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A novel and stretchable carbon-nanotube/Ni@TiO_(2):W photocatalytic composite for the complete removal of diclofenac drug from the drinking water

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Journal of Environmental Sciences 2023年第4期126卷 575-589页

作者： Ernesto Valadez-Renteria Rafael perez-Gonzalez Christian Gomez-Solis Luis Armando Diaz-Torres Armando Encinas Jorge Oliva Vicente rodriguez-Gonzalez Consejo Nacional de Ciencia y Tecnología-División de Materiales Avanzados Instituto Potosino de Investigación Científica y TecnológicaSan Luis Potosí78216México División de Ciencias e Ingenierías Universidad de GuanajuatoLeón 37150México Grupo de Espectroscopia de Materiales Avanzados y Nanoestructurados(GEMANA) Centro de Investigaciones enópticaA.C.Lomas Del CampestreLeón 37150México

We present the structural,morphological and photocatalytic properties of stretchable composites made with carbon nanotubes (CNTs),silicon rubber and Ni@TiO_(2):W nanoparticles(TiWNi NPs) with average size of 37±2 *** images showed that the TiWNi NPs decorated the surface of the CNT fibers,which are oriented in a preferential *** NPs presented a mixture of anatase/rutile phases with cubic *** performance of the TiWNi powders and stretchable composites was evaluated for the photocatalytic degradation of diclofenac (DCF) anti-inflammatory drug under ultraviolet-visible *** results revealed that the maximum DCF degradation percentages were 34.6%,91.9%,97.1%,98.5%and 100%for the CNT composite (stretched at 0%),TiWNi powders,CNT+TiWNi(stretched at 0%),CNT+TiWNi (stretched at 50%) and CNT+TiWNi (stretched at 100%),***,stretching the CNT+TiWNi composites was a good strategy to enhance the DCF degradation percentage from 97.1%to 100%,since stretching created additional defects (oxygen vacancies) that acted as electron sink,delaying the electron-hole recombination,and favors the DCF ***/absorbance measurements confirmed the presence of such ***,the reactive oxygen species (ROS) were determined by the scavenger’s experiments and found that the main ROS were the·OH and O_(2)-radicals,which attacked the DCF molecules,causing their *** results of this investigation confirmed that the stretchable CNT/TiWNi-based composites are a viable alternative to remove pharmaceutical contaminants from water and can be manually separated from the decontaminated water,which is unviable using photocatalytic powders.

关键词： Diclofenac Pharmaceutical contaminant TiO_(2) Carbon nanotubes Stretchable composite Photocatalysis

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A new oxidative pathway of nitric oxide production from oximes in plants

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Molecular Plant 2024年第1期17卷 178-198页

作者： Pedro Lopez-Gomez Javier Buezo Marina Urra Alfonso Cornejo Raquel Esteban Jorge Fernandez de los Reyes Estibaliz Urarte Estefania rodriguez-Dobreva Alejandro Chamizo-Ampudia Alejandro Eguaras Sebastian Wolf Daniel Marino Victor Martinez-Merino Jose F.Moran Institute for Multidisciplinary Research in Applied Biology(IMAB) Department of SciencesPublic University of Navarre(UPNA)Avda.de Pamplona 12331192 MutilvaSpain Institute for Advanced Materials and Mathematics(INAMAT2) Department of SciencesPublic University of Navarre(UPNA)Campus de Arosadia31006 PamplonaSpain Department of Plant Biology and Ecology University of the Basque Country(UPV/EHU)Sarriena s/nApdo.64448080 BilbaoSpain Center for Plant Molecular Biology(ZMBP) University of TubingenGeschwister-Scholl-Platz72074 TubingenGermany Institute of Natural Resources and Agrobiology of Salamanca(IRNASA) Department of Plant-Microorganism InteractionsSpanish National Research Council(CSIC)Cordel de Merinas40-5237008SalamancaSpain Department of Biochemistry Area of Molecular BiologyVeterinary FacultyUniversity of LeonCampus de Vegazanas/n.24071 LeonSpain

Nitric oxide(NO)is an essential reactive oxygen species and a signal molecule in *** several studies have proposed the occurrence of oxidative NO production,only reductive routes for NO production,such as the nitrate(NO_(3)^(-))-upper-reductase pathway,have been evidenced to date in land ***,plants grown axenically with ammonium as the sole source of nitrogen exhibit contents of nitrite and NO3−,evidencing the existence of a metabolic pathway for oxidative production of *** hypothesized that oximes,such as indole-3-acetaldoxime(IAOx),a precursor to indole-3-acetic acid,are intermediate oxidation products in NO *** detected the production of NO from IAOx and other oximes catalyzed by peroxidase(POD)enzyme using both 4-amino-5-methylamino-2′,7′-difluorescein fluorescence and *** stimulated the reaction,while superoxide dismutase inhibited ***,mouse NO synthase can also use IAOx to produce NO at a lower rate than *** provided a full mechanism for POD-dependent NO production from IAOx consistent with the experimental data and supported by density functional theory *** showed that the addition of IAOx to extracts from Medicago truncatula increased the in vitro production of NO,while in vivo supplementation of IAOx and other oximes increased the number of lateral roots,as shown for NO donors,and a more than 10-fold increase in IAOx dehydratase ***,we found that in vivo supplementation of IAOx increased NO production in Arabidopsis thaliana wild-type plants,while prx33-34 mutant plants,defective in POD33-34,had reduced *** data show that the release of NO by IAOx,as well as its auxinic effect,explain the superroot ***,our study reveals that plants produce NO utilizing diverse molecules such as oximes,POD,and flavins,which are widely distributed in the plant kingdom,thus introducing a long-awaited oxidative pathway to NO production in plants.T

关键词： ammonium oxidation auxin nitric oxide oxime peroxidase root phenotype

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Epidemiology, Clinical Features and Antifungal Resistance Profile of Candida auris in Africa: Systematic Review

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Journal of Biosciences and Medicines 2024年第1期12卷 126-149页

作者： Isidore Wendkièta Yerbanga Seydou Nakanabo Diallo Toussaint Rouamba Delwendé Florence Ouedraogo Katrien Lagrou Rita Oladele Jean-Pierre Gangneux Olivier Denis Hector rodriguez-Villalobos Isabel Montesinos Sanata Bamba Centre Hospitalier Universitaire Régional de Ouahigouya Ouahigouya Burkina Faso Ecole Doctorale des Sciences De la Santé Université Nazi Boni Bobo-Dioulasso Burkina Faso Centre Muraz/Institut National de Santé Publique Bobo-Dioulasso Burkina Faso Clinical Research Unit of Nanoro Institute for Research in Health Sciences National Center for Scientific and Technological Research Ouagadougou Burkina Faso Department of Microbiology Immunology and Transplantation KU Leuven Leuven Belgium and Department of Laboratory Medicine and National Reference Center for Mycosis Excellence Center for Medical Mycology (ECMM) University Hospitals Leuven Leuven Belgium College of Medicine University of Lagos Lagos Nigeria Univ Rennes CHU Rennes Inserm Irset (Institut de recherche en santé environnement et travail) European ECMM Excellence Center in Medical Mycology Université de Rennes Rennes France Department of Microbiology CHU Namur site-Godinne Université Catholique de Louvain Yvoir Belgium Ecole de Santé Publique Université Libre de Bruxelles Brussels Belgium Department of Microbiology Cliniques Universitaires Saint-Luc—Université Catholique de Louvain Bruxelles Belgium Centre Hospitalier Universitaire Sour? Sanou Bobo-Dioulasso Burkina Faso

Candida auris since it discovery in 2009 is becoming a severe threat to human health due to its very quickly spread, its worldwide high resistance to systemic antifungal drugs. In resource-constrained settings where several conditions are met for its emergence and spread, this worrisome fungus could cause large hospital and/or community-based outbreaks. This review aimed to summarize the available data on C. auris in Africa focusing on its epidemiology and antifungal resistance profile. Major databases were searched for articles on the epidemiology and antifungal resistance profile of C. auris in Africa. Out of 2,521 articles identified 22 met the inclusion criteria. In Africa, nearly 89% of African countries have no published data on C. auris. The prevalence of C. auris in Africa was 8.74%. The case fatality rate of C. auris infection in Africa was 39.46%. The main C. auris risk factors reported in Africa were cardiovascular disease, renal failure, diabetes, HIV, recent intake of antimicrobial drugs, ICU admissions, surgery, hemodialysis, parenteral nutrition and indwelling devices. Four phylogenetic clades were reported in Africa, namely clades I, II, III and IV. Candida auris showed a pan-African very high resistance rate to fluconazole, moderate resistance to amphotericin B, and high susceptibility to echinocandins. Finally, C. auris clade-specific mutations were observed within the ERG2, ERG3, ERG9, ERG11, FKS1, TAC1b and MRR1 genes in Africa. This systematic review showed the presence of C. auris in the African continent and a worrying unavailability of data on this resilient fungus in most African countries.

关键词： Africa Antifungal Resistance Candida auris Clinical Features Phylogenetic Clades

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Current role and future perspectives of artificial intelligence in echocardiography

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World Journal of Cardiology 2023年第6期15卷 284-292页

作者： Rafael Vidal-perez Julia Grapsa Alberto Bouzas-Mosquera Ricardo Fontes-Carvalho Jose Manuel Vazquez-rodriguez Servicio de Cardiología Unidad de Imagen y Función CardíacaComplexo Hospitalario Universitario A Coruña Centro de Investigación Biomédica en Red-Instituto de Salud Carlos ⅢA Coruña 15006Spain Department of Cardiology Guys and St Thomas NHS TrustLondon SE17EHUnited Kingdom Cardiology Department Centro Hospitalar de Vila Nova de Gaia/EspinhoVilanova de Gaia 4434-502Portugal Cardiovascular R&D Centre-UnIC@RISE Department of Surgery and PhysiologyFaculty of Medicine of the University of PortoPorto 4200-319Portugal Servicio de Cardiología Complexo Hospitalario Universitario A CoruñaA Coruña 15006Spain

Echocardiography is an essential tool in diagnostic cardiology and is fundamental to clinical *** intelligence(AI)can help health care providers serving as a valuable diagnostic tool for physicians in the field of echocardiography specially on the automation of measurements and interpretation of *** addition,it can help expand the capabilities of research and discover alternative pathways in medical management specially on *** this review article,we describe the current role and future perspectives of AI in echocardiography.

关键词： Echocardiography Artificial intelligence Machine learning Deep learning Prognosis

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Effect of Mushroom Extract Hericium erinaceus on Spatial Memory and Morphology of Neurons in the CA1 and CA3 Regions of the Hippocampus in Ovariectomized Rats

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Open Journal of Veterinary Medicine 2024年第7期14卷 163-179页

作者： Lucia Garcia-Delgado Mariana Monserrath Verdía-Venegas Jacinto Bañuelos-Pineda Esther Albarrán-Rodríguez Guillermo Nolasco-rodriguez José Ricardo Cuellar-Pérez Sergio Fausto-Guerra Manuel Rosales-Cortés Master in Behavioral Sciences Institute of Neurosciences University of Guadalajara Zapopan Mexico Department of Veterinary Medicine Division of Veterinary Sciences CUCBA University of Guadalajara Zapopan Mexico Botany and Zoology Laboratory CUCBA University of Guadalajara Zapopan Mexico

Various studies indicate that low levels of estradiol negatively impact cognitive abilities. Extracts from the fungus Hericium erinaceus (HE) contain bioactive components that promote the proper functioning of the nervous system and potential effects on protection against neurodegenerative diseases, including dementia and motor dysfunctions. The objective was to evaluate the effects of the administration of the HE mushroom extract on visuospatial memory and morphology of neurons in the CA1 and CA3 regions of the hippocampus in ovariectomized rats. 40 young Wistar rats weighing 90 ± 10 g BW were used, which were distributed into four groups of 10 animals;Control Group, non-ovariectomized and untreated rats;Group E2, ovariectomized rats treated with estradiol (2 μg/kg/body weight);Group HE, ovariectomized rats treated with the extract of the fungus Hericium erinaceus (0.5 mg/kg body weight) and Group Ovx/ST, ovariectomized rats, without treatment. The animals were tested in the Barnes and Open Field maze, then they were sacrificed, and their brains were obtained to perform a histological analysis of neuronal morphology in the CA1 and CA3 areas of the hippocampus. The most outstanding results showed that the Ovx/ST group recorded the longest time to arrive at the escape box and stay in the Barnes maze. A correlation was observed between neuronal damage and function;in the groups that did not present satisfactory performance in the maze tests, morphological alterations were identified such as the presence of some neuronal somata with degeneration characteristics such as pyknosis, nuclear basophilia and shrinkage of the cells. Its soma, as well as a decrease in the nuclear area of CA1 and CA3 neurons. It is concluded that the fungus Hericium erinaceus exerted a neuroprotective effect on the neuronal bodies of the hippocampus, associated with better performance in the visuospatial recognition memory test.

关键词： Ovariectomized Rats Ovarian Hypofunction Estradiol Hericium erinaceus Barnes Circular Labyrinth Open Field Labyrinth

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Deep convolutional neural network for damaged vegetation segmentation from RGB images based on virtual NIR-channel estimation

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Artificial Intelligence in Agriculture 2022年第1期6卷 199-210页

作者： Artzai Picon Arantza Bereciartua-perez Itziar Eguskiza Javier Romero-rodriguez Carlos Javier Jimenez-Ruiz Till Eggers Christian Klukas Ramon Navarra-Mestre TECNALIA Basque Research and Technology Alliance(BRTA)Parque Tecnológico de BizkaiaC/Geldo.Edificio 700E-48160 Derio-BizkaiaSpain University of the Basque Country Plaza Torres Quevedo48013 BilbaoSpain BASF Espanola S.L.Carretera A376 41710 Utrera SevillaSpain BASF SE Speyererstrasse 267117 LimburgerhofGermany

Performing accurate and automated semantic segmentation of vegetation is a first algorithmic step towards more complex models that can extract accurate biological information on crop health,weed presence and phenological state,among ***,models based on normalized difference vegetation index(NDVI),near infrared channel(NIR)or RGB have been a good indicator of vegetation ***,these methods are not suitable for accurately segmenting vegetation showing damage,which precludes their use for downstream phenotyping *** this paper,we propose a comprehensive method for robust vegetation segmentation in RGB images that can cope with damaged *** method consists of a first regression convolutional neural network to estimate a virtual NIR channel from an RGB ***,we compute two newly proposed vegetation indices from this estimated virtual NIR:the infrared-dark channel subtraction(IDCS)and infrared-dark channel ratio(IDCR)***,both the RGB image and the estimated indices are fed into a semantic segmentation deep convolutional neural network to train a model to segment vegetation regardless of damage or *** model was tested on 84 plots containing thirteen vegetation species showing different degrees of damage and acquired over 28 *** results show that the best segmentation is obtained when the input image is augmented with the proposed virtual NIR channel(F1=0:94)and with the proposed IDCR and IDCS vegetation indices(F1=0:95)derived from the estimated NIR channel,while the use of only the image or RGB indices lead to inferior performance(RGB(F1=0:90)NIR(F1=0:82)or NDVI(F1=0:89)channel).The proposed method provides an end-to-end land cover map segmentation method directly from simple RGB images and has been successfully validated in real field conditions.

关键词： Vegetation indices estimation Vegetation coverage map Near infrared estimation Convolutional neural network Deep learning

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Automatic Bone Surface Restoration for Markerless Computer-Assisted Orthopaedic Surgery

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Chinese Journal of Mechanical Engineering 2022年第1期35卷 85-90页

作者： Xue Hu Ferdinando rodriguez y Baena Mechatronics in Medicine Laboratory Imperial College LondonLondonUK

An automatic markerless knee tracking and registration algorithm has been proposed in the literature to avoid the marker insertion required by conventional computer-assisted knee surgery,resulting in a shorter and less invasive surgical ***,such an algorithm considers intact femur geometry *** bone surface modification is inevitable due to intra-operative *** mismatched correspondences will degrade the reliability of registered target *** solve this problem,this work proposed a supervised deep neural network to automatically restore the surface of processed *** network was trained on a synthetic dataset that consists of real depth captures of a model leg and simulated realistic femur *** to the evaluation on both synthetic data and real-time captures,the registration quality can be effectively improved by surface *** improvement in tracking accuracy is only evident over test data,indicating the need for future enhancement of the dataset and network.

关键词： Bone surface reconstruction Computer assisted orthopedic surgery Markerless femur tracking

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Effective Interaction Force between an Electric Charge and a Magnetic Dipole and Locality (or Nonlocality) in Quantum Effects of the Aharonov–Bohm Type

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Chinese Physics Letters 2021年第3期38卷 39-43页

作者： Gianfranco Spavieri George T.Gillies Miguel rodriguez Maribel perez Centro de Física Fundamental Facultad de CienciasUniversidad de Los AndesMérida 5101Venezuela Department of Mechanical and Aerospace Engineering University of VirginiaCharlottesvilleVA 22904USA Departamento de Física Facultad de Ciencia y TecnologíaUniversidad de CaraboboNaguanagua 2001Venezuela Carrera de Ingeniería Ambiental Facultad de IngenieríaUniversidad Nacional de ChimborazoRiobamba 100150Ecuador

Classical electrodynamics foresees that the effective interaction force between a moving charge and a magnetic dipole is modified by the time-varying total momentum of the interaction fields. We derive the equations of motion of the particles from the total stress-energy tensor, assuming the validity of Maxwell’s equations and the total momentum conservation law. Applications to the effects of Aharonov–Bohm type show that the observed phase shift may be due to the relative lag between interfering particles caused by the effective local force.

关键词： force. momentum interaction

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Value of cardiac magnetic resonance on the risk stratification of cardiomyopathies

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World Journal of Cardiology 2023年第10期15卷 487-499页

作者： Rafael Vidal-perez Mariana Brandao Wael Zaher Ruben Casado-Arroyo Alberto Bouzas-Mosquera Ricardo Fontes-Carvalho Jose Manuel Vazquez-rodriguez Servicio de Cardiologia Unidad de Imagen y Funcion CardiacaComplexo Hospitalario Universitario A Coruña Centro de Investigacion Biomedica en Red de Enfermedades Cardiovasculares(CIBERCV)A Coruna 15006GaliciaSpain Department of Cardiology Centro Hospitalar de Vila Nova de Gaia/EspinhoVila Nova de Gaia 4434-502Portugal Department of Cardiology Hôpital ErasmeUniversite Libre de BruxellesBrussels 1070BrusselsBelgium Cardiovascular R&D Centre-UnIC@RISE Department of Surgery and PhysiologyFaculty of Medicine of the University of PortoPorto 4200-319Portugal Servicio de Cardiología Complexo Hospitalario Universitario A CoruñaA Coruña 15006A CoruñaSpain

Cardiomyopathies represent a diverse group of heart muscle diseases with varying etiologies,presenting a diagnostic challenge due to their heterogeneous *** evaluation using cardiac imaging techniques is impera-tive as symptoms can evolve over *** imaging approaches are pivotal for accurate diagnosis,treatment planning,and optimizing prognostic *** these,cardiovascular magnetic resonance(CMR)stands out for its ability to provide precise anatomical and functional *** manuscript ex-plores the significant contributions of CMR in the diagnosis and management of patients with cardiomyopathies,with special attention to risk ***’s high spatial resolution and tissue characterization capabilities enable early detec-tion and differentiation of various cardiomyopathy ***,it offers valuable insights into myocardial fibrosis,tissue viability,and left ven-tricular function,crucial parameters for risk stratification and predicting adverse cardiac *** integrating CMR into clinical practice,clinicians can tailor patient-specific treatment plans,implement timely interventions,and optimize long-term *** non-invasive nature of CMR reduces the need for invasive procedures,minimizing patient *** review highlights the vital role of CMR in monitoring disease progression,guiding treatment decisions,and identifying potential complications in patients with *** utilization of CMR has significantly advanced our understanding and management of these complex cardiac conditions,leading to improved patient outcomes and a more personalized approach to care.

关键词： Cardiac magnetic resonance Cardiomyopathies Prognosis Dilated cardiomyopathy Hypertrophic cardiomyopathy Restrictive cardiomyopathy

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Plant Proteins Are Smaller Because They Are Encoded by Fewer Exons than Animal Proteins

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Genomics, Proteomics & Bioinformatics 2016年第6期14卷 357-370页

作者： Obed Ramirez-Sachez Paulino perez-rodriguez Luis Delaye Axel Tiessen Genetic Engineering Department CINVESTAV Unidad IrapuatoIrapuatoCP 36821Mexico Colegio de Postgraduados Campus MontecilloTexcocoCP 56230Mexico

Protein size is an important biochemical feature since longer proteins can harbor more domains and therefore can display more biological functionalities than shorter proteins. We found remarkable differences in protein length, exon structure, and domain count among different phylo- genetic lineages. While eukaryotic proteins have an average size of 472 amino acid residues （aa）, average protein sizes in plant genomes are smaller than those of animals and fungi. Proteins unique to plants are -81 aa shorter than plant proteins conserved among other eukaryotic lineages. The smaller average size of plant proteins could neither be explained by endosymbiosis nor subcellular compartmentation nor exon size, but rather due to exon number. Metazoan proteins are encoded on average by -10 exons of small size [-176 nucleotides （nt）]. Streptophyta have on average only -5.7 exons of medium size （-230 nt）. Multicellular species code for large proteins by increasing the exon number, while most unicellular organisms employ rather larger exons （〉 400 nt）. Among subcellular compartments, membrane proteins are the largest （-520 aa）, whereas the smallest proteins correspond to the gene ontology group of ribosome （-240 aa）. Plant genes are encoded by half the number of exons and also contain fewer domains than animal proteins on average. Interestingly, endosymbiotic proteins that migrated to the plant nucleus became larger than their cyanobacterial orthologs. We thus conclude that plants have proteins larger than bacteria but smaller than animals or fungi. Compared to the average of eukaryotic species, plants have -34% more but -20% smaller proteins. This suggests that photosynthetic organisms are unique and deserve therefore special attention with regard to the evolutionary forces acting on their genomes and proteomes.

关键词： Digital proteome Eukarya Evolution Viridiplantae Polypeptide length

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