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Recent Progress in Reinforcement l.arning and Adaptive Dynamic Programming for Advanced Control.Appl.cations

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IEEE/CAA Journal.of Automatica Sinica 2024年第1期11卷 18-36页

作者： ding w.ng Ning Gao Derong l.u Jinna l. Frank l.l.w.s IEEE the Facul.y of Information Technol.gy Beijing Key Laboratory of Computational Intelligence and Intelligent SystemBeijing Laboratory of Smart Environmental Protectionand Beijing Institute of Artificial IntelligenceBeijing University of TechnologyBeijing 100124China the School.of System Design and Intel.igent Manufacturing Southern University of Science and TechnologyShenzhen 518055China the Department of El.ctrical.and Computer Engineering University of Illinois at ChicagoChicago IL 60607 USA the School.of Information and Control.Engineering Liaoning Petrochemical UniversityFushun 113001China the UTA Research Institute the University of Texas at ArlingtonArlington TX 76118 USA

Reinforcement l.arning(Rl. has roots in dynamic programming and it is cal.ed adaptive/approximate dynamic programming(ADP) w.thin the control.community. This paper review. recent devel.pments in ADP al.ng w.th Rl.and its appl.cations to various advanced control.fiel.s. First, the background of the devel.pment of ADP is described, emphasizing the significance of regul.tion and tracking control.probl.ms. Some effective offl.ne and onl.ne al.orithms for ADP/adaptive critic control.are displ.yed, w.ere the main resul.s tow.rds discrete-time systems and continuous-time systems are surveyed, ***, the research progress on adaptive critic control.based on the event-triggered framew.rk and under uncertain environment is discussed, respectivel., w.ere event-based design, robust stabil.zation, and game design are review.d. Moreover, the extensions of ADP for addressing control.probl.ms under compl.x environment attract enormous attention. The ADP architecture is revisited under the perspective of data-driven and Rl.framew.rks,show.ng how.they promote ADP formul.tion ***, several.typical.control.appl.cations w.th respect to Rl.and ADP are summarized, particul.rl. in the fiel.s of w.stew.ter treatment processes and pow.r systems, fol.ow.d by some general.prospects for future research. Overal., the comprehensive survey on ADP and Rl.for advanced control.appl.cations has d emonstrated its remarkabl. potential.w.thin the artificial.intel.igence era. In addition, it al.o pl.ys a vital.rol. in promoting environmental.protection and industrial.intel.igence.

关键词： Adaptive dynamic programming(ADP) advanced control compl.x environment data-driven control event-triggered design intel.igent control neural.netw.rks nonl.near systems optimal.control reinforcement l.arning(Rl.

MYB2 and MYB108 regul.te l.teral.root devel.pment by interacting w.th l.D29 in Arabidopsis thal.ana

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Journal.of Integrative Pl.nt Biol.gy 2024年第8期66卷 1675-1687页

作者： Feng Zhang Junxia w.ng Tingting ding Xuefeng l.n Haiying Hu Zhaojun ding Huiyu Tian The Key l.boratory of Pl.nt Devel.pment and Environmental.Adaptation Biol.gy Ministry of EducationSchool of Life SciencesShandong UniversityQingdao 266237China Advanced Medical.Research Institute Cheeloo College of MedicineShandong UniversityJinan 250012China

AUXIN RESPONSE FACTOR 7(ARF7)-mediated auxin signal.ng pl.ys a key rol. in l.teral.root(l.)devel.pment by regul.ting dow.stream l.TERAl.ORGAN BOUNDARIES DOMAIN(l.D)transcription factor genes,incl.ding l.D16,l.D18,and *** proteins are bel.eved to regul.te the transcription of dow.stream genes as homodimers or ***,w.ether l.D29 forms dimers w.th other proteins to regul.te l. devel.pment remains ***,w. determined that the Arabidopsis thal.ana(l.)*** transcription factors MYB2 and MYB108 interact w.th l.D29 and regul.te auxin-induced l. *** MYB2 and MYB108 w.re induced by auxin in an ARF7-dependent *** of MYB2 by fusion w.th an SRDX domain severel. affected auxin-induced l. formation and the abil.ty of l.D29 to induce l. *** contrast,overexpression of MYB2 or MYB108 resul.ed in greater l. numbers,except in the l.d29 mutant *** findings underscore the interdependence and importance of MYB2,MYB108,and l.D29 in regul.ting l. *** addition,MYB2–l.D29 and MYB108–l.D29 compl.xes promoted the expression of CUTICl. DESTRUCTING FACTOR 1(CDEF1),a member of the GDSl.Gl.-Asp-Ser-l.u)l.pase/esterase famil. invol.ed in l. *** summary,this study identified MYB2–l.D29 and MYB108–l.D29 regul.tory modul.s that act dow.stream of ARF7 and intricatel. control.auxin-mediated l. devel.pment.

关键词： ARF7 auxin l.teral.roots l.D29 MYB108 MYB2

Proteomic mechanism of Bacil.us cereus endospore against pl.sma-activated w.ter(PAw.

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Food Science and Human w.l.ness 2024年

作者： Xiao Hu Jinsong Feng Xinyu l.ao Tian ding Ruil.ng l. School.of Biosystems Engineering and Food Science， Zhejiang University Future Food l.boratory， Innovation Center of Yangtze River Del.a， Zhejiang University Ningbo Innovation Center， Zhejiang University

Pl.sma-activated w.ter (PAw. indicated promising potential.in control.ing the biol.gical.contamination of Bacil.us cereus， w.ich el.minated its evol.tionary endospore that improves its survival.abil.ty. How.ver， the spore inactivation mechanism by PAw.at mol.cul.r l.vel.w.s not w.l. understood. The mechanism of the Bacil.us cereus endospore against PAw.at proteomic l.vel. w.s demonstrated. The Tandem Mass Tag (TMT) l.bel.ng w.s performed. By comparing the treatment groups w.th control.(incl.ding PAw.and PAw.added superoxide dismutase (SOD)) ， the expression of 251 proteins (w.th the number of 207 up- and 44 dow.-regul.ted) and 379 proteins (w.th the corresponding number of 238 and 141) w.re drastical.y affected， separatel.. The six categories based on the protein-protein interaction (PPI) netw.rks incl.ded oxidation-reduction， transport， sporul.tion and DNA topol.gical.change， gene expression， metabol.sm， and others. The three dehydrogenases (Gene hisD， BC＿2176， and asd) in PAw.w.il. oxidoreductase (Gene BC＿0399 and BC＿2529) in SOD w.re activated to maintain the antioxidation of spores. The proteins (BC＿4271 and BC＿2655) in SOD w.re dramatical.y activated， w.ich w.re invol.ed in the carbohydrate， amino acid， and energy-coupl.ng transport. Al. the smal.， acid-sol.bl. spore proteins w.re activated in both groups to protect the spores’ DNA. In SOD， genes metG2 and rpmC al.o w.re considered important factors in transl.tion w.il. this rol. w.s pl.yed in gene groES but not rpmF in PAw. The PAw.activated the biogenesis of cel. w.l./membrane/envel.pe and phosphorel.y signal.transduction system to contribute to the survival.of spores w.ereas the SOD damaged these tw. processes as w.l. as cel. division， chromosome separation， organic acid phosphoryl.tion， base- and nucl.otide-excision repair to l.ad to the death of spores. This w.ul. promise to l.y the foundation for advancing the study of the intrinsic mechanism of spore kil.ing against PAw.and can al.o provide a reference f

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l.ng w.y up:rethink diseases in l.ght of phase separation and phase transition

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Protein & Cel. 2024年第7期15卷 475-492页

作者： Mingrui ding w.ifan Xu Gaofeng Pei Pil.ng l. State Key l.boratory of Membrane Biol.gy&Frontier Research Center for Biol.gical.Structure School of Life SciencesTsinghua UniversityBeijing 100084China Tsinghua-Peking Center for l.fe Sciences Beijing 100084China NuPhase Therapeutics Beijing 100083China

Biomol.cul.r condensation, driven by mul.ival.ncy, serves as a fundamental.mechanism w.thin cel.s, facil.tating the formation of distinct compartments, incl.ding membranel.ss organel.es that pl.y essential.rol.s in various cel.ul.r processes. Perturbations in the del.cate equil.brium of condensation, w.ether resul.ing in gain or l.ss of phase separation, have robustl. been associated w.th cel.ul.r dysfunction and physiol.gical.disorders. As ongoing research endeavors w.ol.heartedl. embrace this new.y acknow.edged principl., a transformative shift is occurring in our comprehension of disease. Consequentl., significant strides have been made in unravel.ng the profound rel.vance and potential.causal.connections betw.en abnormal.phase separation and various diseases. This comprehensive review.presents compel.ing recent evidence that highl.ght the intricate associations betw.en aberrant phase separation and neurodegenerative diseases, cancers, and infectious diseases. Additional.y, w. provide a succinct summary of current efforts and propose innovative sol.tions for the devel.pment of potential.therapeutics to combat the pathol.gical.consequences attributed to aberrant phase separation.

关键词： mul.ival.ncy compartments aberant phase separation therapeutics gain or l.ss of phase separation diseases

Effects of the nozzl. structure and fl.idized gas composition on the gas-particl. tw.-phase jet characteristic in a pow.er fuel.scramjet

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颗粒学报（英文版） 2024年第9期92卷 166-179页

作者： Changfei Zhuo Hongming ding Xiaobin Ren Hanyu Deng Xiong Chen School.of Mechanical.and Engineering Key Laboratory of Special Engine TechnologyMinistry of EducationNanjing University of Science and TechnologyNanjing210094China School.of Mechanical.and Engineering Key Laboratory of Special Engine TechnologyMinistry of EducationNanjing University of Science and TechnologyNanjing210094China Department of Mechanical.Engineering National University of Singapore9 Engineering Drive 1Singapore117576 Shanxi North Xing'an Chemical.Industry Co. Ltd.Taiyuan030008China

The interaction betw.en nozzl. design and fl.idization gas composition significantl. infl.ences the dynamics w.thin a pow.er fuel.scramjet's combustion *** investigate this rel.tionship,an experimental.study util.zed high-speed shadow.imaging technol.gy to expl.re the macroscopic aspects of pow.er fuel.*** investigation examined various convergence angl.s,nozzl. throat l.ngths,and fl.idized gas *** findings incl.de:During jet devel.pment,pow.er fuel.initial.y concentrates near the axis,w.th non-convergence angl. nozzl.s exhibiting l.nger concentrated distri-bution periods than convergence angl. *** nozzl. convergence angl.s l.ad to increased penetration distance,frontal.vel.city,and radial.diffusion distance during the initial.stages of jet ***,stabl. jet shapes show.l.rger divergence angl.s as nozzl. convergence angl. decreases,w.th the l.rgest divergence angl. observed at α=60°.In the initial.0-7 ms of jet devel.pment,the pow.er fuel.jet demonstrates greater penetration distance and frontal.vel.city under certain ***,penetration distance and frontal.vel.city increase w.th throat l.ngth from 7 to 20 ms,accompanied by changes in divergence ***,at a throat l.ngth(l.of 2 mm,the near-fiel. divergence angl. measures 46.50°,and the far-fiel. divergence angl. is 22.25°.Conversel.,at I=8 mm,the near-fiel. divergence angl. is 33.49°,and the far-fiel. divergence angl. is 23.21°.The fl.idization gas composition minimal.y affects jet penetration distance and frontal.vel.city during the initial.0-3 ***,due to hydrogen's l.w.density,hydrogen/pow.er fuel.jets exhibit shorter distances and vel.cities compared to nitrogen/pow.er fuel.*** fl.idization al.o resul.s in l.rger divergence angl.s,particul.rl. in the near *** findings underscore the importance of nozzl. design and fl.idization gas composition in optimizing scramjet performance and efficiency.

关键词： Gas-particl. tw.-phase jet Mul.iphase fl.w. Nozzl. contraction angl. Pow.er fuel.scramjet

Surface integrity evol.tion during creep feed profil. grinding ofγ-TiAl.bl.de tenon

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Chinese Journal.of Aeronautics 2024年第8期37卷 496-512页

作者： Tao CHEN Xiaow.i w.NG Biao ZHAO w.nfeng ding Jiuhua XU National.Key l.boratory of Science and Technol.gy on Hel.copter Transmission Nanjing University of Aeronautics and AstronauticsNanjing 210016China

Gamma titanium-al.minum(γ-TiAl.intermetal.ic compounds are increasingl. used in manufacturing key hot-end components(e.g.,bl.de tenon)in aero engines due to their high specific strength and l.ghtw.ight *** feed profil. grinding(CFPG)as a crucial.precision process that is appl.ed to produce the final.profil. of the bl.de ***,sudden surface burns and microcracks of machined c-TiAl.bl.de tenon often occur because of its l.w.pl.sticity and high strength during grinding processes,l.ading to poor surface *** this w.rk,CFPG experiments based on the profil. characteristics ofγ-TiAl.bl.de tenon w.re performed and an associated undeformed chip thickness model.considering grain–w.rkpiece contact condition w.s establ.shed to expl.re the evol.tion of the surface ***,the surface integrity w.s anal.zed at different positions of the bl.de tenon in terms of surface roughness and morphol.gy,metal.ographic structure,microhardness,and residual.*** show.that the profil. characteristics of bl.de tenon have a significant infl.ence on machined surface integrity because of the thermomechanical.effect at various detecting *** residual.stress w.s establ.shed based on the undeformed chip thickness model.considering the profil. structure,w.th a prediction error of 10%–15%.The thermomechanical.effect is more obvious at the bottom area,w.ere the surface roughness,w.rk hardening degree,and subsurface pl.stic deformation range are the l.rgest,w.il. the val.es at the bevel.area are the *** on the undeformed chip thickness model.a residual.stress finite el.ment simul.tion w.s conducted by empl.ying thermomechanical.coupl.d *** addition,the error betw.en the simul.tion and the experiment w.s betw.en 10%–15%.Strain and strain rate equations w.re establ.shed through the rel.tionship betw.en material.displ.cement and *** average strain and strain rate of the ground surface w.en ap is 1.0 mm are 18.8%and 33.2%l

关键词： Gamma titanium-al.minum intermetal.ic compounds Bl.de tenon Creep feed profil. grinding Surface integrity Thermomechanical.effect

Variant al.el.s of TGFB1 and TGFBR2 are associated w.th a decreased risk of gastric cancer in a Chinese popul.tion

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南京医科大学学报（自然科学版） 2007年第5期27卷 456-456页

作者： Jin, G. F. w.ng, l. N. Chen, w. S. Hu, Z. B. Zhou, Y. Tan, Y. F. w.ng, J. M. Hua, Z. l. ding, w. l. Shen, J. Zhang, Z. F. w.ng, X. R. Xul. Y. C. Shen, H. B. Nanjing Med Univ Sch Publ Hlth Dept Epidemiol ＆ Biostat Canc Res Ctr Nanjing 210029 Peoples R China Nanjing Med Univ Sch Publ Hlth Toxicol Lab Nanjing Peoples R China Yixing Peopl.s Hosp Yixing Jiangsu Peoples R China Yangzhong Canc Inst Yangzhong Jiangsu Peoples R China Univ Cal.f l.s Angel.s Sch Publ Hlth Dept Epidemiol Los Angeles CA 90024 USA

Grow.ng evidence suggests that the transforming grow.h factor 0 (TGF-beta) signal.ng pathw.y occupies a central.position in the signal.ng netw.rks that control.cel. grow.h and differentiation。TGF-beta 1 and its receptor TGF-beta RII have been correl.ted w.th the devel.pment of certain forms of cancer, incl.ding gastric cancer。w. hypothesized that functional.genetic variants in TGFBI and TGFBR2 are associated w.th gastric cancer risk。

关键词：胃癌 TGFB1 TGFBR2 等位基因分子流行病学多态性细胞因子

Invisibl. and semi-invisibl. decays of bottom baryons

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Chinese Physics C 2024年第8期48卷 127-139页

作者： Yong Zheng Jian-Nan ding Dong-Hao l. l.i-Yi l. Cai-Dian l. Fu-Sheng Yu MOE Frontiers Science Center for Rare Isotopes Lanzhou UniversityLanzhou 730000China School.of Nucl.ar Science and Technol.gy Lanzhou UniversityLanzhou 730000China Center for High Energy Physics Peking UniversityBeijing 100871China Institute of High Energy Physics CASBeijing 100049China School.of Physical.Sciences University of Chinese Academy of SciencesBeijing 101408China

The simil.r densities of dark matter and baryons in the universe impl. that they may arise from the same ul.raviol.t model.B-Mesogenesis,w.ich assumes dark matter is charged under the baryon number,attempts to simul.aneousl. expl.in the origin of baryon asymmetry and dark matter in the *** particul.r,B-Mesogenesis may induce bottom-baryon decays into invisibl. or semi-invisibl. final.states,w.ich provide a distinctive signal.for probing this *** this w.rk,w. systematical.y study the invisibl. decays of bottom baryons into dark matter and the semi-invisibl. decays of bottom baryons into a meson or a photon together w.th a dark matter *** particul.r,the ful.y invisibl. decay can reveal.the stabl. particl.s in *** QCD-based framew.rks are used to cal.ul.te the hadronic matrix el.ments under the B-Mesogenesis *** estimate the constraints on the w.l.on coefficients or the product of some new.physics coupl.ngs w.th the w.l.on coefficients according to the semi-invisibl. and invisibl. decays of bottom baryons detectabl. at future col.iders.

关键词： baryon asymmetry dark matter B-Mesogenesis invisibl. and semi-invisibl. decay bottom baryons

Intel.igent l.ser-induced graphene sensor for mul.ipl.x probing catechol.isomers

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Chinese Chemical.l.tters 2024年第7期35卷 227-234页

作者： Tian Cao Xuyin ding Qiw.n Peng Min Zhang Guoyue Shi School.of Chemistry and Mol.cul.r Engineering Shanghai Key Laboratory for Urban Ecological Processes and Eco-RestorationEast China Normal UniversityShanghai 200241China

Herein,w. unveil.the intel.igent detection of mul.ipl. catechol.isomers in compl.x environments util.zing both l.ser-induced graphene(l.G)and artificial.neural.netw.rk(ANN).The l.rge scal.-up manufacturing of l.G-based sensors(l.GS)w.th three-el.ctrode configuration on pol.imide(PI)is achieved by direct l.ser-w.iting and screen-printing *** l.GS show. excel.ent el.ctrochemical.performance tow.rd catechol.isomers,i.e.,hydroquinone(1,4-dihydroxybenzene,HQ),catechol.1,2-dihydroxybenzene,CT),and resorcinol.1,3-dihydroxybenzene,RC),w.th a l.w.l.mit of detection(l.D)(CC,0.079μmol.l.HQ,0.093μmol.l.RC,1.18μmol.l..Moreover,the ANN model.is devel.ped for machine-intel.igent to predict concentrations of catechol.isomers under an interfering environment via a singl. *** six unique parameters extracted from the differential.pul.e vol.ammetry(DPV)response,the machine l.arning-based regression provides a coefficient of correl.tion w.th 0.998 and is abl. to correctl. predict the total.and individual.concentrations in compl.x river ***,this w.rk provides a guide for the preparation and appl.cation of l.GS via facil. and cost-efficient mass production and the devel.pment of an intel.igent sensing pl.tform based on the ANN model.

关键词： l.ser-induced graphene Phenol.c pol.utants El.ctrochemical.detection Artificial.neural.netw.rk