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c.mplic.tions of physic.an misdiagnosis/treatment of rheumatic.fever in the United States

Advanc.s in Biosc.enc. and Biotec.nology 2013年第1期4卷 143-146页

作者： diana c. peterson Department of Biomedic.l Sc.enc.s Iowa State University Ames USA

Rheumatic.fever is an auto-immune disease c.used by exposure to Streptoc.c.us pyogenes. Over the last 50 years, reports of rheumatic.fever within the United States have diminished. The dec.ease was attributed to the advent of penic.llin in the treatment of streptoc.c.us infec.ions. We propose that c.rrent diagnostic.and treatment methodologies may adversely inc.ease the morbidity rate of rheumatic.fever within the United States. Public.tion rates and interest in rheumatic.fever has diminished over the last 30 years. Bec.use of this dec.ine, many physic.ans are only vaguely aware of the disorder. Additionally, the fear of antibiotic.resistanc. has influenc.d thec.nterofDisease c.ntrol to suggest a signific.nt dec.ease in the use of antibiotic. by physic.ans. Although extremely valid for the future health and well-being of the population, suc. polic.es must be examined for eac. individual c.se c.refully. The Americ.n Heart Assoc.ation presc.ibes long-term antibiotic.prophylaxis as the only c.rrent treatment;however literature reviews indic.te that suc. therapy is rarely used. Therefore individuals diagnosed with rheumatic.fever are not being treated. Additionally, bec.use many physic.ans are not routinely testing for streptoc.c.us or early signs of endoc.rditis, it is likely that c.ses of rheumatic.fever will inc.ease in the future, and many individuals may not be diagnosed until sever damage or morbidity oc.urs. Physic.an educ.tion and c.ear revised guidelines are nec.ssary to ensure adequate treatment of individuals with rheumatic.fever. Mis-understandings of the disease and how it should be treated by first responders (i.e. primary c.re providers and pediatric.ans) are disc.ssed.

关键词： Physic.an Guidelines Prophylaxis Antibiotic Resistanc. Penic.llin Rheumatic Heart Disease Endoc.rditis

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Blood metal c.nc.ntrations and c.rdiac.struc.ure and func.ion in total joint arthroplasty patients

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World Journal of Orthopedic. 2024年第8期15卷 773-782页

作者： Peter c.Brennan Stephanie M peterson Thomas J O'Byrne Mariana L Laporta c.dy c.Wyles Paul J Jannetto Garvan c.Kane Maria Vassilaki Hilal Maradit Kremers Department of Orthopedic.Surgery Mayo ClinicRochesterMN 55905United States Department of Quantitative Health Sc.enc.s Mayo ClinicRochesterMN 55905United States Department of Anesthesiology and Perioperative Medic.ne Mayo ClinicRochesterMN 55905United States Department of Laboratory Medic.ne and Pathology Mayo ClinicRochesterMN 55905United States Department of c.rdiovasc.lar Diseases Mayo ClinicRochesterMN 55905United States

BAc.GROUND There is c.nc.rn regarding potential long-term c.rdiotoxic.ty with systemic.distribution of metals in total joint arthroplasty(TJA)*** To determine the assoc.ation of c.mmonly used implant metals with ec.oc.rdiographic.measures in TJA *** The study c.mprised 110 TJA patients who had a rec.nt history of high c.romium,c.balt or titanium *** underwent two-dimensional,three-dimensional,Doppler and spec.le-strain transthorac.c.ec.oc.rdiography and a blood draw to measure metal *** and sex-adjusted linear and logistic.regression models were used to examine the assoc.ation of metal c.nc.ntrations(exposure)with ec.oc.rdiographic.measures(outc.me).RESULTS Higher c.balt c.nc.ntrations were assoc.ated with inc.eased left ventric.lar end-diastolic.volume(estimate 5.09;95%c.:0.02-10.17)as well as left atrial and right ventric.lar dilation,partic.larly in men but no c.anges in c.rdiac.*** titanium c.nc.ntrations were assoc.ated with a reduc.ion in left ventric.e global longitudinal strain(estimate 0.38;95%c.:0.70 to 0.06)and c.rdiac.index(estimate 0.08;95%c.,-0.15 to-0.01).c.Nc.USION Elevated c.balt and titanium c.nc.ntrations may be assoc.ated with struc.ural and func.ional c.rdiac.c.anges in some *** studies are warranted to better understand the systemic.effec.s of metals in TJA patients.

关键词： Total joint arthroplasty Metal-on-metal c.rdiotoxic.ty Heart failure Ec.oc.rdiography c.balt

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An analysis of air pollution assoc.ated with the 2023 sand and dust storms over c.ina:Aerosol properties and PM_(10) variability

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Geosc.enc. Frontiers 2024年第2期15卷 155-168页

作者： Mikalai Filonc.yk Mic.ael P.peterson Lifeng Zhang Haowen Yan Fac.lty of Geomatic. Lanzhou Jiaotong UniversityLanzhou 730070China Gansu Provinc.al Engineering Laboratory for National Geographic.State Monitoring Lanzhou 730070China Department of Geography/Geology University of Nebraska OmahaOmahaNE 68182USA

Every spring,a large part of c.ina is c.nfronted with sand and dust storms(SDS)–mainly originating in the Gobi(inc.uding c.inese and Mongolian Gobi)and Taklamakan *** Marc.-April 2023,most of northern,northwestern and northeastern c.ina was struc. by three sandstorms that affec.ed an area with more than 500 million *** this study,aerosol optic.l,mic.ophysic.l and radiative properties were studied during these SDS events using an integrated approac. that c.mbines satellite,terrestrial and re-analysis *** results showed that dusty c.nditions were observed in most areas north of the Yangtze River(c.ang Jiang)with daily average PM_(10)c.nc.ntrations exc.eding 1000 lg/m^(3) in many *** aerosol optic.l depth(AOD)at 550 nm during three SDS events exc.eded a value of 1 throughout nearly the entire northern part of the *** AERONET data obtained from the AOE_Baotou site showed a signific.nt inc.ease in total AOD and a c.rresponding dec.ease in AE during the *** single sc.ttering albedo(SSA),asymmetry parameter(ASY),real refrac.ive index(RRI)and imaginary refrac.ive index(IRI)values indic.te an abundanc. of sc.ttering c.arse-mode *** radiative forc.ng(ARF)at top of the atmosphere and at the earth’s surfac. was nearly always negative during the period and ranged from48.5 to+2.7 Wm^(-2)and from180.8 to66.6 Wm^(-2),resulting in high positive ARF values at ATM(from+63.8 to+132.3 Wm^(-2)).Eac. of these affec.s the heating of the atmosphere and c.oling on the earth’s *** atmospheric.heating rates ranged from 1.8 to 3.7 K day*** formation of these SDS mainly resulted from the passage of c.ld fronts assoc.ated with low pressure systems in the Gobi and Taklamakan deserts,c.eating c.nditions for dust to rise into the atmosphere and move further downwind.

关键词： Dust storm PM_(10) Aerosol optic.l depth Radiative forc.ng VIIRS AERONET

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The Effec. of Reac.ion Temperature, c.talyst c.nc.ntration and Alc.hol Ratio in the Produc.ion of Biodiesel from Raw and Purified c.stor Oil

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Advanc.s in c.emic.l Engineering and Sc.enc. 2024年第3期14卷 137-154页

作者： Sandile Brendon Masango peterson Thokozani Ngema Olusegun Ayodeji Olagunju Suresh Ramsuroop Department of c.emic.l Engineering Durban University of Technology Green Engineering Group-Chemical Thermodynamics Steve Biko Campus Durban South Africa Department of c.emic.l Engineering Cape Peninsula University of Technology Cape Town South Africa

In this study, a homogeneous alkaline c.talyst was used in the produc.ion of biodiesel from raw and refined c.stor oil feedstoc.. The effec. of potassium hydroxide (KOH) as a c.talyst between the two feedstoc.s, raw and refined c.stor oil was c.mpared. The transesterific.tion tec.nique was utilized in this study, aiming to investigate the effec. of different parameters, whic. inc.ude the reac.ion temperature, methanol-to-oil mole ratio, and c.talyst c.nc.ntration at a c.nstant period of 90 minutes. The result revealed the performanc. of the KOH c.talyst on raw c.stor oil yielded 98.49% FAME, whic. was higher than the refined c.stor oil whic. yielded 97.9% FAME. The optimal c.nditions obtained from refined c.stor oil were applied to raw c.stor oil bec.use of the same properties. The fuel quality of c.stor oil and produc.d biodiesel were tested for physic.c.emic.l properties.

关键词： Biodiesel Fuel Raw c.stor Oil Refined c.stor Oil Transesterific.tion Proc.ss

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Integrated Single-c.ll Multiomic.Analysis of HIV Latenc. Reversal Reveals Novel Regulators of Viral Reac.ivation

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Genomic., Proteomic. & Bioinformatic. 2024年第1期22卷 67-88页

作者： Manic.am Ashokkumar Wenwen Mei Jac.son J.peterson Yuriko Harigaya David M.Murdoc. David M.Margolis c.leb Kornfein Alex Oesterling Zhic.eng Guo c.nthia D.Rudin Yuc.ao Jiang Edward P.Browne Department of Medic.ne University of North Carolina at Chapel HillChapel HillNC 27599USA HIV c.re c.nter University of North Carolina at Chapel HillChapel HillNC 27599USA Department of Biostatistic. University of North Carolina at Chapel HillChapel HillNC 27599USA Department of Mic.obiology and Immunology University of North Carolina at Chapel HillChapel HillNC 27599USA Department of Genetic. University of North Carolina at Chapel HillChapel HillNC 27599USA Department of Medic.ne Duke UniversityDurhamNC 27708USA Department of c.mputer Sc.enc. Duke UniversityDurhamNC 27708USA Department of Statistic. Texas A&M UniversityCollege StationTX 77843USA Department of Biology Texas A&M UniversityCollege StationTX 77843USA Department of Biomedic.l Engineering Texas A&M UniversityCollege StationTX 77843USA

Despite the suc.ess of antiretroviral therapy,human immunodefic.enc. virus(HIV)c.nnot be c.red bec.use of a reservoir of latently infec.ed c.lls that evades *** understand the mec.anisms of HIV latenc.,we employed an integrated single-c.ll RNA sequenc.ng(sc.NA-seq)and single-c.ll assay for transposase-ac.essible c.romatin with sequenc.ng(sc.TAc.seq)approac. to simultaneously profile the transc.iptomic.and epigenomic.c.arac.eristic. of~125,000 latently infec.ed primary c.4^(+)T c.lls after reac.ivation using three different latenc. reversing *** expressed genes and differentially ac.essible motifs were used to examine transc.iptional pathways and transc.iption fac.or(TF)ac.ivities ac.oss the c.ll *** identified c.llular transc.ipts and TFs whose expression/ac.ivity was c.rrelated with viral reac.ivation and demonstrated that a mac.ine learning model trained on these data was 75%-79%ac.urate at predic.ing viral ***,we validated the role of two c.ndidate HIV-regulating fac.ors,FOXP1 and GATA3,in viral *** data demonstrate the power of integrated multimodal single-c.ll analysis to unc.ver novel relationships between host c.ll fac.ors and HIV latenc..

关键词： HIV latenc. reversal Primary c.4þT c.ll Single-c.ll multiomic. HIV-regulating fac.or Mac.ine learning

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c.mputer symbol c.lc.lation of invariants of three-manifolds obtained from trefoil knots

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c.inese Sc.enc. Bulletin 1997年第2期42卷 96-102页

作者： peterson c.ariya Department of Mathematic. Northwestern University Evanston IL 60208 USA

FOR Witten invariants, there have been many studies (see refs. [1—9]). Numeric.l c.mputer c.lc.lation of some Witten invariants τ_r (M) of several three-manifolds was done by Freed andGrompf and Neil. In this note, we c.lc.late _p(M, A) by c.mputer for all manifolds obtained by integral surgeries on a left trefoil knot, up to p≤13. The notations here are standard (see referenc.s [3, 6, 9]).

关键词： knot three-manifolds invariants.

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Updates on the relation of weight exc.ss and reproduc.ive func.ion in men： sleep apnea as a new area of interest

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Asian Journal of Andrology 2012年第1期14卷 77-81,176,177页

作者： Ahmad O Hammoud Douglas T c.rrell Mark Gibson c.Matthew peterson A Wayne Meikle Division of Reproduc.ive Endoc.inology and Infertility Department of Obstetrics and Gynecology University of Utah School of Medicine Salt Lake City UT 84108 USA Androiogy and IVF Laboratories Department of Surgery （Urology） and Physiology University of Utah School of Medicine Salt Lake City UT 84108 USA Endoc.inology/ Diabetes Researc. Department of Medicine University of Utah School of Medicine Salt Lake City UT 84132 USA

Obesity has a negative effec. on male reproduc.ive func.ion. It is assoc.ated with low testosterone levels and alteration in gonadotropin sec.etion. Male obesity has been linked to reduc.d male fertility. Data regarding the relation of obesity to sperm parameters are c.nflic.ing in terms of the nature and magnitude of the effec.. New areas of interest are emerging that c.n help explain the variation in study results, suc. as genetic.polymorphism and sleep apnea. Sleep disorders have been linked to altered testosterone produc.ion and hypogonadism in men. It was also c.rrelated to erec.ile dysfunc.ion. The relation of sleep disorders to male fertility and sperm parameters remains to be investigated. Men with hypogonadism and infertility should be sc.eened for sleep apnea. Treatment of obesity and sleep apnea improves testosterone levels and erec.ile func.ion.

关键词： infertility male infertility reproduc.ive func.ion sleep apnea weight exc.ss

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Regional-sc.le relationship among biologic.l soil c.usts,invasive annual grasses,and disturbanc.

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Ec.logic.l Proc.sses 2013年第1期2卷 18-25页

作者： Eric.B peterson Nevada Natural Hertage Program State of NevadaCarson CityNV 89701USA c.rent Address Trinity River Restoration Program US Bureau of ReclamationWeavervilleCA 96093USA

Introduc.ion:Sagebrush ec.systems in western North Americ. are being replac.d by the invasion of annual grasses,partic.larly Bromus *** experimental situations and in loc.lized landsc.pes,prior studies have doc.mented that biologic.l soil c.usts(bioc.usts)c.n reduc. annual grass presenc. and that bioc.usts are highly vulnerable to physic.l *** c.nservation would benefit from verific.tion of these patterms at sc.les that matter to loc.l *** study tests if these patterns appear at a regional ***:A previously c.llec.ed data set of vegetation provided sampling of bioc.ust c.ver ac.oss the Great Basin within the state of Nevada,USA Data were analyzed with non-par ametric.methods inc.uding odds ratios and generalized aditive models(GAM).Results:From a data set of 608 vegetation plots within the Great Basin ec.region,proportion of plots with high annual grass c.ver differed between sites with high versus low bioc.ust c.ver(p=0.0015).A negative relationship between annual grass c.ver and bioc.ust c.ver was c.nfirmed with GAM(p=0.009).For a model of bioc.ust c.ver,c.ttle disturbanc. was found to be an explanatory variable(pc.nc.usions:The patterns do appear at the regional sc.le,with high levels of c.ttle ac.ivity c.rresponding to low c.ver of bioc.usts,and low c.ver of bioc.usts c.rresponding to high c.ver of annual grasses.

关键词： Biologic.l soil c.usts c.yptogamic.c.ust Mic.ophytic.c.ust Great basin ec.region Sagebrush ec.system Landsc.pe ec.logy Disturbanc. c.ttle grazing Odds ratio Generalized additive models

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Global wild ric. germplasm resourc.s c.nservation allianc.:World Wild-Ric. Wiring

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Molec.lar Plant 2024年第4期17卷 516-518页

作者： Xiaoming Zheng Disna Ratnasekera Jiayu Fan Robert J.Henry Beng-Kah Song Kenneth M.Olsen Bal Krishna Joshi Maria c.leste N.Banatic.a-Hilario Tonapha Pusadee Adane Getac.ew Melaku Yeyinou Laura Estelle Loko Koukham Vilayheuang Gavers K.Oppong Samuel Aduse Poku peterson W.Wambugu Song Ge Aldo Merotto Junior Ohn Mar Aung Ramaiah Venuprasad Ajay Kohli Wenbin Zhou Qian Qian National Key Fac.lity for c.op Gene Resourc.s and Genetic.Improvement Institute of Crop SciencesChinese Academy of Agricultural SciencesBeijing 100081China Sanya National Researc. Institute of Breeding in Hainan Chinese Academy of Agricultural SciencesBeijing 100081China International Ric. Researc. Institute DAPO Box 7777Metro Manila 4031Philippines Department of Agric.ltural Biology Faculty of AgricultureUniversity of RuhunaMatara 81000Sri Lanka Yazhouwan National Laboratory No.8 Huanjin RoadYazhou DistrictSanya CityHainan Province 572024China Hainan University Haikou 570228China ARc.c.ntre of Exc.llenc. for Plant Suc.ess in Nature and Agric.lture University of QueenslandBrisbaneQLD4072Australia Sc.ool of Sc.enc. Monash University Malaysia47500 Bandar SunwaySelangor 47500Malaysia Department of Biology Washington University in St.LouisSt.LouisMO 63130-4899USA National Agric.lture Genetic.Resourc.s c.nter(Genebank) KhumaltarPO Box 3055KathmanduNepal Plant Biology Division Insttute of Biological SciencesUniversity of the Pilippines Los BanosLos BanosLaguna 4031Philippines Division of Agronomy Department of Plant and Soil SciencesFaculty of AgricultureChiang Mai UniversityChiang Mai 50200Thailand Bio and Emerging Tec.nology Institute Addis Ababa 1165Ethiopia National University of Sc.enc.s TechnologiesEngineering and Mathematics(UNSTIM)Dassa-ZouméBP 14Benin National Genebank Rice and Cash Crops Research CenterNAFRIVientiane 0605Lao PDR Plant Sc.enc.s and the Bioec.nomy Rothamsted ResearchHarpenden AL52JQUK UK Future Food Beac.n of Exc.llenc. and Sc.ool of Biosc.enc.s and University of Nottingham Nottingham LE125RDUK Department of Plant and Environmental Biology University of GhanaAccraGhana Kenya Agric.ltural and Livestoc. Researc. Organization Genetic Resources Research InstituteNairobi 00200Kenya Institute of Botany Chinese Academy of SciencesBeijing 100093China Federal University of Rio Grande do Sul UFRGSPorto Alegre 91501-970RSBrazil Department of Agric.ltur

Wild relatives of c.op are key genetic.resourc.s serving as diversity reservoirs for c.op improvement under c.anging ***(Oryza sativa)is one of the most important c.ops in the world,providing staple food for half of the world's *** ric. is thus a c.itic.l germplasm resourc. for sustained global food sec.rity,ensuring high produc.ion yields,improved quality,and stress resistanc. in the fac. of c.imate *** ric. is c.osely related to domestic.ted ric. and has a ric. genetic.diversity and exc.ptional adaptability to extreme *** has played a pivotal role in the history of ric. hybridization and has bec.me a key resourc. for ric. breeding *** identific.tion of wild-type c.toplasmic.male sterility resourc.s paved the way for the ac.ievement of the“three lines”goal in hybrid ric.,leading to a signific.nt inc.ease in ric. *** addition,the use of resistanc. alleles found in wild ric. is making ric. produc.ion more resilient to losses c.used by environmental ***,wild ric. germplasm resourc.s are threatened due to habitat destruc.ion and other anthropogenic.*** the same time,the lac. of c.ntralized distribution of wild ric. has hampered the sharing of basic.information on wild ric. resourc.s and the utilization and c.nservation of wild ric. in eac. c.untry,as well as c.llaboration among sc.entists.

关键词： germplasm breeding c.ops

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An integrated analysis of air pollution from US c.al-fired power plants

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Geosc.enc. Frontiers 2023年第2期14卷 204-216页

作者： Mikalai Filonc.yk Mic.ael P.peterson Fac.lty of Geomatic. Lanzhou Jiaotong UniversityLanzhou 730070China Gansu Provinc.al Engineering Laboratory for National Geographic.State Monitoring Lanzhou 730070China Department of Geography/Geology University of Nebraska OmahaOmahaNE 68182USA

The United States is one of the world’s leaders in elec.ric.ty produc.ion,generating about 4116 billion kWh in 2021,of whic. c.al ac.ounted for 21.8%of the *** study applies an integrated approac. using both terrestrial and satellite data to spec.fic.lly examine emissions from c.al-fired power plants and its spatial *** study also highlights the effec.iveness of government polic.es to reduc. *** was found that emission of pollutants from the c.untry’s energy sec.or has been steadily dec.ining,with annual emissions of sulfur dioxide(SO_(2))and nitrogen oxides(NOx)dec.easing from the US elec.ric.power sec.or between 1990 and 2020 by 93.4%and 84.8%,respec.ively,and c.rbon dioxide(c._(2))by 37%between 2007 and *** overall emissions from c.al-fired power plants are dec.ining,some individual plants have yet to install environmental equipment to c.ntrol *** to US government data,major emitters of SO_(2),NO_(x),and c._(2) in the US are the Martin Lake power plant in East Texas,the Labadie power plant near ***,Missouri,and the James H Miller Jr plant near Birmingham,*** study also integrates TROPOMI satellite data to detec. point emissions from individual power *** the highest levels of measured pollutants were over the c.untry’s major c.ties and areas of fossil fuel extrac.ion,TROPOMI c.uld c.early distinguish the pollution c.used by power plants in more rural *** the US has made great strides in reduc.ng emissions from c.al-fired power plants,these plants still represent a major sourc. of pollution and remain a major *** eliminating c.al as a power sourc. will be diffic.lt with the higher power demands resulting from the transition to elec.ric.automobiles.

关键词： c.al-fired power plants Emissions TROPOMI Air pollution Sulfur dioxide Nitrogen oxides

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