density of ALA treatment). A PMR + Alfalfa pasture was offered to all cows at the same time. A fixed time artiﬁcial insemination (FTAI) at 80 DIM, preceded by a Presynch plus Ovsynch protocol was implemented for the first service and later, on return to estrus, heat detection and artiﬁcial insemination (AI) were performed. Pregnancy diagnosis was checked at 30, 42, 60, and 90 d after AI. Blood and milk samples were taken biweekly. Treatment affected plasma cholesterol concentration (160.36 vs. 186.70 mg∙dl−1, p = 0.03, for ALA and CON, respectively) and on size of corpus luteum (CL, 17.6 vs. 13.7 mm, p = 0.02, for ALA and CON, respectively). Supplementation tended (p = 0.136) to increase conception rate by 200 DIM (81.69% vs. 55.43% in ALA and CON cows, respectively). However, treatment had no effect (p > 0.05) on body weight (BW), body condition score (BCS), and circulating levels of beta-hydroxybutyrate (BHBA), glucose, insulin, growth hormone (GH) and insulin-like growth factor (IGF-I). Our results suggest that supplementation with calcium salts of linseed oil could enhance ovarian function without affecting energy metabolism in early lactation dairy cows.

关键词： α-Linolenic Acid Supplementation Reproduction Grazing Dairy Cows

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Commentary on “An alternative surgical technique for varicoceles: a preliminary experience of the microsurgical spermatic (distal end)-inferior or superficial epigastric vein anastomosis in symptomatic varicoceles associated with perineal pain”

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Asian Journal of Andrology 2023年第4期25卷 537-538页

作者： dino Papes Department of Pediatric Surgery University Hospital Centre ZagrebZagreb 10000Croatia

Dear Editor,I have read with care the article of Wan et al.1 on microsurgical bypass for varicocele *** several issues would,in my opinion,improve the quality of future research of this interesting technique,similar to the one we reported for varicocele treatment in children and adolescents.2 The term perineal pain is usually used for discomfort associated with chronic *** is not clear whether the patients in this study had testicular pain due to varicocele or the pain was localized in the perineum,which would,in turn,suggest the possibility of another etiology.

关键词： pain varicocele surgical

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Biomass gasification technology:The state of the art overview

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Journal of Energy Chemistry 2016年第1期25卷 10-25页

作者： Antonio Molino Simeone Chianese dino Musmarra ENEA National Agency for New TechnologiesEnergy and Sustainable Economic Development Department of Civil and Building Engineering Design and Environment(DICDEA)Second University of Naples(SUN)-via Roma

In the last decades the interest in the biomass gasification process has increased due to the growing attention to the use of sustainable energy. Biomass is a renewable energy source and represents a valid alternative to fossil fuels. Gasification is the thermochemical conversion of an organic material into a valuable gaseous product, called syngas, and a solid product, called char. The biomass gasification represents an efficient process for the production of power and heat and the production of hydrogen and second-generation *** paper deals with the state of the art biomass gasification technologies, evaluating advantages and disadvantages, the potential use of the syngas and the application of the biomass gasification. Syngas cleaning though fundamental to evaluate any gasification technology is not included in this paper since; in the authors＇ opinion, a dedicated review is necessary.

关键词： Gasification Biomass Syngas Gasification technology Biofuel Power and heat generation

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Acute and long-term changes in blood flow after ischemic stroke:challenges and opportunities

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Neural Regeneration Research 2023年第4期18卷 799-800页

作者： dino Premilovac Brad A.Sutherland Tasmanian School of Medicine College of Health and MedicineUniversity of TasmaniaHobartTASAustralia

The brain has a high metabolic rate and consumes approximately 20% of the total energy in the body at any given time. Although it requires a large amount of energy to function, the brain cannot store significant amounts of energy making it exquisitely dependent on constant nutrient supply via blood flow. When blood flow to the brain is impaired, such as during stroke, there are rapid and severe consequences for the neurons that depend on this constant energy supply.

关键词： impaired flow Acute

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Silver impregnated carbon for adsorption and desorption of elemental mercury vapors

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Journal of Environmental Sciences 2011年第9期23卷 1578-1583页

作者： Despina Karatza Marina Prisciandaro Amedeo Lancia dino Musmarra Dipartimento di Ingegneria Chimica Universitàdi Napoli "Federico II" Dipartimento di Chimica Ingegneria Chimica e MaterialiUniversitàde L’Aquila Centro Interdipartimentale di Ricerca in Ingegneria Ambientale Dipartimento di Ingegneria CivileSeconda Universitàdegli Studi di NapoliReal Casa dell’AnnunziataVia Roma 2981031 Aversa (CE)Italy

The Hg 0 vapor adsorption experimental results on a novel sorbent obtained by impregnating a commercially available activated carbon （Darco G60 from BDH） with silver nitrate were *** study was performed by using a fundamental approach,in an apparatus at laboratory scale in which a synthetic flue gas,formed by Hg 0 vapors in a nitrogen gas stream,at a given temperature and mercury concentration,was flowed through a fixed bed of adsorbent *** curves and adsorption isotherms were obtained for bed temperatures of 90,120 and 150°C and for Hg 0 concentrations in the gas varying in the range of 0.8–5.0 mg/m 3 .The experimental gas-solid equilibrium data were used to evaluate the Langmuir parameters and the heat of *** experimental results showed that silver impregnated carbon was very effective to capture elemental mercury and the amount of mercury adsorbed by the carbon decreased as the bed temperature *** addition,to evaluate the possibility of adsorbent recovery,desorption was also *** runs showed that both the adsorbing material and the mercury could be easily recovered,since at the end of desorption the residue on solid was almost *** material balance on mercury and the constitutive equations of the adsorption phenomenon were integrated,leading to the evaluation of only one kinetic parameter which fits well both the experimentally determined breakthrough and desorption curves.

关键词： mercury carbon MSW incinerators adsorption desorption silver nitrate

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A perspective on Gaussian processes for Earth observation

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National Science Review 2019年第4期6卷 616-618页

作者： Gustau Camps-Valls dino Sejdinovic Jakob Runge Markus Reichstein Image Processing Laboratory University of Valencia Department of Statistics University of Oxford German Aerospace Center Institute of Data Science Max Planck Institute for Biogeochemistry

INTRODUCTION Earth observation (EO) by airborne and satellite remote sensing and in situ observations plays a fundamental role in monitoring our planet. In the last decade, machine learning has attained outstanding results in the estimation of bio-geo-physical variables from the acquired images at local and global scales in a time-resolved manner. Gaussian processes (GPs)[1], as flexible

关键词： Earth Gaussian A perspective on Gaussian processes for Earth observation

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Extreme gastric dilation caused by chronic lead poisoning: A case report

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World Journal of Gastroenterology 2008年第16期14卷 2599-2601页

作者： Vesna Begovic Darko Nozic Srdjan Kupresanin dino Tarabar Clinic of Infectious and Tropical Diseases Military Medical Academy Crnotravska 17 Institute of Radiology Military Medical Academy Crnotravska 17 Clinic of Gastroenterology Military Medical Academy Crnotravska 17

Lead is a toxic metal that affects many organ systems and functions in humans. In the majority of adults, chronic lead poisoning comes from exposures to work places and can occur in numerous work settings, such as manufacturing, lead smelting and refinement, or due to use of batteries, pigments, solder, ammunitions, paint, car radiators, cable and wires, certain cosmetics. In some countries, lead is added to petrol. We present a rare case of gastric dilation caused by long-term petrol ingestion. A 16-year-old young man was admitted to our hospital due to a 6-mo history of exhaustion, dizziness, nausea, abdominal cramps and constipation. X-ray examination revealed dilated stomach descending into the pelvis and small bowel distension. After a long clinical observation, we found that the reason for the chronic lead poisoning of the patient was due to a 3-year history of petrol ingestion. The patient spontaneously recovered and stomach returned to its normal position and size. Lead poisoning should be taken into consideration in all unexplained cases of gastric dilation.

关键词： Lead Petrol Stomach Poisoning Gastricdilation

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Envita’s Precision Cancer Care: 35-Fold Improvement in Response Rates

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Journal of Cancer Therapy 2024年第4期15卷 99-120页

作者： Sheba Goklany John C. Oertle III Ronald Matthias Jr. Daniel Warren David Medina Rory Sears Robert Zieve Kendra Quart Christopher Aussems Jon Moma Shannon Miller Zach Poteet Conner Coffin Courtney Middleton Erika Ware Phylicia Zarnosky Julie Nowak Winlove Suasin Daniel Conway Chad Burk Ruth Tan-Lim dino Prato Envita Medical Centers Scottsdale AZ USA

New clinical approaches are imperative beyond the widely adopted National Comprehensive Cancer Network (NCCN) guidelines, utilized by prominent cancer institutions. Cancer is the leading cause of death among individuals younger than 85 years within the United States. Despite significant technological advances, including the expenditure of hundreds of billions, treatment outcomes and overall survival have not notably improved for most types of advanced cancer over the last several decades. Over the past 24 years, Envita Medical Centers has pioneered a unique form of personalized treatment approach for late-stage and refractory cancer patients, introducing groundbreaking innovations in the field. Our integrated algorithm utilizes advanced genomics, transcriptomics, and highly tailored immunotherapy, resulting in remarkable outcome improvements. This study presents Envita’s innovative personalized treatment algorithms and examines the response outcomes of 199 late-stage cancer patients treated at Envita Medical Centers over a two-year period. Compared to standard of care and palliative chemotherapy, Envita’s treatment demonstrated a remarkable 35-fold improvement in overall response rates (Figure 1). Moreover, 88% of the patients, the majority presenting with Stage 3 or 4 cancer, experienced a 43-fold improvement in quality of life with minimal side effects, as compared to standard of care chemotherapy and palliative care. This revolutionary success is attributed to Envita’s personalized therapeutic algorithms, which incorporate customized immunotherapy. Envita’s precision care approach has also achieved a 100% better response rate compared to over 65 global chemotherapy clinical trials with more than 2700 patients. The results from this study suggest that a wider utilization of Envita’s personalized approach can significantly benefit patients with late-stage and refractory cancer.

关键词： Envita Medical Centers Late-stage Cancer Overall Response Rate Quality of Life Circulating Tumor Cells (CTCs) Mutant Allele Frequency (MAF) Precision Care

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The acceleration of a high-charge electron bunch to 10 GeV in a 10-cm nanoparticle-assisted wakefield accelerator

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Matter and Radiation at Extremes 2024年第1期9卷 15-24页

作者： Constantin Aniculaesei Thanh Ha Samuel Yoffe Lance Labun Stephen Milton Edward McCary Michael M.Spinks Hernan J.Quevedo Ou Z.Labun Ritwik Sain Andrea Hannasch Rafal Zgadzaj Isabella Pagano Jose A.Franco-Altamirano Martin L.Ringuette Erhart Gaul Scott V.Luedtke Ganesh Tiwari Bernhard Ersfeld Enrico Brunetti Hartmut Ruhl Todd Ditmire Sandra Bruce Michael E.Donovan Michael C.Downer dino A.Jaroszynski Bjorn Manuel Hegelich University of Texas at Austin AustinTexas 78712USA SUPA Department of Physics University of StrathclydeGlasgowScotland G4 ONGUnited Kingdom Tau Systems Inc.AustinTexas 78701USA Lawrence Livermore National Laboratory LivermoreCalifornia 94550USA Los Alamos National Laboratory Los AlamosNew Mexico 87545USA Brookhaven National Laboratory UptonNew York 11973USA Ludwig-Maximilians-Universität MunichGermany

An intense laser pulse focused onto a plasma can excite nonlinear plasma *** appropriate conditions,electrons from the background plasma are trapped in the plasma wave and accelerated to ultra-relativistic *** scheme is called a laser wakefield *** this work,we present results from a laser wakefield acceleration experiment using a petawatt-class laser to excite the wakefields as well as nanoparticles to assist the injection of electrons into the accelerating phase of the *** find that a 10-cm-long,nanoparticle-assisted laser wakefield accelerator can generate 340 pC,10±1.86 GeV electron bunches with a 3.4 GeV rms convolved energy spread and a 0.9 mrad rms *** can also produce bunches with lower energies in the 4–6 GeV range.

关键词： acceleration nanoparticle charge

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