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High Voltage 2021年第1期6卷 82-94页

作者： Johnatan M.rodríguez‐Serna Ricardo Albarracín‐Sánchez Department of Electrical and Electronic Engineering Automatic Controland Applied PhysicsSchool of Industrial Design and Engineering(ETSIDI)Universidad Politécnica de Madrid(UPM)MadridSpain Department of Electrical Engineering Universidad de AntioquiaMedellínColombia

Electrical trees are defects originated and driven by partial discharges(pD)activity and this is the reason why their modelling and simulation are fundamental for the ageing mechanisms comprehension and diagnosis analyses of insulation systems compound by solid *** study presents a brief review of the different models implemented to simulate pD in electrical trees inside solid *** addition,an improved deterministic model as well as a stochastic model are presented,which allow predicting adequately the pD pulses distribution,in magnitudes and phase,for non‐conducting electrical trees of different shape and *** case studies were simulated and their results exhibit good agreement when compared with measurements presented in the *** is concluded that the main parameters that state the pD behaviour in trees are the inception and extinction voltage mag-nitudes,including their probability distributions,and the tree *** models can be used for prognosis analysis based on on‐line measurements.

关键词： solid conducting electrical

Enhancement of a foaming formulation with a zwitterionic surfactant for gas mobility control in harsh reservoir conditions

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petroleum Science 2021年第5期18卷 1409-1426页

作者： Miguel Angel Roncoroni pedro Romero Jesús Montes Guido Bascialla Rosario rodríguez Ramón rodríguez pons-Esparver Luis Felipe Mazadiego María Flor García-Mayoral Universidad politécnica de Madrid MadridSpain CEpSA Research Center MadridSpain CEpSA E&p MadridSpain

This work presents the design of a robust foam formulation that tolerates harsh reservoir conditions(high salinity,high divalent ion concentration,high temperature,light oil,and hydrocarbon injection gas)in a sandstone *** this,we selected anionic Alpha Olefin Sulfonate(AOS)surfactants and studied their synergistic effects in mixtures with zwitterionic betaines to enhance foam *** laboratory workflow used to define the best formulation followed a de-risking approach in three consecutive ***,(phase 1)the main surfactant(AOS)was selected among a series of commercial candidates in static ***,(phase 2)the betaine booster to be combined with the previously selected AOS was chosen and their ratio optimized in static ***,(phase 3)the surfactant/booster ratio was optimized under dynamic conditions in a porous medium in the absence and the presence of *** a result of this study,a mixture of an AOS C14-C16 and cocamidopropyl hydroxysultaine(CApHS)was selected as the one having the best *** designed formulation was proven to be robust in a wide range of *** generated a strong and stable foam at reservoir conditions,overcoming variations in salinity and foam quality,and tolerated the presence of oil.

关键词： Gas mobility control Foam enhanced oil recovery(EOR) Foam stability High temperature high salinity reservoir Surfactant formulation

Ecosystem Services of Grazed Grasslands in the Flooding pampa

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phyton-International Journal of Experimental Botany 2024年第6期93卷 1179-1202页

作者： Elizabeth J.Jacobo Adriana M.rodríguez Facultad de Agronomía Área de AgroecologíaUniversidad de Buenos AiresBuenos Aires1417Argentina Facultad de Agronomía Departamento de Producción AnimalUniversidad de Buenos AiresBuenos Aires1417Argentina

The Flooding pampa grasslands are the last remnant of the Rio de la plata grasslands in ***-genic interventions have led to severe degradation and,as a result,the ecosystem services provided by the grass-lands are declining,in terms of provisioning,regulating,and supporting *** synthesized the existing literature on the ecosystem goods and services provided by these grasslands under grazing in different conditions and conservation *** found that plant and animal diversity and primary production are the most studied ecosystem services,while climate regulation,water supply,nutrient cycling,meat production and erosion control,in that order,are less *** services are *** grazing and glyphosate spraying are the main drivers of grassland *** grazing and conservative stocking rates have been shown to reverse degradation and demonstrate that livestock production is compatible with ecosystem conserva-tion by maintaining regulating and provisioning *** these management strategies are poorly integrated,improving their implementation will require important changes in farmers’decisions and the development of policies that create the economic conditions for this to *** is needed to understand the conditions that prevent the knowledge generated from being transferred to producers and translated into practices that would improve the provision of ecosystem services.

关键词： Salado basin sustainability biodiversity rangelands meat production adaptative multi paddock grazing process technologies agroecology

Effects of melatonin on the oxidative damage and pancreatic antioxidant defenses in ceruleininduced acute pancreatitis in rats

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Hepatobiliary & pancreatic Diseases International 2014年第4期13卷 442-446页

作者： Cristina Carrasco Ana Beatriz rodríguez José A pariente Department of physiology Neuroimmunophysiology and Chrononutrition Research Group University of Extremadura

BACKGROUND： Oxidative stress is recognized as a pivotal effector of several pathogenic processes, including acute pancreatitis. Reactive oxygen species not just cause damage on the main cellular components, but also influence the expression of antioxidant system genes. Antioxidant molecules, such as melatonin, could be good candidates for the treatment of this multidimensional disease. The present study was to evaluate the chemopreventive effect of melatonin in a rat model of ceruleininduced acute ***： Four subcutaneous injections of cerulein（20 μg/kg body weight） were given to Wistar rats at two hours intervals;melatonin was injected intraperitoneally（25 mg/kg body weight）30 minutes before each injection of cerulein. Lipid peroxidation,protein oxidation（carbonyl groups）, total antioxidant status,and glutathione peroxidase activity were determined in pancreatic tissue using commercial ***： The chemopreventive administration of melatonin caused a reduction in lipid peroxidation and protein oxidation due to injections of cerulein. Additionally, melatonin treatment was also able to revert glutathione peroxidase activity and total antioxidant status near to control levels, suggesting that melatonin could prevent from oxidative phenomena in the pancreas, such as lipid peroxidation and protein oxidation,and could stimulate, directly or indirectly, the expression of antioxidant ***： Melatonin, a polyvalent antioxidant, protected the pancreatic damage via the decrease of oxidative stress andincrease of the activities of antioxidant enzymes in ceruleininduced acute pancreatitis.

关键词： acute pancreatitis antioxidants cerulein melatonin oxidative stress

Apomorphine effects on the hippocampus

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Neural Regeneration Research 2018年第12期13卷 2064-2066页

作者： Luis Enrique Arroyo-García Antonio rodríguez-Moreno Gonzalo Flores Laboratorio de Neuropsiquiatria Instituto de Fisiologia Benemerita Universidad Autenoma de Puebla Puebla Mexico Laboratorio de Neurociencia Celular y plasticidad Universidad Pablo de Olavide Sevilla Spain

Apomorphine is a non-specific dopamine receptor agonist that has been used in the treatment of some diseases and mental disorders. Its use has particularly well documented in parkinson＇s disease（pD）. The dopaminergic agonists like apomorphine are related to oxidative processes that could induce cell damage and the functional impairment of some structures in the brain. However, most information about apomorphine in literature is focused on the improvement of the motor problems characteristic of pD, but little is known about the effects on cognitive behaviors and brain structures indirectly related to motor function. The presence of dopaminergic receptors in the hippocampus has recently been discovered, in connection with cognitive behaviors like learning and memory, these receptors are needed in neuronal plasticity. There has been a growing interest to know if this structure could be compromised by the effect of apomorphine and elucidate if part of the cognitive impairment present in the pD is due to the effect of apomorphine. In this mini-review, we summarized how apomorphine has been used since its creation, we discuss the latest information about its effect on the hippocampus and also the future perspectives to fully understand the effects of this compound.

关键词： dopamine receptor apomorphine hippocampus learning and memory plasticity dendritic length oxidative stress parkinson's disease

Digital Social Connectedness as a Lifeline for Older people: Use and Non-use of VinclesBCN During the pandemic

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International Journal of Disaster Risk Science 2024年第2期15卷 251-264页

作者： Israel rodríguez‑Giralt Daniel López‑Gómez Roser Beneito‑Montagut CareNet IN3Universitat Oberta de Catalunya08018 BarcelonaSpain School of Social Sciences Cardif UniversityCardif CF103NSWalesUK

This article presents the results of a study that evaluated VinclesBCN during COVID-19. This digital-based public social service aims to prevent loneliness and isolation in +65-year-old adults living in Barcelona. Through service user(N = 12) and professional(N = 6) interviews and a questionnaire with service users(N = 255), we demonstrate the pivotal role of digital connectedness in transforming VinclesBCN into a lifeline during the pandemic. The analysis revealed the importance of sociability, social support, and, especially, entertainment in coping with pandemic fatigue and facilitating social connectivity and support among users. Users engaged in activities such as sharing images, songs, memes, and daily greetings to provide proximity, sociability, and care among users, whether they belonged to preexisting groups or were newly introduced to the platform. It also facilitated the identification of individuals who needed companionship, comfort, or more specialized support. The findings emphasize the significance of entertainment as a resilience-building strategy during times of uncertainty. Despite the positive impact, not all users equally used the platform. Non-use was strongly associated with being a woman, having a low educational level, having preexisting social relationships, less time of enrolment in the platform, as well as a high perception of loneliness, poor self-reported health, and low mood. The article underscores the need for further research into older adults' digital engagement during crises, its role in building resilience, and advocating for inclusive digital interventions that take into account diverse older adults' needs and experiences in crisis contexts.

关键词： Barcelona COVID-19 pandemic Digital social connectedness Entertainment Older adult resilience public digital service

Determination of the ground vibration attenuation law from a singleblast: A particular case of trench blasting

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Journal of Rock Mechanics and Geotechnical Engineering 2021年第5期13卷 1182-1192页

作者： Rafael rodríguez Laura García de Marina Marc Bascompta Cristóbal Lombardía Department of Mining Exploitation and prospecting School of MiningEnergy and Materials EngineeringUniversity of OviedoIndependencia 13Oviedo33004Spain Department of Mining Industrial and ICT EngineeringPolytechnic University of Catalonia(UPC)ManresaAv.Bases de Manresa61-73Barcelona08242Spain perforaciones Noroeste S.A Longoria Carbajal No.3Oviedo33004Spain

The general transmissivity law of ground vibrations was studied,and a user-friendly methodology for determining the behavior of vibrations generated in any rock mass is *** study was based on a single blast in a trench excavation,analyzing the vibration components recorded from two fixed *** attenuation law and the main variables according to the legal requirements,frequency and peak particle velocity(ppV),are defined with this novel method,achieving a high confidence level in a simple *** proposed approach can also have an important impact in terms of reducing the potential consequences of vibrations for the surrounding construction and achieving the required definition of rock *** the cost and time in many projects where blasting techniques are applied is particularly useful for the design of future blasts.

关键词： Empirical analysis Blasting Ground vibration Trenching Wave propagation

Chitosan Nanoparticles as Biostimulant in Lettuce (Lactuca sativa L.) plants

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phyton-International Journal of Experimental Botany 2024年第4期93卷 777-787页

作者： Silvia C.Ramírez-rodríguez pablo preciado-Rangel Marcelino Cabrera-De La Fuente Susana González-Morales Hortensia Ortega-Ortiz Tecnológico Nacional de México Instituto Tecnológico de TorreónEjido AnaTorreónCoahuila27170México Departamento de Horticultura Universidad Autónoma Agraria Antonio NarroSaltillo25315México Departamento de Materiales Avanzados Centro de Investigación en Química AplicadaSaltilloCoahuila25294México

Biodegradable nanoparticles such as chitosan nanoparticles (CSNps) are used in sustainable agriculture since theyavoid damage to the environment;CSNps have positive effects such as the accumulation of bioactive compoundsand increased productivity in plants. This study aimed to investigate the impact of applying CSNps on lettuce,specifically focusing on enzymatic activity, bioactive compounds, and yield. The trial was conducted using a completelyrandomized design, incorporating CSNps: 0, 0.05, 0.1, 0.2, 0.4, and 0.8 mg mL−1. The doses of 0.4 mg mL−1improve yields up to 24.6% increases and 0.1 mg mL−1 of CSNps increases total phenols by 31.2% and antioxidantcapacity by 34.6%. In addition, when low concentrations of CSNps (0.05 and 0.1 mg L−1) were applied, anincrease in catalase was determined. The CSNps represent a good alternative to be used as a biostimulant in sustainableagriculture because they improve the yield and quality of lettuce by increasing the bioactive compounds.

关键词： Biostimulant bioactive compounds enzymatic activity

New insights into Wnt signaling alterations in amyotrophic lateral sclerosis: a potential therapeutic target?

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Neural Regeneration Research 2020年第9期15卷 1580-1589页

作者： Carlos González-Fernández pau González Francisco Javier rodríguez Laboratory of Molecular Neurology Hospital Nacional de Parapléjicos (HNP)

Amyotrophic lateral sclerosis is a fatal neurodegenerative disorder characterized by upper and lower motor neuron degeneration, which leads to progressive paralysis of skeletal muscles and, ultimately, respiratory failure between 2–5 years after symptom onset. Unfortunately, currently accepted treatments for amyotrophic lateral sclerosis are extremely scarce and only provide modest benefit. As a consequence, a great effort is being done by the scientific community in order to achieve a better understanding of the different molecular and cellular processes that influence the progression and/or outcome of this neuropathological condition and, therefore, unravel new potential targets for therapeutic intervention. Interestingly, a growing number of experimental evidences have recently shown that, besides its well-known physiological roles in the developing and adult central nervous system, the Wnt family of proteins is involved in different neuropathologica conditions, including amyotrophic lateral sclerosis. These proteins are able to modulate, at least, three different signaling pathways, usually known as canonical(β-catenin dependent) and non-canonical(β-catenin independent) signaling pathways. In the present review, we aim to provide a general overview of the current knowledge that supports the relationship between the Wnt family of proteins and its associated signaling pathways and amyotrophic lateral sclerosis pathology, as well as their possible mechanisms of action. Altogether, the currently available knowledge suggests that Wnt signaling modulation might be a promising therapeutic approach to ameliorate the histopathological and functional deficits associated to amyotrophic lateral sclerosis, and thus improve the progression and outcome of this neuropathology.

关键词： ALS astrocytes Frizzled human microglia motor neuron neurodegeneration neuroinflammation spinal cord Wnt

Is the kafirin profile capable of modulating the ileal digestibility of amino acids in a soybean meal-sorghum diet fed to pigs?

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Animal Nutrition 2019年第2期5卷 124-129页

作者： Víctor A.Balderrama-pérez JoséG.Gómez-Soto Tércia C.Reis de Souza Ericka R.rodríguez Gerardo Mariscal-Landín Facultad de Estudios Superiores Cuatitlán Universidad National Autónoma de MéxicoCuautitlan54714Mexico Facultad de Cientias Naturales Universidad Autónoma de QuerétaroQuerétaro76230Mexico Centro Nacional de Investigación Disciplinaria en Fisiología y Mejoramiento Animal Instituto Nacional de Investigaciones Forestales Agrícolas y PecuariasAjuchitilan76380Mexico

The effects of kafirins on protein and amino acid ileal digestibility have not been evaluated in vivo in *** aim of this study was to determine the effects of protein profile on apparent ileal digestibility(AID)of amino acids. We used a sorghum hybrid with low tannin content(plots with different kafirin profile. Sorghum with greater content of total kafirins had less content of y-and al-kafirins and higher content of β-and a2-kafirins than that with lower content of total kafirins. Two sorghum-soybean meal(SBM) diets were formulated: 1) low kafirin(LK) content(32.2 g/kg) and 2) high kafirin(HK) content(48.1 g/kg). A control diet(maize-SBM) and a reference SBM-diet were also prepared. The reference diet was fed to all pigs following the experimental period and was used to estimate the AID of cereals by the difference method. 'T' cannulas were fixed in the distal ileum of 18 barrows(6 by treatment), divided into 2 groups of 9 pigs. The pigs were fed 2.5 times their maintenance requirement of digestible energy(110 kcal/kg BW00.75). The AID of dry matter,protein, amino acids, and energy of the experimental diets was measured;the AID of cereals(maize, LK sorghum and HK sorghum) was estimated by the difference method. The maize-SBM diet was more digestible than the sorghum-SBM diets, only with respect to valine(p profile between the diets only affected the AID of threonine(p percentage units in LK diet compared with HK diet. Regarding the AID of cereals, maize exhibited greater AID than sorghum, with respect to valine(p p parison of sorghum with LK and HK content showed that the AID of threonine and serine increased by 50.5(p percentage units(p pec:tively. The higher content of γ-kafirins in L

关键词： Amino acids Ileal digestibility Kafirin pig Sorghum