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A Multilayer Network Constructed for Herb and Prescription Efficacy Analysis

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Computer Systems Science & Engineering 2024年第3期48卷 691-704页

作者： Xindi Huang liwei Liang Sakirin Tam Hao Liang Xiong Cai Changsong ding School of Informatics Hunan University of Chinese MedicineChangsha410208China Faculty of Science and Information Technology Phnom Penh International UniversityPhnom Penh12253Cambodia institute of TCM Diagnostics Hunan University of Chinese MedicineChangsha410208China institute of Innovation and Applied Research in Chinese Medicine Hunan University of Chinese MedicineChangsha410208China Big Data Analysis Laboratory of Traditional Chinese Medicine Hunan University of Chinese MedicineChangsha410208China

Chinese Medicine(CM)has been widely used as an important avenue for disease prevention and treatment in china especially in the form of CM prescriptions combining sets of herbs to address patients’symptoms and ***,the selection and compatibility of herbs are complex and abstract due to intrinsic relationships between herbal properties and their overall *** analysis is applied to demonstrate the complex relationships between individual herbal efficacy and the overall function of CM *** illustrate their connections and correlations,prescription function(PF),prescription herb(PH),and herbal efficacy(HE)intranetworks are proposed based on CM theory to identify relationships between herbs and *** three networks are then connected by PF-PH and PH-HE interlayer networks adopting herb dosage to form a multidimensional heterogeneous network,a Prescription-Herb-Function Network(PHFN).The network is applied to 112.classic prescriptions from Treatise on Exogenous Febrile and Miscellaneous Diseases to illustrate the application of *** PHFN is constructed including 146 functions in PF intra network,89 herbs in the PH intra network,and 163 herbal efficacies in the HE intra *** results show that herb pairs with synergistic actions have stronger relevance,such as licorice-cassia twig,licorice-Chinese date,fresh ginger-Chinese date,*** integration of dosage to the network helps to indicate the main herbs for cluster analysis and automatic *** also reveals the internal relationships between the functions of prescriptions and composed herbal efficacies.

关键词： Chinese medicine herb formula network analysis herb dosage

Dynamical symmetric group approach to potential energy surface of molecule O_3

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Chinese Science Bulletin 2000年第4期45卷 331-334页

作者： ZHENG Yujun & ding Shilianginstitute of Theoretical Chemistry, {2. University, jinan 2.0100, china institute of Theoretical Chemistry Shandong University Jinan China

Hamiltonian of an O3 molecule is classicized by using coherent states, and its potential energy surface is obtained. The surface and the contours are plotted. The calculated force constants and dissociation energies a... 详细信息

关键词： dynamical symmetric group potential energy surface molecule 03.

Natural vibration and critical velocity of translating Timoshenko beam with non-homogeneous boundaries

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Applied Mathematics and Mechanics(English Edition) 2024年第9期45卷 1523-1538页

作者： Yanan LI Jieyu ding Hu ding Liqun CHEN Shanghai institute of Applied Mathematics and Mechanics Shanghai Key Laboratory of Mechanics in Energy EngineeringShanghai Frontier Science Center of MechanoinformaticsSchool of Mechanics and Engineering ScienceShanghai UniversityShanghai 200072China School of Mathematics and Statistics Qingdao UniversityQingdao 266071Shandong ProvinceChina

In most practical engineering applications,the translating belt wraps around two fixed *** boundary conditions of the dynamic model are typically specified as simply supported or fixed *** this paper,non-homogeneous boundaries are introduced by the support *** the translating belt as the mechanical prototype,the vibration characteristics of translating Timoshenko beam models with nonhomogeneous boundaries are investigated for the first *** governing equations of Timoshenko beam are deduced by employing the generalized Hamilton's *** effects of parameters such as the radius of wheel and the length of belt on vibration characteristics including the equilibrium deformations,critical velocities,natural frequencies,and modes,are numerically calculated and *** numerical results indicate that the beam experiences deformation characterized by varying curvatures near the *** radii of the wheels play a pivotal role in determining the change in trend of the relative difference between two beam *** the results unearths that the relative difference in equilibrium deformations between the two beam models is more pronounced with smaller-sized *** the two wheels are of equal size,the critical velocities of both beam models reach their respective *** addition,the relative difference in natural frequencies between the two beam models exhibits nonlinear variation and can easily exceed 50%.Furthermore,as the axial velocities increase,the impact of non-homogeneous boundaries on modal shape of translating beam becomes more *** dealing with non-homogeneous boundaries is challenging,beam models with non-homogeneous boundaries are more sensitive to parameters,and the differences between the two types of beams undergo some interesting variations under the influence of non-homogeneous boundaries.

关键词： translating beam Timoshenko beam non-homogeneous boundary natural frequency critical velocity

The isotopic effects in the IR-multiphoton excitation of molecules with c_(2.) symmetry

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Chinese Journal of Chemistry 1993年第4期11卷 321-328页

作者： ding,Shi-Liang LIU,Wen-Jian DENG,Cong-Hao institute for theoretical chemistry,{2. University,jinan,{2. 2.0100 institute for theoretical chemistry. shandong University Jinan Shandong 250100

Quantum dynamical calculations for the IR-multiphoton excitation of H_2.,D_2. and T_2. are presented using a generalized Hamiltonian for XY_2.*** energy spectra obtained from this Hamiltonian are in good agreement with those of the *** long time average of the transition probabilities and the isotopic effects are discussed in detail,

关键词： The isotopic effects in the IR-multiphoton excitation of molecules with c symmetry IR

Targeted nanostrategies eliminate pre-metastatic niche of cancer

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Nano Research 2024年第6期17卷 5358-5373页

作者： Juan Wang Ning Zhang Xiuping ding Chengrui Fu Xiaodong Li Baosheng Li Jianxun ding Tianmeng Sun Key Laboratory of Organ Regeneration and Transplantation of Ministry of Education Institute of ImmunologyThe First HospitalJilin University1 Xinmin StreetChangchun 130061China Key Laboratory of Polymer Ecomaterials Changchun Institute of Applied ChemistryChinese Academy of Sciences5625 Renmin StreetChangchun 130022China Department of Radiation Oncology Shandong Cancer Hospital and InstituteShandong First Medical University and Shandong Academy of Medical Sciences440 Jiyan RoadJinan 250117China Department of orthopaedics The Second Hospital of Shandong UniversityShandong University247 Beiyuan StreetJinan 250033China State Key Laboratory of Molecular Engineering of Polymers Fudan University220 Handan RoadShanghai 200433China

Establishing a pre-metastatic niche(PMN)in secondary organs is a prerequisite for cancer *** advances in cancer therapy,the efficient inhibition of PMN formation remains a clinical *** advances in understanding the specific characteristics of PMN and advances in nanotechnology have provided hope for manipulating their microenvironments.A series of nanostrategies have been designed to eliminate the PMN,including the removal of pro-metastatic exosomes from the bloodstream for excretion via the intestines,the targeting and scavenging of myeloid-derived suppressor cells,fibroblasts,and critical extracellular matrix components,and the elimination of circulating tumor cells prior to colonization in distant *** review summarizes the underlying mechanisms of PMN formation,highlights the anti-PMN efficacy of currently reported nanostrategies,and underlines the unresolved questions.

关键词： nanoparticle controlled drug delivery pre-metastatic niche elimination metastasis suppression cancer therapy

MYB2.and MYB108 regulate lateral root development by interacting with LBD2. in Arabidopsis thaliana

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Journal of Integrative Plant Biology 2024年第8期66卷 1675-1687页

作者： Feng Zhang Junxia Wang Tingting ding Xuefeng Lin Haiying Hu Zhaojun ding Huiyu Tian The Key Laboratory of Plant Development and Environmental Adaptation Biology Ministry of EducationSchool of Life SciencesShandong UniversityQingdao 266237China Advanced Medical Research institute Cheeloo College of MedicineShandong UniversityJinan 250012China

AUXIN RESPONSE FACTOR 7(ARF7)-mediated auxin signaling plays a key role in lateral root(LR)development by regulating downstream LATERAL ORGAN BOUNDARIES DOMAIN(LBD)transcription factor genes,including LBD16,LBD18,and *** proteins are believed to regulate the transcription of downstream genes as homodimers or ***,whether LBD2. forms dimers with other proteins to regulate LR development remains ***,we determined that the Arabidopsis thaliana(L.)*** transcription factors MYB2.and MYB108 interact with LBD2. and regulate auxin-induced LR *** MYB2.and MYB108 were induced by auxin in an ARF7-dependent *** of MYB2.by fusion with an SRDX domain severely affected auxin-induced LR formation and the ability of LBD2. to induce LR *** contrast,overexpression of MYB2.or MYB108 resulted in greater LR numbers,except in the lbd2. mutant *** findings underscore the interdependence and importance of MYB2.MYB108,and LBD2. in regulating LR *** addition,MYB2.LBD2. and MYB108–LBD2. complexes promoted the expression of CUTICLE DESTRUCTING FACTOR 1(CDEF1),a member of the GDSL(Gly-Asp-Ser-Leu)lipase/esterase family involved in LR *** summary,this study identified MYB2.LBD2. and MYB108–LBD2. regulatory modules that act downstream of ARF7 and intricately control auxin-mediated LR development.

关键词： ARF7 auxin lateral roots LBD2. MYB108 MYB2

Preparation and Thermal Decomposition of [Cr (salen) (H_2.)_2. Cl

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Chinese Chemical Letters 1999年第5期10卷 429-432页

作者： Bac Xue ZHOU Shu Qin JIANG ding ZHOU Yu Ting ZHAO (Department of Natural Science, Harbin institute of Technology, Weihai Campus, Weihai.{2. 2.42.9)(Department of Chemistry, {2. University. jinan 2.0100) Department of Natural Science Harbin Institute of Technology

A complex of N.N'-ethylencbis (saliylidenemininato) diaquochromium(III) chloride.[Cr (salen) (H2.)2. Cl was prepared. and its decomposition mechanism was studied by TG and DTA. The IR spectrum of the product of thermal decomposition was examined at the first *** results were obtained from the analysis of TG-DTG curves with three different methods The most probable kinetic functions were suggested by comparison of kinetic parameters,

关键词： Chromium(III) complex thermal decomposition. non-isothermal kinetics

Distributed Fault Estimation for Nonlinear Systems With Sensor Saturation and Deception Attacks Using Stochastic Communication Protocols

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IEEE/CAA Journal of Automatica Sinica 2024年第8期11卷 1865-1876页

作者： Weiwei Sun Xinci Gao Lusong ding Xiangyu Chen institute of Automation Qufu Normal UniversityQufu 273165China

This paper is aimed at the distributed fault estimation issue associated with the potential loss of actuator efficiency for a type of discrete-time nonlinear systems with sensor *** the distributed estimation structure under consideration,an estimation center is not necessary,and the estimator derives its information from itself and neighboring nodes,which fuses the state vector and the measurement *** an effort to cut down data conflicts in communication networks,the stochastic communication protocol(SCP)is employed so that the output signals from sensors can be ***,a recursive security estimator scheme is created since attackers randomly inject malicious signals into the selected *** this basis,sufficient conditions for a fault estimator with less conservatism are presented which ensure an upper bound of the estimation error covariance and the mean-square exponential boundedness of the estimating ***,a numerical example is used to show the reliability and effectiveness of the considered distributed estimation algorithm.

关键词： Actuator fault deception attacks distributed estimation sensor saturation stochastic communication protocol(SCP).

On the standard of Penaeus orientalis culture pond building

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Acta Oceanologica Sinica 1993年第2期12卷 299-308页

作者： Li Mingju, Shi ding, Li Mingde,institute of Marine Culture of {2. Province , Qingdao, chinaZhang YongFishery Design institute of {2. Province china

On the basis of the practical experiences and scientific results in the large scale building of Penaeus orientulis culture pond in the past years, this article puts forward for the first time the main principles and designing standard in the culture pond building from the environmental, ecological, social and economic considerations. It probes systematically into main requirements of the designing scale, farm site selection, arrangement of farm site area, engineering of the pond building, pumping station, water supply and drainage canals and electricity supply engineering of the culture pond.

关键词： On the standard of Penaeus orientalis culture pond building 口口