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Flexible Reduced Loga.ithmic-Inverse Loma. Distribution with a.plica.ion for Bla.der Ca.cer

Open Journa. of Modelling a.d Simula.ion 2021年第4期9卷 351-369页

作者： Moha.ed M. Buza.ida. dina a. ramadan Beih S. El-Desouky Depa.tment of Ma.hema.ics Faculty of Science Mansoura University Mansoura Egypt

In this pa.er, a.new method for a.ding pa.a.eters to a.well-esta.lished distribution to obta.n more flexible new fa.ilies of distributions is a.plied to the inverse Loma. distribution (IFD). This method is known by th... 详细信息

In this paper, a new method for adding parameters to a well-established distribution to obtain more flexible new families of distributions is applied to the inverse Lomax distribution (IFD). This method is known by the flexible reduced logarithmic-X family of distribution (FRL-X). The proposed distribution can be called a flexible reduced logarithmic-inverse Lomax distribution (FRL-IL). The statistical and reliability properties of the proposed models are studied including moments, order statistics, moment generating function, and quantile function. The estimation of the model parameters by maximum likelihood and the observed information matrix are also discussed. In order to assess the potential of the newly created distribution. The extended model is applied to real data and the results are given and compared to other models.

关键词： Loma. Distribution Inverse Loma. Distribution Ha.a.d Ra.e Function Ma.imum Likelihood Estima.ors Skewness a.d Kurtosis Moment Genera.ing Function

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Sta.istica. Inference of Trunca.ed Weibull-Ra.leigh Distribution: Its Properties a.d a.plica.ions

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Open Journa. of Modelling a.d Simula.ion 2021年第3期9卷 281-298页

作者： Ema. H. Kha.ifa.dina a. ramadan B. S. El-Desouky Depa.tment of Ma.hema.ics Faculty of Science Mansoura University Mansoura Egypt

In this pa.er, we derived a.new distribution na.ed a. trunca.ed Weibull Ra.leigh (TW-R) distribution. Its cha.a.teriza.ion a.d sta.istica. properties a.e obta.ned, such a. relia.ility function, ha.a.d function, revers... 详细信息

In this paper, we derived a new distribution named as truncated Weibull Rayleigh (TW-R) distribution. Its characterization and statistical properties are obtained, such as reliability function, hazard function, reversed a.>a.>hazard rate function, cumulative hazard rate function, quantile function, rth moment, incomplete moments, Rényi and q entropies and order statistic. Parameter estimation is implemented using method of maximum-likelihood estimation and Fisher information matrix is derived. Finally, application of the presented new distribution to a real data representing the failure times of 63 airbcrafta.>a.> a.>a.>Windshield is given and its goodness-of-fit is demonstrated. In addition to, comparisons to other models are implemented to show the flexibility of the presenteda.>a.> a.>a.>model.a.>a.>

关键词： Ra.leigh Distribution Trunca.ed Weibull G-Fa.ily Moments Entropies Qua.tile Function Order Sta.istic Ma.imum Likelihood Estima.or

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a.sessing the lifetime performa.ce index of weighted Loma. distribution ba.ed on progressive type-Ⅱ censoring scheme for bla.der ca.cer

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Interna.iona. Journa. of Bioma.hema.ics 2021年第4期14卷 49-66页

作者： dina a.ramadan Depa.tment of Ma.hema.ics Faculty of Science Mansoura UniversityMansouraEgypt

In this pa.er,Hea.th-rela.ed qua.ity of life ha. not been a.equa.ely mea.ured in bla.der ca.cer.a.recently developed relia.le a.d disea.e-specific qua.ity of life instrument(Bla.der Ca.cer Index,RCI)wa. used to *** type Ⅱ censoring schemes ha.e potentia. usefulness in pra.tice where budget constra.nts in pla.e or there is a.necessity for the speedy *** test the process ca.a.ility,the lifetime performa.ce index Cl is widely recommended for eva.ua.ing the performa.ce of the producfs lifetime a.d eva.ua.ing the lifetime performa.ce index GL for the three-pa.a.eter Weighted-Loma. distribution(WLx)under progressive type-II censoring sa.ple for a.lower specifica.ion limit(L).The sta.istica. inference concerning CL is conducted via.obta.ning the ma.imum likelihood of Cl on the ba.e of progressive type-II *** a.ymptotic norma. distribution of the MLE of CL a.d the confidence interva. is ***,the hypothesis testing of CL for eva.ua.ing the lifetime performa.ce of WLx da.a.is ***,a.suming the conjuga.e prior distribution a.d squa.ed error loss function,this study constructs a.Ba.es estima.or of *** Ba.es estima.or of CL is then utilized to develop a.credible interva. in the condition of known ***,we propose a.Ba.esia. test to a.sess the lifetime performa.ce of *** a.so propose a.Ba.esia. test to a.sess the lifetime performa.ce of ***,two exa.ples a.e given,one of them is considering a.rea. life da.a.of the remission times of bla.der ca.cer pa.ients in endura.ce lifetime test a.d the other is a.simula.ed exa.ple to illustra.e the usa.e of the proposed procedure.

关键词： Lifetime performa.ce index Weighted-Loma. distribution progressively type-II right censoring

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Induction of sub-G0 a.rest a.d a.optosis by seed extra.t of Moringa.peregrina.Forssk.） Fiori in cervica. a.d prosta.e ca.cer cell lines

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Journa. of Integra.ive Medicine 2019年第6期17卷 410-422页

作者： Ma.ed Moha.ed Ma.er a.ou-Ha.hem dina Moha.ed a.o-elma.ty Noha.Mosta.a.Mesba. a.med Moha.ed a.d EL-Ma.goud Fa.ulty of Pha.ma.y Pharmacognosy DepartmentZagazig UniversityZagazig 44511Egypt Fa.ulty of Pha.ma.y Biochemistry DepartmentSuez Canal UniversityIsmailia 41522Egypt Egyptia. Interna.iona. Pha.ma.eutica.s Industries Compa.y Tenth of Ramadan City 44629Egypt

Objective: This study investiga.ed cytotoxicity a.d induction of a.optosis in huma. cervica. ca.cer cells(HELa. a.d prosta.e ca.cer cells(PC-3) using the most a.tive fra.tion of Moringa.peregrina.seed ***: Dried a.d powdered seeds were extra.ted using 95% etha.ol. The tota. etha.olic extra.t wa. further dissolved in distilled wa.er a.d sepa.a.ed into petroleum ether, chloroform, ethyl a.eta.e a.d a.ueous extra.ts. Ba.ed on the results of in vitro a.tica.cer studies of a.l extra.ts, the most highly a.tive extra.t wa. selected for eva.ua.ion of a.optosis induction a.d cell cycle a.a.ysis on HELa.a.d PC-3 cells a. its ha.f ma.ima. inhibitory concentra.ion using flow cytometry;DNa.fra.menta.ion by a.a.ose gel electrophoresis a.d the expression of protein were mea.ured by Western ***: The chloroform fra.tion from the etha.olic extra.t of M. peregrina.CFEE) wa. the most a.tive a.titumor fra.tion. The selectivity index, determined using the norma. Vero cell line, indica.ed tha. CFEE ha. a.high degree of selectivity a.a.nst HELa.a.d PC-3 cells. CFEE induced a.optosis, confirmed by cell cycle a.rest a. sub-G0 pha.e a.d DNa.fra.menta.ion. CFEE induced a. increa.e in mRNa.expression of ca.pa.e-3, a.decrea.e in Bcl-2 mRNa.expression, a.d decrea.ed a.P levels. CFEE increa.ed protein expression of ca.pa.e-3 a.d decrea.ed protein expression of poly-a.P-ribose polymera.e-1(Pa.P-1).Flow cytometric a.a.ysis showed a. a.precia.le increa.e in the number of cells in the ea.ly a.optotic sta.e in CFEE-trea.ed HELa.a.d PC-3 cells. CFEE trea.ment significa.tly increa.ed lipid peroxida.ion(ma.ondia.dehyde level) in HELa.a.d PC-3 ***: Seed extra.t of M. peregrina.displa.ed a.significa.t a.titumor effect through a.optosis induction in HELa.a.d PC-3 cells.

关键词： Moringa.peregrina Fra.tiona.ion a.tiprolifera.ion a.optosis

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