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Non-unique Probe Selection with Group Testing

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Non-unique Probe Selection with Group Testing

Original article：A novel two-stage complete repair method for pulmonary atresia with ventricular septal defect and major aortopulmonary collateral arteries

第一届最优化与系统生物学国际研讨会

作者： Ping Deng Feng Wang ding-zhu Du Department of Computer Science University of Texas at Dallas Department of Computer Science University of Minnesota School of Science Xi'an Jiaotong University

Non-unique probe selection is an important research problem in computational molecular biology. One of approaches to study it is group testing. A minization problem arosen from such study is as follows: Give a binary matrix, find a d-disjunct submatrix with the minimum number of rows and the same number of columns. We give a mini survey on its computational complexityshow and approximation algorithms.

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Chinese Medical Journal 2010年第3期 259-264页

作者： MEI Ju ding Fang-bao zhu Jia-quan BAO Chun-rong XIE Xiao ZHANG Yun-jiao Department of Cardiothoracic Surgery Xinhua Hospital Shanghai Jiao Tong University School of Medicine Shanghai 200092 China

Background Pulmonary atresia with ventricular septal defect （PA-VSD） and major aortopulmonary collateral arteries （MAPCAs） remains a challenging complex congenital heart disease nowadays. In the present study, we aimed to develop a two-stage surgical method and to evaluate outcomes of this method in managing PA-VSD and MAPCAs. Methods Between December 2003 and December 2008, 7 female and 4 male patients between the age of 5 and 10 years who were suffering from PA-VSD and MAPCAs were selected and recruited. The native pulmonary artery trunks were absent in all patients; the lungs were solely supplied by major aortopulmonary collaterals, and the numbers of supplied lung segments ranged from 15 to 20 （17.9±1.6）. There were a total of 43 MAPCAs in all the patients （3-5 （3.9~0.7） MAPCAs per patient）. The accumulated Nakata index was （222.9＋_29.9） mm2/m2 （ranged from 182 to 272）. All the patients underwent two sequential operations. Stage one included left major aortopulmonary collateral unifocalization and modified Blalock-Taussig shunt from left posterior lateral thoracotomy; stage two comprised right unifocalization, ligation of the shunt, followed by ventricular septal defect closure and right ventricular outflow tract reconstruction assisted with cardiopulmonary bypass from midline sternotomy. Results All the patients survived the initial surgery, but one of them died of low cardiac output syndrome on the third day after the second operation. Postoperative complications included pneumonia in one case and capillary leak syndrome in another. Postoperative oxygen saturation maintained about 95%-100%, which was significantly higher than pre-operation （P 〈0.01）. During the follow-up period of 3-51 （25.4±15.2） months, there were no late death and no need for reintervention. All the patients enjoyed their lives with good conditions. Conclusions This two-stage complete repair strategy was well-tolerated and effective with good outcome, thus offering an alternative surgical a

关键词： pulmonary atresia major aortopulmonary collateral arteries unifocalization surgery congenital heart disease

A CASE STUDY OF THE UNCORRELATED RELATIONSHIP BETWEEN TROPICAL TROPOPAUSE TEMPERATURE ANOMALIES AND STRATOSPHERIC WATER VAPOR ANOMALIES

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Journal of Tropical Meteorology 2018年第3期24卷 356-368页

作者： HAN Yuan-yuan TIAN Wen-shou ZHANG Jian-kai HU ding-zhu WANG Fei-yang SANG Wen-jun Key Laboratory for Semi-Arid Climate Change of the Ministry of Education College of Atmospheric SciencesLanzhou UniversityLanzhou 730000 China College of Environmental and Chemical Engineering Xi'an Polytechnic UniversityXi'an 710048 China Key Laboratory of Meteorological Disasters of China Ministry of Education/Joint International Research Laboratory of Climate and Environment Change/Collaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters Nanjing University of Information Science&TechnologyNanjing 210044 China

Using the measurements from the Halogen Occultation Experiment(HALOE)and the European Centre for Medium-Range Weather Forecasts(ECMWF)Interim reanalysis data for the period 1994-2005,we analyzed the relationship between tropical tropopause temperature anomalies and stratospheric water vapor *** is found that tropical tropopause temperature is correlated with stratospheric water vapor,i.e.,an anomalously high(low)tropical tropopause temperature corresponds to anomalously high(low)stratospheric water vapor during the period 1994-2005,except for *** occurrence frequency and strength of deep convective activity during the‘mismatched'months is less and weaker than that during the‘matched'months in ***,the instantaneous intensity of four short periods of deep convective activity,caused by strong surface cyclones and high sea surface temperatures,are greater during the‘mismatched'months than during the‘matched'*** vapor is transported from the lower troposphere to the lower stratosphere through a strong tropical upwelling,leading to an increase in stratospheric water *** the other hand,deep convective activity can lift the tropopause and cool its *** short,the key factor responsible for the poor correlation between tropical tropopause temperature and stratospheric water vapor in1996 is the instantaneous strong deep convective *** addition,an anomalously strong Brewer-Dobson circulation brings more water vapor into the stratosphere during the‘mismatched'months in 1996,and this exacerbates the poor correlation between tropical tropopause temperature and stratospheric water vapor.

关键词： tropical tropopause temperature stratospheric water vapor deep convective activity Brewer-Dobson circulation ENSO

应重视在高血压患者中开展原发性醛固酮增多症的筛查、确诊和分型定位检查

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中华心血管病杂志 2006年第10期34卷 865-867页

作者：朱鼎良上海交通大学医学院瑞金医院高血压科200025

自1955年Conn等报道首例原发性醛固酮增多症（简称原醛）患者以后的30多年中，原醛一直被认为是一种少见疾病，在高血压人群中原醛患病率不到1％。1981年Hiramatsu等首次采用血浆醛固酮／血浆肾素活性比值（ARR）作为原醛筛查指标，在34... 详细信息

自1955年Conn等报道首例原发性醛固酮增多症（简称原醛）患者以后的30多年中，原醛一直被认为是一种少见疾病，在高血压人群中原醛患病率不到1％。1981年Hiramatsu等首次采用血浆醛固酮／血浆肾素活性比值（ARR）作为原醛筛查指标，在348例未经选择的高血压患者中发现9例（2．6％）醛固酮腺瘤（APA）患者。从20世纪90年代起，国外普遍采用ARR作为原醛筛查指标，目前达成以下共识：原醛不是少见病，多数报道原醛占高血压患者的5％-15％。低血钾不是原醛必须具备的特征，在确诊的原醛患者中，低血钾发生率仅为9％-37％。澳大利亚Princess Alexandra医院高血压科自1991年起对所有高血压就诊患者进行ARR测定，使原醛的检出率提高了10倍，肾上腺腺瘤手术数增加了4倍。

关键词：原发性醛固酮增多症高血压患者筛查指标定位检查确诊分型高血压人群血浆醛固酮

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我国高血压基因研究十年回顾和几点建议

中华心血管病杂志 2005年第7期33卷 585-587页

作者：朱鼎良上海第二医科大学附属瑞金医院高血压科上海市高血压研究所 200025

20世纪90年代初起,高血压发病机理研究深入到基因水平.我国高血压基因研究起步于20世纪90年代中期.本文对近10年来我国高血压基因研究作简要回顾,并对今后研究策略提出几点粗浅意见。

关键词：基因研究高血压 20世纪90年代基因水平机理研究研究策略

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压裂液屈服应力实验研究

油田化学 2010年第4期27卷 420-422页

作者：王雷朱丁石油工程教育部重点实验室(中国石油大学) 北京102249 德克萨斯A&M大学石油工程系德克萨斯77843

压裂施工过程中裂缝内浓缩的压裂液具有较高的屈服应力,会导致压裂液返排效率低,有效缝长短。实验原理基于虎克定律,压裂液屈服前的应力与应变为线性关系;当其偏离线性关系时,压裂液屈服。采用自制实验装置考察了瓜尔胶与破胶剂浓度对... 详细信息

压裂施工过程中裂缝内浓缩的压裂液具有较高的屈服应力,会导致压裂液返排效率低,有效缝长短。实验原理基于虎克定律,压裂液屈服前的应力与应变为线性关系;当其偏离线性关系时,压裂液屈服。采用自制实验装置考察了瓜尔胶与破胶剂浓度对压裂液屈服应力的影响。实验结果表明,瓜尔胶浓度较低时,压裂液屈服应力较小,瓜尔胶浓度4.8g/L时的屈服应力仅为0.329Pa;随着瓜尔胶浓度的增加,压裂液屈服应力迅速增大,瓜尔胶浓度为24g/L时,屈服应力增至63.292Pa。在压裂液中加入破胶剂可以有效减小压裂液的屈服应力。压裂液屈服应力为0时,瓜尔胶浓度与所需破胶剂量的关系近似为线性关系,瓜尔胶浓度越高所需破胶剂量越大。

关键词：水力压裂压裂液屈服应力瓜尔胶破胶剂

Water-requirement Characteristics and Water-saving Irrigation Indices of Dry-raised Rice Seedlings in Paddy Field

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Agricultural Sciences in China 2001年第1期 107-115页

作者： YANG Jian-chang WANG Wei WANG Zhi-qin LIU Li-jun ding Zhi-jia zhu Qing-sen Agricultural College Yangzhou University Yangzhou 225009 Agricultural College Yangzhou University Yangzhou 225009 Agricultural College Yangzhou University Yangzhou 225009 Agricultural College Yangzhou University Yangzhou 225009 Seed Station of Yiling Township Jiangdu County Agricultural College Yangzhou University Yangzhou 225009

The dry-raised seedlings (D-RS)of rice had obvious superiority in tillering and growth after transplanting. Especially under the condition of water-saving irrigation or low soil moisture, D-RS had more productive tillers, higher dry matter accumulation, larger grain-filling rate, slower senescence of leaves and stronger root activity during ripening, and higher grain yield, compared with the moist-raised seedlings (MRS). D-RS had smaller yield reduction than M-RS when subject to heavy water stress. The results suggested that D-RS had the ability to adapt to lower soil moisture in paddy field. Basedon the response of D-RS to soil moisture at each growth stage, the water-saving and high-yielding irrigation indices through controlling lowlimit soil water potential were proposed, i.e. soil water potential was - 15 - - 20 kPa from the recovery to the criticalleaf-age of productive tillering, - 20 - - 40 kPa from the critical leaf-age of productive tillering to secondary branch-differentiating stage, - 15 - - 25 kPa from secondary branch-differentiating stage to 20 days after heading and - 25 - - 35 kPa from 21 to 45 days after heading.

关键词： Rice Dry-raised seedlings Soil water potential Irrigation indices

Genetic Analysis and Gene Mapping of Short Root Mutant Rice ksr1

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Rice science 2011年第1期18卷 67-70页

作者： NING Yong-qiang ding Wo-na zhu Shi-hua Yu Hang-wei Yu Hang Lu Kai-xing Laboratory of Plant Molecular Biology Ningbo University Ningbo 315211 China

A short root mutant ksrl with the Kasalath background was isolated from an EMS-mutagenized population in rice. The root length of 6-day-old ksr1 seedlings was only about 20% of the wild type. Genetic analysis indicated that the short root phenotype of ksrl was controlled by a recessive mutation in a single nuclear-encoded gene. To map the ksrl mutation, an F2 population was generated by crossing the ksrl mutant with Nipponbare. The KSR1 locus was linked to the SSR marker RM1223 on rice chromosome 4. Eight new SSR markers and two InDel markers were developed around this marker. KSR1 gene was further mapped to a 155 kb region, flanked by the InDel marker 4-24725K and the SSR marker RM17182.

关键词： rice short root gene mapping molecular marker

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人工智能的文艺梦想和机器人的未来

华南师范大学学报（社会科学版） 2019年第5期 183-188,192页

作者：朱定局华南师范大学计算机学院

近年来,人工智能在多方面出现令人震惊的、接二连三的突破。机器人能诗会画甚至开始进行文学创作,让人们在惊喜之余又多了几分担忧。客观来讲,目前人工智能技术虽有很大突破,但在现有的理论和框架下,人工智能创作的文艺作品在内涵上仍... 详细信息

近年来,人工智能在多方面出现令人震惊的、接二连三的突破。机器人能诗会画甚至开始进行文学创作,让人们在惊喜之余又多了几分担忧。客观来讲,目前人工智能技术虽有很大突破,但在现有的理论和框架下,人工智能创作的文艺作品在内涵上仍然远远落后于人类。对未来而言,人工智能的发展是福是祸无法一概而论。在过去,人工智能主要用来提高生产效率进而促进人类物质文明的发展;而现在,人工智能能够创作文艺作品,必将对人类精神文明的建设产生深远影响。作为社会意识形态的一种,人工智能创作的文艺作品只有符合人类的道德伦理才能促进人类精神文明的发展;否则,反而会危害人类的精神文明建设。

关键词：人工智能文艺机器人伦理道德