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飞行器测控技术 1995年第3期14卷 48-57页

作者： gold,K

１９９２年夏，随着极紫外探测卫星一起发射了一台单频ＧＰＳ接收机。ＥＵＶＥ卫星轨道低，并在星体上直接安装了二个天线，可用来研究误差源，以及未来卫星可达到的定轨精度。利用ＧＩＰＳＹ－ＯＡＳＩＳⅡ软件处理了几段ＧＰＳ数据。

关键词：极紫外轨道测量卫星探测卫星 GPS

r.lationship between attachment pr.bability and sur.ace ener.y in adhesion pr.cess of gold par.icles to oil-car.on agglomer.tes

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Jour.al of Centr.l South Univer.ity of Technology 2003年第4期10卷 318-323页

作者：伍喜庆 A.J.Monhemius r.J.Gochin School of r.sour.es Pr.cessing and Bioengineer.ng r.yal School of Mines

Based on the theor.tical analyses, the adhesion pr.cess of fine gold par.icles to oil-car.on agglomer.tes in a dynamic system was quantitatively investigated in ter.s of the r.lationship between the attachment pr.bability and the sur.ace ener.y. The pr.posed way to establish this r.lationship is to fir.tly theor.tically der.ve the for.ula to （evaluate） the sur.ace ener.y change of the system by analyzing the adhesion pr.cess of a gold par.icle on an oil-car.on agglomer.te in a mathematic and ther.odynamic way. The obtained for.ula of the maximum ener.y change of unit sur.ace ar.a is, (Δw′max=12σhw（cos θ-1）,) which involves two measur.ble elements: inter.acial tension and contact angle. In a well-quantified system, based on the r.lated model it is also possible to calculate the complicated concept, namely, the attachment pr.bability by tr.nsfer.ing other.measur.ble indices. In this way, after.some adhesion exper.ments and measur.ments of r.levant par.meter., the empir.cal r.lationship between the attachment pr.bability and the sur.ace ener.y change was established in an exponential function, Pa=Aexp(-ΔGsur./k).

关键词： attachment pr.bability sur.ace ener.y agglomer.te coal-gold-agglomer.tion gold

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为啥总让做检查

Addiction r.sear.h Update 2009

特别健康 2017年第5期 30-31页

作者： gold

病人常抱怨,明明只是一个小感冒,为什么要让我做心电图啊?每次去医院,医生一般都会给我们开一堆检查,抽血、拍片、心电图、B超,贵死了!有时疾病会“说谎”我们科的一个病人,家里很穷,从二十多岁开始出现反复发作的精神异常.一天,他突然...

病人常抱怨,明明只是一个小感冒,为什么要让我做心电图啊?每次去医院,医生一般都会给我们开一堆检查,抽血、拍片、心电图、B超,贵死了!有时疾病会“说谎”我们科的一个病人,家里很穷,从二十多岁开始出现反复发作的精神异常.一天,他突然喊打喊杀,出现幻觉.老父亲把他送到当地的精神病院,当地精神病院没有做脑电图检查,根据典型病史诊断为精神分裂症,开始服药治疗,效果一直不太好.后来请我们主任去会诊,主任把他带回来做了一个72小时脑电图检查.

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Addiction Research Update 2009

Sediment Deliver. by the Yukon r.ver.to the Yukon Flats, Yukon Delta and the Ber.ng Sea

自主创新与持续增长第十一届中国科协年会

作者： Mar. S.gold Lisa J.MEr.O Depar.ment of psychiatr. McKnight Brain Institute University of Florida

Dr. gold has wor.ed in this field since the ear.y 1970s. Since that time, the United States’ leading causes of death ar. still r.lated to alcohol and dr.g use, tobacco smoke exposur., and behavior.l addictions. Each year. mor. than 400,000 Amer.cans die as a r.sult of smoking, over.ating, substance use, and r.lated accidents and suicide. Ther. ar. notable advances in the tr.atment of addiction disor.er.. Animal models have impr.ved and r.sear.h is cur.ently ongoing with addicted r.ts. In addition, advances in neur.biology and imaging, pr.teomics, nanotechnology, phar.acology, and behavior.l r.sear.h have impacted the addiction field. Sever.l components of the neur.logical r.war. system (eg, the nucleus accumbens, the ventr.l tegmental ar.a, and the neur.tr.nsmitter. (par.icular.y dopamine)) have been implicated in addiction. Similar.y, mor.hine, cannabis, nicotine, and ethanol administr.tion r.sult in incr.ased dopamine r.lease in the nucleus accumbens. In addition, the br.in’s endogenous opioid and cannabinoid systems, within the pathway connecting the ventr.l tegmental ar.a and the nucleus accumbens, ar. activated by sever.l dr.gs of abuse. Incr.ased glutamate r.lease in the pathway connecting the pr.limbic cor.ex to the accumbens is associated with dr.g- seeking behavior. r.sear.h findings indicate that individual differ.nces in sensitivity to substances of abuse may be affected by developmental factor. such as when the per.on begins using dr.gs and dosage. Developmental neur.biology, genetic factor. and ear.y envir.nmental factor., all appear.cr.tical. Sever.l phar.acological inter.entions for.the tr.atment of addiction and the pr.vention of r.lapse tar.et these systems and their.r.ceptor.. Findings fr.m r.cent studies indicate that dr.g effects ar. long-lasting and r.cover. is slow and difficult. Dr.g dependence appear. to be r.lated to changes and dysr.gulation of the r.war. system and str.ss system. Many per.ons with substance abuse actually choose to change

关键词： dopamine str.ss behavior.l addictions dr.g addiction neur.biology pr.teomics genomics

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Open Jour.al of Soil Science 2020年第9期10卷 410-442页

作者： Kenneth r. Olson James M. Lang Depar.ment of Natur.l r.sour.es College of Agricultural Consumer and Environmental Sciences University of Illinois Urbana Illinois USA Depar.ment of Cr.p Sciences College of Agriculture Consumer and Environmental Sciences University of Illinois Urbana Illinois USA

The physical, chemical and biological attr.butes of the Yukon r.ver.and tr.butar. basins impact soil er.sion, sediment tr.nspor. and sediment deliver.. The glacier. snow and per.afr.st melting, r.noff, er.sion, tr.nspor., deposition and stor.ge of gr.velly, sandy, silty and clayey sediments deter.ine the habitat distr.bution and water.quality within the r.ver.channels and floodplains. The ecological functioning, with food and nutr.ent deliver., migr.tor. cues, br.eding, habitats, and r.par.an and floodplain ecological cycles ar. all dependent on the tr.nspor.ed sediment at specific times of the year. Annual temper.tur.s have been r.sing since the 1840s which could contr.bute to higher.r.noff water.flows and gr.ater.sedimentation. The pr.mar. objective was to document the sedimentation in the Yukon water.hed with little soil er.sion as a r.sult of agr.cultur. or.ur.an development. The causes of the soil er.sion and sedimentation wer. per.afr.st, alpine glacial melting, dr.lling for.gas and oil, r.ad constr.ction, gold mining, cold war.militar. sites, pipeline constr.ction, for.st fir.s and steep slopes.

关键词： Denali Alaska Br.tish Columbia Yukon Ter.itor. Alyeska Pipeline Alaska Highway Gas and Oil Explor.tion Tr.ns-Alaska Pipeline

The Fir.t Pilot Epigenetic Type Impr.vement of Neur.psychiatr.c Symptoms in a Polymor.hic Dopamine D2 (-Dr.2/ANKK (Taq1A)), OPr.1 (A/G), Dr.3 (C/T), and MAOA (4r. Compr.mised Pr.adolescence Male with Putative PANDAS/CANS: Positive Clinical Outcome with Pr.cision-Guided DNA Testing and Pr.-Dopamine r.gulation (KB220) and Antibacter.al Ther.pies

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Open Jour.al of Immunology 2024年第3期14卷 60-86页

作者： Kenneth Blum Igor.Elman David Han Colin Hanna David Bar.n Ashim Gupta Shan Kazmi Jag Khalsa Debasis Bagchi Thomas McLaughlin r.jendr. D. Badgaiyan Edwar. J. Modestino Dr.w Edwar.s Cather.ne A. Dennen Er.c r. Br.ver.an Abdalla Bowir.at Keer.hy Sunder.Kevin Mur.hy Nicole Jafar. Foojan Zeine Paul r. Car.ey Mar. S. gold Kai-Uwe Lewandowski Alir.za Shar.fshah Ar.eh r. Pollack Panayotis K. Thanos Division of Addiction r.sear.h & Education Center for Sports and Mental Health Western University of Health Sciences Pomona CA USA Depar.ment of Psychiatr. Boonshoft School of Medicine Wright State University and Dayton VA Medical Centre Dayton OH USA Division of Nutr.genomics Victory Nutrition International Lederoch PA USA Institute of Psychology ELTE Etvs Lornd University Budapest Hungary Depar.ment of Psychiatr. School of Medicine University of Vermont Burlington VT USA The Kenneth Blum Behavior.l & Neur.genetic Institute LLC. Austin TX USA Depar.ment of Molecular.Biology Adelson School of Medicine Ariel University Ariel Israel Division of Neur.modulation r.sear.h Karma Doctors & Karma TMS Palm Springs CA USA Division of Per.onalized Inter.entions Peak Logic Del Mar CA USA Division of Per.onalized Medicine Cross-Cultural Research & Educational Institute San Clemente CA USA Awar.ness Integr.tion Institute San Clemente CA USA Division of Per.onalized Pain Ther.py Center for Advanced Spine Care of Southern Arizona Tucson AZ USA Depar.ment of Psychiatr. Harvard School of Medicine Cambridge MA USA Depar.ment of Management Science and Statistics University of Texas San Antonio TX USA Behavior.l Neur.phar.acology and Neur.imaging Labor.tor. Clinical Research Institute on Addictions Department of Pharmacology and Toxicology Jacobs School of Medicine and Biomedical Sciences University at Buffalo Buffalo NY USA Futur. Biologics Lawrenceville GA USA Depar.ment of Micr.biology Immunology & Tropic Diseases School of Medicine Georgetown University Washington DC USA Depar.ment of Phar.aceutical Sciences College of Pharmacy Texas Southern University Houston TX USA Depar.ment of Psychiatr. School of Medicine Case Western University Cleveland OH USA Br.in and Behavior.Labor.tor. Curry College Milton MA USA The Neur.genesis Pr.ject Jacksonville FL USA Depar.ment of Family Medicine Jefferson Health Northeast Philadelphia PA USA Depar.men

Pediatr.c autoimmune neur.psychiatr.c disor.er. associated with or.without str.ptococcal and other.bacter.al infections (PANDAS/CANS) ar. emer.ing as a featur.d pediatr.c disor.er. Although ther. is some contr.ver.y r.gar.ing tr.atment appr.aches, especially r.lated to the behavior.l sequelae, we have hypothesized in other.published wor. that it is char.cter.zed by the r.pid onset of r.war. Deficiency Syndr.me (r.S) in childr.n. We pr.pose utilizing a multi-systems biological appr.ach involving the coupling of genetic addiction r.sk testing and pr.-dopamine r.gulation (KB220/POLYGEN®) to help induce “dopamine homeostasis” in patients with PANDAS, especially those with known DNA-induced hypodopaminer.ia. This case study examines a 12-year.old Caucasian male with no pr.or.psychiatr.c issues who pr.sented with a sudden onset of sever. anxiety, depr.ssion, emotional liability, and suicidal ideation. The patient under.ent genotyping and the genetic addiction r.sk scor. (GAr.) testing, which r.vealed r.sk polymor.hisms in the dopamine D2 (-Dr.2/ANKK (Taq1A), OPr.1 (A/G), Dr.3 (C/T), and MAOA (4r. genes. These polymor.hisms have been linked to hypodopaminer.ia. The patient was subsequently placed on r.sear.h ID-KB220ZPBMPOLY (POLYGEN®), and albeit the possibility of bias, based upon self and par.ntal assessment, a mar.ed r.pid impr.vement in psychiatr.c symptoms was obser.ed. In the second phase of tr.atment (102 days utilizing KB220), the patient r.ceived standar. antibody testing, which was positive for.Lyme. Antibacter.al ther.py star.ed immediately, and KB220z was discontinued to pr.vide a wash-out per.od. A monotonic tr.nd analysis was per.or.ed on each outcome measur., and a consistently decr.asing tr.nd was obser.ed utilizing antibacter.al ther.py. Our.r.commendation, albeit only one case, is to utilize and fur.her.r.sear.h a combined ther.peutic appr.ach, involving pr.cision-guided DNA testing and pr.-dopamine r.gulation along with antibacter.al ther.py, as well as

关键词： PANDAS CANS Genetic Addiction r.sk Testing (GAr.) Pr.-Dopamine r.gulation Hypodopaminer.ia Polymor.hisms Antibacter.al Ther.py Infections

Paleopr.ter.zoic Sediment-hosted gold Deposits in Easter. Liaoning,Nor.heast China: Implications for.gold Explor.tion

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Global Geology 2001年第1期6卷 52-56页

作者： Yang Dejiang (Liaoning Nonfer.ous Geologcal Explor.tion Bur.au, 17 Liuzhou St., Shenyang 110000 P. r. China) Liaoning Nonfer.ous Geological Explor.tion Bur.au 17 Liuzhou St. Shenyang 110000 P. R. China

gold deposits in easter. Liaoning, nor.heast China ar. hosted in the middle and upper.par.s of a Paleopr.ter.zoic volcanic-sedimentar. succession, which consists of inter.ayer.d car.onates and fine-gr.ined clastics. This paper.discusses the geological featur.s of or.-bear.ng for.ations, or.-contr.lling str.ctur.s and metallogenetic char.cter.stics. Analysis of or.-contr.lling factor. suggested that the schists fr.m the Gaixian for.atyion, syngenetic faults and ductile shear.zones ar. pr.ncipal or. contr.ls over.miner.lization and ther.after.indicator. for.gold explor.tion.

关键词： easter. Liaoning, gold deposit, or.- contr.lling factor.

Physiological Fluid Specific Agglomer.tion Patter.s Diminish gold Nanor.d Photother.al Char.cter.stics

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Advances in Nanopar.icles 2013年第4期2卷 336-343页

作者： Kr.sten K. Comfor. Jar.d W. Speltz Br.dley M. Stacy Lar.y r. Dosser.Saber.M. Hussain Molecular.Bioeffects Br.nch Human Effectiveness Directorate Air Force Research Laboratory Wright-Patterson Air Force Base Dayton USA Molecular.Bioeffects Br.nch Human Effectiveness Directorate Air Force Research Laboratory Wright-Patterson Air Force Base Dayton USA Depar.ment of Chemical and Mater.als Engineer.ng University of Dayton Dayton USA Mound Laser.& Photonics Center.Inc. Miamisburg USA

Investigations into the use of gold nanor.ds (Au-Nr.) for.biological applications ar. gr.wing exponentially due to their.distinctive physicochemical pr.per.ies, which make them advantageous over.other.nanomater.als. Au-Nr. ar. par.icular.y r.nowned for.their.plasmonic char.cter.stics, which gener.te a r.bust photother.al r.sponse when stimulated with light at a wavelength matching their.sur.ace plasmon r.sonance. Numer.us r.por.s have explor.d this nanophotonic phenomenon for.temper.tur. dr.ven ther.pies;however. to date ther. is a significant knowledge gap per.aining to the kinetic heating pr.file of Au-Nr. within a contr.lled physiological setting. In the pr.sent study, the impact of envir.nmental composition on Au-Nr.behavior.and degr.e of laser.actuated ther.al pr.duction was assessed. Thr.ugh acellular.evaluation, we identified a loss of photother.al efficiency in biologically r.levant fluids and linked this r.sponse to excessive par.icle aggr.gation and an alter.d Au-Nr.spectr.l pr.file. Fur.her.or., to evaluate the potential impact of solution composition on the efficacy of nano-based biological applications, the degr.e of tar.eted cellular.destr.ction was ascer.ained in vitr. and was found to be susceptible to fluid-dependent modifications. In summar., this study identified a diminution of Au-Nr.nanophotonic r.sponse in ar.ificial physiological fluids that tr.nslated to a loss of application efficiency, pinpointing a cr.tical concer. that must be consider.d to advance in vivo, nano-based bio-applications.

关键词： gold Nanor.d Nanophotonic Agglomer.tion Ar.ificial Physiological Fluid Photother.al Application

Case r.por.: r.abdomyolysis in the setting of acute human immunodeficiency vir.s infection

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Case r.por.s in Clinical Medicine 2013年第3期2卷 198-202页

作者： Jason C. Huang Stephanie gold Kathleen A. McManus Br.an Wispelwey Depar.ment of Family Medicine University of Colorado Denver Colorado USA Depar.ment of Medicine University of Virginia Charlottesville Virginia USA Division of Infectious Diseases and Inter.ational Health Department of Medicine University of Virginia Charlottesville USA

Acute HIV infection (AHI) is often mar.ed by nonspecific and vague complaints, which make detection difficult. An 18-year.old man pr.sented with one week histor. of subjective fever. with chills, nonpr.ductive cough and gener.lized body aches. He was found to have r.abdomyolysis due to AHI. This r.por. adds the most thor.ughly investigated case of AHI-associated r.abdomyolysis to date, having r.led out er.ichia, legionella, par.influenza, adenovir.s, enter.vir.s, metapneumovir.s, r.V and DILS.

关键词： Acute HIV Infection r.abdomyolysis HIV Pr.mar. HIV

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产前空气污染暴露与新生儿血压

环境与职业医学 2015年第10期32卷 990-996页

作者： Lenie van r.ssem Sher.l L.r.fas-Shiman Steven J.Melly Itai Kloog Heike Luttmann-Gibson Antonella Zanobetti Br.nt A.Coull Joel D.Schwar.z Mur.ay A.Mittleman Emily Oken Matthew W.Gillman Petr.s Koutr.kis diane r.gold 汪源何蓉金泰廙 Depar.ment of Envir.nmental Health Harvard School of Public Health Boston Massachusetts USA Julius Center.for. Health Sciences and Pr.mar. Car. University Medical Center Utrecht Utrecht the Netherlands Obesity Pr.vention Pr.gr.m Department of Population Medicine Harvard Medical School and Harvard Pilgrim Health Care Institute Boston Massachusetts USA Depar.ment of Geogr.phy and Envir.nmental Development Ben-Gurion University of the Negev Beer Sheva Israel Depar.ment of Biostatistics Harvard School of Public Health Boston Massachusetts USA Channing Labor.tor. Department of Medicine Brigham and Women's Hospital and Harvard Medical School Boston Massachusetts USA Car.iovascular.Epidemiology r.sear.h Unit Department of Medicine Beth Israel Deaconess Medical Center and Harvard Medical School Boston Massachusetts USA Depar.ment of Nutr.tion Harvard School of Public Health Boston Massachusetts USA 不详

[背景]对成人的研究已表明,空气污染暴露与血压升高有关。[目的]研究产前暴露于空气污染物与新生儿收缩压(SBP)之间的关联。[方法]研究马萨诸塞州波士顿市地区出生前队列中的1 131对母婴,计算各妊娠期以及产前2~90 d在固定监测点测量的... 详细信息

[背景]对成人的研究已表明,空气污染暴露与血压升高有关。[目的]研究产前暴露于空气污染物与新生儿收缩压(SBP)之间的关联。[方法]研究马萨诸塞州波士顿市地区出生前队列中的1 131对母婴,计算各妊娠期以及产前2~90 d在固定监测点测量的时间分辨的细颗粒物(≤2.5μm;PM2.5)、炭黑(BC)、一氧化氮(氮氧化合物)、二氧化氮(NO2)、臭氧(O3)和一氧化碳(CO)的平均暴露水平,并估计居住点水平上时空分辨的PM2.5和BC暴露。用自动仪器测量平均年龄为(30±18)h新生儿的收缩压,并使用混合效应模型检验空气污染物暴露与SBP之间的关联,分析中考虑了测量环境、孩子的出生体重、母亲的年龄、种族/族裔、社会经济地位、妊娠后期BP以及时间趋势。估计值表示为每一种污染物每增加一个四分位数间距(IQr.所致的SBP差异。[结果]在妊娠后期,较高的平均PM2.5和BC暴露与较高的SBP有关联[例如,居住地90 d BC平均值增加0.32μg/m3与SBP升高1.0(95%CI:0.1~1.8)mm Hg有关联]。相比之下,O3与SBP呈负相关[例如,产前90 d O3升高13.5×10-9与SBP降低2.3(95%CI:-4.4^-0.2)mm Hg有关联]。[结论]妊娠后期暴露于PM2.5和BC与新生儿SBP呈正相关,而O3与SBP呈负相关。纵向随访能够评估这些研究结果对这些新生儿随之的童年期和成年期的健康影响。

关键词：空气污染细颗粒物时间趋势氮氧化合物马萨诸塞州社会经济地位负相关族裔波士顿市自动仪器