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Microalgae:A potential alternative to health supplementation for humans

Food Science and Human Wellness 2019年第1期8卷 16-24页

作者： Apurav Krishna Koyande Kit Wayne Chew Krishnamoorthy Rambabu Yang Tao dinh-toi chu Pau-Loke Show Department of Chemical Engineering Faculty of EngineeringUniversity of Nottingham Malaysia43500Selangor Darul EhsanMalaysia Department of Chemical Engineering School of Civil and Chemical EngineeringVIT UniversityVellore632014Tamil NaduIndia College of Food Science and Technology Nanjing Agricultural University1 Weigang RoadNanjingJiangsu210095China Institute for Research and Development Duy Tan UniversityK7/25 QuangTrungDanangViet Nam Faculty of Biology Hanoi National University of Education136 XuanThuyCauGiayHanoiViet Nam

Microalgae has been consumed in human diet for thousands of *** is an under-exploited crop for production of dietary *** cultivation does not compete with land and resources required for traditional crops and has a superior yield compared to terrestrial *** high protein content has exhibited a huge potential to meet the dietary requirements of growing *** from being a source of protein,presence of various bio-active components in microalgae provide an added health *** review describes various microalgal sources of proteins and other bio-active *** of the heavily studied group of bio-active components are pigments due to their anticarcenogenic,antioxidative and antihypertensive *** to various plant and floral species,microalgae contain higher amounts of *** derived proteins have complete Essential Amino Acids(EAA)profiles and their protein content is higher than conventional sources such as meat,poultry and dairy ***,microalgal based functional foods have not flooded the *** lack of awareness coupled with scarce incentives for producers result in under-exploitation of microalgal *** of microalgal derived components as dietary and nutraceutical supplements is discussed comprehensively.

关键词： Health Human Microalgae Protein Supplement

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Treadmill exercise in combination with acousto-optic and olfactory stimulation improves cognitive function in APP/PS1 mice through the brain-derived neurotrophic factor-and Cygb-associated signaling pathways

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Neural Regeneration Research 2025年第9期20卷 2706-2726页

作者： Biao Xiao Chaoyang chu Zhicheng Lin Tianyuan Fang Yuyu Zhou chuxia Zhang Jianghui Shan Shiyu Chen Liping Li Department of Physiology and Pharmacology Health Science CenterNingbo UniversityNingboZhejiang ProvinceChina Ningbo Key Laboratory of Behavioral Neuroscience Health Science CenterNingbo UniversityNingboZhejiang ProvinceChina Key Laboratory of Addiction Research of Zhejiang Province NingboZhejiang ProvinceChina

A reduction in adult neurogenesis is associated with behavioral abnormalities in patients with Alzheimer's ***,enhancing adult neurogenesis represents a promising therapeutic approach for mitigating disease symptoms and ***,nonpharmacological interventions aimed at inducing adult neurogenesis are currently *** individual non-pharmacological interventions,such as aerobic exercise,acousto-optic stimulation,and olfactory stimulation,have shown limited capacity to improve neurogenesis and cognitive function in patients with Alzheimer's disease,the therapeutic effect of a strategy that combines these interventions has not been fully *** this study,we observed an age-dependent decrease in adult neurogenesis and a concurrent increase in amyloid-beta accumulation in the hippocampus of amyloid precursor protein/presenilin 1 mice aged 2-8 *** deposition became evident at 4 months,while neurogenesis declined by 6 months,further deteriorating as the disease ***,following a 4-week multifactor stimulation protocol,which encompassed treadmill running(46 min/d,10 m/min,6 days per week),40 Hz acousto-optic stimulation(1 hour/day,6 days/week),and olfactory stimulation(1 hour/day,6 days/week),we found a significant increase in the number of newborn cells(5'-bromo-2'-deoxyuridine-positive cells),immature neurons(doublecortin-positive cells),newborn immature neurons(5'-bromo-2'-deoxyuridine-positive/doublecortin-positive cells),and newborn astrocytes(5'-bromo-2'-deoxyuridine-positive/glial fibrillary acidic protein-positive cells).Additionally,the amyloid-beta load in the hippocampus *** findings suggest that multifactor stimulation can enhance adult hippocampal neurogenesis and mitigate amyloid-beta neuropathology in amyloid precursor protein/presenilin 1 ***,cognitive abilities were improved,and depressive symptoms were alleviated in amyloid precursor protein/presenilin 1 mice

关键词： acousto-optic stimulation adult neurogenesis Alzheimer's disease amyloid precursor protein/presenilin 1 mice amyloid-beta deposition brain cell apoptosis cognitive impairment depression-like behavior involuntary treadmill exercise olfactory stimulation serum metabolites

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翻译课及其他——爱荷华大学作家工作坊见闻

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当代文坛 2025年第1期 103-109页

作者：张楚天津市作家协会

通过作者参加爱荷华大学作家工作坊(Iowa Writers’Workshop)两堂英语翻译课的经历,真实、细致地记录了该校作家工作坊的授课方式和特点,进而延宕到作家工作坊的创办历史、招生方式、教学内容等具体情况。通过工作坊的课程安排与国内高... 详细信息

通过作者参加爱荷华大学作家工作坊(Iowa Writers’Workshop)两堂英语翻译课的经历,真实、细致地记录了该校作家工作坊的授课方式和特点,进而延宕到作家工作坊的创办历史、招生方式、教学内容等具体情况。通过工作坊的课程安排与国内高校创写专业课程的比较,从小切口反思了中外创意写作教学中存在的一些共性问题和个性问题,并对中外地域性写作做了剖析,一方面地域性写作的共性叙事主题与美学风格在不断彰显中呈现出新的气象,超越了个体表达的局限性。另外一方面,对写作者按地域分类忽略了小说作为一种艺术表达方式的个性。

关键词：作家工作坊创意写作地域性写作

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Smart Cellulose‑Based Janus Fabrics with Switchable Liquid Transportation for Personal Moisture and Thermal Management

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Nano-Micro Letters 2025年第1期17卷 333-347页

作者： Jianfeng Xi Yanling Lou Liucheng Meng Chao Deng Youlu chu Zhaoyang Xu Huining Xiao Weibing Wu Jiangsu Co‑Innovation Center of Efficient Processing and Utilization of Forest Resources International Innovation Center for Forest Chemicals and MaterialsJiangsu Provincial Key Lab of Sustainable Pulp and Paper Technology and Biomass MaterialsNanjing Forestry UniversityNanjing 210037People’s Republic of China College of Materials Science and Engineering Nanjing Forestry UniversityNanjing 210037People’s Republic of China Department of Chemical Engineering University of New BrunswickFrederictonNB E3B 5A3Canada Macromolecular Chemistry and Bavarian Polymer Institute University of BayreuthBayreuth 95440Germany

The Janus fabrics designed for personal moisture/thermal regulation have garnered significant attention for their potential to enhance human ***,the development of smart and dynamic fabrics capable of managing personal moisture/thermal comfort in response to changing external environments remains a ***,a smart cellulose-based Janus fabric was designed to dynamically manage personal moisture/*** cotton fabric was grafted with N-isopropylacrylamide to construct a temperature-stimulated transport ***,hydrophobic ethyl cellulose and hydrophilic cellulose nanofiber were sprayed on the bottom and top sides of the fabric to obtain wettability *** fabric exhibits anti-gravity directional liquid transportation from hydrophobic side to hydrophilic side,and can dynamically and continuously control the transportation time in a wide range of 3–66 s as the temperature increases from 10 to 40℃.This smart fabric can quickly dissipate heat at high temperatures,while at low temperatures,it can slow down the heat dissipation rate and prevent the human from becoming too *** addition,the fabric has UV shielding and photodynamic antibacterial properties through depositing graphitic carbon nitride nanosheets on the hydrophilic *** smart fabric offers an innovative approach to maximizing personal comfort in environments with significant temperature variations.

关键词： Directional water transport Cotton fabric Anti-gravity directional liquid transportation Janus wettability

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GLOBALLY ATTRACTING SOLUTIONS TO IMPULSIVE FRACTIONAL DIFFERENTIAL INCLUSIONS OF SOBOLEV TYPE

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Acta Mathematica Scientia 2017年第5期37卷 1295-1318页

作者： Van Hien LE dinh Ke TRAN Trong Kinh chu Department of Mathematics Hanoi National University of Education 136 Xuan ThuyCau GiayHanoiVietnam Department of Mathematics Hanoi Pedagogical University No.2VinhphucVietnam

We study a generalized Cauchy problem associated with a class of impulsive fractional differential inclusions of Sobolev type in Banach spaces. Our aim is to prove the existence of a compact set of globally attracting solutions to the problem in question. An application to fractional partial differential equations subject to impulsive effects is given to illustrate our results.

关键词： globally attracting solution impulsive condition nonlocal condition condensing map measure of non-compactness MNC-estimate

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Multilevel analysis of the central-peripheral-target organ pathway:contributing to recovery after peripheral nerve injury

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Neural Regeneration Research 2025年第10期20卷 2807-2822页

作者： Xizi Song Ruixin Li Xiaolei chu Qi Li Ruihua Li Qingwen Li Kai-Yu Tong Xiaosong Gu Dong Ming Academy of Medical Engineering and Translational Medicine Tianjin UniversityTianjinChina Haihe Laboratory of Brain-Machine Interface and Human-Machine Fusion TianjinChina Department of Rehabilitation Tianjin University Tianjin HospitalTianjinChina Department of Hand Microsurgery Tianjin University Tianjin HospitalTianjinChina School of Exercise and Health Tianjin University of SportTianjinChina Department of Biomedical Engineering the Chinese University of Hong KongHong Kong Special Administrative RegionChina

Peripheral nerve injury is a common neurological condition that often leads to severe functional limitations and *** on the pathogenesis of peripheral nerve injury has focused on pathological changes at individual injury sites,neglecting multilevel pathological analysis of the overall nervous system and target *** has led to restrictions on current therapeutic *** this paper,we first summarize the potential mechanisms of peripheral nerve injury from a holistic perspective,covering the central nervous system,peripheral nervous system,and target *** peripheral nerve injury,the cortical plasticity of the brain is altered due to damage to and regeneration of peripheral nerves;changes such as neuronal apoptosis and axonal demyelination occur in the spinal *** nerve will undergo axonal regeneration,activation of Schwann cells,inflammatory response,and vascular system regeneration at the injury *** damage to target organs can occur,including skeletal muscle atrophy and sensory receptor *** then provide a brief review of the research advances in therapeutic approaches to peripheral nerve *** main current treatments are conducted passively and include physical factor rehabilitation,pharmacological treatments,cell-based therapies,and physical ***,most treatments only partially address the problem and cannot complete the systematic recovery of the entire central nervous system-peripheral nervous system-target organ ***,we should further explore multilevel treatment options that produce effective,long-lasting results,perhaps requiring a combination of passive(traditional)and active(novel)treatment methods to stimulate rehabilitation at the central-peripheral-target organ levels to achieve better functional recovery.

关键词： central nervous system central peripheral target organ multilevel pathological analysis nerve regeneration peripheral nerve injury peripheral nervous system target organs therapeutic approach

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Nanomaterials-mediated lysosomal regulation:a robust protein-clearance approach for the treatment of Alzheimer’s disease

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Neural Regeneration Research 2025年第2期20卷 424-439页

作者： Mengqi Hao Jianjian chu Tinglin Zhang Tong Yin Yuankai Gu Wendanqi Liang Wenbo Ji Jianhua Zhuang Yan Liu Jie Gao You Yin Department of Neurology Second Affiliated Hospital of Naval Medical University(Shanghai Changzheng Hospital)ShanghaiChina School of Health Science and Engineering University of Shanghai for Science and TechnologyShanghaiChina Changhai Clinical Research Unit Shanghai Changhai HospitalNaval Medical UniversityShanghaiChina Department of Clinical Pharmacy Xinhua HospitalShanghai Jiao Tong University School of MedicineShanghaiChina Department of Neurology Shanghai East HospitalSchool of MedicineTongji UniversityShanghaiChina

Alzheimer’s disease is a debilitating,progressive neurodegenerative disorder characterized by the progressive accumulation of abnormal proteins,including amyloid plaques and intracellular tau tangles,primarily within the ***,crucial intracellular organelles responsible for protein degradation,play a key role in maintaining cellular *** studies have suggested a link between the dysregulation of the lysosomal system and pathogenesis of neurodegenerative diseases,including Alzheimer’s *** the normal physiological function of lysosomes hold the potential to reduce the pathological burden and improve the symptoms of Alzheimer’s ***,the efficacy of drugs in treating Alzheimer’s disease is limited,with major challenges in drug delivery efficiency and ***,nanomaterials have gained widespread use in Alzheimer’s disease drug research owing to their favorable physical and chemical *** review aims to provide a comprehensive overview of recent advances in using nanomaterials(polymeric nanomaterials,nanoemulsions,and carbon-based nanomaterials)to enhance lysosomal function in treating Alzheimer’s *** review also explores new concepts and potential therapeutic strategies for Alzheimer’s disease through the integration of nanomaterials and modulation of lysosomal *** conclusion,this review emphasizes the potential of nanomaterials in modulating lysosomal function to improve the pathological features of Alzheimer’s *** application of nanotechnology to the development of Alzheimer’s disease drugs brings new ideas and approaches for future treatment of this disease.

关键词： Alzheimer’s disease autophagy dysfunction lysosomal acidification lysosomal system nanomaterials neurodegenerative diseases

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Xi's Visit Enhances Comprehensive Strategic Cooperative Partnership Between Vietnam and China

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China News Release 2024年第1期 39-42页

作者： chu dinh Phuc the Vietnam Academyof Social Sciences Vietnam

Chinese President Xi Jinping paid a state visit to Vietnam at the invitation of Nguyen Phu Trong, general secretary of the Central Committee of the Communist Party of Vietnam, and Vo Van Thuong, president of the Socia... 详细信息

关键词： Vietnam Strategic Communist

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The aging burden of hospitalization for heart failure in Chinese populations:evidence from the Macao Heart Failure Study

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Journal of Geriatric Cardiology 2020年第9期17卷 533-543页

作者： Zhi-Nan LU Mario Evora Edmundo Lao Man Ieng Pun Weng Hong Pun Monica Pon Kong chu Pui I Ieong toi-Meng Mok Yong-Jian WU Coronary Heart Disease Center Cardiology DepartmentFuwai HospitalNational Center for Cardiovascular DiseaseChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina 2Centro Hospitalar Conde de São JanuárioMacaoSARChina

Objective To assess the aging burden of hospitalization for heart failure in Chinese populations in *** The Macao Heart Failure Study consists of patients hospitalized with a diagnosis of acute heart failure(AHF)at Centro Hospitalar Conde de São Januário(the only public hospital that provides medical care for the approximately 600,000 residents of Macao)from January 2014 to December ***,we investigated the relationship between socioeconomic development and epidemiological characteristics of HF in *** we assessed the patients’clinical features and outcomes according to the age *** A total of 967 patients were included in the final *** median age at admission was 82 years *** advanced age at the admission of HF in Macao was significantly associated with a high-income level and the aging population *** heterogeneity existed in the epidemiological characteristics,clinical features,utilization of evidence-based therapies,short-and long-term outcomes,and prognostic utility of clinical variables among the different age *** Rapid economic development and significantly aging populations have produced a profound impact on the epidemiological characteristics of HF in Chinese *** decompensated heart failure(ADHF)is predominantly a disease of the elderly in Macao,and a significant heterogeneity exists in the clinical features,managements,and outcomes among different age ***-based risk stratification models and multidisciplinary HF teams are urgently needed to improve the management and outcomes of hospitalized heart failure(HHF)patients.

关键词： Cardiac risk factors and prevention Heart failure The elderly

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电动拖拉机底盘轻量化设计

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农机化研究 2025年第2期47卷 222-227页

作者：赵南南楚晓杏河南机电职业学院汽车工程学院郑州451191

探讨了电动拖拉机底盘轻量化设计的方法和技术,并基于底盘轻量化的重要性论述了底盘轻量化的具体方法,包括选材、结构优化、工艺改进等方面。针对电动拖拉机的工作特点,提出了适合其底盘轻量化的具体措施,包括采用高强度轻质材料、减少... 详细信息

探讨了电动拖拉机底盘轻量化设计的方法和技术,并基于底盘轻量化的重要性论述了底盘轻量化的具体方法,包括选材、结构优化、工艺改进等方面。针对电动拖拉机的工作特点,提出了适合其底盘轻量化的具体措施,包括采用高强度轻质材料、减少焊接点及优化桥座结构等。最后,通过数值模拟和试验验证了轻量化设计的效果,证明了方法的可行性和有效性。研究成果对于提高电动拖拉机的性能和节能减排具有重要意义。

关键词：电动拖拉机底盘轻量化结构优化

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