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Echocardiographic Measurements in Normal Chinese Adults (EMINCA) II focusing on left ventricular and left atrial size and function by three-dimensional echocardiography

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FRONTIERS OF MEDICINE 2024年第4期18卷 649-663页

作者： Wang, Yingbin Zhang, Yu Yao, Guihua Tang, Hong Chen, Lixin Yin, Lixue Zhu, Tiangang Yuan, Jianjun Han, Wei Yang, Jun Shu, Xianhong Yang, Ya Wei, Yulin Guo, Yanli Ren, Weidong Gao, Dongmei Lu, Guilin Wu, Ji Yin, Hongning Mu, Yuming Tian, Jiawei Yuan, Lijun Ma, Xiaojing Dai, Hongyan ding, yunchuan ding, Mingyan Zhou, Qing Wang, Hao Xu, Di Zhang, Mei Zhang, Yun Chinese Minist Educ State Key Lab Innovat & Transformat Luobing Theory Jinan 250012 Peoples R China Chinese Minist Educ Chinese Natl Hlth Commiss Key Lab Cardiovasc Remodeling & Funct Res Jinan 250012 Peoples R China Chinese Acad Med Sci Jinan 250012 Peoples R China Shandong Univ Dept Cardiol Qilu Hosp Jinan 250012 Peoples R China Shandong Univ Qingdao Dept Cardiol Qilu Hosp Qingdao 266000 Peoples R China Sichuan Univ West China Hosp Dept Ultrasonog Chengdu 610041 Peoples R China Jinan Univ Shenzhen Peoples Hosp Dept Ultrasonog Clin Med Coll 2 Shenzhen 518020 Peoples R China Elect Sci & Technol Univ China Affiliated Sichuan Prov Peoples Hosp Dept Ultrasonog Chengdu 610072 Peoples R China Peking Univ Dept Cardiol Peoples Hosp Beijing 100044 Peoples R China Henan Prov Peoples Hosp Dept Ultrasonog Zhengzhou 463599 Peoples R China Harbin Med Univ Dept Cardiol Affiliated Hosp 1 Harbin 150007 Peoples R China China Med Univ Dept Echocardiol Affiliated Hosp 1 Shenyang 110001 Peoples R China Fudan Univ Zhongshan Hosp Dept Echocardiol Shanghai 200032 Peoples R China Capital Med Univ Beijing Anzhen Hosp Dept Echocardiol Beijing 100029 Peoples R China Sun Yat Sen Univ Sun Yat Sen Mem Hosp Dept Cardiol Guangzhou 510120 Peoples R China Southwest Hosp AMU Dept Ultrasonog Chongqing 400038 Peoples R China China Med Univ Dept Ultrasonog Shengjing Hosp Shenyang 110136 Peoples R China Jilin Univ Dept Ultrasonog China Japan Union Hosp Changchun 130033 Peoples R China Shihezi Univ Affiliated Hosp 1 Sch Med Dept Ultrasonog Shihezi 832000 Peoples R China Guangxi Med Univ Dept Ultrasonog Affiliated Hosp 1 Nanning 537406 Peoples R China Hebei Med Univ Dept Echocardiol Hosp 2 Shijiazhuang 050061 Peoples R China Xinjiang Med Univ Dept Ultrasonog Affiliated Hosp 1 Urumqi 830054 Peoples R China Harbin Med Univ Dept Ultrasonog Affiliated Hosp 2 Harbin 150088 Peoples R China Air Force Med Univ PLA Dept Ultrasonog Tangdu Hosp Xian 710038 Peoples R China

Current guidelines encourage large studies in a diverse population to establish normal reference ranges for three-dimensional (3D) echocardiography for different ethnic groups. This study was designed to establish the normal values of 3D-left ventricular (LV) and left atrial (LA) volume and function in a nationwide, population-based cohort of healthy Han Chinese adults. A total of 1117 healthy volunteers aged 18-89 years were enrolled from 28 collaborating laboratories in China. Two sets of 3D echocardiographic instruments were used, and full-volume echocardiographic images were recorded and transmitted to a core laboratory for image analysis with a vendor-independent off-line workstation. Finally, 866 volunteers (mean age of 48.4 years, 402 men) were qualified for final analysis. Most parameters exhibited substantial differences between different sex and age groups, even after indexation by body surface area. The normal ranges of 3D-LV and 3D-LA volume and function differed from those recommended by the American Society of Echocardiography and the European Association of Cardiovascular Imaging guidelines, presented by the World Alliance Societies of Echocardiography (WASE) study, and from the 2D values in the EMINCA study. The normal reference values of 3D echocardiography-derived LV and LA volume and function were established for the first time in healthy Han Chinese adults. Normal ranges of 3D-LV and 3D-LA echocardiographic measurements stratified with sex, age, and race should be recommended for clinical applications.

关键词： three-dimensional echocardiography left ventricle left atrium normal reference values Chinese adults NORMAL VALUES EUROPEAN ASSOCIATION AMERICAN SOCIETY REFERENCE RANGES QUANTIFICATION NATIONWIDE CONSENSUS

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Reference values of carotid intima-media thickness and arterial stiffness in Chinese adults based on ultrasound radio frequency signal: A nationwide, multicenter study

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中华医学杂志(英文版) 2024年第15期137卷 1802-1810页

作者： Xing Changyang Xie Xiujing Wu Yu Xu Lei Guan Xiangping Li Fan Zhan Xiaojun Yang Hengli Li Jinsong Zhou Qi Mu Yuming Zhou Qing ding yunchuan Wang Yingli Wang Xiangzhu Zheng Yu Sun Xiaofeng Li Hua Zhang Chaoxue Zhao Cheng Qiu Shaodong Yan Guozhen Yang Hong Mao Yinjuan Zhan Weiwei Ma Chunyan Gu Ying Chen Wu Xie Mingxing Jiang Tianan Yuan Lijun Department of Ultrasound Medicine Tangdu Hospital Air Force Medical University Xi’an Shaanxi China Department of Ultrasound Medicine The First Affiliated Hospital Zhejiang University School of Medicine Hangzhou Zhejiang China Department of Ultrasound Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan Hubei China Department of Ultrasound Xi’an Hospital of Traditional Chinese Medicine Xi’an Shaanxi China Ultrasound Medical Diagnosis Center Shaanxi Provincial People’s Hospital Xi’an Shaanxi China Department of Ultrasound Hospital of Northwestern Polytechnical University Xi’an Shaanxi China Department of Ultrasound Xi’an No. Hospital The First Affiliated Hospital of Northwest University Xi’an Shaanxi China Department of Ultrasound Diagnosis The Second Affiliated Hospital Xi’an Medical College Xi’an Shaanxi China Department of Ultrasound Xi’an Gem Flower ChangQing Hospital Xi’an Shaanxi China Department of Ultrasound The Second Affiliated Hospital of Xi’an Jiaotong University China Xi’an Shaanxi China Department of Echocardiography First Affiliated Hospital of Xinjiang Medical University Urumqi Xinjiang China Department of Ultrasound Renmin Hospital of Wuhan University Wuhan Hubei China Department of Ultrasound Yan’an Hospital The Affiliated Hospital of Kunming Medical University Kunming Yunnan China Department of Ultrasound Yan’an University Xianyang Hospital Xianyang Shaanxi China Department of Function Examination Beijing University of Chinese Medicine Third Affiliated Hospital Beijing China Department of Ultrasound Xi’an Central Hospital Xi’an Shaanxi China Cadre’s Wards Ultrasound Department Diagnostic Ultrasound Center First Hospital of Jilin University Changchun Jilin China Department of Echocardiography Affiliated Hospital of Traditional Chinese Medicine of Xinjiang Medical University Urumqi Xinjiang China Department of Ultrasound First Affiliated Hospital of Anhui Medical University Hefei

Background: Carotid intima-media thickness (IMT) and diameter, stiffness, and wave reflections, are independent and important clinical biomarkers and risk predictors for cardiovascular diseases. The purpose of the present study was to establish nationwide reference values of carotid properties for healthy Chinese adults and to explore potential clinical ***: A total of 3053 healthy Han Chinese adults (1922 women) aged 18-79 years were enrolled at 28 collaborating tertiary centers throughout China between April 2021 and July 2022. The real-time tracking of common carotid artery walls was achieved by the radio frequency (RF) ultrasound system. The IMT, diameter, compliance coefficient, β stiffness, local pulse wave velocity (PWV), local systolic blood pressure, augmented pressure (AP), and augmentation index (AIx) were then automatically measured and reported. Data were stratified by age groups and sex. The relationships between age and carotid property parameters were analyzed by Jonckheere-Terpstra test and simple linear regressions. The major clinical determinants of carotid properties were identified by Pearson’s correlation, multiple linear regression, and analyses of ***: All the parameters of carotid properties demonstrated significantly age-related trajectories. Women showed thinner IMT, smaller carotid diameter, larger AP, and AIx than men. The β stiffness and PWV were significantly higher in men than women before forties, but the differences reversed after that. The increase rate of carotid IMT (5.5 μm/year in women and 5.8 μm/year in men) and diameter (0.03 mm/year in both men and women) were similar between men and women. For the stiffness and wave reflections, women showed significantly larger age-related variations than men as demonstrated by steeper regression slopes (allP for age by sex interaction <0.05). The blood pressures, body mass index (BMI), and triglyceride levels were identified as major clinical determinants o

关键词： Intima-media thickness Arterial stiffness Reference values Ultrasound radio frequency signal Wave reflections

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青少年起病的成人型糖尿病3型家系的药物治疗

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中华糖尿病杂志 2024年第5期16卷 556-560页

作者：谢静丁云川吴胜亮周会杰舒画天津医科大学宝坻临床学院内分泌科天津301800 天津医科大学总医院内分泌代谢科天津300052

报道1例青少年起病的成人型糖尿病3型(MODY3)患者及其家系药物治疗的过程。患者为15岁男性,因“多饮多尿消瘦3个月”入院,依据临床资料和基因检测确诊了1个青少年起病的成人型糖尿病3型(MODY3)家系,并对患者及其家系进行药物治疗。通过... 详细信息

报道1例青少年起病的成人型糖尿病3型(MODY3)患者及其家系药物治疗的过程。患者为15岁男性,因“多饮多尿消瘦3个月”入院,依据临床资料和基因检测确诊了1个青少年起病的成人型糖尿病3型(MODY3)家系,并对患者及其家系进行药物治疗。通过持续葡萄糖监测(CGM)发现患者将胰岛素改为瑞格列奈后血糖明显改善,但需要联合伏格列波糖、西格列汀、德谷胰岛素等药物,而其确诊家系成员应用餐时胰岛素(门冬胰岛素30)治疗,血糖控制达标。在4年随访中,患者血糖控制良好,监测胰岛功能无明显进展,未出现糖尿病并发症。该文通过报道此患者及家系成员的诊疗过程并结合文献复习探讨了MODY3相关治疗药物,以期为类似患者制定更加合理的、个体化的治疗方案提供参考。

关键词：青少年起病的成人型糖尿病3型肝细胞核因子1α 药物治疗

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甲状腺结节与维生素D水平的相关性研究

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首都食品与医药 2024年第2期31卷 11-13页

作者：谢盈慧丁云川梅会静周云霞吴胜亮天津市宝坻区人民医院天津301800

目的研究甲状腺结节与血清维生素D水平的相关性,为寻求甲状腺结节干预方法提供参考依据。方法分析167例体检者临床资料,根据甲状腺超声结果分为结节组(n=68)和对照组(n=99),比较两组生化指标及维生素D缺乏患病率,分析维生素D缺乏与甲状... 详细信息

目的研究甲状腺结节与血清维生素D水平的相关性,为寻求甲状腺结节干预方法提供参考依据。方法分析167例体检者临床资料,根据甲状腺超声结果分为结节组(n=68)和对照组(n=99),比较两组生化指标及维生素D缺乏患病率,分析维生素D缺乏与甲状腺结节发生的相关性。结果与对照组相比,结节组年龄、空腹血糖、糖化血红蛋白高于对照组(P<0.05),血清25羟基维生素D(25-hydroxyvitamin D,25(OH)D)水平低于对照组(P<0.05)。与对照组相比,结节组的高血压病和糖耐量异常患病率更高(P<0.05)。单发结节组与多发结节组相比,血25(OH)D水平差异无统计学意义。超声C-TIRADS分级3类及3类以下组与分级4类及4类以上组相比,血25(OH)D水平差异无统计学意义。二元Logistic回归分析提示年龄≥40岁、维生素D缺乏、糖调节受损为甲状腺结节发生的独立危险因素(P均<0.05)。相对于维生素D正常,维生素D缺乏致甲状腺结节发生风险增加4.931倍(95%CI 1.581-15.727,P=0.001)。结论此研究中甲状腺结节患者血清维生素D水平低于健康人群。维生素D缺乏可能是引起甲状腺结节发生的危险因素。甲状腺结节与维生素D水平的相关性有待进一步研究。

关键词：维生素D 甲状腺结节维生素D缺乏

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腺苷负荷超声心动图联合左室压力-应变环预测经皮冠状动脉介入治疗术后支架内再狭窄程度的临床价值

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临床超声医学杂志 2024年第8期26卷 636-640页

作者：达文会丁云川王庆慧赵丽许彭黎李井池昆明医科大学附属延安医院超声医学科昆明市650051

目的应用腺苷负荷超声心动图(ASE)联合左室压力-应变环(LVPSL)检测经皮冠状动脉介入治疗(PCI)术后支架内再狭窄心肌节段做功参数,探讨其在预测冠状动脉再狭窄程度中的临床应用价值。方法选取我院经冠状动脉造影确诊的PCI术后支架内再狭... 详细信息

目的应用腺苷负荷超声心动图(ASE)联合左室压力-应变环(LVPSL)检测经皮冠状动脉介入治疗(PCI)术后支架内再狭窄心肌节段做功参数,探讨其在预测冠状动脉再狭窄程度中的临床应用价值。方法选取我院经冠状动脉造影确诊的PCI术后支架内再狭窄患者41例,排除腺苷负荷前后图像不满意的12个节段,共获得726个心肌节段,其中狭窄程度75%的节段251个(重度狭窄组),比较各组基础及负荷状态下心肌节段纵向应变(LS)、心肌有用功(CMW)、心肌无用功(WW)、心肌做功指数(MWI)及心肌做功效率(MWE)的差异。绘制受试者工作特征(ROC)曲线分析基础及负荷状态下各心肌做功参数预测PCI术后冠状动脉重度狭窄的诊断效能。结果与无明显狭窄组比较,中度狭窄组基础及负荷状态下LS、MWI、MWE、CMW均减低,WW增加,重度狭窄组基础及负荷状态下LS、MWI、MWE、CMW均减低,负荷状态下WW增加,差异均有统计学意义(均P<0.01);与中度狭窄组比较,重度狭窄组负荷状态下LS、MWI、MWE、CMW均减低,WW增加,差异均有统计学意义(均P<0.01)。与基础状态下比较,无明显狭窄组和中度狭窄组负荷状态下LS、MWI、MWE、CMW均增加,WW减低,差异均有统计学意义(均P<0.05);重度狭窄组负荷状态下LS、MWI、MWE、CMW均减低,WW增加,差异均有统计学意义(均P<0.05)。ROC曲线分析显示,负荷状态下MWI、MWE、CMW预测PCI术后冠状动脉重度狭窄的曲线下面积(AUC)分别为0.829、0.766、0.841,均高于基础状态下各参数的AUC高,且负荷状态下CMW预测PCI术后冠状动脉重度狭窄的AUC高于负荷状态下MWE、WW的AUC,差异均有统计学意义(均P<0.001);负荷状态下CMW与MWI预测PCI术后冠状动脉重度狭窄的AUC比较差异无统计学意义。结论ASE联合LVPSL可有效评估PCI术后再狭窄心肌节段的做功情况,在预测冠状动脉再狭窄程度中有一定的临床应用价值。

关键词：超声心动描记术,腺苷负荷心肌做功经皮冠状动脉介入治疗支架内再狭窄

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腺苷负荷超声联合心肌做功评估慢性冠脉综合征患者节段心肌功能

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中国医药科学 2024年第13期14卷 142-146页

作者：李井池丁云川王庆慧赵丽罗庆祎许彭黎达文会昆明医科大学附属延安医院超声医学科云南昆明650051

目的应用腺苷负荷超声心动图(ASE)联合心肌做功(MW)评估慢性冠脉综合征(CCS)患者腺苷负荷前后节段心肌的功能变化。方法选取2022年1月至2023年1月在昆明医科大学附属延安医院就诊的CCS患者43例,行ASE后均行冠脉造影检查,采用左心室18节... 详细信息

目的应用腺苷负荷超声心动图(ASE)联合心肌做功(MW)评估慢性冠脉综合征(CCS)患者腺苷负荷前后节段心肌的功能变化。方法选取2022年1月至2023年1月在昆明医科大学附属延安医院就诊的CCS患者43例,行ASE后均行冠脉造影检查,采用左心室18节段模型,排除图像不满意的27个节段,将获得的747个心肌节段按照冠脉造影结果分组,狭窄程度0为正常对照组,≤50%为轻度狭窄组、50%75%为重度狭窄组,评估腺苷负荷前后节段心肌的纵向应变及MW参数的变化规律。结果随着冠脉狭窄程度的增加,CCS患者左心室收缩功能会不同程度的受损,MW水平降低。腺苷负荷前后MW参数有明显变化,在冠脉轻、中度狭窄时,腺苷的血管扩张作用使得冠脉的血流灌注有所改善,负荷后的MW水平升高;而重度狭窄时,失去储备功能的狭窄冠脉血流量显著减少,使负荷后MW水平明显降低。预测冠脉重度狭窄发生以负荷心肌有用功诊断价值最高,优于其他做功参数。结论结合ASE检查和MW参数的评估,可以对CCS患者的节段心肌功能进行定量分析。通过比较节段心肌在基础、负荷状态下的差异来预估患者的左心室功能,为临床诊断和治疗提供帮助。

关键词：心肌做功心室功能慢性冠脉综合征腺苷负荷超声心动图

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Measurement of left ventricular fluid dynamic parameters in healthy Chinese adults based on echocardiographic vector flow mapping

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Chinese Medical Journal 2023年第5期136卷 616-618页

作者： Sijia Wang Lixue Yin Anguo Luo Zhengyang Wang Shan Wang Geqi ding Xiuzhang Lyu Yunyou Duan Qing Zhou Mei Zhang Di Xu Jiawei Tian Hong Tang Guang Zhi yunchuan ding Xianhong Shu Mingxing Xie Ying Yang Jun Zhang Tiangang Zhu Yuhong Feng Ultrasound in Cardiac Electrophysiology and Biomechanics Key Laboratory of Sichuan Province Sichuan Provincial People’s HospitalUniversity of Electronic Science and Technology of ChinaChengduSichuan 610072China Department of Cardiology Beijing Chaoyang HospitalCapital Medical UniversityBeijing 100020China Department of Ultrasound Diagnostics Tangdu HospitalAir Force Medical UniversityXi’anShaanxi 710032China Department of Ultrasonography Renmin Hospital of Wuhan UniversityWuhanHubei 430060China The Key Laboratory of Cardiovascular Remodeling and Function Research Chinese Ministry of EducationChinese National Health Commission and Chinese Academy of Medical SciencesThe State and Shandong Province Joint Key Laboratory of Translational Cardiovascular MedicineDepartment of CardiologyQilu Hospital of Shandong UniversityJinanShandong 250012China Department of Ultrasound The First Affiliated Hospital with Nanjing Medical UniversityNanjingJiangsu 210029China Department of Ultrasound The Second Affiliated Hospital of Harbin Medical UniversityHarbinHeilongjiang 150086China Department of Cardiology West China HospitalSichuan UniversityChengduSichuan 610041China Department of Cardiology Chinese PLA General HospitalChinese PLA Medical SchoolBeijing 100080China Department of Ultrasound Yan’an Hospital of Kunming Medical UniversityKunmingYunnan 650051China Division of Echocardiography and the Division of Cardiology Zhongshan Hospital of Fudan UniversityShanghai 200032China Department of Ultrasound Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei 430022China Department of Cardiovascular Disease Peking University First HospitalBeijing 100034China Xijing Hypertrophic Cardiomyopathy Center Department of UltrasoundXijing HospitalAir Force Medical UniversityXi’anShaanxi 710032China Department of Cardiology Beijing Key Laboratory of Early Prediction and Intervention of Acute Myocardial InfarctionCenter for Cardiovascular Translational Resear

To the Editor:As we concerdered that there was barely any widely representative,recognized,and standardized echocardiographic vector flow mapping(VFM)method has been established for the observation and measurement of the blood flow in cardiac cavities in clinical practice,and there were no commonly accepted normal reference values for Chinese adults have been obtained till now,hindering the further promotion and application of this technology in clinical *** normal reference values for echocardiographic VFM that can be widely accepted in clinical practice is of great significance for determining the normal or abnormal fluid dynamic status in the left ventricle(LV)chamber.

关键词： flow mapping dynamic

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Rainfall-triggered waste dump instability analysis based on surface 3D deformation in physical model test

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Journal of Mountain Science 2024年第5期21卷 1549-1563页

作者： LI Hanlin JIN Xiaoguang HE Jie XUE yunchuan YANG Zhongping School of Civil Engineering Chongqing UniversityChongqing 400038China

Landslide is the second largest natural disaster after earthquake. It is of significance to study the evolution laws and failure mechanism of landslides based on its surface 3D deformation information. Based on the rainfall-triggered waste dump instability model test, we studied the failure mechanisms of the waste dump by integrating surface deformation and internal slope stress and proposed novel parameters for identifying landslide stability. We developed a noncontact measurement device, which can obtain millimeter-level 3D deformation data for surface scene in physical model test;Then we developed the similar materials and established a test model for a waste dump. Based on the failure characteristics of slope surface, internal stress of slope body and displacement contours during the whole process, we divided the slope instability process in model test into four stages: rainfall infiltration and surface erosion, shallow sliding, deep sliding, and overall instability. Based on the obtained surface deformation data, we calculated the volume change during slope instability process and compared it with the point displacement on slope surface. The results showed that the volume change can not only reflect the slow-ultra acceleration process of slope failure, but also fully reflect the above four stages and reduce the fluctuations caused by random factors. Finally, this paper proposed two stability identification parameters: the volume change rate above the slip surface and the relative velocity of volume change rate. According to the calculation of these two parameters in model test, they can be used for study the deformation and failure mechanism of slope stability.

关键词： Waste dump stability Physical model test Surface 3D deformation Stability identification

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Natural vibration and critical velocity of translating Timoshenko beam with non-homogeneous boundaries

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Applied Mathematics and Mechanics(English Edition) 2024年第9期45卷 1523-1538页

作者： Yanan LI Jieyu ding Hu ding Liqun CHEN Shanghai Institute of Applied Mathematics and Mechanics Shanghai Key Laboratory of Mechanics in Energy EngineeringShanghai Frontier Science Center of MechanoinformaticsSchool of Mechanics and Engineering ScienceShanghai UniversityShanghai 200072China School of Mathematics and Statistics Qingdao UniversityQingdao 266071Shandong ProvinceChina

In most practical engineering applications,the translating belt wraps around two fixed *** boundary conditions of the dynamic model are typically specified as simply supported or fixed *** this paper,non-homogeneous boundaries are introduced by the support *** the translating belt as the mechanical prototype,the vibration characteristics of translating Timoshenko beam models with nonhomogeneous boundaries are investigated for the first *** governing equations of Timoshenko beam are deduced by employing the generalized Hamilton's *** effects of parameters such as the radius of wheel and the length of belt on vibration characteristics including the equilibrium deformations,critical velocities,natural frequencies,and modes,are numerically calculated and *** numerical results indicate that the beam experiences deformation characterized by varying curvatures near the *** radii of the wheels play a pivotal role in determining the change in trend of the relative difference between two beam *** the results unearths that the relative difference in equilibrium deformations between the two beam models is more pronounced with smaller-sized *** the two wheels are of equal size,the critical velocities of both beam models reach their respective *** addition,the relative difference in natural frequencies between the two beam models exhibits nonlinear variation and can easily exceed 50%.Furthermore,as the axial velocities increase,the impact of non-homogeneous boundaries on modal shape of translating beam becomes more *** dealing with non-homogeneous boundaries is challenging,beam models with non-homogeneous boundaries are more sensitive to parameters,and the differences between the two types of beams undergo some interesting variations under the influence of non-homogeneous boundaries.

关键词： translating beam Timoshenko beam non-homogeneous boundary natural frequency critical velocity

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Whittle’s Index Based Sensor Scheduling for Multiprocess Systems Under DoS Attacks

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Journal of Systems Science & Complexity 2024年第1期37卷 329-350页

作者： CAI Zai ding Kemi Shenzhen Key Laboratory of Control Theory and Intelligent Systems Southern University of Science and TechnologyShenzhen 518055China.

In this paper,the authors consider how to design defensive countermeasures against DoS attacks for remote state estimation of multiprocess *** each system,a sensor will measure its state and transmits the data packets through an unreliable channel which is vulnerable to be jammed by an *** limited communication bandwidth,only a subset of sensors are allowed for data transmission,and how to select the optimal one to maximize the accuracy of remote state estimation is the focus of the proposed *** authors first formulate this problem as a Markov decision process and investigate the existence of optimal ***,the authors demonstrate the piecewise monotonicity structure of optimal *** the difficulty of obtaining an optimal policy of large-scale problems,the authors develop a suboptimal heuristic policy based on the aforementioned policy structure and Whittle’s ***,a closed form of the indices is derived in order to reduce implementation complexity of proposed scheduling policy and numerical examples are provided to illustrate the proposed developed results.

关键词： DoS attacks Kalman filter remote state estimation Whittle’s index.

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