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Prognostic effect analysis of molecular subtype on young breast cancer patients

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Chinese Journal of Cancer Research 2015年第4期27卷 428-436页

作者： Hong-Liang Chen Ang ding fu-Wen Wang Department of Breast Surgery Obstetrics and Gynecology Hospital of Fudan University

Objective： To make a prognostic effect analysis of molecular subtype on young breast cancer ***： Totally 187 cases of young breast cancer patients less than 40 years old treated in Obstetrics and Gynecology Hospital of fudan University between June 2005 and June 2011 were included in our study. We described their clinical-pathological characteristics, disease-free survival（DFS） rate, and overall survival（OS） rate after a median follow-up period of 61 months. The factors associated with prognosis were also evaluated by univariate and multivariate ***： All patients were premenopausal, with an average age of 35.36±3.88 years old. The mean tumor size was 2.43±1.53 cm. Eighty-one cases had lymph node metastasis（43.3%）, 126 cases had lymphovascular invasion（67.4%）, and 125 cases had histological grade III（66.8%） disease. Twenty-seven cases（14.4%） were Luminal A subtype, 99 cases（52.9%） were Luminal B subtype, 29 cases（15.5%） were human epidermal growth factor receptor 2（HER-2） overexpression subtype, while 32 cases（17.1%） were triple negative breast cancer（TNBC） subtype according to 2013 St Gallen expert consensus. One hundred and thirty-five cases underwent mastectomy whereas 52 cases had breast-conserving surgery. One hundred and seventy-eight cases underwent adjuvant or neoadjuvant chemotherapy. Recurrence or metastasis occurred in 29 cases, 13 of which died. The 5-year DFS and OS rates were 84% and 92%. Multivariate analysis showed that nodal status（P=0.041） and molecular subtype（P=0.037） were both independent prognostic factors of DFS, while nodal status（P=0.037） and TNBC subtype（P=0.048） were both independent prognostic factors of OS. Conclusions： Molecular subtype is an independent prognostic factor of young breast cancer patients. TNBC has a high risk of relapse and death.

关键词： Molecular subtype young breast cancer prognosis

Estimates for the ruin probability of a time-dependent renewal risk model with dependent by-claims

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Applied Mathematics(A Journal of Chinese Universities) 2015年第3期30卷 347-360页

作者： fu Ke-ang QIU Yu-yang WANG An-ding School of Statistics and Mathematics Zhejiang Gongshang University

Consider a continuous-time renewal risk model, in which every main claim induces a delayed by-claim. Assume that the main claim sizes and the inter-arrival times form a sequence of identically distributed random pairs, with each pair obeying a dependence structure, and so do the by-claim sizes and the delay times. Supposing that the main claim sizes with by-claim sizes form a sequence of dependent random variables with dominatedly varying tails, asymptotic estimates for the ruin probability of the surplus process are investigated, by establishing a weakly asymptotic formula, as the initial surplus tends to infinity.

关键词： by-claim dominatedly varying tail extended upper negative dependence quasi-asymptotic independence ruin probability time-depende

Tribology of nitriding layer, TiN coatings and their complex on AISI D2 steel

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中国有色金属学会会刊：英文版 2004年第z1期14卷 383-385页

作者： WANG Ke-sheng ZHANG De-yuan DONG ding-fu College of Materials Science and Engineering Hefei University of Technology Hefei 230009 China Yu King Industrial Company Limited Shenzhen 518103 China College of Materials Science and Engineering Hefei University of Technology Hefei 230009 China National R&D Centre for Surface Engineering of China Shenzhen 518029 China College of Materials Science and Engineering Hefei University of Technology Hefei 230009 China

The sliding wear and impact wear resistances of D2 steel with nitriding layer, PVD titanium nitride coating and their duplex treatment were investigated. The experimental results suggest that the duplex treatment has the best sliding and impact wear resistances under experimental conditions. And the wear resistance of PVD titanium nitride is better than that of nitriding. The impact wear resistance and wear mechanism of all three surface layers remain unchanged under impact load of 0.2 J or 1 J. All samples end with the same symptom of flaking.

关键词： wear resistance titanium nitride nitriding duplex treatment

Comparative investigation on high-speed grinding of TiCp/Ti–6Al–4V particulate reinforced titanium matrix composites with single-layer electroplated and brazed CBN wheels

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Chinese Journal of Aeronautics 2016年第5期29卷 1414-1424页

作者： Li Zheng ding Wenfeng Shen Long Xi Xinxin fu Yucan College of Mechanical and Electrical Engineering Nanjing University of Aeronautics and Astronautics

In order to develop the high-efficiency and precision machining technique of TiCp/Ti - 6Al-4V particulate reinforced titanium matrix composites （PTMCs）, high-speed grinding experiments were conducted using the single-layer electroplated cubic boron nitride （CBN） wheel and brazed CBN wheel, respectively. The comparative grinding performance was studied in terms of grinding force, grinding temperature, grinding-induced surface features and defects. The results display that the grinding forces and grinding temperature obtained with the brazed CBN wheel are always lower than those with the electroplated CBN wheel. Though the voids and microcracks are the dominant grinding-induced surface defects, the brazed CBN wheel produces less surface defects compared to the electroplated wheel according to the statistical analysis results. The max mum materials removal rate with the brazed CBN wheel is much higher than that with the electroplated one. All above indicate that the single-layer brazed CBN super-abrasive wheel is more suitable for high-speed grinding of PTMCs than the electroplated counterpart.

关键词： High-speed grinding PTMCs Single-layer brazed CBNwheel Single-layer electroplated CBN wheel Surface defects

Recent progress in synthesis and properties of 2D room-temperature ferromagnetic materials

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Science China Chemistry 2023年第11期66卷 3054-3069页

作者： Lixuesong Han Tingting Cheng Yiran ding Mengqi Zeng Lei fu College of Chemistry and Molecular Sciences Wuhan UniversityWuhan 430072China

Two-dimensional(2D)ferromagnetic materials have important applications in optics,spintronics,biomedicine,and energy conversion *** achieve higher integration and continue Moore's Law,it is necessary to search for 2D ferromagnetic ***,the low Curie temperature(Tc)of most 2D ferromagnetic materials seriously hinders their practical ***,the search for room-temperature 2D ferromagnetic materials is of great significance for the advancement of technological *** article provides a systematic and comprehensive review of the synthesis methods of room-temperature 2D ferromagnetic materials that have been discovered and created to date,as well as an overview of the physical properties of the 2D ferromagnetic ***,the challenges and prospects of the room-temperature 2D ferromagnetic materials in the fields of synthesis and application are briefly summarized.

关键词： two-dimensional ferromagnetic room-temperature synthesis

Active generalized predictive control of turbine tip clearance for aero-engines

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Chinese Journal of Aeronautics 2013年第5期26卷 1147-1155页

作者： Peng Kai fan ding Yang fan fu Qiang Li Yong School of Power and Energy Northwestern Polytechnical University Aeronautics and Astronautics Engineering College Air Force Engineering University School of Flight Technology Civil Aviation Flight University of China

Active control of turbine blade tip clearance continues to be a concern in design and control of gas turbines. Ever increasing demands for improved efficiency and higher operating temperatures require more stringent tolerances on turbine tip clearance. In this paper, a turbine tip clearance control apparatus and a model of turbine tip clearance are proposed; an implicit active generalized predictive control （GPC）, with auto-regressive （AR） error modification and fuzzy adjustment on control horizon, is presented, as well as a quantitative analysis method of robust per- turbation radius of the system. The active clearance control （ACC） of aero-engine turbine tip clear- ance is evaluated in a lapse-rate take-off transient, along with the comparative and quantitative analysis of the stability and robustness of the active tip clearance control system. The results show that the resultant active tip clearance control system with the improved GPC has favorable steadystate and dynamic performance and benefits of increased efficiency, reduced specific fuel consump- tion, and additional service life.

关键词： Active clearance control(ACC) Aero-engine Aircraft Generalized prcdictivc control (GPC) Global convergence Robust perturbation radius Turbine tip clearance

Frequency domain based super-resolution method for mixed-resolution multi-view images

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Journal of Systems Engineering and Electronics 2016年第6期27卷 1303-1314页

作者： Zhizhong fu Yawei Li Yuan Li Lan ding Keyu Long School of Communication and Information Engineering University of Electronic Science and Technology of ChinaChengdu 611731China The Second Research Institute of Civil Aviation Administration of China Chengdu 610041China

Super-resolution (SR) techniques, which are based on single or multi-frame low-resolution (LR) images, have been extensively investigated in the last two decades. Mixed-resolution multiview video format plays an important role in three-dimensional television (3DTV) coding scheme. Previous work considers multiview or multi-camera images and videos at the same resolution, which performs well under the planar model without or with little projection error among the videos captured by different cameras. In recent years, several researchers have discussed the SR problem in mixed-resolution multi-view video format, where the superresolved image is created using the up-sampled version of the LR image and the high frequency components extracted from the warped image in the adjacent high-resolution (HR) views. Unfortunately, the output HR images suffer from artifacts caused by depth error. To obtain the detailed texture and edge information from the HR image as much as possible, while preserving the structure of the LR image, a novel SR reconstruction algorithm is proposed. The algorithm is composed of three components: the structure term, the detail information term, and the regularization term. The first term preserves the structure similarity of the LR image; the second term extracts detailed information from the adjacent HR image; and the last term ensures the uniqueness of the solution. Experimental results show the effectiveness and robustness of the proposed algorithm, which achieves high performance both subjectively and objectively. © 2016 Beijing Institute of Aerospace Information.

关键词： Cameras Edge detection Frequency domain analysis Image reconstruction Optical resolving power

Sintering of monoclinic SrAl_(2)Si_(2)O_(8) ceramics and their Sr immobilization

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International Journal of Minerals,Metallurgy and Materials 2021年第6期28卷 1057-1062页

作者： Jie Luo Xin Li fu-jie Zhang Song Chen ding Ren Key Laboratory of Radiation Physics and Technology of Ministry of Education Institute of Nuclear Science and TechnologySichuan UniversityChengdu 610065China Nuclear Power Institute of China Chengdu 610005China Department of Radiotherapy Division of Radiation PhysicsState Key Laboratory of Biotherapy and Cancer CenterWest China HospitalSichuan UniversityChengdu 610041China School of Materials Science and Engineering Southwest Jiaotong UniversityChengdu 610031China

Monoclinic SrAl_(2)Si_(2)O_(8) ceramics for Sr immobilization were prepared by a liquid-phase sintering *** sintering temperature,mineral phase composition,microstructure,flexural strength,bulk density,and Sr ion leaching characteristics of the SrAl_(2)Si_(2)O_(8) ceramics were investigated.A crystalline monoclinic SrAl_(2)Si_(2)O_(8) phase formed through liquid-phase sintering at 1223 *** introduction of four flux agents(B_(2)O_(3),CaO·2B_(2)O_(3),SrO·2B_(2)O_(3),and BaO·2B_(2)O_(3))to the SrAl_(2)Si_(2)O_(8) ceramics not only reduced the densification temperature and decreased the volatilization of Sr during high-temperature sintering but also impacted the mechanical properties of the *** consistency tests showed that the leaching concentration of Sr ions in the sample with flux agent B_(2)O_(3) was the lowest,whereas that of Sr ions in the sample with flux agent BaO·2B_(2)O_(3) was the *** results show that the leaching concentration of Sr ions depends largely on the amorphous phase in the ***,the formation of mineral analog ceramics containing Sr is an important factor to improve Sr immobilization.

关键词： low-temperature liquid-phase sintering strontium immobilization monoclinic strontium feldspar flux agent

Study on the Synthesis and Properties of PET Using Hydrotalcite as Catalyst

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China Petroleum Processing & Petrochemical Technology 2013年第3期15卷 65-69页

作者： Li Guihe fu Zhifeng Cao ding State Key Laboratory of Chemical Resource Engineering Beijing University of Chemical Technology

Poly(ethylene terephthalate)(PET)was synthesized by the in-situ polymerization method using layered double hydrotalcite(LDH)as the catalyst,and the thermal and flame retardation properties of PET were investigated as *** identified by differential scanning calorimetry(DSC)and thermogravimetric(TGA)analysis,the crystallization rate and thermal degradation temperature of the as-prepared PET sample were enhanced compared with commercial PET *** was confirmed from the fire-resistant property study that the LDH can be used as an efficient flame-retardant besides functioning as a catalyst in the transesterification/polycondensation process for PET synthesis.

关键词： poly(ethylene terephthalate) layered double hydrotalcite transesterification polycondensation catalyst