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Surgical Treatment of Craniopharyngiomas in Adults:Comparison between Primary Surgery and Surgery for Recurrence

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Current Medical Science 2022年第6期42卷 1119-1130页

作者： Rocío Evangelista zamora Florian Grimm Sasan Darius Adib Antje Bornemann Jürgen Honegger Department of Neurosurgery University of TübingenTübingen72076Germany Department of Neurosurgery Hospital Universitario Marqués de ValdecillaSantander39008Spain Institute of Neuropathology University of TübingenTübingen72076Germany

Objective Few studies have investigated the differences in outcomes between primary and repeat surgery for a craniopharyngioma in *** a result,a treatment concept for adult patients with a craniopharyngioma has not yet been *** present study aimed to retrospectively analyze adult patients with craniopharyngioma to compare surgical outcomes between primary surgery and surgery for *** The demographic and clinical data of 68 adult patients with craniopharyngioma who had primary surgery(n=50)or surgery for recurrence(n=18)were retrospectively *** addition,the patients were followed up for an average of 38.6 months(range:1–133 months).Results The cohorts of patients undergoing primary surgery or repeat surgery did not differ preoperatively in terms of demographic data,or radiological tumor ***,patients with recurrent craniopharyngioma had significantly more pituitary hormone deficits and hypothalamo-pituitary disorders before surgery compared with patients with newly diagnosed *** success rate of complete resection in primary surgery was 53.2%.Even after repeat surgery,a satisfactory rate of complete resection of 35.7%was *** morbidity was increased neither in patients with repeat surgery compared with those with primary surgery(postoperative bleeding P=0.560;meningitis P=1.000;CSF leak P=0.666;visual disturbance P=0.717)nor in patients with complete resection compared with those with partial *** found no difference in recurrence-free survival between initial surgery and repeat surgery(P=0.733).The recurrence rate was significantly lower after complete resection(6.9%)than after partial resection(47.8%;P<0.001).Conclusion Attempting complete resection is justified for not only those with newly diagnosed craniopharyngioma but also for those with recurrent ***,the surgeon must settle for less than total resection if postoperative morbidity is anticipated.

关键词： craniopharyngioma adulthood transcranial transsphenoidal primary surgery recurrence recurrence-free survival

Association of electrocardiographic markers with myocardial fibrosis as assessed by cardiac magnetic resonance in different clinical settings

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World Journal of Cardiology 2022年第9期14卷 483-495页

作者： George Bazoukis Sebastian garc.a-zamora GökselÇinier Sharen Lee Enes Elvin Gul JesúsÁlvarez-garc.a Gabi Miana Mertİlker Hayıroğlu Gary Tse Tong Liu Adrian Baranchuk Department of Cardiology Larnaca General HospitalLarnaca 6036Cyprus Department of Basic and Clinical Sciences University of Nicosia Medical SchoolNicosia 2414Cyprus Department of Cardiology Delta ClinicSanta Fe 341Argentina Department of Cardiology Dr.Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research CenterIstanbul 34668Turkey Cardiovascular Analytics Group Laboratory of Cardiovascular PhysiologyHong Kong 999077China Division of Cardiac Electrophysiology Madinah Cardiac CentreMadinah 42351Saudi Arabia Department of Cardiology Ramon y Cajal University HospitalMadrid 28034Spain Telehealth Center of Hospital das Clínicas Hong Kong 999077China Kent and Medway Medical School CanterburyCanterbury CT27FSUnited Kingdom Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease Department of CardiologyTianjin Institute of CardiologySecond Hospital of TianjinTianjin Medical UniversityTianjin 300211China Department of Cardiology The Second Hospital of Tianjin Medical UniversityTianjin 300211China Department of Cardiology Queen's UniversityOntario K7L 3N6Canada

BACKGROUND Cardiac magnetic resonance(CMR)is a unique tool for non-invasive tissue characterization,especially for identifying *** To present the existing data regarding the association of electrocardiographic(ECG)markers with myocardial fibrosis identified by CMR-late gadolinium enhancement(LGE).METHODS A systematic search was performed for identifying the relevant studies in Medline and Cochrane databases through February *** addition,we conducted a relevant search by Reference Citation Analysis(RCA)(https://***).RESULTS A total of 32 studies were *** hypertrophic cardiomyopathy(HCM),fragmented QRS(fQRS)is related to the presence and extent of myocardial *** and abnormal Q waves are associated with LGE in ischemic cardiomyopathy patients,while fQRS has also been related to fibrosis in *** score,abnormal Q waves,and notched QRS have also been associated with *** abnormalities as reflected by increased Tp-Te,negative Twaves,and higher QT dispersion are related to myocardial fibrosis in HCM *** patients with Duchenne muscular dystrophy,a significant correlation between fQRS and the amount of myocardial fibrosis as assessed by LGE-CMR was *** atrial fibrillation patients,advanced inter-atrial block is defined as P-wave duration≥120 ms,and biphasic morphology in inferior leads is related to left atrial *** Myocardial fibrosis,a reliable marker of prognosis in a broad spectrum of cardiovascular diseases,can be easily understood with an easily applicable ***,more data is needed on a specific disease basis to study the association of ECG markers and myocardial fibrosis as depicted by CMR.

关键词： Myocardial fibrosis Late gadolinium enhancement Electrocardiogram Cardiac magnetic resonance

Effects of Hedera helix L. removal on the understory early regeneration in an oak temperate forest in Mexico City

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Ecological Processes 2023年 438-449页

作者： Héctor Adrián Jiménez-Hernández Leticia Bonilla-Valencia Yuriana Martínez-Orea Mara Jessica zamora-Almazan Francisco Javier Espinosa-garc.a Silvia Castillo-Argüero Facultad de Ciencias Universidad Nacional Autónoma de México Instituto de Investigaciones en Ecosistemas y Sustentabilidad Universidad Nacional Autónoma de México

Background Hedera helix L. is an invasive weed species introduced in several regions of the world, so it is relevant to study its effects on the plant community and the changes occurring after its eradication. We established invaded(with/without removal of H. helix) and non-invaded(with/without removal of the understory) plots to compare some community attributes in an oak forest in Mexico City and monitored them every 2 months for 1 year, taking soil samples to compare some edaphic variables between the plots. If invasive species negatively affect natural regeneration, seedlings of native species would be less abundant in plots invaded by H. helix than in the non-invaded ones. As invasive species modify the soil microbiota through exudates and often allelochemicals, soil chemical variables would differ between invaded and non-invaded *** The abundance of native species was lower in the invaded plots, but the richness and diversity of species were not statistically different. The composition of the two invaded plots was similar to each other and more alike to that of the non-invaded plots. The species composition of the invaded plots was associated with soil potassium and phosphorus concentrations, whereas that of the non-invaded plots was more associated with soil nitrogen *** Following the removal of H. helix, several native species were registered, leading to a similar species composition as in the non-invaded plots, suggesting that some vegetation recovery can be expected following *** removal in 1 year.

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Integrating time progression in ecoimmunology studies: beyond immune response intensity

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Current Zoology 2019年第2期65卷 205-212页

作者： Francisco Javier zamora-CAMACHO Department of Biological Sciences Dartmouth College Hanover New Hampshire USA Department of Biogeography and Global Change Museo Nacional de Ciencias Naturales (MNCN) Spanish National Research Council (CSIC) Madrid Spain

Habitat alterations in agroecosystems may damage amphibian immune capacity. As agroecosystem extension is increasing worldwide, broader-context knowledge on the effects of agroecosystem stressful conditions on amphibian immune capacity is crucial for understanding and management of amphibian global declines. However, most studies on ecoimmunology assume synchronal amonggroup immune-response peaks, and focus on immune response after standardized time lapses, neglecting its progress!on. Herein, I compared inflamatory response short-term progression of agro ecosystem and n atural-habitat female and male n atterjack toads Epi da lea calamita, by measuri ng swelling response, once per hour, 6 h following an artificial immune challenge with innocuous antigen phytohemagglutinin. I also compared maximum magnitude of swelling response, irrespective of the moment when it was reached. Habitat differences arose only 3 h after challenge, when naturalhabitat toads showed greater swelling response. Maximum magnitude of swelling response was similar in toads from both habitats. However, agroecosystem toads showed a delayed swelling response as compared with natural-habitat conspecifics, probably as a consequenee of agroecosystem stressful conditions. Such a delay suggests a weaker immune capacity, and consequently impaired anti-pathogen performance. Regarding sex, swelling response magnitude did not differ between males and females. Female swelling response peaked earlier, but that of males was more sustai ned in time, which con tradicts general across-taxa fin dings that males show impaired immune response. Interestingly, results suggest that measuring swelling response only after some standardized period following stimulation may be a simplistic approach and produce unrealistic results. Consequently, studies on ecoimmunology should implement swelling response progression in order to produce unbiased science.

关键词： agroecosystem amphibian immunocompetence natural habitat immune response progressi on

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Current Zoology 2020年第5期66卷 493-503页

作者： Francesc Rubio-Gracia Emili garc.a-Berthou Helena Guasch Lluis zamora Anna Vila-Gispert Institute of Aquatic Ecology University of Girona17003 GironaSpain Integrative Freshwater Ecology Group Centre d'Tstudis Avanqats de BlanesCSIC17300 BlanesSpain

Energy metabolism fuels swimming and other biological *** compared the swimming performance and energy metabolism within and across eight freshwater fish *** swim tunnel respirometers,we measured the standard metabolic rate(SMR)and maximum metabolic rate(MMR)and calculated the critical swimming speed(Ucrit).We accounted for body size,metabolic traits,and some morphometric ratios in an effort to understand the extent and underlying causes of *** mass was largely the best predictor of swimming capacity and metabolic traits within ***,we found that predictive models using total length or SMR,in addition to body mass,signicantly in creased the explained variation of Ucrit and MMR in certain fish *** predictive models also underlined that,once body mass has been accounted for,Ucrit can be independently affected by total length or *** study exemplifies the utility of multiple regression models to assess within-species *** interspecific level,our results showed that variation in UcriX can partly be explained by the variation in the interrelated traits of MMR,finen ess,and muscle *** the species studied,bleak Al burn us alburnus performed best in terms of swimming performance and *** contrast,pumpkinseed Lepomis gibbosus showed very poor swimming performance,but attained lower mass-specific cost of transport(MCOT)than some rheophilic species,possibly reflecting a cost reduction strategy to compensate for hydrod yn amic *** con elusion,this study provides insight into the key factors in fluenci ng the swimming performa nee of fish at both intra-and in terspecific levels.

关键词： body size maximal metabolic rate morphology swimming efficiency

A System Identification-based Modeling Framework of Bidirectional DC-DC Converters for Power Grids

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Journal of Modern Power Systems and Clean Energy 2022年第3期10卷 788-799页

作者： Gabriel E.Mejia-Ruiz Mario R.A.Paternina Juan R.Rodriguez R. Juan M.Ramirez Alejandro zamora-Mendez Guillermo Bolivar-O. Department of Electrical Engineering National Autonomous University of Mexico(UNAM)Mexico CityMexico Department of Electrical Engineering Center for Research and Advanced Studies(CINVESTAV)GuadalajaraMexico Electrical Engineering Faculty Michoacan University of Saint Nicholas of Hidalgo(UMSNH)MoreliaMexico Engineering Faculty Corporacion Universitaria Minuto de Dios-UNIMINUTOBelloColombia

This paper proposes a system identification framework based on eigensystem realization to accurately model power electronic *** proposed framework affords an energy-based optimal reduction method to precisely identify the dynamics of power electronic converters from simulated or actual raw data measured at the converter’s *** method does not require any prior knowledge of the topology or internal parameters of the converter to derive the system modal *** accuracy and feasibility of the proposed method are exhaustively evaluated via simulations and practical tests on a software-simulated and hardware-implemented dual active bridge(DAB)converter under steady-state and transient *** various comparisons with the Fourier series-based generalized average model,switching model,and experimental measurements,the proposed method attains a root mean square error(RMSE)of less than 1%with respect to the actual raw ***,the computational effort is reduced to 1/8.6 of the Fourier series-based model.

关键词： Dual active bridge eigensystem realization algorithm generalized average model power electronic converter identification

Validation of Total Daily Energy Expenditure Calculated with Actiheart against Doubly Labeled Water Method in Costa Rican Schoolchildren

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Food and Nutrition Sciences 2015年第13期6卷 1193-1201页

作者： Juan diego zamora-Salas Adriana Laclé-Murray Health Research Institute University of Costa Rica San José Costa Rica

The purpose of this study was to use the measurement of the PAEE taken from Actiheart in order to calculate the TEE in Costa Rican schoolchildren, and at the same time, to determine the effectiveness when it is compared against the TEE obtained by the DLW. A total of sixteen male schoolchildren were measured for their total daily energy expenditure (TEE) with the doubly labeled water (DLW) technique. The TEE obtained by the Actiheart monitor was calculated and validated against the DWL. The TEE was obtained adding the physical activity energy expenditure given by the Actiheart, plus the basal metabolic rate, and the energy cost of growth. The Pearson’s product‐moment correlation coefficient and the paired t‐test sample were measured in order to identify the association of the data and to evidence the differences between both measurements of TEE respectively. The Lin’s concordance correlation coefficient and the Bland-Altman plot evaluated the concordance of both methods. The correlation between the TEE obtained by DLW and the one calculated by Actiheart was r = 0.97, P < 0.001. The paired t-test showed no significant differences between both methods. Lin’s concordance correlation coefficient was Cb = 0.99, classified as almost perfect. The study validated the TEE calculated with Actiheart against the TEE measured by the DLW.

关键词： Actiheart Doubly Labeled Water Energy Expenditure Isotopic Technique Schoolchildren Total Energy Expenditure

Hepatocellular carcinoma biomarkers,an imminent need

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World Journal of Gastrointestinal Oncology 2021年第11期13卷 1847-1849页

作者： S Pilar zamora-Leon Department of Preclinical Sciences Faculty of MedicineUniversidad Católica del MauleTalca 3460000Chile

Hepatocellular carcinoma(HCC)is the most common malignant neoplasm of the liver and one of the deadliest cancers *** identification of novel,highly specific and more sensitive biomarkers for HCC is crucial because exi... 详细信息

关键词： Hepatocellular carcinoma Biomarker Blood Urine Feces Gut microbiota

Single-cell system using monolithic PMUTs-on-CMos to monitor fluid hydrodynamic properties

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Microsystems & Nanoengineering 2022年第4期8卷 81-89页

作者： Eyglis Ledesma lvan zamora Jesus Yanez rantxa Uranga Nuria Barniol Department of Electronics Engineering Universitat Autonoma de Barcelona08193 BellaterraSpain

In this work,a single cell capable of monitoring fluid density,viscosity,sound velocity,and compressibility with a compact and small design is *** fluid measurement system is formed by a two-port AlScN piezoelectric micromachined ultrasonic transducer(PMUT)with an 80μm length monolithically fabricated with a 130 nm complementary metal-oxide semiconductor(CMOS)*** electrode configuration allows the entire system to be implemented in a single device,where one electrode is used as an input and the other as an *** verification was carried out by exploiting the features of piezoelectric devices such as resonators and acoustic transducers,where a frequency shift and amplitude variation are expected because of a change in density and viscosity.A sensitivity of 482±14 Hz/kg/m3 demonstrates the potential of the system compared to other dualelectrode *** addition,according to the acoustic measurement,the sound velocity,fluid compressibility,and viscosity coefficient can be extracted,which,to the best of our knowledge,is novel in these PMUT systems.

关键词： process. system electrode