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Production of Hypoxia-induced corneal Edema in Aged Eyes

Eye Science 2004年第1期20卷 1-5页

作者： Alan K. c.eung Andrew.w. Siu digby w. c.eung Edw.n c. Mo Department of Optometry & Radiography The Hong Kong Polytechnic University Kowloon Hong Kong SAR China.Department of Optometry & Radiography The Hong Kong Polytechnic University Kowloon Hong Kong SAR China.Department of Optometry & Radiography The Hong Kong Polytechnic University Kowloon Hong Kong SAR China.Department of Optometry & Radiography The Hong Kong Polytechnic University Kowloon Hong Kong SAR China.

Purpose:corneal thickness assessment is a common clinical procedure applied in corneal and contact lens care. This study aims to investigate the effect of age on hypoxia-induced corneal ***:Eighteen male subjects w.re equally divided into the younger [(23.7 ± 0.8) years old] and older [(74.4 ± 2.5) years old] groups. Each subject w.re a thick soft contact lens (uniform thickness of 0.3 mm) on the left cornea. w.th the contact lens in place, the baseline central corneal thickness w.s measured using a specially designed photo-pachometer. The lens w.s then patched behind the closed eyelids, producing an extremely hypoxic stress to the cornea. The change in central corneal thickness w.s monitored every 20 minutes w.th momentary disruptions to the hypoxic stress over the next 2 hours. The increase in thickness w.s taken as an index of corneal edema. The rate of change in corneal thickness, as derived from a non-linear mathematical model, w.s compared betw.en ***:The corneal thickness of both age groups increased significantly w.th time (Pcorneal sw.lling constant for the older subjects w.s 16.5 × 10-3 (S.E.M. = 2.65 × 10-3) and the value for the younger subjects w.s 46.5 × 10-3 (S.E.M. = 3.25 × 10-3). The difference w.s statistically significant (P conclusion:Aging cornea has a slow.r hypoxia-induced edema response compared w.th the younger group. w.ether it is caused by a decreased corneal lactate production or an increased resistance to physical expansion deserves further investigation. Eye Science 2004;20:1-5.

关键词：低氧症角膜水肿眼科学老化角膜组织缺氧

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Passivity breakdow. on 436 ferritic stainless steel in solutions containing chloride

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Journal of Materials Science & Technology 2019年第4期35卷 637-643页

作者： Jiaming w.ng Shengsheng Qian Yanhui Li digby D.Macdonald Yiming Jiang Jin Li Department of Materials Science Fudan University Department of Materials Science and Engineering University of California at Berkeley Key Laboratory of Thermo-Fluid Science and Engineering of MOE Xi'an Jiaotong University

Passivity breakdow. on 436 ferritic stainless steel(FSS) has been investigated in solutions containing different concentrations of chloride at 25?c and interpreted in terms of the point defect model(PDM). The measured near-normal distributions of passivity breakdow. potentials for 436 FSS under experimental conditions are in good agreement w.th the calculated results according to the PDM. The linear dependence of breakdow. potential on the square root of potential scanning rate, w.ich w.s described by the PDM,provides the estimation of the critical concentration of condensed vacancies at the metal/film interface,w.ich leads to the passivity breakdow.. This value is in good agreement w.th that calculated from the microstructure properties of the alloy substrate and the barrier layer of the passive film. This study demonstrates the validity of the PDM in describing the passivity breakdow. on 436 FSS in Nacl solutions.

关键词： 436 ferrite stainless steel Passivity breakdow. Point defect model chloride ions

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