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Resolution enhancement with deblurring by pixel reassignment

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Advanced Photonics 2023年第6期5卷 59-71页

作者： Bingying Zhao Jerome mertz Boston University Department of Electrical and Computer EngineeringBostonMassachusettsUnited States Boston University Department of Biomedical EngineeringBostonMassachusettsUnited States

Improving the spatial resolution of a fluorescence microscope has been an ongoing challenge in the imaging *** address this challenge,a variety of approaches have been taken,ranging from instrumentation development to image *** example of the latter is deconvolution,where images are numerically deblurred based on a knowledge of the microscope point spread ***,deconvolution can easily lead to noise-amplification *** by postprocessing can also lead to negativities or fail to conserve local linearity between sample and *** describe here a simple image deblurring algorithm based on pixel reassignment that inherently avoids such artifacts and can be applied to general microscope modalities and fluorophore *** algorithm helps distinguish nearby fluorophores,even when these are separated by distances smaller than the conventional resolution limit,helping facilitate,for example,the application of single-molecule localization microscopy in dense *** demonstrate the versatility and performance of our algorithm under a variety of imaging conditions.

关键词： image deblurring microscopy bio-imaging image reconstruction optical resolution

Likelihood of hospitalization for a chronic respiratory condition following pediatric infection with enterovirus and rhinovirus strains

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Infectious Medicine 2022年第4期1卷 245-252页

作者： Charlotte Switzer Chris PVerschoor Kenneth Gavina Dominik mertz Kathy Luinstra Jeffrey MPernica Marek Smieja Dept.of Health Methods Evaluation and ImpactMcMaster UniversityHamiltonON CANADA Dept.of Medicine McMaster UniversityHamiltonON CANADA Dept.of Pediatrics McMaster UniversityHamiltonON CANADA Dept.of Pathology and Molecular Medicine McMaster UniversityHamiltonON CANADA Research Institute of St Joseph’s Healthcare Hamilton HamiltonON CANADA Health Sciences North Research Institute SudburyON CANADA

Background:Rhino-enteroviruses,particularly enterovirus strain D68(EV-D68),have been associated with severe respiratory distress in *** goal of this study was to compare the long-term outcomes of children with EV-D68 infection to that of children with other enterovirus/***:Nasopharyngeal swabs from 174 children presenting with respiratory distress were tested by PCR for respiratory *** primary outcome was diagnosis of a chronic respiratory condition within the followup *** to intensive care,and length of stay were *** ratios were determined using multinomial logistic ***:During 5 years of follow-up,the crude odds of diagnosis with a chronic respiratory condition were significantly more likely in EV-D68 cases(OR:1.95,95%CI:1.02,3.82),but failed to remain significant after adjusting for a past history of *** admission for a primary concern of asthma,length of stay both in hospital and intensive care were significantly longer in EV-D68 cases(OR:2.10[95%CI:1.56,2.82,p<0.001])and(OR:5.18[95%CI:1.90,6.28,p<0.001]),*** adjustment for a history of asthma,EV-D68 cases had significantly longer length of stay in hospital,admitted for 1.94 days for each day that controls were admitted(95%CI:1.40,2.68).In admissions to intensive care,EV-D68 cases spent 2.74 days for each day of admission in controls(95%CI:1.62,4.97,p<0.001).Conclusions:Ours is first study to assess prognostic respiratory outcomes of patients infected with EV-D68 in *** study finds that EV-D68 cases were significantly more likely be hospitalized for longer than other enterovirus/rhinovirus controls in subsequent admissions for respiratory *** for intensive care was significantly longer in EV-D68 *** next steps will be validation in a larger sample size.

关键词： Enterovirus-D68 Pediatric infectious disease Respiratory infection Asthma

Statistical learning of engineered topological phases in the kagome superlattice of AV_(3)Sb_(5)

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npj Computational Materials 2022年第1期8卷 624-629页

作者： Thomas mertz Paul Wunderlich Shinibali Bhattacharyya Francesco Ferrari Roser Valentí Institut für Theoretische Physik Goethe-UniversitätFrankfurt am MainGermany

Recent experimental findings have reported the presence of unconventional charge orders in the enlarged(2×2)unit-cell of kagome metals AV3Sb5(A=K,Rb,Cs)and hinted towards specific topological *** by these discoveries,we investigate the types of topological phases that can be realized in such kagome *** this context,we employ a recently introduced statistical method capable of constructing topological models for any generic *** analyzing large data sets generated from symmetry-guided distributions of randomized tight-binding parameters,and labeled with the corresponding topological index,we extract physically meaningful *** illustrate the possible real-space manifestations of charge and bond modulations and associated flux patterns for different topological classes,and discuss their relation to present theoretical predictions and experimental signatures for the AV_(3)Sb_(5)***,we predict higher-order topological phases that may be realized by appropriately manipulating the currently known systems.

关键词： topological signature meaningful

Eckfeld Maar:Window into an Eocene Terrestrial Habitat in Central Europe

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Acta Geologica Sinica(English Edition) 2010年第4期84卷 984-1009页

作者： Herbert LUTZ Uwe KAULFUSS Torsten WAPPLER Werner LHNERTZ Volker WILDE Dieter F.mertz Jens MINGRAM Jens L.FRANZEN Herbert FRANKENHUSER Martin KOZIOL Mainz Natural History Museum/State Collection for Natural History of Rhineland-Palatinate MainzGermany Department of Geology University of OtagoDunedinNew Zealand Section Palaeontology Steinmann InstituteUniversity of BonnBonnGermany Hermann-Josef-Kolleg Steinfeld Kall-SteinfeldGermany Section Palaeobotanik Senckenberg Research Institute and Natural History MuseumFrankfurt am MainGermany Institute for Geosciences Johannes Gutenberg University MainzMainzGermany Section Climate Dynamics and Landscape Evolution Helmholtz Centre Potsdam GFZ German Research Centre for GeosciencesPotsdamGermany Jakobistr. Titisee-NeustadtGermany Maarmuseum Manderscheid/State Collection for Natural History of Rhineland-Palatinate ManderscheidGermany

To mark the occasion of the 175th anniversary of the Rheinische Naturforschende Gesellschaft in 2009 and of the centennial of the Mainz Natural History Museum in 2010, we present a short account of our present knowledge of the Eckfeld Maar after 20 years of continuous research. This paper does not attempt to include all of the detailed results on the geology of the Eckfeld site or its biota. To date, nearly 250 papers and books have been published since the start of our project. An up-to-date list of these publications can be found at ***.

关键词： maar lake Eocene central Europe fossil Rhenish shield

Introducing the Principles of Tendon Transfer for Surgical Trainees to Improve Anatomical Knowledge

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Open Journal of Orthopedics 2023年第7期13卷 306-319页

作者： Neil Ashwood Jamie Hind Andrew Dekker Mosab Elgalli Temitayo Alawoya Tamara mertz Research Institute University of Wolverhampton Wolverhampton UK Department of Trauma & Orthopaedics University Hospitals Derby and Burton Burton on Trent UK Department of Trauma & Orthopaedics Oxford University Oxford UK Stoke Mandeville Hospital Buckinghamshire Healthcare NHS Trust Aylesbury UK Newham University Hospital London UK Department of Burns and Plastic surgery North Bristol NHS Trust Bristol UK

This article reviewed the principles and outcomes of tendon transfer procedures described in the literature to restore function following injuries delivered in a workshop as a way of improving basic science and anatomical knowledge in surgical trainees preparing for surgical examinations. Post intervention surveys showed an improvement in trainees’ familiarity with musculoskeletal anatomy and engagement in learning with improved readiness for surgical examinations.

关键词： Professionalism Tendon Transfer Surgical Training Surgical Trainees: Anatomical Knowledge

实现安全系统内编程功能 Flash FPGA出任“防盗门”

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电子测试（新电子） 2006年第2期 26-29页

作者： Michael mertz Actel公司

近年来,FPGA 的应用领域逐渐扩大,其独特的灵活性使设计者可以在设计中甚至是设计后对器件重复编程,更改系统的功能,缩短产品上市时间。然而,在各厂商以独有的功能吸引消费者眼球的同时也招致对手的觊觎,这就对 FPGA 的安全性提出更高... 详细信息

近年来,FPGA 的应用领域逐渐扩大,其独特的灵活性使设计者可以在设计中甚至是设计后对器件重复编程,更改系统的功能,缩短产品上市时间。然而,在各厂商以独有的功能吸引消费者眼球的同时也招致对手的觊觎,这就对 FPGA 的安全性提出更高要求。基于 Flash 的 FPGA 能满足 ISP 的安全要求,防止盗版、盗取数据、篡改产品及黑客攻击等问题,提供安全的使用环境。

关键词： Flash FPGA 安全系统编程功能防盗门设计者上市时间安全要求黑客攻击使用环境

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必需微量元素

环境卫生学杂志 1984年第1期 23-26+19页

作者： mertz W 秦振声

人体每天所需要的微量元素为50μg～18mg。它们具有特殊的功能,且是生命不可缺少的元素。临界的或严重的微量元素不平衡,可以认为是具有卫生学意义的几种疾病的危险因素,但要证实其因果关系尚有待于更全面地了解其作用机制,具备更完善... 详细信息

人体每天所需要的微量元素为50μg～18mg。它们具有特殊的功能,且是生命不可缺少的元素。临界的或严重的微量元素不平衡,可以认为是具有卫生学意义的几种疾病的危险因素,但要证实其因果关系尚有待于更全面地了解其作用机制,具备更完善的分析方法及功能性试验,来测定人体内临界微量元素的情况。

关键词：微量元素功能卫生学痕量元素动物

Osteogenesis imperfecta and complications due to pelvic narrowing: case and review

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Open Journal of Pediatrics 2011年第4期1卷 64-66页

作者： Jakob Bie Granild-Jensen Line Granild Bie mertz Soren Rittig Gratien Andersen John Rosendahl Oestergaard 不详

We describe a case of pelvic narrowing in a patient with osteogenesis imperfecta (OI) type III and complications consisting of deep venous thrombosis, hydronephrosis and faeculomas. The literature is reviewed and the management is discussed. Conclusion: Monitoring of OI type III patients for pelvic narrowing and complications is recommended.

关键词： Acetabular Protrusion Bisphosphonate Constipation Deep Venous Thrombosis Hydronephrosis Pelvis

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混合信号FPGA的“智能”系统验证流程

电子与电脑 2006年第11期6卷 108-110页

作者： Michael mertz Venkatesh Narayanan Actel公司

为了满足市场对更高性能、更小体积及更低成本和功耗不断增长的需求，系统设计人员需要将更高级别的混合信号功能集成到系统级芯片（SoC）中。随着这些SoC设计中混合信号器件的增加，基本的功能验证在半导体的早期制备中变得十分重要。... 详细信息

为了满足市场对更高性能、更小体积及更低成本和功耗不断增长的需求，系统设计人员需要将更高级别的混合信号功能集成到系统级芯片（SoC）中。随着这些SoC设计中混合信号器件的增加，基本的功能验证在半导体的早期制备中变得十分重要。没有这种验证，系统设计人员将需要为半导体制备的返工耗费数以百万计美元，并且浪费宝贵的设计和验证资源，而且还可能错过产品上市的良机。幸运的是，现在的设计人员比过去有更多的选择设计混合信号系统不再局限于混合信号ASIC、模拟MCU或分立组件。FPGA为系统集成开辟了新的方向，能够改善系统集成的各个方面，如降低总体系统成本、提高可靠性、实现可重配置性、缩短开发时间等。这种以可编程系统芯片（PSC）为核心的崭新解决方案将FPGA门、嵌入式Flash和模拟功能集成在单一可编程器件中，提供理想的低成本方案，具备真正的可编程性，而且可让系统设计人员快速地设计和开发复杂的混合信号系统。

关键词：混合信号系统系统验证 FPGA 嵌入式Flash 设计人员可编程系统芯片可编程器件智能