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Documentary research on social innovation in health in Latin America

Infectious Diseases of Poverty 2020年第2期9卷 92-92页

作者： diana Maria castro-arroyave Luisa Fernanda Duque-Paz Centro Internacional de Entrenamiento e Investigaciones Medicas(CIDEIM) CaliColombia Icesi University CaliColombia

Background:Identifying social innovation in health initiatives,promoting quality of life through them,and transforming current health conditions demand the knowledge,comprehension and appropriation of the theoretical and methodological developments of this concept Academic developments in social innovation have mainly occurred in and been documented for English-speaking countries,although relevant experiences have been implemented in Latin *** this article,we describe and analyze how social innovation in health is being approached and understood in this *** text:To identify the theoretical and methodological developments of social innovation in health between 2013 and 2018,a scoping review with a mixed approach was carried *** texts in English,Spanish and Portuguese were selected for a process of reflexive analysis of intra and intertextual *** approaches identified in the studied initiatives were *** most applied approaches were innovation in health,technological innovation in health and social innovation,each with twelve publications,and social innovation in health and ecohealth with ten and seven publications *** approaches showed a general interest in reaching the goals of the Sustainable Development Goals(SDGs),the Alma Ata Declaration and the Ottawa ***:The social innovation in health approach in Latin America adopts educational strategies,identifies risk factors,optimizes resources,promotes interculturality,participation,community empowerment,and enhances intersectorality and *** an approach,process,program or solution,social innovation in health is a conceptual category under *** research provides a baseline for other systematic reviews on the subject.

关键词： Community-based health Documental research Public health Social innovation in health Social change

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Integrated vector control of Chagas disease in Guatemala: a case of social innovation in health

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Infectious Diseases of Poverty 2020年第2期9卷 105-105页

作者： diana castro-arroyave Maria Carlota Monroy Maria Isabel Irurita Centro Internacional de Entrenamiento e Investigaciones Medicas CIDEIMCaliColombia Universidad Icesi CaliColombia 不详

Background:Improved access to health care and quality of services require integrated efforts and innovations,including community empowerment and participation in transformation *** disease is a neglected tropical disease that is generally controlled by insecticide *** achieve community empowerment in a health program,actions for social innovations may include:community-based research,interdisciplinary and intersectoral participation,community perception of direct benefits and participation in health or environmental *** aim of this study was to describe and analyze the processes by which an interdisciplinary team,in collaboration with communities of Comapa,Guatemala,developed an effective solution to address the risk for Chagas ***:A qualitative study involving interviews semi-structured and direct observation was conducted using a case study approach to describe and understand the community-based research and intervention process developed by researchers from the Laboratory of Applied Entomology and Parasitology of the Universidad de San Carlos of Guatemala(Laboratorio de Entomologia y Parasitologia Aplicada).Nine interviews were conducted with the investigators,innovators,members of the community in which the intervention had been *** software(version 12)was used for the emergent coding and analysis of the ***:Processes of social transformation were evident within households,and the communities that transcended the mere improvement of walls and *** social dynamics that favored the household economy and conditions of hygiene and home care that positively impacted the health of the *** describe how the integration of criteria of social innovation into a home improvement strategy for Chagas disease control,can generate processes of transformation in health by considering sociocultural conditions,encouraging dialogue between public health approaches and traditional ***

关键词： Chagas disease Community empowerment Interdisciplinarity Intersectorality Social innovation in health

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Universities as catalysts of social innovation in health systems in low-and middle-income countries: a multi-country case study

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Infectious Diseases of Poverty 2020年第4期9卷 151-151页

作者： Lindi van Niekerk Don Pascal Mathanga Noel Juban diana Maria castro-arroyave Dina Balabanova The Bertha Centre for Social Innovation and Entrepreneurship University of Cape Town Graduate School of BusinessCape TownSouth Africa London School of Hygiene and Tropical Medicine LondonUK The Special Programme for Research and Training in Tropical Medicine(TDR) GenevaSwitzerland University of Malawi College of MedicineBlantyreMalawi University of the Philippines School of MedicineManilathe Philippines Centro Internacional de Entrenamiento e Investigaciones Medicas(CIDEIM) CaliColombia ICESI University CaliColombia

Background Social innovation(SI)in health holds potential to contribute to health systems strengthening and universal health coverage(UHC).The role of universities in SI has been well described in the context of high-income *** evidence gap exits on SI in healthcare delivery in the context of low-and middle-income countries(LMICs)as well as on the engagement of universities from these *** is thus a need to build capacity for research and engagement in SI in healthcare delivery within these *** aim of this study was to examine the adoption and implementation of network of university hubs focused on SI in healthcare delivery within five countries across Africa,Asia and Latin *** objectives were to describe the model,components and implementation process of the hubs;identify the enablers and barriers experienced and draw implications that could be relevant to other LMIC universities interested in *** A case study design was adopted to study the implementation process of a network of university *** from documentation,team discussions and post-implementation surveys were collected from 2013 to 2018 and analysed with aid of a modified policy analysis ***/discussion SI university-based hubs serve as cross-disciplinary and cross-sectoral platforms,established to catalyse SI within the local health system through four core activities:research,community-building,storytelling and institutional embedding,and adhering to values of inclusion,assets,co-creation and *** were implemented as informal structures,managed by a small core team,in existing *** of hub implementation and functioning were the availability of strong in-country social networks,legitimacy attained from being part of a global network on SI in health and receiving a capacity building package in the initial *** encountered were internal institutional resistance,administrative challenges associated with university

关键词： Social innovation University Healthcare delivery Health system Low-and middle-income countries

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MARIE:One-Stage Object Detection Mechanism for Real-Time Identifying of Firearms

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Computer Modeling in Engineering & Sciences 2025年第1期142卷 279-298页

作者： diana Abi-Nader Hassan Harb Ali Jaber Ali Mansour Christophe Osswald Nour Mostafa Chamseddine Zaki Computer Science Department Faculty of SciencesLebanese UniversityBeirut146404Lebanon College of Engineering and Technology American University of the Middle EastEgaila54200Kuwait Lab-STICC CNRS UMR 6285ENSTA-BretagneBrest29200France

Security and safety remain paramount concerns for both governments and individuals *** today’s context,the frequency of crimes and terrorist attacks is alarmingly increasing,becoming increasingly intolerable to ***,there is a pressing need for swift identification of potential threats to preemptively alert law enforcement and security forces,thereby preventing potential attacks or violent *** advancements in big data analytics and deep learning have significantly enhanced the capabilities of computer vision in object detection,particularly in identifying *** paper introduces a novel automatic firearm detection surveillance system,utilizing a one-stage detection approach named MARIE(Mechanism for Realtime Identification of Firearms).MARIE incorporates the Single Shot Multibox Detector(SSD)model,which has been specifically optimized to balance the speed-accuracy trade-off critical in firearm detection *** SSD model was further refined by integrating MobileNetV2 and InceptionV2 architectures for superior feature extraction *** experimental results demonstrate that this modified SSD configuration provides highly satisfactory performance,surpassing existing methods trained on the same dataset in terms of the critical speedaccuracy *** these innovations,MARIE sets a new standard in surveillance technology,offering a robust solution to enhance public safety effectively.

关键词： Firearm and gun detection single shot multi-box detector deep learning one-stage detector MobileNet inception convolutional neural network

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Differential response of injured and healthy retinas to syngeneic and allogeneic transplantation of a clonal cell line of immortalized olfactory ensheathing glia:a double-edged sword

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Neural Regeneration Research 2025年第8期20卷 2395-2407页

作者： María Norte-Muñoz María Portela-Lomba Paloma Sobrado-Calvo diana Simón Johnny Di Pierdomenico Alejandro Gallego-Ortega Mar Pérez JoséMCabrera-Maqueda Javier Sierra Manuel Vidal-Sanz María Teresa Moreno-Flores Marta Agudo-Barriuso Grupo de Investigación Oftalmología Experimental Departamento de OftalmologíaOptometríaOtorrinolaringología y Anatomía PatológicaFacultad de MedicinaUniversidad de MurciaInstituto Murciano de Investigación Biosanitaria(IMIB)Campus de Ciencias de la SaludMurciaSpain Experimental Sciences Faculty Universidad Francisco de VitoriaPozuelo de AlarcónMadridSpain Anatomy Histology and Neuroscience DepartmentMedicine FacultyUniversidad Autónoma de MadridMadridSpain Center of Neuroimmunology Service of NeurologyLaboratory of Advanced Imaging in Neuroimmunological DiseasesHospital Clínic of BarcelonaInstitut d’Investigacions Biomèdiques August Pi i Sunyer(IDIBAPS)and Universitat de BarcelonaBarcelonaSpain Medicine Faculty Universidad Francisco de VitoriaPozuelo de AlarcónMadridSpain

Olfactory ensheathing glia promote axonal regeneration in the mammalian central nervous system,including retinal ganglion cell axonal growth through the injured optic ***,it is unknown whether olfactory ensheathing glia also have neuroprotective *** ensheathing glia express brain-derived neurotrophic factor,one of the best neuroprotectants for axotomized retinal ganglion ***,we aimed to investigate the neuroprotective capacity of olfactory ensheating glia after optic nerve *** ensheathing glia cells from an established rat immortalized clonal cell line,TEG3,were intravitreally injected in intact and axotomized retinas in syngeneic and allogeneic mode with or without microglial inhibition or immunosuppressive *** and gene expression analyses were *** bulb-derived primary olfactory ensheathing glia and TEG3 express major histocompatibility complex classⅡ*** and syngenically transplanted TEG3 cells survived in the vitreous for up to 21 days,forming an *** axotomized retinas,only the allogeneic TEG3 transplant rescued retinal ganglion cells at 7 days but not at 21 *** these retinas,microglial anatomical activation was higher than after optic nerve crush *** intact retinas,both transplants activated microglial cells and caused retinal ganglion cell death at 21 days,a loss that was higher after allotransplantation,triggered by pyroptosis and partially rescued by microglial inhibition or ***,neuroprotection of axotomized retinal ganglion cells did not improve with these *** different neuroprotective properties,different toxic effects,and different responses to microglial inhibitory treatments of olfactory ensheathing glia in the retina depending on the type of transplant highlight the importance of thorough preclinical studies to explore these variables.

关键词： cell therapy immune recognition major histocompatibility complex class II(MHCII) neuroprotection olfactory ensheathing glia retinal ganglion cells

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Comparison of lipid extraction methods for the microalgae Acutodesmus obliquus

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International Journal of Agricultural and Biological Engineering 2018年第5期11卷 211-217页

作者： diana Ximena Hurtado Claudia Lorena Garzón-castro Jhon Cortés-Romero Edisson Tello Camacho Bioprospecting and CAPSAB Research Groups Faculty of EngineeringUniversidad de La SabanaCundinamarca 53753Colombia Biosciences Doctoral Program Faculty of EngineeringUniversidad de La SabanaCundinamarca 53753Colombia Department of Electrical and Electronic Engineering Universidad Nacional de ColombiaBogotá53753Colombia

Microalgae are widely used in the pharmaceutical and energy industries,therefore the conditions for their cultivation and extraction methods play an important role in the profiling and acquisition of *** efficiency of lipid extraction from microalgae has attracted great interest from industry because of the wide variety of lipids and amounts that can be *** obliquus(Scenedesmus obliquus UTEX 393)was used in this *** was cultivated in Bold 3N medium modified with 75%nitrogen at 25℃,pH 6.8,125 r/min and a photoperiod of 18/6 h and illuminated with white light provided by a Light-Emitting Diode Surface Mount Device extensions(LED SMD)with an intensity of 1200μE/(m^(2)·s).The cells were stained with the Red Nile(RN)technique to indicate lipid *** extraction methods were compared,classical,microwave(MW),Soxhlet,and ultrasound(US),using the same solvent proportions(hexane:chloroform:methanol=1:2:3).All samples were analyzed with Fourier Transform Infrared Spectroscopy(FTIR)and Gas Chromatography coupled to Mass Spectrometry(GC-MS).The results showed:1)lipid production detected by RN was consistent with microalgal growth;2)the MW technique was the best extraction method,according to the statistical analysis through Randomized Complete Block(RCB)design and performance of 4.6%;and 3)the presence of saturated and unsaturated acids was indicated by FTIR ***-MS was able to identify palmitic and linoleic acids as the likely major constituents of the sample.

关键词： Acutodesmus obliquus lipid extraction trans-esterification Red Nile(RN)

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El “buen vivir” en America Latina

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今日中国（西文版） 2022年第8期 67-69页

作者： diana castro 不详

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Fuzzy Boundaries Between Post-Disaster Phases: The Case of L'Aquila, Italy

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International Journal of Disaster Risk Science 2016年第3期7卷 277-292页

作者： diana Contreras Department of Geoinformatics–Z_GIS University of Salzburg

A number of indices have been developed for measuring vulnerability to disasters, but little attention has been paid to recovery indices. Post-disaster periods are usually divided into four phases. The terms established by the United Nations Development Programme for post-disaster phases—relief, early recovery, recovery, and development—are used in this article. This research examines the hypothesis that the boundaries between post-disaster recovery phases are fuzzy and should be defined by the progress achieved in the recovery process, rather than by the amount of time elapsed since the event. The methodology employed involved four steps: fieldwork, mapping,identification of indicators, and assessment. The case study area was the city of L'Aquila in the Abruzzo region of central Italy, which was struck by an earthquake in April2009. For each phase of the recovery process in L'Aquila a score was calculated based on the progress observed in2016, 7 years after the earthquake. The highest score went to the early recovery phase(14 points), followed by the recovery phase(13 points), the development phase(12points), and the relief phase(4 points). The results demonstrate the possibility of defining post-disaster recovery phases in an affected area based on measuring achievements through indicators rather than defining recovery phases in terms of elapsed time after a disaster.

关键词： Disaster recovery Earthquakes Geographical information system (GIS) L’Aquila Post-disaster phases Spatial indicators

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The off-crust origin of granite batholiths

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Geoscience Frontiers 2014年第1期5卷 63-75页

作者： Antonio castro Unidad Asociada de Petrología Experimental CSIC-Universidad de Huelva.Campus El Carmen21071 Huelva Spain

Granitod batholiths of I-type features （mostly granodiorites and tonalites）, and particularly those forming the large plutonic associations of active continental margins and intracontinental collisional belts, represent the most outstanding magmatic episodes occurred in the continental crust. The origin of magmas, however, remains controversial. The application of principles from phase equilibria is crucial to understand the problem of granitoid magma generation. An adequate comparison between rock com- positions and experimental liquids has been addressed by using a projected compositional space in the plane F（Fe ＋ Mg）-Anorthite-Orthoclase. Many calc-alkaline granitoid trends can be considered cotectic liquids. Assimilation of country rocks and other not-cotectic processes are identified in the projected diagram. The identification of cotectic patterns in batholith implies high temperatures of magma segregation and fractionation （or partial melting） from an intermediate （andesitic） source. The com- parison of batholiths with lower crust granulites, in terms of major-element geochemistry, yields that both represent liquids and solid residues respectively from a common andesitic system. This is compatible with magmas being formed by melting, and eventual reaction with the peridotite mantle, of subducted mOlanges that are finally relaminated as magmas to the lower crust. Thus, the off-crust generation of granitoids batholiths constitutes a new paradigm in which important geological implica- tions can be satisfactorily explained. Geochemical features of Cordilleran-type batholiths are totally compatible with this new conception.

关键词： Batholith Granodiorite Andesite Relamination Granulite Lower crust

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Gastrointestinal problems, mechanisms and possible therapeutic directions in Gulf war illness: a mini review

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Military Medical Research 2022年第1期9卷 98-105页

作者： diana A.Kimono NYU Langone Medical Center New YorkNY 10016USA

By its nature, Gulf war illness(GWI) is multi-symptomatic and affects several organ systems in the body. Along with other symptoms, veterans who suffer from GWI commonly report chronic gastrointestinal issues such as constipation,pain, indigestion, etc. However, until recently, most attention has been focused on neurological disturbances such as cognitive impairments, chronic fatigue, and chronic pain among affected veterans. With such high prevalence of gastrointestinal problems among Gulf war(GW) veterans, it is surprising that there is little research to investigate the mechanisms behind these issues. This review summarizes all the available works on the mechanisms behind gastrointestinal problems in GWI that have been published to date in various databases. Generally, these studies,which were done in rodent models, in vitro and human cohorts propose that an altered microbiome, a reactive enteric nervous system or a leaky gut among other possible mechanisms are the major drivers of gastrointestinal problems reported in GWI. This review aims to draw attention to the gastrointestinal tract as an important player in GWI disease pathology and a potential therapeutic target.

关键词： Gulf war illness GWI Microbiome Enteric nervous system Gastrointestinal GI Leaky gut

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