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人免疫球蛋白联合乙酰半胱氨酸对新生儿肺炎患儿临床症状及机体氧化应激水平的影响

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药品评价 2024年第4期21卷 489-492页

作者：高迪陈晓敏马蕊商丘市第一人民医院河南商丘476000

目的探讨人免疫球蛋白联合乙酰半胱氨酸对新生儿肺炎患儿临床症状及机体氧化应激水平的影响。方法本研究采用回顾性研究,选取商丘市第一人民医院86例新生儿肺炎(2021年1月至2023年10月),根据治疗方法不同分为试验组、对照组,各43例。两... 详细信息

目的探讨人免疫球蛋白联合乙酰半胱氨酸对新生儿肺炎患儿临床症状及机体氧化应激水平的影响。方法本研究采用回顾性研究,选取商丘市第一人民医院86例新生儿肺炎(2021年1月至2023年10月),根据治疗方法不同分为试验组、对照组,各43例。两组均给予常规治疗,在此基础上对照组给予乙酰半胱氨酸治疗,试验组给予人免疫球蛋白联合乙酰半胱氨酸治疗,连续治疗7 d。比较两组临床疗效,症状改善情况,氧化应激[晚期蛋白氧化产物(AOPP)、谷胱甘肽过氧化物酶(GSH-Px)、超氧化物歧化酶(SOD)]指标,免疫功能(CD3^(+)、CD8^(+)、CD4^(+)/CD8^(+)比值)及不良反应。结果治疗7 d后,试验组总有效率93.02%较对照组76.74%高(P0.05)。结论人免疫球蛋白联合乙酰半胱氨酸治疗新生儿肺炎效果确切,有助于改善免疫功能,减轻氧化应激,缩短康复进程,安全性高。

关键词：新生儿肺炎人免疫球蛋白乙酰半胱氨酸临床症状氧化应激

Knowledge of Cervical Cancer and HPV,and Willingness to Receive HPV Vaccination Among 20–45-Year-Old Women—Six Provinces,China,2018

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China CDC weekly 2023年第9期5卷 201-205页

作者： di gao Gengli Zhao Jiangli di Xiaosong Zhang Linhong Wang Department of Obstetrics and Gynecology Peking University First HospitalBeijingChina National Centre for Women and Children’s Health Chinese Center for Disease Control and PreventionBeijingChina National Center for Chronic and Non-Communicable disease Control and Prevention Chinese Center for Disease Control and PreventionBeijingChina

Summary What is already known about this topic?Cervical cancer is a significant public health problem with approximately 570,000 cases and 311,000 deaths occurring in 2018 *** is imperative to raise awareness of cervical cancer and human papillomavirus(HPV).What is added by this report?Compared to previous studies,this is one of the largest cross-sectional studies of cervical cancer and HPV in Chinese adult females in recent *** found that knowledge level of cervical cancer and HPV vaccine was still inadequate among women aged 20–45 years old,and the willingness to receive HPV vaccination was highly associated with knowledge *** are the implications for public health practice?Intervention programs should aim to improve awareness and knowledge about cervical cancer and HPV vaccines,primarily focusing on women of lower socio-economic status.

关键词： Cervical knowledge globally

Forest soil conservation based on eco-service provision unit method and its value in Anji County,Huzhou,Zhejiang,China

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Journal of Forestry Research 2015年第2期26卷 405-415页

作者： Biao Zhang Ji-xi gao gao-di Xie Chun-xia Lu Institute of Geographical Sciences and Natural Resources Research Chinese Academy of Science Nanjing Institute of Environmental Sciences Ministry of Environmental Protection

We propose an eco-service provision unit method for estimating the benefit and spatial differences of forests in controlling soil erosion.A total of 197 eco-service provision units were grouped on 1424.43 km2 of forest according to differences in vegetation,slope,soil,and *** amount of soil conservation and its economic value were *** forests in Anji County prevent4.08 9 105 tons of soil from eroding annually,thereby avoiding 1.36 9 104 tons of nutrient loss（on-site cost） and preventing 149 tons of nutritive elements from entering water systems（off-site cost）.From an economic perspective,the soil nutrient conservation in the forests of Anji County generated an annual benefit of 43.37 million RMB（Chinese Currency,6.20 RMB = US$1）.On average,each hectare of ecological forest contributed up to 436 RMB annually because of soil *** complexes with higher rainfall intensity,such as broadleaf forest and red soil on slope gradients [25°,contributed the highest soil conservation *** study identified and quantified the dominant contributors and magnitudes of soil conservation provided by *** information can benefit decision making regarding differentiated ecological compensation policies.

关键词： Soil erosion and conservation Eco-service provision unit(ESPU) Rainfall erosivity Soil erodibility Universal Soil Loss Equation(USLE)

Influence of zinc state on the catalyst properties of Zn/HZSM-5 zeolite in 1-hexene aromatization and cyclohexane dehydrogenation

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Chinese Journal of Chemical Engineering 2022年第3期35卷 124-134页

作者： di gao Yibo Zhi Liyuan Cao Liang Zhao Jinsen gao Chunming Xu Mingzhi Ma Pengfei Hao State Key Laboratory of Heavy Oil Processing China University of Petroleum(Beijing)Beijing 102249China Hebei Jingzhi Technology Company Limited Cangzhou 061000China

Rational design of Zn-containing HZSM-5 zeolite(Zn/HZSM-5)with high reactivity and excellent aromatization performance for olefin aromatization is crucially *** develop a new and uncomplicated method to synthesize Zn/HZSM-5(IMX/Z5)with superior aromatization performance in the *** to incipient wetness impregnation(IMP/Z5)and mechanical mixing(MIX/Z5),the asprepared IMX/Z5 presents a higher amount of surface ZnOH^(+)species(2.87%)while keeping identical bulk zinc *** a result,more surface ZnOH^(+)favor both the aromatization of 1-hexene and cyclohexane *** the two olefin aromatization pathways(hydrogen transfer and dehydrogenation),it is the first time found both the hydrogen transfer ability and the dehydrogenation ability increase linearly with the amount of surface ZnOH^(+)species while keeping identical bulk zinc *** believe that the linear relationships are essential to design next generation olefin aromatization catalysts.

关键词： Zinc state Catalyst Catalysis Hydrogen transfer Dehydrogenation Moleclar sieves

经皮骨盆前环内固定支架联合后路钢板治疗骨盆骨折

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临床骨科杂志 2024年第2期27卷 243-246页

作者：高迪杨朝晖尹芸生山西医科大学第二临床医学院山西太原030000 山西医科大学第二医院创伤骨科山西太原030000

目的探讨经皮骨盆前环内固定支架(INFIX)联合后路钢板治疗骨盆骨折的疗效。方法INFIX联合后路钢板治疗15例不稳定型骨盆前、后环骨折患者。记录手术情况、骨折复位及愈合情况、术后并发症发生情况。采用Majeed标准评价患者髋关节功能恢... 详细信息

目的探讨经皮骨盆前环内固定支架(INFIX)联合后路钢板治疗骨盆骨折的疗效。方法INFIX联合后路钢板治疗15例不稳定型骨盆前、后环骨折患者。记录手术情况、骨折复位及愈合情况、术后并发症发生情况。采用Majeed标准评价患者髋关节功能恢复情况。结果患者均获得随访,时间9~14个月。切口总长度10~14 cm,手术时间80~100 min,术中出血量60~100 ml。术后根据Matta et al标准评价骨折复位情况:优8例,良7例。术后3例发生股外侧皮神经症状,1例切口感染。术后开始部分负重时间3~12周。术后4~8周骨痂开始形成,10~20周骨折均愈合。末次随访时,完全下地行走14例,1例扶拐行走;采用Majeed标准评价患者髋关节功能恢复情况:优14例,良1例。结论INFIX联合后路钢板治疗骨盆骨折,手术简便,安全系数高,符合骨科微创医疗原则和精准医疗原则,有利于患者术后功能的恢复。

关键词：骨盆骨折经皮骨盆前环内固定支架钢板骨盆环损伤

基于改进随机森林算法的低压用户窃电行为自适应监测方法

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微型电脑应用 2024年第6期40卷 202-205,210页

作者：王骏梁东高迪董振祥高晓婧陈婧国网冀北电力有限公司北京100052 国网冀北电力有限公司张家口供电公司河北张家口075001 国网信通亿力科技有限责任公司福建福州350003

用户窃电行为频发,针对窃电后的日用电量,电压、三相电流变化监测过程困难,精度低的问题,提出基于改进随机森林算法的低压用户窃电行为自适应监测方法。利用分布式结构采集低压用户的用电信息,通过控制振荡器(CCO)与单线程单元(STA)的... 详细信息

用户窃电行为频发,针对窃电后的日用电量,电压、三相电流变化监测过程困难,精度低的问题,提出基于改进随机森林算法的低压用户窃电行为自适应监测方法。利用分布式结构采集低压用户的用电信息,通过控制振荡器(CCO)与单线程单元(STA)的相互配合,实现一天内96点电表曲线数据采集;从已采集到的用电信息中提取窃电用户的电量、电流与电压的用电曲线偏离度特征;将这些特征输入随机森林算法开始训练,经训练后获取自适应监测样本,并向随机森林算法中引入惩罚项因子,提升训练能力,使其具有自适应性,完成低压用户窃电行为的自适应监测。经实验验证,该方法能够精确采集用户的日用电量,在监测时可迅速发现用户窃电后的电压、三相电流变化,同时还可以实现多种窃电行为的监测。

关键词：改进随机森林算法低压用户窃电行为监测三相电流

Cu(OH)_(2)/CMC one-dimensional composite-nanofiber-based electrochemical sensor for aspirin detection

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Nanotechnology and Precision Engineering 2023年第2期6卷 48-56页

作者： Meng Cui Xiaohui Wang Ziang Quan Bing Xu di gao Key Laboratory of Special Functional Materials in Colleges and Universities of Jilin Province Jilin Institute of Chemical TechnologyJilin 132022China Jilin Electric Power Plant National Energy GroupJilin 132022China

Copper-based nanomaterials have been widely used in catalysis,electrodes,and other applications due to their unique electron-transfer *** this work,an efficient electrochemical sensor based on an electrode modified with one-dimensional Cu(OH)_(2)/carboxymethyl cellulose(CMC)composite nanofibers was fabricated and investigated for the detection of *** electron microscopy was employed to examine the morphological characteristics of these composite *** voltammetry and electrochemical impedance spectroscopy were used to assess the electrochemical performance of a Cu(OH)_(2)/CMC composite nanofiber-modified *** findings indicate that the modified electrode has a very high sensitivity to *** observed enhanced performance could be a result of the high surface-to-volume ratio of the composite nanofibers and their superior electron-transport characteristics,which may hasten electron transfer between aspirin and the surfaces of the modified *** detection technique also demonstrated strong selectivity for *** findings imply that the technique can be applied as a highly effective and selective approach to aspirin measurement in biological science.

关键词： Sodium carboxymethyl cellulose Cu(OH)_(2)nanofiber Electrochemical sensor Aspirin

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响应面法优化白及多糖提取工艺

海峡药学 2024年第1期36卷 30-35页

作者：高笛罗成周凯柴慧芳贵州中医药大学药学院贵州贵阳550025 中国科学院上海药物研究所上海310000

目的通过响应面法对白及多糖的水提醇沉工艺进行探究,并对最佳工艺下提取出的白及粗多糖进行分离纯化。方法以多糖产率为指标,采用响应面分析法对白及多糖水提醇沉工艺进行优化。白及多糖采用水提醇沉法进行提取,对提取温度、提取时... 详细信息

目的通过响应面法对白及多糖的水提醇沉工艺进行探究,并对最佳工艺下提取出的白及粗多糖进行分离纯化。方法以多糖产率为指标,采用响应面分析法对白及多糖水提醇沉工艺进行优化。白及多糖采用水提醇沉法进行提取,对提取温度、提取时间、料液比和提取次数4项进行单因素考察,选取提取温度(A)、提取时间(B)和料液比(C)3个影响较大因素,以白及多糖含量提取率为响应面值W,对提取白及多糖的工艺条件进行3因素3水平响应面分析。随后依次使用DEAE-650柱和Sepharose-6B柱对白及粗多糖进行分离纯化。结果白及多糖提取工艺影响因素:B>A>C,最佳提取条件为:提取温度68℃、提取时间94 min、料液比1∶14。所提取出的白及粗多糖,通过柱层析法分离纯化最终得到中性多糖组分BSP-B。结论此提取方法操作简单,多糖含量提取率较高,适用于白及多糖提取;再通过柱层析法分离纯化粗多糖,得到组分BSP-B,为后续实验研究奠定了基础。

关键词：白及多糖提取响应面工艺优化分离纯化

鞍山地区4种野菜重金属含量测定及健康风险评价

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鞍山师范学院学报 2024年第4期26卷 31-37页

作者：吴航高迪贾莲刁全平吕琳琳鞍山师范学院化学与生命科学学院辽宁鞍山114007 辽宁省天然产物活性分子开发及利用重点实验室辽宁鞍山114007 鞍山市检验检测认证中心辽宁鞍山114006

为了解鞍山地区常见野菜重金属含量水平及其食用安全性,以城市道路两侧野生的荠菜、车前草、蒲公英、中华苦荬菜为研究对象,利用火焰原子吸收光谱法测定野菜中镉(Cd)、铅(Pb)、镍(Ni)、锰(Mn)、铜(Cu)、锌(Zn)等6种重金属含量,并运用单... 详细信息

为了解鞍山地区常见野菜重金属含量水平及其食用安全性,以城市道路两侧野生的荠菜、车前草、蒲公英、中华苦荬菜为研究对象,利用火焰原子吸收光谱法测定野菜中镉(Cd)、铅(Pb)、镍(Ni)、锰(Mn)、铜(Cu)、锌(Zn)等6种重金属含量,并运用单因子污染指数法、内梅罗综合污染指数法以及靶标危害系数法对野菜可食用部位的重金属污染状况及对人群存在的健康风险进行评价.结果表明:4种野菜中6种重金属含量由多到少依次为Zn、Mn、Cu、Ni、Pb、Cd,其中,Pb、Ni含量超过食品中污染物限量标准,超标率分别为100.0%和86.1%;Zn元素接近限值.野菜可食用部位Pb含量范围为0.566~0.733 mg·kg^(-1),以荠菜最高;Ni含量范围为0.770~1.521 mg·kg^(-1),以蒲公英最高.单因子污染评价显示,野菜中的Pb和Ni为中污染或轻污染级别,Zn为轻污染;内梅罗综合污染评价显示,野菜的重金属复合污染处于轻污染级别,污染程度大小依次为蒲公英、荠菜、中华苦荬菜、车前草.野菜单一重金属靶标危害系数THQ值均小于1.0,但复合靶标危害系数TTHQ值均大于1.0,表明该区域野菜的重金属复合污染会对人体健康产生威胁,Pb是引起健康风险的主要重金属.鞍山地区城市道路两侧自然生长的野菜存在重金属复合污染情况,采摘食用对人群存在一定的健康风险.

关键词：野菜重金属污染评价健康风险食用安全性