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Stress intervention and disease in African American lupus patients: The balancing lupus experiences with stress strategies (BLESS) study

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Health 2014年第1期6卷 71-79页

作者： Edith M. Williams diane kamen Megan Penfield James C. Oates Division of Rheumatology and Immunology Department of Medicine Medical University of South Carolina Charleston USA Institute for Partnerships to Eliminate Health Disparities Arnold School of Public Health University of South Carolina Columbia USA Institutional Assessment and Compliance University of South Carolina Columbia USA University of South Carolina Charleston USA 3Institutional Assessment and Compliance University of South Carolina Columbia USA Medical Service Ralph H. Johnson VA Medical Center Charleston USA

Very little is known about the impact of psychosocial stress on underlying biological mechanisms in African American lupus patients, although African American women display the highest rates of lupus. Due to the exposure of African Americans to a unique trajectory of stressors throughout the life course, it may be critical to understand the relationship between psychosocial stress and underlying biological mechanisms that influence disease activity and pathology in this high risk group. To begin to fill this research void, an evidence-based self-management program was piloted among a cohort of African American lupus patients participating in a SLE database project at the Medical University of South Carolina (MUSC). To assess disease activity, during each clinic visit, a history is obtained, and physical examination, phlebotomy, and urine collection are performed. SLE Disease Activity Index (SLEDAI) and Systemic Lupus International Collaborating Clinics/American College of Rheumatology (SLICC/ACR) Damage Index (SDI) scores are assessed at each visit. Disease data corresponding with data collection timeframes for each participant were extracted from the MUSC SLE Database to assess the effectiveness of the program. Several differences were observed between the intervention and control groups on symptoms pertaining to lupus activity, and many of these differences had large effect sizes. Our findings can be rapidly translated into improved delivery of health care and targeted trials/interventions with relevance to health disparities, and if widely implemented, morbidities and mortality related to lupus could be drastically reduced in African-Americans.

关键词： SLE African Americans Self Management Stress Lupus Disease Activity

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An intervention to reduce psychosocial and biological indicators of stress in African American lupus patients: The balancing lupus experiences with stress strategies study

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Open Journal of Preventive Medicine 2014年第1期4卷 22-31页

作者： Edith M. Williams Megan Penfield diane kamen James C. Oates Division of Rheumatology and Immunology Department of Medicine Medical University of South Carolina Charleston USA Division of Rheumatology and Immunology Department of Medicine Medical University of South Carolina Charleston USA Medical Service Ralph H. Johnson VA Medical Center Charleston USA Institute for Partnerships to Eliminate Health Disparities Arnold School of Public Health University of South Carolina Columbia USA Institutional Assessment and Compliance University of South Carolina Columbia USA

Objective: Very little is known about the impact of psychosocial stress on African American lupus patients. Due to the exposure of African Americans to a unique trajectory of stressors throughout life, it may be critical to understand the relationship between psychosocial stress and underlying biological mechanisms that influence disease activity and pathology in this high risk group. Methods: The Balancing Lupus Experiences with Stress Strategies (BLESS) study piloted the validated “Better Choices, Better Health” Chronic Disease Self-Management Program (CDSMP) in 30 African-American lupus patients participating in the SLE Clinic Database Project at the Medical University of South Carolina (MUSC). Measures of psychosocial and biological indicators of stress were collected in all of the patients in each of the study conditions before and after intervention activities, as well as four months’ post-intervention, to assess the effectiveness of the program in reducing perceived and biological indicators of stress. Results: Participation in the workshops had large effects upon depression (d = 1.63 and d = 1.68), social/role activities limitations (d =1.15), health distress (d = 1.13 and d = 0.78), fatigue (d = 1.03), pain (d = 0.96), and lupus self-efficacy (d = 0.85). Neither the differences in cortisol or DHEA levels pre- and post-intervention were found to be significantly different between intervention participants and controls. Conclusion: The intervention workshops acted to reduce perceived stress and improve quality of life. Our findings imply that comparable, if not more significant gains in relevant health indicators are possible in African American patients when provided the opportunity to participate in CDSMP’s.

关键词： Lupus Stress African-American Self-Management

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Stress response silencing by an E3 ligase mutated in neurodegeneration

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四川生理科学杂志 2024年第1期46卷 21-21页

作者： diane L Haakonsen Department of Molecular and Cell Biology University of California at Berkeley Berkeley CA USA Howard Hughes Medical Institute University of California at Berkeley Berkeley CA USA California Institute for Quantitative Biosciences (QB3) University of California at Berkeley Berkeley CA USA Institute for Stem Cell Biology and Regenerative Medicine Stanford University School of Medicine Stanford CA USA Department of Pathology Stanford University School of Medicine Stanford CA USA

Stress response pathways detect and alleviate adverse conditions to safeguard cell and tissue homeostasis,yet their prolonged activation induces apoptosis and disrupts organismal *** stress responses are turned off at the right time and place remains poorly *** we report a ubiquitin-dependent mechanism that silences the cellular response to mitochondrial protein import stress.

关键词： homeostasis silence turned

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现在就找回你的热情

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中学生英语 2024年第17期 4-5页

作者： diane 苗淑华

在生活中,你会做很多事情。你会对你所做的一些事情感到满意,而对其他事情不那么满意。在生活中,有些事情会让你更加努力,也会有一些你不会在意的事情。当你有强烈的冲动去做生活中的某件事时,你就找到了热情所在。生活热情会使你热爱...

在生活中,你会做很多事情。你会对你所做的一些事情感到满意,而对其他事情不那么满意。在生活中,有些事情会让你更加努力,也会有一些你不会在意的事情。当你有强烈的冲动去做生活中的某件事时,你就找到了热情所在。生活热情会使你热爱生活。这就是为什么找到生活中热爱的事对你而言很重要。你要做的第一件事就是写下自己喜欢做的事情。你写下来的一定也要有你钟爱的人。仅从这一点,你就可以想起许多让你快乐的好事。这会告诉你生活中有许多你要关注的事情,生活中也有许多事会让你做得更好。

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每个人都需要放松一下

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中学生英语 2024年第13期 4-5页

作者： diane 苗淑华

在我们的日常生活中,我们会经受很多事情。我们有自己的需求和愿望,我们要努力奋斗,这样才能得到它们。我们也要工作或上学。有时候,我们没有时间停下来放松。有时候,我们没有时间去思考身边发生的事情。这一点也不好。你千万不要把自...

在我们的日常生活中,我们会经受很多事情。我们有自己的需求和愿望,我们要努力奋斗,这样才能得到它们。我们也要工作或上学。有时候,我们没有时间停下来放松。有时候,我们没有时间去思考身边发生的事情。这一点也不好。你千万不要把自己置于这种境地。这就是为什么你必须确保自己能够留出一些时间来放松。这是让你把其他事情做得更好的方法。在享受自我放松之前,你必须先找出让你感到疲惫和紧张的原因。人们说有一定的压力是好事。它会让我们更有行动力。请记住,这指的是少量压力,非常少的压力。当你发现有事情让你感到紧张焦虑时,就去放松一下吧。

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快乐生活的秘诀

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中学生英语 2024年第21期 4-5页

作者： diane 苗淑华

每天，我们都有很多事情要做。我们工作，我们学习，我们读书，我们写作，我们会做很多事情。但话又说回来，从长远来看，让我们的生活快乐，让自己休息一下，有时停下来看看花，这些都是非常重要的。简而言之，幸福的生活是很重要的。...

每天，我们都有很多事情要做。我们工作，我们学习，我们读书，我们写作，我们会做很多事情。但话又说回来，从长远来看，让我们的生活快乐，让自己休息一下，有时停下来看看花，这些都是非常重要的。简而言之，幸福的生活是很重要的。这不仅对我们有利，也有益于我们的身体健康。过上幸福生活的第一步是看看我们周围的人。你会发现有很多人爱着你。你会发现有很多朋友会支持你，家人也会支持你。

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增强现实眼镜带来社会影响

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科技纵览 2024年第1期 10-11,4页

作者： Rina diane Caballar 不详

还记得那次病毒视频通话事件吗?一名律师因为猫咪滤镜被打开而陷入困境。设身处地想象一样吧!假设和你交谈的人戴着类似的“智能”墨镜,这种眼镜可以在你不知情的情况下偷偷地在你的脸上应用猫咪滤镜,你会有什么感觉?

关键词：视频通话滤镜增强现实眼镜设身处地

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Influence of Production Factors on the Physico-Chemical Characteristics of Fermented Cassava Dough and Sensory Evaluation of Attieke

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Food and Nutrition Sciences 2024年第5期15卷 361-376页

作者： Weiléko Hélène Dougba Djedjro Clément Akmel Emmanuel Aya diane Boudouin Dibi Nogbou Emmanuel Assidjo Laboratory of Industrial Processes for Environmental Synthesis and New Energies Institut National Polytechnique F&#233lix Yamoussoukro C&#244te d&#8217Ivoire Department of Agro-Food and Food Industries UFR Agriculture Fisheries Resources and Agro-Industry University of San-Pedro San-Pedro C&#244te d&#8217Ivoire

Attieke is an Ivorian semolina which obtained by fermenting, pressing and steaming cassava dough. Attieke production remains a traditional activity carried out by less literate women. However, perceived differences in measurable factors and attieke qualities require an investigation of their influence on the characteristics of the pressed dough and attieke. The aim of this study is to improve the quality of the dough in relation to that of the attieke produced. The experiment was carried out on 4 production factors, namely the type of boiled or braised ferment, the incorporation rate of the ferment between 8 and 10%, the addition of oil from 0.1 to 1% and the fermentation time from 12 to 15 hours applied to the Improved African Cassava (IAC) variety. A complete experiment design of 16 samples of fermented dough and attieke was employed. These samples underwent physic-chemical analyses for the fermented dough and sensory evaluation for the attieke. It was found that, except for titratable acidity, reducing sugar content and ash content, the physico-chemical characteristics of the dough of IAC variety were significantly influenced by all production factors and their interaction. Fermentation time significantly influences 60% of the physico-chemical characteristics of the fermented dough. The type of ferment, the oil addition and the ferment rate have a significant influence at 40% of these characteristics. At the sensory level, color, acidity and grain binding with an explained variance of 34.60% were essential for the appreciation of the attieke samples. Thus, these production factors could be considered for the improvement of the fermented dough and attieke production process.

关键词： Influence Production Fermented Dough Attieke

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软件脱碳

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科技纵览 2024年第4期 28-33,4页

作者： RINA diane CABALLAR ELIAS STEIN(图) 不详

软件可能在吞噬世界,同时也在让它升温.2023年12月,来自近200个国家和地区的代表齐聚迪拜参加《联合国气候变化框架公约》第28次缔约方大会(COP28),讨论减少排放的迫切需要.与此同时,COP28网站可持续性评分工具Ecograder的数据表明,其... 详细信息

软件可能在吞噬世界,同时也在让它升温.2023年12月,来自近200个国家和地区的代表齐聚迪拜参加《联合国气候变化框架公约》第28次缔约方大会(COP28),讨论减少排放的迫切需要.与此同时,COP28网站可持续性评分工具Ecograder的数据表明,其网站每加载一个页面会产生3.69克二氧化碳.这个数字似乎很小,但如果该网站1年的浏览量达到每月1万次,其排放量将略高于从旧金山到多伦多的单程航班的排放量.

关键词：《联合国气候变化框架公约》浏览量数据表减少排放可持续性缔约方大会二氧化碳

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Accumulation of Heavy Metals in Maga-Pouss Rice Fields (Far-North Region, Cameroon) and Transfer to Rice Grains

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Agricultural Sciences 2024年第3期15卷 311-326页

作者： diane Madomguia Gilbert Bello Basokdou Kalieu W. Appoline Isabelle Patrice Kuitekam Dongo Edouard Nya Serge Hubert Zebaze Togouet Department of Hydraulics and Water Management National Advanced School of Engineering University of Maroua Maroua Cameroon Research Center of Global Studies with Multidisciplinary Units (CREGUM) Maroua Cameroon National Laboratory of Analysis of Agricultural Inputs and Products Ministry of Agriculture and Rural Development Messa-Yaoundé Cameroon Department of Animal Physiology and Biology Faculty of Sciences University of Yaoundé I Yaoundé Cameroon

Monitoring of heavy metals contamination of agricultural products and their transfer and bioaccumulation in crops like rice has become a hot topic worldwide over the last two decades. The present study was carried out to determine the accumulation of heavy metals in rice fields and their transfer to rice grains. Soil, irrigation water and rice grains samples were gathered in Maga-Pouss, Far-North, Cameroon. Concentrations of six heavy metals (lead, cadmium, zinc, copper, iron and mercury) were evaluated by Atomic Absorption Spectrophotometer (AAS). Mercury was not detected in this study. Average concentrations of metals were in this order (in mg/kg): Fe (188.60 ± 97.06) > Pb (63.63 ± 7.11) > Cd (2.59 ± 0.29) > Zn (1.10 ± 1.05) > Cu (0.80 ± 0.73) in water and Pb (105.50 ± 31.11) > Fe (105.50 ± 31.11) > Cu (45.93 ± 14.39) > Zn (22.52 ± 6.40) > Cd (3.15 ± 0.49) in soil. Water in Maga-Pouss rice fields appears to be more harmful than the soil, notably for lead, cadmium and copper. In rice grains, heavy metals were found in this order (mg/kg): Fe (188.01 ± 82.62) > Cu (27.20 ± 0.00) > Zn (23.61 ± 12.42) > Pb (19.50 ± 19.91) > Cd (2.02 ± 1.05). The mean bioconcentration factor (BCF) of metals from soil to rice grains was in the following order: Fe (2.60) > Zn (1.05) > Cd (0.64) > Cu (0.59) > Pb (0.18). From water to rice grains, the order is: Cu (37.26) > Zn (22.49) > Cd (6.97) > Pb (2.74) > Fe (1.94). Rice field pH and electrical conductivity favored the uptake of lead, copper and cadmium by rice grains. The findings of this study will be good documentation for risk assessment, and decision-making by environmental managers in this region.

关键词： Heavy Metals Rice Field Bioconcenration Factor Maga-Pouss Accumulation

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