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Ophthalmological Manifestations in Chronic Hemodialyzed Patients:A 132 Cases Study in Abidjan

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Open Journal of Ophthalmology 2019年第1期9卷 9-17页

作者： Francois Xavier Kouassi Chiatse Ellalie Koman Massesse Soumahoro Alla N’goran Simeon Kra Liliane Fortunette Angelus Ouonnebo Ange-Aristide konan Kouakou Cophican Arthur Ulrich dibi Ophthalmology Department Cocody University HospitalAbidjanCote d’Ivoire Ophthalmology Department Yopougon University HospitalAbidjanCote d’Ivoire

Purpose: The aim of this study was to describe the eye signs seen in patients on chronic hemodialysis at Cocody University Hospital and the factors influencing their occurrence. Material and Methods: We carried out in the Ophthalmology Department of Cocody University Hospital a cross-sectional study over 15 months. It focused on 132 patients on chronic hemodialysis followed in the hemodialysis department of Cocody University Hospital. Results: Hypertensive nephropathy was the leading cause of chronic renal failure (58%). The most common ocular functional sign was loss of visual acuity (LVA) (38%), followed by ocular pruritus (22%). Twenty-one percent (21%) of our patients were visually impaired (MAVLC Discussion: Eye manifestations in people with chronic renal failure and on hemodialysis are variable. Several factors are involved, mainly hypertension;first and foremost is hypertension. Correction of these factors is necessary to prevent blindness.

关键词： Renal Failure Chronic Hemodialysis Eye Signs

Profile of Patients with Breast Cancer Brain Metastasis in Abidjan

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Advances in Breast Cancer Research 2018年第2期7卷 201-210页

作者： Kouame konan Yvon Kouassi Moctar Touré evrard Narcisse Seka Oumou Kimso Mudasiru Akanji Oseni Bitti Adde Odo Arsène Gaetan Kagambega Innocent Adoubi Oncology Department of the Treichville University Hospital Department of Medicine and Medical Specialties Felix Houphou-et-Boigny University Abidjan Cote d'Ivoire

Patients with breast cancer will develop brain metastases in 15% - 25% of cases. Objective: To identify the profile of patients with breast cancer brain metastasis. Method: Retrospective study over 4 years in the oncology department of Treichville Hospital. All patients with breast carcinoma who had a brain metastasis during their cancer management were included. Results: 41 cases of breast carcinoma brain metastasis were collected. Patients were older than 40 years in 78% of cases. Family history of breast cancer was found in 7% of patients. More than 80% of patients had consulted with T3 and T4 tumor masses, with 100% of cases of node involvement. The brain was the second site of metastasis. The tumors were Triple negative in 48%, Her2 positive in 36% and luminal in 16%. Brain metastases were of late onset in the majority of cases (68%). They were clinically characterized by headaches (100%), most often included in an intracranial hypertension syndrome (52%). They were multiple (60%). Therapeutically, no surgery was performed on the metastases. Three patients received whole brain radiation therapy. All patients received systemic therapy. In terms of response, 30 cases of progression were observed after treatment and 2 cases of complete response were obtained. Survival from onset of brain metastasis was of 75% at 3 months and 2% at 12 months. Patients with longer survival rates were over 40 years old with triple negative breast cancer. Conclusion: Brain metastasis from breast cancer most often occurs in a particular clinical and pathological context in our countries.

关键词： Breast Cancer Brain Metastasis Abidjan

Assessment of Two Years of Free Surgical Treatment of Cleft Lip, Palate and Alveolar (CLPA) in the Maxillofacial Surgery and Stomatology Department of the Hospital University of Treichville-Abidjan

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Open Journal of Stomatology 2023年第8期13卷 223-232页

作者： Anoumon Marguerite Reine Evelyne Anzouan-Kacou Romaric evrard Assi Yapo Jean Francois Regis Koffi Behibro Beatrice Tehoua Ettien Franck-Olivier Manoussa Seguy Emmanuel Kouadio konan Department of Stomatology and Maxillofacial Surgery Treichville University Hospital Abidjan C&ocircte d’Ivoire Department of Surgery and Specialties Faculty of Medical Sciences Felix Houphouet-Boigny University Abidjan C&ocircte d’Ivoire

Introduction: Cleft lip, palate and alveolar (CLPA) are congenital malformations of the face due to a defect in the fusion of embryonic buds during the first weeks of embryogenesis. These malformations affect the upper lip, the alveolar bone and the palate. The incidence in Africa ranges from 1/2000 to 1/500 births. Their multidisciplinary management is long and costly. Thus, the help provided by humanitarian organisations during free care campaigns is welcome. Materials and Methods: This is a retrospective descriptive study conducted from August 2014 to July 2016 in the Maxillofacial Surgery and Stomatology Department of the Treichville University Hospital in Abidjan, Côte d’Ivoire. The objective was to describe the epidemiological, clinical and therapeutic aspects of CLPA during a humanitarian campaign for free care. Results: 51 cases of CLPA were operated on. Males were involved in 54.9% of the cases, i.e. a sex ratio of 1.2. The average age of the patients at the time of the operation was 3.44 years with extremes of 3 months and 52 years. Patients with low socioeconomic status represented 84.3% of the cases. Cleft lips (31.4%) and cleft palates (33.33%) predominated. For cleft lips, unilateral forms were the most frequent (73.5%) and the left side was most often affected (59.2%). The most common surgical techniques used were MILLARD cheiloplasty for cleft lips (79.36%) and Dorrance pushback for cleft palates (78.05%). The postoperative course was simple in the majority of cases (80.47%). Patients and/or parents were satisfied with the postoperative results in over 90% of cases. Discussion: Cleft lip and palate are common. Their management by humanitarian missions through mass campaigns allows us to receive a large number of patients affected by this pathology who are treated with a high satisfaction rate. Conclusion: The characteristics of cleft lip and palate in this study are in many respects identical to those described in the literature, but with some differ

关键词： Cleft Lip and Palate Free Care Humanitarian Surgery

Treatment and Sequelae of Panfacial Fractures in the Maxillofacial Surgery and Stomatology Department of the Hospital University of Treichville-Abidjan (Cote d’Ivoire)

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Open Journal of Stomatology 2023年第12期13卷 433-441页

作者： Romaric evrard Assi Yapo Anoumon Marguerite Reine Evelyne Anzouan-Kacou Beatrice Tehoua Ettien Jean Francois Regis Koffi Behibro Franck-Olivier Manoussa Seguy Emmanuel Kouadio konan Department of Stomatology and Maxillofacial Surgery Treichville University Hospital Abidjan C&ocircte d’Ivoire Department of Surgery and Specialties Faculty of Medical Sciences Felix Houphouet-Boigny University Abidjan C&ocircte d’Ivoire

Introduction: The treatment of panfacial fractures is complex and constitutes a challenge for the maxillofacial surgeon, who, despite therapeutic progress, frequently suffers functional and aesthetic sequelae. This study aimed to describe the treatment and evaluate the functional and aesthetic sequelae of panfacial fractures in the stomatology and maxillofacial surgery department of the Treichville University Hospital. Materials and Methods: We conducted a retrospective study over a 6 years in the stomatology and maxillofacial surgery department of Treichville University Hospital. Forty-two patients with panfacial fractures were included in the study. Results: Forty-two patients were registered. The average time to osteosynthesis was 12.4 days. Nasotracheal intubation was used most often (88%), and in the majority of cases, mixed osteosynthesis combining a screwed plate and steel wire was performed (64.29%). The “Bottom-up and Outside-in” surgical sequence was the most commonly used (64.29%). All patients had at least one functional and/or cosmetic sequela after treatment. Functional sequelae were dominated by occlusal problems and aesthetic sequelae by nasal deformities. Discussion: Panfacial fractures are characterised by their complexity, presenting maxillo-facial surgeons with a therapeutic and evolutionary challenge. The quality of the initial, often multidisciplinary, management of panfacial fractures is an essential factor in both functional and aesthetic prognosis. Conclusion: The treatment of panfacial fractures, even if well managed, is sometimes a source of sequelae, requiring often complex secondary management.

关键词： Aesthetic Sequelae Functional Sequelae Management Panfacial Fracture Treatment

Metastatic(Advanced)Prostate Cancer Resistant to Castration:The Time before Resistance Development and Therapeutic Measures Undertaken in Cote d’Ivoire

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Journal of Cancer Therapy 2018年第12期9卷 955-961页

作者： Kouassi Kouame konan Yvon Toure Moctar Seka evrard Narcisse Oumou Kimso Traore Kadjatou Odo Bitti Adde Traore Asmaho Danielle Kagambega Arsene Gaetan Adoubi Innocent Oncology Department of the Treichville University Hospital AbidjanCote d’Ivoire

Objective: Contribute to improving care for prostate cancer patients in Cote d’Ivoire by identifying the average time before the development of the hormone-resistance and inherent therapeutic strategies. Patients and Method: It was a retro and prospective study over three years performed at the University Teaching Hospital of Treichville in Abidjan. 84 patients with metastatic prostate adenocarcinoma and resistant to hormone therapy were involved in the study. The analysis of clinical records enabled us to integrate different parameters in our study. Results: Our patients were relatively young (an average age of 61 years) and most of them belonged to the middle socio-economic class (50%). The resistance occurred within an average period of 9 months. The mixing of Docetaxel and Prednisone chemotherapy was the most used method of treatment (70% of cases). However, few patients (9.5%) received Abiraterone Acetate. Digestive and hematologic toxicities were noticed but they could be controlled by inherent treatment or disappear spontaneously. After nine months of treatment, 54.24% of patients who received specific treatment were alive, but high rates of mortality were observed as for patients who were only treated symptomatically. Conclusion: The relatively short average time before the development of hormone-resistance shows the aggressiveness of prostate adenocarcinoma from black Africans. The main therapeutic standard in our context remains Taxane-based chemotherapy with a good and fair tolerance.

关键词： Cancer Prostate Occurrence Time Resistance

Non-Small Cell Lung Cancer:Therapeutic and Evolutionary Aspects in Cote d’Ivoire

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Advances in Lung Cancer 2018年第1期7卷 1-8页

作者： TouréMoctar Kouassi Kouamékonan Yvon Séka evrard Narcisse TraoréKadjatou TraoréAsmaho Danielle Odo Bitti Addé Oumou Kimso Kagambega Arsène Gaetan Adoubi Innocent Oncology Department of the Treichville University Hospital AbidjanCote d’Ivoire

Non-small cell lung cancer (NSCLC) is a heterogeneous group of malignancies including squamous cell carcinoma, adenocarcinoma, bronchioloalveolar carcinoma and large cell carcinoma. They are known to be of poor prognosis, despite a better understanding of bronchial oncogenesis. This descriptive retrospective study carried out over three years (January 2013 to December 31st, 2016) at the Oncology Department of the Treichville University Hospital in Abidjan was aimed to assess the efficacy of new treatments for NSCLC in Cote d’Ivoire and to specify their benefit in terms of quality of life, comfort and overall survival. This 77 patients study, found that NSCLC, the most frequent of which is squamous cell carcinoma, occurs in relatively young subjects, smokers (91%) diagnosed at a locally advanced or metastatic stage (89%). Cisplatin base multi-drug chemotherapy was mostly used (71%). Combined all treatments, there was a significant clinical gain. However, no complete response was observed. Hematological and digestive toxicities were seen in more than 30% of cases. Overall survival was of 9 months on average. This study is an advocate to optimize primary prevention policies for a cancer with poor prognosis despite the development of new treatments such as target therapies.

关键词： Non-Small Cell Lung Cancer Treatment Evolution