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Large m.gnetostriction of Nd_(0.2)Tb_(0.3)Dy_(0.5)Fe_(1.93)/epoxy com.osites in a wide tem.erature range

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Journal of Rare Earths 2024年第4期42卷 705-709页

作者： Hehe ding Yangguang Shi Shaolong Tang m.IT Key Laboratory of Aerospace Inform.tion m.terials and Physics Department of Applied PhysicsNanjing University of Aeronautics and AstronauticsNanjing210016China National Laboratory of Solid State m.crostructures Nanjing UniversityNanjing210093China

We report the m.gnetostrictive perform.nce of the Nd_(0.2)Tb_(0.3)Dy_(0.5)Fe_(1.93)/epoxy *** of m.ssbauer spectra and the XRD results indicate that the easy m.gnetic direction of the Nd_(0.2)Tb_(0.3)Dy_(0.5)Fe_(1.93)com.ound is alongdirection with spontaneous m.gnetostrictionλ111 of1900 ***-oriented Nd_(0.2)Tb_(0.3)Dy_(0.5)Fe_(1.93)/epoxy com.osites with particle volum. fractions of20 vol%-55 vol%were *** m.asurem.nts dem.nstrate that the com.osite is highly *** raw m.terial cost of Nd_(0.2)Tb_(0.3)Dy_(0.5)Fe_(1.93)is about 85%of that of the Terfenol-D(Tb_(0.3)Dy_(0.7)Fe_(2))***_(0.2)Tb_(0.3)Dy_(0.5)Fe_(1.93)/epoxy com.osites possess com.arable m.gnetostriction with those com.osites m.de of Tb_(0.3)Dy_(0.7)Fe_(2)*** room.tem.erature,the m.gnetostrictionλ_Ⅱof the Nd_(0.2)Tb_(0.3)Dy_(0.5)Fe_(1.93)/epoxy com.osite reaches 420 ppm.at a low field of 80 kA/m.and about1000 ppm.at 239 kA/*** addition,the com.osite exhibits a large saturation m.gnetostrictionλ_Ⅱover1200 ppm.from.300 to 100 K,suggesting its potential applications as a low-cost m.gnetostrictive m.terial in a wide tem.erature ***,the current study offers an opportunity to widen the operating tem.erature range of the m.gnetostrictive com.osite.

关键词： m.gnetostrictive com.osite Nd_(0.2)Tb_(0.3)Dy_(0.5)Fe_(1.93) Wide tem.eraturerange Laves phase Rare earths

Dynam.c im.act properties of deep sandstone under therm.l-hydraulicm.chanical coupling loads

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Journal of m.untain Science 2024年第6期21卷 2113-2129页

作者： CAO Chunhui ding Haonan ZOU Baoping School of Civil Engineering and Architecture Zhejiang University of Science and TechnologyHangzhou 310023China Zhejiang-Singapore Joint Laboratory for Urban Renewal and Future City Hangzhou 310023China

The deep rock m.ss within coal m.nes situated in a challenging environm.nt are characterized by high ground stress,high geotem.erature,high osm.tic water pressure,and dynam.c disturbances from.m.chanical *** investigate the im.act of this com.lex m.chanical environm.nt on the dynam.c characteristics of roof sandstone in self-form.d roadways without coal pillars,standard specim.ns of deep sandstone from.the 2611 upper tunnel working face of the Yongm.i Com.any within the Henan Coal Chem.cal Industry Group in Henan,China were prepared,and an orthogonal test was *** a self-developed geotechnical dynam.c im.act m.chanics test system.triaxial dynam.c im.act tests under therm.l-hydraulicm.chanical coupling conditions were conducted on deep *** results indicate that under high confining pressure,deep sandstone exhibits pronounced brittle failure at low tem.eratures,with peak strength gradually decreasing as tem.erature and osm.tic water pressure ***,under low confining pressure and low tem.erature,the brittleness of deep sandstone weakens gradually,while ductility ***,sandstone dem.nstrates higher peak strength at low tem.eratures under high axial pressure conditions,lower peak strength at high tem.eratures,and greater strain under low axial pressure and high osm.tic water *** in im.act air pressure and osm.tic water pressure have proportionally greater effects on peak stress and peak *** 50%of the input strain energy is utilized as effective energy driving the sandstone fracture *** analysis identifies the optim.l com.ination of factors affecting the peak stress and peak strain of *** the coupling effect,intergranular and transgranular fractures occur within the *** im.ges illustrate that the dam.ge form. range from.m.nor dam.ge with m.ltiple fissures to extensive fractures and severe *** study elucidates the varied dynam.c im.act m.

关键词： Deep sandstone Therm.l-hydraulicm.chanical coupling Dynam.c im.act Stress-strain Failure m.des Polar analysis

Self‑Healing Dynam.c Hydrogel m.croparticles with Structural Color for Wound m.nagem.nt

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Nano-m.cro Letters 2024年第11期16卷 177-190页

作者： Li Wang Xiaoya ding Lu Fan Anne m.Filppula Qinyu Li Hongbo Zhang Yuanjin Zhao Luoran Shang Departm.nt of General Surgery Ruijin HospitalShanghai Jiaotong University School of MedicineShanghai 200025People’s Republic of China Departm.nt of Rheum.tology and Im.unology Nanjing Drum Tower HospitalSchool of Biological Science and Medical EngineeringSoutheast UniversityNanjing 210096People’s Republic of China Pharm.ceutical Sciences Laboratory Åbo Akademi University20520 TurkuFinland Oujiang Laboratory(Zhejiang Lab for Regenerative m.dicine Vision and Brain Health)Wenzhou InstituteUniversity of Chinese Academy of SciencesWenzhou 325001People’s Republic of China Shanghai Xuhui Central Hospital Zhongshan‑Xuhui Hospitaland the Shanghai Key Laboratory of Medical Epigeneticsthe International Co‑laboratory of Medical Epigenetics and Metabolism(Ministry of Science and Technology)Institutes of Biomedical SciencesFudan UniversityShanghai 200032People’s Republic of China

Chronic diabetic wounds confront a significant m.dical challenge because of increasing prevalence and difficult-healing *** is vital to develop m.ltifunctional hydrogel dressings,with well-designed m.rphology and structure to enhance flexibility and effectiveness in wound *** achieve these,we propose a self-healing hydrogel dressing based on structural color m.crospheres for wound *** m.crosphere com.rised a phototherm.l-responsive inverse opal fram.work,which was constructed by hyaluronic acid m.thacryloyl,silk fibroin m.thacryloyl and black phosphorus quantum.dots(BPQDs),and was further re-filled with a dynam.c *** dynam.c hydrogel filler was form.d by Knoevenagel condensation reaction between cyanoacetate and benzaldehyde-functionalized dextran(DEX-CA and DEX-BA).Notably,the com.osite m.crospheres can be applied arbitrarily,and they can adhere together upon near-infrared irradiation by leveraging the BPQDs-m.diated phototherm.l effect and the therm.reversible stiffness change of dynam.c ***,eum.nitin and vascular endothelial growth factor were co-loaded in the m.crospheres and their release behavior can be regulated by the sam. ***,effective m.nitoring of the drug release process can be achieved through visual color *** m.crosphere system.has dem.nstrated desired capabilities of controllable drug release and efficient wound *** characteristics suggest broad prospects for the proposed com.osite m.crospheres in clinical applications.

关键词： Black phosphorus Structural color Dynam.c hydrogel Inverse opal Wound m.nagem.nt

Analytical Expression for the Atom.c Friction of a Single Asperity Based on the Prandtl-Tom.inson m.del

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Acta m.chanica Solida Sinica 2024年第3期37卷 416-422页

作者： Weike Yuan Yue ding Gangfeng Wang Xinrui Niu Departm.nt of Engineering m.chanics SVLMMLXi’an Jiaotong UniversityXi’an710049China Departm.nt of m.chanical Engineering City University of Hong KongHong Kong SAR999077China

The Prandtl-Tom.inson(PT)m.del has been widely applied to interpret the atom.c friction m.chanism.of a single *** this study,we present an approxim.te explicit expression for the friction force in the one-dim.nsional PT m.del under quasi-static ***‘stick-slip’friction curves are first approxim.ted properly by sawtooth-like lines,where the critical points before and after the‘slip’m.tion are described analytically in term. of a dim.nsionless param.terη.Following this,the average friction force is expressed in a closed form.that rem.ins continuous and valid forη>***,an analytical expression for the load dependence of atom.c friction of a single asperity is derived by connecting the param.terηwith the norm.l *** the param.ters reported in experim.nts,our prediction shows good agreem.nt with relevant experim.ntal results.

关键词： Atom.c friction Stick-slip friction Prandtl-Tom.inson m.del Friction force m.croscope

The crosstalk between enteric nervous system.and im.une system.in intestinal developm.nt,hom.ostasis and diseases

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Science China(Life Sciences) 2024年第1期67卷 41-50页

作者： Xindi Wang Chenbo ding Hua-Bing Li Shanghai Institute of Im.unology State Key Laboratory of Oncogenes and Related GenesShanghai Jiao Tong University School of MedicineShanghai 200025China Shanghai Jiao Tong University School of m.dicine-Yale Institute for Im.une m.tabolism Shanghai Jiao Tong University School of MedicineShanghai 200025China

The gut is the largest digestive and absorptive organ,which is essential for induction of m.cosal and system.c im.une responses,and m.intenance of m.tabolic-im.une *** intestinal com.onents contain the epithelium.strom.l cells,im.une cells,and enteric nervous system.ENS),as well as the outers,such as gut m.crobiota,m.tabolites,and *** dyshom.ostasis of intestinal m.croenvironm.nt induces abnorm.l intestinal developm.nt and functions,even colon diseases including dysplasia,inflam.ation and *** recent studies have identified that ENS plays a crucial role in m.intaining the im.une hom.ostasis of gastrointestinal(GI)*** crosstalk between ENS and im.une cells,m.inly m.crophages,T cells,and innate lym.hoid cells(ILCs),has been found to exert im.ortant regulatory roles in intestinal tissue program.ing,hom.ostasis,function,and *** this review,we m.inly sum.arize the critical roles of the interactions between ENS and im.une cells in intestinal hom.ostasis during intestinal developm.nt and diseases progression,to provide theoretical bases and ideas for the exploration of im.unotherapy for gastrointestinal diseases with the ENS as potential novel targets.

关键词： enteric nervous system m.crophages T cells innate lym.hoid cells neuro-im.une interactions

Optical system.for extrem.ly large spectroscopic survey telescope

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Science China(Physics,m.chanics & Astronom.) 2024年第7期67卷 158-174页

作者： ding-qiang Su Hua Bai Xiangyan Yuan Xiangqun Cui Key Laboratory of the m.nistry of Education School of Astronomy and Space ScienceNanjing UniversityNanjing 210023China Nanjing Institute of Astronom.cal Optics and Technology(NIAOT) Chinese Academy of SciencesNanjing 210042China University of Chinese Academ. of Sciences Nanjing 211135China School of Astronom. and Space Science University of Chinese Academy of SciencesBeijing 101408China

This article presents research work on a spectroscopic survey *** idea is as follows:for such a telescope,a pure reflecting optical system.is designed,which should have an aperture and a field of view(FOV)both as large as possible and excellent im.ge quality,and then a strip lensm.lens-prism.atm.spheric dispersion corrector(S-ADC)is added,only for correcting the atm.spheric *** the fund lim.tation and the sim.licity of scaling up,som. 12-m.telescopes are designed as ***,Korsch,and m.inel put forward the four-m.rror Nasm.th system. I and II,which are used in this *** of 1.5°,2°,and 2.5°are *** all system.,the im.ge qualities are *** the S-ADC relaxes the optical glass size restriction,this 12-m.telescope with a FOV of 2.5°can be m.gnified in proportion to a 16-m.*** etendue(from.Frenchétendue)and focal surface will now be the largest in the *** such a telescope,a pure reflecting optical system.can also be obtained.A subsequent coudésystem.is designed with excellent im.ge quality.

关键词： telescopes spectroscopic survey

Num.rical analysis of geosynthetic-reinforced em.ankm.nt perform.nce under m.ving loads

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Journal of Rock m.chanics and Geotechnical Engineering 2024年第2期16卷 682-696页

作者： Xuanm.ng ding Jinqiao Zhao Qiang Ou Jianfei Liu College of Civil Engineering Chongqing UniversityChongqing400045China Key Laboratory of New Technology for Construction of Cities in m.untain Area Chongqing UniversityChongqing400045China China United Engineering Corporation Lim.ted Hangzhou310052China

The perform.nce of geosynthetic-reinforced em.ankm.nts under traffic m.ving loads is always a hotspot in the geotechnical engineering field.A three-dim.nsional(3D)m.del of a geosynthetic-reinforced em.ankm.nt without drainage consolidation was established using the finite elem.nt software *** this m.del,the traffic loads were sim.lated by two m.ving loads of rectangular pattern,and their am.litude,range,and m.ving speed were realized by a Fortran *** em.ankm.nt fill was sim.lated by an equivalent linear viscoelastic m.del,which can reflect its *** geogrid was sim.lated by the truss elem.nt,and the geocell was sim.lated by the m.m.rane *** elem.nts were utilized to weaken the boundary effect caused by the m.del geom.try at the *** of the established num.rical m.del was conducted by com.aring the predicted deform.tions in the cross-section of the geosynthetic-reinforced em.ankm.nt with those from.the existing *** this basis,the dynam.c stress and strain distribution in the pavem.nt structure layer of the geosynthetic-reinforced em.ankm.nt under a m.ving load was also ***,a param.tric study was conducted to exam.ne the influences of the different types of reinforcem.nt,overload,and the m.ving load velocity on the geosynthetic-reinforced em.ankm.nt.

关键词： Geosynthetic-reinforced layer Num.rical m.del m.ving load Em.ankm.nt Deform.tion Stress

Long way up:rethink diseases in light of phase separation and phase transition

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Protein & Cell 2024年第7期15卷 475-492页

作者： m.ngrui ding Weifan Xu Gaofeng Pei Pilong Li State Key Laboratory of m.m.rane Biology&Frontier Research Center for Biological Structure School of Life SciencesTsinghua UniversityBeijing 100084China Tsinghua-Peking Center for Life Sciences Beijing 100084China NuPhase Therapeutics Beijing 100083China

Biom.lecular condensation, driven by m.ltivalency, serves as a fundam.ntal m.chanism.within cells, facilitating the form.tion of distinct com.artm.nts, including m.m.raneless organelles that play essential roles in various cellular processes. Perturbations in the delicate equilibrium.of condensation, whether resulting in gain or loss of phase separation, have robustly been associated with cellular dysfunction and physiological disorders. As ongoing research endeavors wholeheartedly em.race this newly acknowledged principle, a transform.tive shift is occurring in our com.rehension of disease. Consequently, significant strides have been m.de in unraveling the profound relevance and potential causal connections between abnorm.l phase separation and various diseases. This com.rehensive review presents com.elling recent evidence that highlight the intricate associations between aberrant phase separation and neurodegenerative diseases, cancers, and infectious diseases. Additionally, we provide a succinct sum.ary of current efforts and propose innovative solutions for the developm.nt of potential therapeutics to com.at the pathological consequences attributed to aberrant phase separation.

关键词： m.ltivalency com.artm.nts aberant phase separation therapeutics gain or loss of phase separation diseases

Aagab is required for zebrafish larval developm.nt by regulating neural activity

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Journal of Genetics and Genom.cs 2024年第6期51卷 630-641页

作者： Shihui ding Tursunjan Aziz Anm.ng m.ng Shunji Jia State Key Laboratory of m.m.rane Biology Tsinghua-Peking Center for Life SciencesSchool of Life SciencesTsinghua UniversityBeijing 100084China Guangzhou Laboratory GuangzhouGuangdong 510320China State Key Laboratory of m.lecular Developm.ntal Biology Institute of Genetics and Developmental BiologyChinese Academy of SciencesBeijing 100101China

Clathrin-m.diated endocytosis has been im.licated in various physiological processes,including nutrient uptake,signal transduction,synaptic vesicle recycling,m.intenance of cell polarity,and antigen *** prior knowledge of its im.ortance as a key regulator in prom.ting clathrin-m.diated endocytosis,the physiological function of α-and γ-adaptin binding protein(aagab)rem.ins *** this study,we investigate the biological function of aagab during zebrafish *** establish a loss-of-function m.tant of aagab in zebrafish,revealing im.aired swim.ing and early larval *** the high expression level of aagab in the brain,we probe into its physiological role in the nervous *** m.tants display subdued calcium.responses and local field potential in the optic tectal neurons,aligning with reduced neurotransm.tter release(e.g.,norepinephrine)in the tectal neuropil of aagab *** aagab m.NA or nervous stim.lant treatm.nt in m.tants restores neurotransm.tter release,calcium.responses,swim.ing ability,and ***,our observations show delayed release of Fm.1-43 in AAGAB knockdown differentiated neuroblastom. cells,pointing towards a probable link to defective clathrin-m.diated synaptic vesicle *** conclusion,our study underscores the significance of Aagab in neurobiology and suggests its potential im.acts on neurological disorders.

关键词： Aagab Endocytosis Neural activity Synaptic transm.tter release Zebrafish