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Three-dimensional analysis of a faulted CO2 reservoir using an Eshelby-Mori-Tanaka approach to rock elastic properties and fault permeability

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Journal of Rock Mechanics and Geotechnical Engineering 2016年第6期8卷 828-845页

作者： Ba Nghiep Nguyen Zhangshuan hou George V.Last diana h.bacon Pacific Northwest National Laboratory RichlandWAUSA

This work develops a three-dimensional(3D) multiscale model to analyze a complex carbon dioxide(CO_2) faulted reservoir that includes some key geologic features of the San Andreas and nearby faults southwest of the Kimberlina *** model uses the STOMP-CO2 code for flow modeling that is coupled to the ABAQUS~ finite element package for geomechanical analysis.A 3D ABAQUS~ finite element model is developed that contains a large number of 3D solid elements with two nearly parallel faults whose damage zones and cores are discretized using the same continuum *** zones with different mineral compositions are considered:shale,sandstone,fault damaged sandstone,fault damaged shale,and fault ***' elastic properties that govern their poroelastic behavior are modeled by an Eshelby-Mori-Tanaka approach(EMTA).which can account for up to 15 mineral *** permeability of fault damage zones affected by crack density and orientations is also predicted by an EMTA formulation.A STOMP-CO2 grid that exactly maps the ABAQUS~ finite element model is built for coupled hydromechanical *** of the reservoir assuming three different crack pattern situations(including crack volume fraction and orientation) for the fault damage zones are performed to predict the potential leakage of CO_2 due to cracks that enhance the permeability of the fault damage *** results illustrate the important effect of the crack orientation on fault permeability that can lead to substantial leakage along the fault attained by the expansion of the CO_2 *** hydraulic fracture and tendency for the faults to slip are also examined and discussed in terms of stress distributions and geomechanical properties.

关键词： Carbon dioxide(CO_2) reservoir Geomechanical modeling Mineralogy homogenization Fault Leakage Slip Elastic properties

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Neuroinflammation as a therapeutic target in huntington's disease

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Neural Regeneration Research 2025年第3期20卷 817-818页

作者： Andrea Kwakowsky Thulani h.Palpagama Center for Brain Research and Department of Anatomy and Medical Imaging Faculty of Medical and Health SciencesUniversity of AucklandAucklandNew Zealand Pharmacology and Therapeutics School of MedicineGalway Neuroscience CentreUniversity of GalwayGalwayIreland

In 1872, George huntington presented his essay “On Chorea” to the Meigs and Mason Academy of Medicine and, in doing so, detailed a disease that would later bear his name. huntington's disease(hD) is a genetic, neurodegenerative disease that manifests as the loss of motor control,cognitive impairment,and mood and psychiatric changes in paents.

关键词： huntington inflammation Medicine

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Glial response in the midcingulate cortex in huntington’s disease

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Neural Regeneration Research 2025年第1期20卷 207-208页

作者： Thulani h.Palpagama Andrea Kwakowsky Center for Brain Research and Department of Anatomy and Medical Imaging Faculty of Medical and Health SciencesUniversity of AucklandAucklandNew Zealand Pharmacology and Therapeutics School of MedicineGalway Neuroscience CenterUniversity of GalwayGalwayIreland

huntington’s disease(hD)is a genetic disease characterized by the progressive degeneration of the striatum and *** can present with a variety of symptoms that can broadly be classified into motor symptoms,inclusive of choreatic movements and rigidity,mood and psychiatric symptoms,such as depression and apathy,and cognitive symptoms,such as cognitive *** causal mutation underlying hD results from an expansion of a CAG repeat sequence on the IT15 gene,resulting in the formation and accumulation of a mutant huntingtin protein.

关键词： huntington degeneration cortex

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Comparative chemical sensor for detection of chromium(Ⅵ) in aqueous solution

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Optoelectronics Letters 2025年第1期21卷 21-27页

作者： Sura h.AL-REKABI A.A.ALWAhIB Electrical Technique Department Al Suwayrah Technical Institute Middle Technical University Laser and Optoelectronics Department University of Technology-Iraq

A process for purifying aqueous solutions containing heavy and toxic metals such as chromium（Cr） has been investigated. One of the extremely harmful pollutants in rivers and seawater is the heavy metal ions due to their direct impacts on human, animals and plants are hexavalent Cr（Ⅵ）. Consequently, highly sensitive sensor to detect Cr is essential. Surface plasmon resonance（SPR） technique has attracted huge research interest in detecting heavy metals specifically. In this study, three types of prism-based SPR sensor, gold（Au）/silver（Ag）, Au/polyaniline（PANI） and Au/titanium dioxide（TiO2） nanostructured films, are investigated as potential sensing material to detect the presence of Cr（Ⅵ） ions in water. The base Au layer with thickness of 48.3 nm is deposited on a glass slide for all sensors. For Au/Ag, Au/PANI nanofibers and Au/TiO2sensor films, the Cr（Ⅵ） concentration is varied from 1 ppm to 15 ppm with sensitivity of 0.270 °ppm-1, 0.082 °ppm-1and 0.039 °ppm-1, respectively. Based on these results, the Au/PANI nanofibers are the most sensitive to Cr（Ⅵ） among the tested sensing materials.

关键词： Titanium dioxide

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Does mesenchymal stem cell’s secretome affect spinal sensory circuits?Implication for pain therapies

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Neural Regeneration Research 2025年第1期20卷 181-183页

作者： Francesco Ferrini Esri h.Juárez Adalberto Merighi Department of Veterinary Sciences University of TurinGrugliascoTOItaly Department of Psychiatry and Neuroscience UniversitéLavalQuébec CityQCCanada

Mesenchymal stem cells(MSCs)are multipotent adult stem cells of mesodermal origin that can be isolated from various tissues,including bone marrow,tooth pulp,adipose tissue,and umbilical *** have gained significant attention in regenerative medicine due to their ability to modulate the immune system and favor tissue *** enrich the medium in which they are cultivated with a broad range of bioactive molecules,including growth factors,cytokines,chemokines,enzymes,nucleic acids,and extracellular vesicles that collectively compose the MSC *** increasing number of pre-clinical studies suggest that delivering in vivo an MSC-conditioned medium(i.e.,the medium collected from MSC cultures after at least 3 days of exposure)exerts neuroprotective and anti-inflammatory effects in a variety of neurological conditions.

关键词： protective clinical collective

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Dynamic stress concentration in an infinitely long cylindrical cavity due to a point spherical source embedded within a fluid-saturated poroelastic formation of infinite extent

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Applied Mathematics and Mechanics(English Edition) 2025年第1期46卷 139-156页

作者： h.hOSSEINI O.BALILAShAKI Department of Mechanical Engineering Faculty of EngineeringGolestan University

The effects of a harmonically exciting monopole source on an infinitely long cylindrical cavity embedded entirely within a fluid-saturated poroelastic formation of infinite extent are examined theoretically. It is assumed that the source is located outside the cavity at a specified distance from the borehole axis. The magnitudes of the hoop and radial stresses beside the pore pressures exerted on the interface and inside the porous medium surrounding the borehole are calculated and discussed. Biot's poroelastic modeling along with three types of boundary conditions for the cylindrical interface including the ideal fluid, empty borehole, and rigid inclusion with a hard boundary is employed for the analysis. Utilizing a proper translational addition theorem for expressing the incident spherical wave in terms of cylindrical wave expansions, the proposed boundary conditions at the interface are satisfied. Stresses are formulated by means of wave potential functions in a three-dimensional(3D) manner. The effects of the frequency and the radial distance between the source and borehole on the induced stresses are examined for the first cylindrical modes over frequency spectra. Two permeability conditions for the interface and three types of soils for the porous formation are considered throughout the analysis. To give an overall outline of the study, a numerical example is presented. The results clearly indicate that the distance is a key parameter and has considerable effects on the induced stress values. In addition, the interface permeability condition and soil characteristics play an important role in determining the dynamic response of the borehole. Finally,the obtained results are compared with the relevant analyses existing in the literature for some limit cases, and good agreement is achieved.

关键词： Stress concentration

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在500kV线路上衰减问题的解决——变换载波频率使边相对地耦合的衰减减小

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吉林电力技术 1990年第1期5卷 71-73页

作者： John h.Nawn Gerald h.bacon 邓济宽

当费拉德尔菲亚电气公司(简称PE公司)建成了吕默利克核能电站时,它以两回500kV线路分别和威特本变电站以及比兹波顿原子能电站连接。这两回线路代替了过去连接于上述两发(变)电站的一回500kV线路。在这两段地区重让的线路上装有复用继... 详细信息

当费拉德尔菲亚电气公司(简称PE公司)建成了吕默利克核能电站时,它以两回500kV线路分别和威特本变电站以及比兹波顿原子能电站连接。这两回线路代替了过去连接于上述两发(变)电站的一回500kV线路。在这两段地区重让的线路上装有复用继电保护的新载波设备。在原线路被分开之前,通用电气公司(简称GE公司)运用于线路的中相对地(B—N)

关键词：电站线路衰减载波频率耦合

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On the electrical conductivity of alginate hydrogels

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Regenerative Biomaterials 2018年第5期5卷 293-301页

作者： Georgia Kaklamani diana Kazaryan James Bowen Fabrice Iacovella Spiros h.Anastasiadis George Deligeorgis Institute of Electronic Structure&Laser Foundation for Research&Technology HellasP.O.Box 138571110 HeraklionCreteGreece School of Engineering and Innovation The Open UniversityMilton Keynes MK76AAUK Department of Chemistry University of CreteP.O.Box 220871003 HeraklionCreteGreece

hydrogels have been extensively used in the field of biomedical applications,offering customizable natural,synthetic or hybrid materials,particularly relevant in the field of tissue *** the bioelectronics discipline,hydrogels are promising mainly as sensing platforms with or without encapsulated cells,showing great potential in healthcare and ***,to date there is little data in the literature which characterizes the electrical properties of tissue engineering materials which are relevant to *** this work,we present electrical characterization of alginate hydrogels,a natural polysaccharide,using a four-probe method similar to electrical impedance *** acquired conductance data show distinct frequency-dependent features that change as a function of alginate and crosslinker concentration reflecting ion kinetics inside the measured ***,the presence of NIh 3T3 fibroblasts encapsulated in the hydrogels matrix was found to alter the artificial tissue’s electrical *** method used provides valuable insight to the frequency-dependent electrical response of the resulting *** is hoped that the outcome of this research will be of use in the development of cell/electronic interfaces,possibly toward diagnostic biosensors and therapeutic bioelectronics.

关键词： alginate bioelectronics conductivity hydrogel polysaccharide resistance fibroblasts

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Defect production and atomic mixing by displacement cascades in Ni_3Al

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Science China(Technological Sciences) 1997年第5期40卷 553-560页

作者：高飞王天民 A.F.Calder D.J.bacon Department of Materials Science Lanzhou University Lanzhou 730000 ChinaDepartment of Materials Science Lanzhou University Lanzhou 730000 ChinaDepartment of Materials Science and EngineeringUniversity of LiverpoolLiverpool L69 3BXUKDepartment of Materials Science and EngineeringUniversity of LiverpoolLiverpool L69 3BXUK

Molecular dynamics simulations have been employed to investigate displacement cascades in Ni3Al, with energy Ep in the range from 0.15 to 10 keV. The efficiency of production of Frenkel pairs declines with the increasing cascade energy in a fashion similar to that found recently for pure metals. The antisite defects are much more numerous than the Frenkel pairs, and their production efficiency increases with the increasing cascade energy. A new empirical relationship between the defect number and damage energy is proposed, namely Ndefect = AEpm. A high proportion of the atomic mixing occurs in the ballistic phase and is larger for the Ni atoms, implying that the phenomenon is not purely a liquid-like process.

关键词： Ni3Al displacement cascades defect production atomic mixing molecular dynamics.

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作者： Simon bacon.

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