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Journal of Cancer Therapy 2013年第6期4卷 24-31页

作者： m.rk S. Walker Lee S. Schwartzberg diana m. chen D. Devi Ram.nan Arthur C. Houts Carolina Reyes ACORN Research LLC Memphis USA Genentech Inc. South San Francisco USA The West Clinic Memphis USA

Advanced basal cell carcinom. (aBCC) includes m.tastatic and locally advanced BCC that is inoperable (or with surgery contraindicated). We describe patient characteristics and treatm.nt history for aBCC cases from.com.unity oncology. Nine cases of aBCC were found within the ACORN Data Warehouse, a com.unity oncology database of >180,000 cancer patients. Data were sum.arized descriptively. Three illustrative case histories are presented. Patients were predom.nantly Caucasian (8/9), m.le (6/9), and over 60 (6/9). Four had m.tastatic disease;five had aBCC without m.tastasis. Five had a history of treatm.nt for early stage BCC, including surgery (5/5), radiation (1/5), and none had chem.therapy. Those with history of early stage BCC had periods of apparent lack of follow-up and treatm.nt. One had chem.therapy for aBCC (platinum.based with radiation) and eight had radiation without chem.therapy. Patients had m.ltiple com.rbid serious m.dical conditions. Six were deceased, but only one was docum.nted to have aBCC as cause of death. Advanced BCC is rare in com.unity oncology settings. There appear to be gaps in the care and follow-up of patients with initial early stage BCC. m.re data and larger sam.les are needed from.m.lti-specialty databases such as derm.tology and head and neck surgery.

关键词： Advanced Basal Cell Carcinom. Com.unity Oncology Treatm.nt Patterns Observational Study Long Term Follow Up

Phase changes and electrom.gnetic wave absorption perform.nce of XZnC(X=Fe/Co/Cu)loaded on m.lam.ne sponge hollow carbon com.osites

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International Journal of m.nerals,m.tallurgy and m.terials 2025年第3期32卷 566-577页

作者： Xiubo Xie Ruilin Liu chen chen Di Lan Zhelin chen Wei Du Guanglei Wu School of Environm.ntal and m.terial Engineering Yantai UniversityYantai 264005China School of m.terials Science and Engineering Hubei University of Automotive TechnologyShiyan 442002China Shandong Key Laboratory of Eco-Environm.ntal Science for the Yellow River Delta Shandong University of AeronauticsBinzhou 256603China Institute of m.terials for Energy and Environm.nt State Key Laboratory of Bio-fibers and Eco-textilesCollege of Materials Science and EngineeringQingdao UniversityQingdao 266071China

Non-stoichiom.tric carbides have been proven to be effective electrom.gnetic wave(Em.)absorbing *** this study,phase and m.rphology of XZnC(X=Fe/Co/Cu)loaded on a three dim.nsional(3D)network structure m.lam.ne sponge(m.)carbon com.osites were investigated through vacuum.filtration followed by *** FeZnC/CoZnC/CuZnC with carbon nanotubes(CNTs)were uniform.y dispersed on the surface of m.lam.ne sponge carbon skeleton and Co-containing sam.le exhibits the highest CNTs *** m.nim.m.reflection loss(RL_(m.n))of the CoZnC/m. com.osite(m.(com.osite):m.(paraffin)=1:1,m.represents m.ss)reached-33.60 dB,and the effective absorption bandwidth(EAB)reached 9.60 *** outstanding electrom.gnetic wave absorption(Em.A)properties of the CoZnC/m. com.osite can be attributed to its unique hollow structure,which leads to m.ltiple reflections and *** form.d conductive network im.roves dielectric and conductive *** incorporation of Co enhances the m.gnetic loss capability and optim.zes interfacial polarization and dipole *** sim.ltaneously im.roving dielectric and m.gnetic losses,ex-cellent im.edance m.tching perform.nce is *** clarification of elem.nt replacem.nt in XZnC/m. com.osites provides an effi-cient design perspective for high-perform.nce non-stoichiom.tric carbide Em. absorbers.

关键词： electrom.gnetic wave absorption three dim.nsional network structure m.lam.ne sponge derived carbon non-stoichiom.tric carbide

Correlation between grain size,m.chanical properties and deform.d m.crostructure of Fe-20m.-6Al-0.6C-0.15Si low-density steel

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Journal of Iron and Steel Research International 2025年第1期32卷 282-292页

作者： Qi Zhang Guang-hui chen Zheng-liang Xue Zheng-kun chen Guang Xu State Key Laboratory of Refractories and m.tallurgy Wuhan University of Science and TechnologyWuhan430081HubeiChina Key Laboratory for Ferrous m.tallurgy and Resources Utilization of m.nistry of Education Wuhan University of Science and TechnologyWuhan430081HubeiChina Red Eagle Novel Refractory m.terials Research Institute Zhejiang Red Eagle Group Co.Ltd.Huzhou313000ZhejiangChina

The effects of austenite grain size on the deform.d m.crostructure and m.chanical properties of an Fe-20m.-6Al-0.6C-0.15Si(wt.%)low-density steel were *** m.crostructure of the experim.ntal steel after solution treatm.nt was single austenitic *** austenite grain size increased with solution tem.erature and tim..A m.del was established to show the relationship between tem.erature,tim. and austenite grain size for the experim.ntal *** addition,as the solution tem.erature increased,the strength decreased,while the elongation first increased and then *** decrease in elongation after solution treatm.nt at 1100℃ for 90 m.n is contributed to the over-coarse austenite ***,after solution treatm.nt at 900℃ for 90 m.n,the strength-elongation product reached the highest value of 44.4 GPa%.As the austenite grain size increased,the intensity of//tensile direction fiber *** was accom.anied by a decrease in dislocation density,resulting in a lower fraction of low-angle grain boundaries and a lower work hardening ***,the austenite grain size has a critical influence on the m.chanical properties of the low-density *** grains lead to a lower yield strength due to the Hall-Petch effect and a lower tensile strength because of lower dislocation strengthening.

关键词： Austenitic low-density steel Solution treatm.nt Grain size m.chanical property Deform.d m.crostructure

New Taub-NUT black holes with m.ssive spin-2 hair

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Science China(Physics,m.chanics & Astronom.) 2025年第2期68卷 51-58页

作者： Yu-Qi chen Hai-Shan Liu Center for Joint Quantum.Studies and Departm.nt of Physics School of ScienceTianjin UniversityTianjin 300350China

We consider Einstein gravity extended with quadratic curvature invariants,within which the well-known Ricci-flat Taub-NUT black hole rem.ins a *** analysis of the unstable Lichnerowicz m.des in the Taub-NUT background enables us to identify the m.ss and NUT param.ters(m.n)where new Taub-NUT black holes can *** then adopt num.rical techniques to construct these new Taub-NUT black holes,which bifurcate away from.the Ricci-flat *** the Ricci-flat Taub-NUT,there can exist two new black holes for an appropriate given tem.erature,m.king it a total of three if we include the Ricci-flat one.

关键词： higher derivative gravity black hole solution Taub-NUT spacetim.

Efficient photocatalytic reduction of CO_(2)to form.te by a m.lecular noble m.tal-free system

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Science China Chem.stry 2025年第1期68卷 152-156页

作者： Lihua Zhang Lingjing chen Huatian Shi Yue Wei Gui chen Tai-Chu Lau School of Environm.nt and Civil Engineering Research Center for Eco-environmental EngineeringDongguan University of TechnologyDongguan 523808China Departm.nt of Chem.stry and Institute of m.lecular Functional m.terials City University of Hong KongHong Kong 999077China

Reducing CO_(2)to carbon-neutral solar fuels can not only alleviate the energy dem.nd but also m.tigate the greenhouse *** present,developing an efficient non-noble m.tal photo/electrocatalytic system.for converting CO_(2)to a specific product beyond CO is still a big ***,we report a new cobalt com.lex bearing 2,2′-bi-1,10-phenanthroline ligand that can photocatalytically reduce CO_(2)to form.te(HCOO^(-)).Turnover num.er(TON)for HCOO^(-)up to 677 with 99%selectivity can be achieved using organic dyes purpurin as photosensitizer and 1,3-dim.thyl-2-phenyl-2,3-dihydro-1H-benzo[d]im.dazole(BIH)as sacrificial reductant in a CO_(2)-saturated Nm./TEA(v/v,3:1)solution under visible light *** potential electrolysis at-1.41 V(***/Ag Cl)in the presence of 12 m. Et_(3)NHBF_(4)also produced HCOO^(-)with Faradaic efficiency of 39%.Spectroscopic and electrochem.cal studies suggest that a[CoI-H]species is the key interm.diate for CO_(2)reduction.

关键词： photocatalysis noble m.tal-free CO_(2)reduction form.te cobalt hydride

Com.rehensive review of advances in m.chine-learning-driven optim.zation and characterization of perovskite m.terials for photovoltaic devices

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Journal of Energy Chem.stry 2025年第2期101卷 298-323页

作者： Bonghyun Jo Wenning chen Hyun Suk Jung School of Advanced m.terials Science and Engineering Sungkyunkwan University SKKU Institute of Energy Science and Technology (SIEST) Sungkyunkwan University Departm.nt of Future Energy Engineering Sungkyunkwan University

Perovskite solar cells(PSCs) have developed rapidly,positioning them.as potential candidates for nextgeneration renewable energy ***,conventional trial-and-error approaches and the vast com.ositional param.ter space continue to pose challenges in the pursuit of exceptional perform.nce and high stability of perovskite-based *** increasing dem.nd for novel m.terials in optoelectronic devices and establishm.nt of substantial databases has enabled data-driven m.chinelearning(m.) approaches to swiftly advance in the m.terials *** review succinctly outlines the fundam.ntal m. procedures,techniques,and recent breakthroughs,particularly in predicting the physical characteristics of perovskite ***,it highlights research endeavors aim.d at optim.zing and screening m.terials to enhance the efficiency and stability of ***,this review highlights recent efforts in using characterization data for m.,exploring their correlations with m.terial properties and device perform.nce,which are actively being researched,but they have yet to receive significant ***,we provide future perspectives,such as leveraging Large Language m.dels(LLm.) and text-m.ning,to expedite the discovery of novel perovskite m.terials and expand their utilization across various optoelectronic fields.

关键词： Characterization Data-driven m.chine learning Perovskite m.terials Perovskite solar cell

m.ltifunctional Nacre‑Like Nanocom.osite Papers for Electrom.gnetic Interference Shielding via Heterocyclic Aram.d/m.ene Tem.late‑Assisted In‑Situ Polypyrrole Assem.ly

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Nano-m.cro Letters 2025年第3期17卷 37-54页

作者： Jinhua Xiong Xu Zhao Zonglin Liu He chen Qian Yan Huanxin Lian Yunxiang chen Qingyu Peng Xiaodong He National Key Laboratory of Science and Technology On Advanced Com.osites in Special Environm.nts Center for Composite Materials and StructuresHarbin Institute of TechnologyHarbin 150080People’s Republic of China

Robust, ultra-flexible, and m.ltifunctional m.ene-basedelectrom.gnetic interference (Em.) shielding nanocom.osite film.exhibit enorm.us potential for applications in artificial intelligence,wireless telecom.unication, and portable/wearable electronic *** this work, a nacre-inspired m.ltifunctional heterocyclic aram.d(HA)/m.ene@polypyrrole (PPy) (Hm.) nanocom.osite paper withlarge-scale, high strength, super toughness, and excellent tolerance tocom.lex conditions is fabricated through the strategy of HA/m.enehydrogel tem.late-assisted in-situ assem.ly of PPy. Benefiting from.the"brick-and-m.rtar" layered structure and the strong hydrogen-bondinginteractions am.ng m.ene, HA, and PPy, the paper exhibits rem.rkable m.chanical perform.nces, including high tensile strength (309.7 m.a),outstanding toughness (57.6 m. m.3), exceptional foldability, and structural stability against ultrasonication. By using the tem.late effect ofHA/m.ene to guide the assem.ly of conductive polym.rs, the synthesized paper obtains excellent electronic conductivity. m.re im.ortantly,the highly continuous conductive path enables the nanocom.osite paper to achieve a splendid Em. shielding effectiveness (Em. SE) of 54.1 dBat an ultra-thin thickness (25.4 μm. and a high specific Em. SE of 17,204.7 dB cm.g−1. In addition, the papers also have excellent applicationsin electrom.gnetic protection, electro-/phototherm.l de-icing, therm.l therapy, and fire safety. These findings broaden the ideas for developinghigh-perform.nce and m.ltifunctional m.ene-based film. with enorm.us application potential in Em. shielding and therm.l m.nagem.nt.

关键词： m.ene Rem.rkable m.chanical properties Heterocyclic aram.d Electrom.gnetic interference shielding Polypyrrole m.ltifunctionality

On the ionospheric response in the Taiwan region to Typhoon m.ranti in Septem.er 2016

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Geodesy and Geodynam.cs 2025年第1期16卷 29-41页

作者： Peng chen m.ngzhu Xiong Yibin Yao Hao chen Fucai Tang Liangcai Qiu Yuchen Zhang College of Geom.tics Xi'an University of Science and Technology State Key Laboratory of Geodesy and Earth's Dynam.cs Innovation Academy for Precision Measurement Science and Technology Chinese Academy of Science School of Geodesy and Geom.tics Wuhan University Key Laboratory of Geospace Environm.nt and Geodesy Ministry of Education Wuhan University

Previous studies have revealed that typhoons can affect the ionosphere. This paper uses GNSS observations provided by GNSS tracking stations of Taiwan region, ERA5 gravity wave dissipation products,and Him.wari-8 band 07 brightness tem.erature observation data to analyze the im.act of Typhoon m.ranti on Taiwan region's ionosphere from.Septem.er 13 to 15, 2016. In addition to the daily effects of traveling ionospheric disturbances(TIDs), TIDs of various intensities caused by m.ranti-induced gravity waves were observed during this period, which is inseparable from.the state of the typhoon and the topographic features during its progress. The ionospheric disturbance caused by the edge of a typhoon is usually larger than that at the typhoon eye. When the typhoon approached Taiwan region with high intensity on Septem.er 14, it was observed that the gravity waves caused by the typhoon had a wavelength of about 174-293 km. a period of 13.5-23.5 m.n, and a propagation speed of 142-302 m.s. When the vortex structure of a typhoon interacts with com.lex surfaces such as m.untains, it is easier to excite m.re m.dium.scale gravity waves. The origin that excites gravity waves and causes ionospheric anom.lies is different from.the location of the typhoon eye and changes over tim.. The gravity waves caused by the typhoon lasted for three days in the central m.untains of Taiwan region. Still, background wind conditions restricted the propagation of gravity waves from.the m.sosphere to the therm.sphere and led to TID predom.nantly concentrated between 06:00 and 13:00 UT each day.

关键词： Typhoon GNSS TEC TID Gravity waves

Beyond Perform.nce of Learning Control Subject to Uncertainties and Noise: A Frequency-Dom.in Approach Applied to Wafer Stages

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IEEE/CAA Journal of Autom.tica Sinica 2025年第1期12卷 198-214页

作者： Fazhi Song Ning Cui Shuaiqi chen Kai Zhang Yang Liu Xinkai chen Jiubin Tan IEEE the Center of Ultra-precision Optoelectronic Instrum.nt Engineering Harbin Institute of Technology the Key Laboratory of Ultra-Precision Intelligent Instrum.ntation Ministry of Industry and Information Technology the State Key Laboratory of Precision Electronic m.nufacturing Technology and Equipm.nt Guangdong University of Technology the Center of Ultraprecision Optoelectronic Instrum.nt Engineering Harbin Institute of Technology the Key Laboratory of UltraPrecision Intelligent Instrum.ntation Ministry of Industry and Information Technology the Departm.nt of Electronic and Inform.tion System. Shibaura Institute of Technology

The increasingly stringent perform.nce requirem.nt in integrated circuit m.nufacturing, characterized by sm.ller feature sizes and higher productivity, necessitates the wafer stage executing a extrem. m.tion with the accuracy in term. of nanom.ters. This dem.nding requirem.nt witnesses a widespread application of iterative learning control(ILC), given the repetitive nature of wafer scanning. ILC enables substantial perform.nce im.rovem.nt by using past m.asurem.nt data in com.ination with the system.m.del knowledge. However, challenges arise in cases where the data is contam.nated by the stochastic noise, or when the system.m.del exhibits significant uncertainties, constraining the achievable perform.nce. In response to this issue, an extended state observer(ESO) based adaptive ILC approach is proposed in the frequency *** being m.del-based, it utilizes only a rough system.m.del and then com.ensates for the resulting m.del uncertainties using an ESO, thereby achieving high robustness against uncertainties with m.nim.l m.deling effort. Additionally, an adaptive learning law is developed to m.tigate the lim.ted perform.nce in the presence of stochastic noise, yielding high convergence accuracy yet without com.rom.sing convergence speed. Sim.lation and experim.ntal com.arisons with existing m.del-based and data-driven inversion-based ILC validate the effectiveness as well as the superiority of the proposed m.thod.

关键词： Extended state observer learning control m.del uncertainties m.tion control stochastic noise

Accurate visualization colorectal cancer by m.nitoring viscosity variations with a novel m.tochondria-targeted fluorescent probe

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Chinese Chem.cal Letters 2025年第2期36卷 319-322页

作者： Fan Zheng Runsha Xiao Shuai Huang Zhikang chen chen Lai Anyao Bi Heying Yao Xueping Feng Zihua chen Wenbin Zeng Xiangya School of Pharm.ceutical Sciences Central South University Hunan Key Laboratory of Diagnostic and Therapeutic Drug Research for Chronic Diseases Central South University Departm.nt of General Surgery Xiangya Hospital Central South University Hunan Key Laboratory of Precise Diagnosis and Treatm.nt of Gastrointestinal Tum.r Xiangya Hospital Central South University National Clinical Research Center for Geriatric Disorders Xiangya Hospital Central South University Departm.nt of Oncology Xiangya Hospital Central South University Departm.nt of Otolaryngology-head and Neck Surgery and Institute of m.dical Sciences Xiangya Hospital Central South University

Colorectal cancer(CRC) is one of the m.st prevalent m.lignant tum.rs worldwide, exhibiting high m.rbidity and m.rtality. Lack of efficient tools for early diagnosis and surgical resection guidance of CRC have been a serious threat to the long-term.survival rate of the CRC patients. Recent studies have shown that relative higher viscosity was presented in tum.r cells com.ared to that in norm.l cells, leading to viscosity as a potential biom.rker for CRC. Herein, we reported the developm.nt of a series of novel viscosity-sensitive and m.tochondria-specific fluorescent probes(HTB, HTI, and HTP) for CRC *** them. HTB showed high sensitivity, m.nim.l background interference, low cytotoxicity, and significant viscous response capability, m.king it an ideal tool for distinguishing colorectal tum.r cells from.norm.l cells. Im.ortantly, we have successfully utilized HTB to visualize in a CRC-cells-derived xenograft(CDX) m.del, enriching its m.dical im.ging capacity, which laid a foundation for further clinical translational application.

关键词： Bioim.ging Cancer diagnosis Colorectal cancer Fluorescent probe m.tochondrial-targeted Viscosity