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Epigallocatechin-3-gallate exerts antihypertensive effects and improves endothelial function in spontaneously hypertensive rats

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Asian Pacific Journal of Tropical Biomedicine 2023年第7期13卷 287-295页

作者： Yucinda YY Khor Siew-Keah Lee dharmani devi m Wei Chih Ling Department of Pre-clinical Sciences M.Kandiah Faculty of Medicine and Health SciencesUniversiti Tunku Abdul RahmanSelangorMalaysia Department of Pharmacology Faculty of MedicineUniversiti MalayaKuala LumpurMalaysia

Objective:To investigate the effect of epigallocatechin-3-gallate(EGCG)on endothelial dysfunction in spontaneously hypertensive rats(SHR).methods:Wistar-Kyoto(WKY)rats and SHR were divided into four groups;WKY control,SHR control and SHR treated with EGCG(50 mg/kg/day)or losartan(10 mg/kg/day).The treatment was given daily for 4 weeks by oral gavage and the blood pressure was monitored by tail-cuff method every 3 *** endothelium-dependent relaxations were assessed in isolated phenylephrine-precontracted aortic rings at the end of *** vascular levels of reactive oxygen species,nitric oxide,tetrahydrobiopterin,and cyclic guanosine monophosphate were also ***,the expression of angiotensinⅡtype 1(AT_(1))receptor protein was ***:The systolic blood pressure was significantly decreased in SHR treated with *** impaired endothelium-dependent relaxation was significantly improved in aortic ring isolated from the EGCG-treated SHR *** also significantly increased the levels of nitric oxide,tetrahydrobiopterin,and cyclic guanosine monophosphate,while decreasing the level of reactive oxygen species and the protein expression of AT_(1)receptor in ***:EGCG attenuates endothelial dysfunction in SHR by decreasing oxidative stress and increasing vascular nitric oxide bioavailability,which may be modulated partly by inhibition of vascular AT_(1)*** increase in endothelium-dependent relaxation may contribute to a decrease in blood pressure in hypertensive animals.

关键词： Epigallocatechin-3-gallate Vascular protection Antihypertension Tetrahydrobiopterin Cyclic guanosine monophosphate Angiotensin typeⅠreceptor Spontaneously hypertensive rats

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Structural characterization of Nd-doped in silica host matrix prepared by wet chemical process

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Journal of Rare Earths 2009年第1期27卷 83-86页

作者： Surender Duhan Sunita devi m.Singh materials Science Lab Department of Applied Physics Guru Jambheshwar University of Science & Technology materials Science Lab Department of Physics Department of Chemistry Lajpat Rai College Department of Physics Amity School of Engineering and TechnologyAmity University Sec-125

Silica host matrix containing neodymium which is potentially important for the formation of nanocrystalline metal oxides was prepared by solgel method, using tetra-ethoxysilane and Nd（NO3）3 as precursor *** prepared samples were changed from amorphous to nanocrystallites phase at sintered temperature 550 °C（4 h）, 750 °C（8 h） and 950 °C（12 h）.The thermally treated sample microstructures were investigated using X-ray diffraction（XRD）, Fourier transformation infrared spectroscopy（FTIR）, and scanning electron mi-croscopy（SEm）.While a further increase of the temperature at 750 °C and annealing time（8 h） resulted in the formation of cubic and hexagonal Nd2O3 *** constant sintering temperature 950 °C for 12 h, the samples showed sharper and intense *** sizes of Nd2O3 nanocrystallites were characterized by XRD with average size ～46 nm.

关键词： rare earth oxide silica annealing/calcination nanocrystallites

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Student Behavior modeling for an E-Learning System Offering Personalized Learning Experiences

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Computer Systems Science & Engineering 2022年第3期40卷 1127-1144页

作者： K.Abhirami m.K.Kavitha devi Department of Computer Science and Engineering Kings College of EngineeringPudukkottai613303India Department of Computer Science and Engineering Thiagarajar College of EngineeringMadurai625015India

With the advent of computing and communication technologies,it has become possible for a learner to expand his or her knowledge irrespective of the place and ***-based learning promotes active and independent *** scale e-learning platforms revolutionized the concept of studying and it also paved the way for innovative and effective teaching-learning *** digital learning improves the quality of teaching and also promotes educational ***,the challenges in e-learning platforms include dissimilarities in learner’s ability and needs,lack of student motivation towards learning activities and provision for adaptive learning *** quality of learning can be enhanced by analyzing the online learner’s behavioral characteristics and their application of intelligent instructional *** is not possible to identify the difficulties faced during the process through evaluation after the completion of e-learning *** is thus essential for an e-learning system to include component offering adaptive control of learning and maintain user’s interest *** this research work,a framework is proposed to analyze the behavior of online learners and motivate the students towards the learning process accordingly so as to increase the rate of learner’s objective *** to the demands of e-learner,an intelligent model is presented in this study for e-learning system that apply supervised machine learning *** adaptive e-learning system suits every category of learner,improves the learner’s performance and paves way for offering personalized learning experiences.

关键词： Learner behavior modeling e-learning intelligent learning system machine learning algorithm

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A Novel Fuzzy Inference System-Based Endmember Extraction in Hyperspectral Images

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Intelligent Automation & Soft Computing 2023年第8期37卷 2459-2476页

作者： m.R.Vimala devi S.Kalaivani School of Electronics Engineering Vellore Institute of TechnologyVellore632051India

Spectral unmixing helps to identify different components present in the spectral mixtures which occur in the uppermost layer of the area owing to the low spatial resolution of hyperspectral *** spectral unmixing methods are globally based and do not consider the spectral variability among its endmembers that occur due to illumination,atmospheric,and environmental ***,endmember bundle extraction plays a major role in overcoming the above-mentioned limitations leading to more accurate abundance ***,a two-stage approach is proposed to extract endmembers through endmember bundles in hyperspectral *** divide and conquer method is applied as the first step in subset images with only the non-redundant bands to extract endmembers using the Vertex Component Analysis(VCA)and N-FINDR algorithms.A fuzzy rule-based inference system utilizing spectral matching parameters is proposed in the second step to categorize *** endmember with the minimum error is chosen as the final endmember in each specific *** proposed method is simple and automatically considers endmember variability in hyperspectral *** efficiency of the proposed method is evaluated using two real hyperspectral *** average spectral angle and abundance angle are used to analyze the performance measures.

关键词： Hyperspectral image spectral unmixing spectral matching endmember bundles fuzzy inference system

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Blockchain Based Consensus Algorithm and Trustworthy Evaluation of Authenticated Subgraph Queries

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Computer Systems Science & Engineering 2023年第5期45卷 1743-1758页

作者： G.Sharmila m.K.Kavitha devi Department of Computer Science&Engineering Syed Ammal Engineering CollegeRamanathapuram623502India Department of Computer Science&Engineering Thiagarajar College of EngineeringMadurai625015India

Over the past era,subgraph mining from a large collection of graph database is a crucial *** addition,scalability is another big problem due to insufficient *** are several security challenges associated with subgraph mining in today’s on-demand *** address this downside,our proposed work introduces a Blockchain-based Consensus algorithm for Authenticated query search in the Large-Scale Dynamic Graphs(BCCA-LSDG).The two-fold process is handled in the proposed BCCA-LSDG:graph indexing and authenticated query search(query processing).A blockchain-based reputation system is meant to maintain the trust blockchain and cloud server of the proposed *** resolve the issues and provide safe big data transmission,the proposed technique also combines blockchain with a consensus algorithm *** of the big data is ensured by dividing the BC network into distinct networks,each with a restricted number of allowed entities,data kept in the cloud gate server,and data analysis in the *** consensus algorithm is crucial for maintaining the speed,performance and security of the *** Dual Similarity based mapReduce helps in mapping and reducing the relevant subgraphs with the use of optimal feature ***,the graph index refinement process is undertaken to improve the query *** query error,fuzzy logic is used to refine the index of the graph *** proposed technique outperforms advanced methodologies in both blockchain and non-blockchain systems,and the combination of blockchain and subgraph provides a secure communication platform,according to the findings.

关键词： Big data blockchain consensus algorithm trust management graph index

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An application of blended amendments in monsoon rice field

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Ecological Processes 2017年第1期6卷 373-380页

作者： madhumita Ghosh Ashalata devi Department of Environmental Science Tezpur UniversityP.O-784028 NapaamIndia

Introduction:Rice is the main food crop of the world,and the cultivation of rice crop during the monsoon season is hard due to the rain-induced *** from this,farmers in north-eastern regions of India often implement improper crop management leading to poor ***,the development of suitable management practices under improved varieties of rice become essential for increasing rice productivity,improving soil quality status and reducing methane ***:The aim of the study was to investigate the variation in soil properties,crop growth and methane emission under the application of an inorganic fertiliser as well as its mixtures with both inorganic and plant *** such an attempt,a field-based experiment was conducted with the rice variety Chandrama during 2015 in slightly acidic soil having sandy loam *** amendments,*** and NPK,blended separately with magnesium sulphate,fresh neem(Azadirechta indica)leaves,used tea(Camellia sinensis ***)leaves,and fresh karanj(Pongamia glabra)leaves were used for the study with four replications ***:Application of NPK separately with the leaves of neem,tea and karanj separately at the onset of monsoon season markedly affected the soil porosity and the water-holding capacity of the ***,in comparison with sole NPK fertilisation,a significance increase in soil organic matter accumulation(2.48±0.10%)was seen only for karanjblended NPK while magnesium sulphate-blended NPK showed the lowest methane emission(0.30±0.01 mg/m2/h).The rice plants grown on karanj-blended NPK soil showed the highest yield(0.560±0.01 kg/m2)among the five ***:It was found that only the karanj leaves blended NPK could significantly improve the soil organic matter and increase rice yield without intensifying methane emission,while magnesium sulphate blended with NPK could significantly reduce methane emission in the flooded rice paddy soil at 0.5 t/ha application level but

关键词： Inorganic fertiliser Leaves of plants Soil properties Rice yield methane emission

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Intelligent Vehicular Communication Using Vulnerability Scoring Based Routing Protocol

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Intelligent Automation & Soft Computing 2023年第1期35卷 31-45页

作者： m.Ramya devi I.Jasmine Selvakumari Jeya Department of Computer Science and Engineering Hindusthan College of Engineering and TechnologyCoimbatore641050India

Internet of Vehicles(IoV)is an intelligent vehicular technology that allows vehicles to communicate with each other via *** and the Internet of Things(IoT)enable cutting-edge technologies including such self-driving *** the existing systems,there is a maximum communication delay while transmitting the *** proposed system uses hybrid Cooperative,Vehicular Communication management Framework called CAmINO(CA).Further it uses,energy efficient fast message routing protocol with Common Vulnerability Scoring System(CVSS)methodology for improving the communication delay,*** improves security while transmitting the messages through *** this research,we present a unique intelligent vehicular infrastructure communication management *** framework includes additional stability for both short and long-range mobile *** also includes built-in cooperative intelligent transport system(C-ITS)capabilities for experimental verification in real-world *** addition,an energy efficient-fast message distribution routing protocol(EE-FmDRP)has been *** combines the benefits between both temporal and direction oriented routing *** has been suggested for distributing information from the origin ends to the predetermined objective in a quick,accurate,and effective manner in the event of an *** critical value scale score(CVSS)employ ratings to measure the assault probability in markov *** of chained transitions allow us to statistically evaluate the integrity of a group of *** the proposed method helps to enhance the vehicular *** CAmINO with energy efficient fast protocol using CVSS(CA-EEFP-CVSS)method outperforms in terms of shortest transmission latency achieves 2.6 sec,highest throughput 11.6%,and lowest energy usage 17%and PDR 95.78%.

关键词： Intelligent automation intelligent transport system vehicular networks markov chains internet of vehicles critical value scale score

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Efficacy of diurnal BG-Sentinel traps to capture nocturnal adult Armigeres subalbatus mosquitoes and impact of altitudinal variations in forests

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Asian Pacific Journal of Tropical medicine 2019年第11期12卷 512-519页

作者： devi Shankar Suman Zoological Survey of India New AliporeKolkataWest Bengal700053India

Objective:To establish an efficacious and efficient surveillance method of Armigeres(Ar.)subalbatus,a known filarial vector,surviving in forest habitats to estimate realistic population density and assess the impact of altitudinal variations on the efficacy of the ***:In the study,12 locations in areas with an altitudinal range from 82 m to 920 m were selected in three reserve forests for night sampling of adult *** mosquito using standard chemical lure based BG-Sentinel traps and CDC-light traps in *** of locations and time were estimated on the efficacy of traps as mosquito density using multifactor analysis of variance for significant *** of altitudinal variations on the efficacy of traps was assessed using multiple regression with slope ***:BG-Sentinel trap collected significantly more adult ***,4.43 folds in Gorumara NP,5.19 folds in Neora Valley NP and 12.10 folds in mahananda WLS than the CDC-light trap irrespective to ***-Sentinel traps were tolerant of altitudinal variations(80 m-170 m)and showed no significant relationship between density and altitudes in contrast to CDC-light traps which showed a significant negative impact on capturing efficacy with increase in altitudes(Pmore *** mosquitoes during night time in comparison to CDC-light trap under complex climatic conditions of forest and variable altitudes.

关键词： mosquitoes Surveillance Adult mosquito traps Altitudinal variations Armigeres subalbatus

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Structural and optical properties of CZTS nanoparticles prepared by a colloidal process

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Rare metals 2021年第9期40卷 2602-2609页

作者： R.Aruna-devi m.Latha S.Velumani JoséÁlvaro Chávez-Carvayar Program on Nanoscience and Nanotechnology CINVESTAV-IPNSan Pedro Zacatenco07360 Mexico CityMexico CIICAp-UAEm Av.Universidad 1001.Col.Chamilpa62209 CuernavacaMorelosMexico Department of Electrical Engineering(SEES) CINVESTAV-IPNSan Pedro Zacatenco07360 Mexico CityMexico Instituto de Investigaciones en materiales UNAM04510 Mexico CityMexico

This research presents the influence of copper(Cu) concentration on the properties of copper zinc tin sulfide(CZTS) nanoparticles(NPs) synthesized by a colloidal method, employing oleylamine as an organic solvent. From the structural analysis, a pure phase of CZTS was obtained at an optimized molar ratio of 1.8:1.1:1:4,and secondary phases were observed as the Cu concentration increased. The increment of the NPs size from 15 to50 nm was noticed as a function of Cu ***, the optical bandgap energy was tuned from1.35 to 1.68 eV with respect to Cu concentration. The sample synthesized at the molar ratio of 1.8:1.1:1:4 showed a pure phase CZTS with desired elemental composition and bandgap. Furthermore, CZTS thin films were prepared by a doctor-blade method using synthesized NPs followed by annealing under a sulfur/nitrogen atmosphere. The annealed CZTS film showed a significant improvement in the morphological, electrical and optoelectronic ***, the annealed CZTS film can be efficiently used as an absorber layer in low-cost thin film solar cells.

关键词： CZTS Copper concentration Nanoparticles Thin film Annealing

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Novel synthesis and characterization of CuO nanomaterials:Biological applications

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Chinese Chemical Letters 2014年第12期25卷 1615-1619页

作者： Ayekpam Bimolini devi Dinesh Singh moirangthem Narayan Chandra Talukdar m.Damayanti devi N.Rajen Singh meitram Niraj Luwang Department of Chemistry Manipur University Institute of Bioresources and Sustainable Development Department of Biotechnology Department of Life Sciences Manipur University Chemical Engineering and Process Development National Chemical Laboratory

CuO nanoparticles were synthesized at a relatively low temperature（80 ℃） for 2 h using polyethylene glycol-glycerol mixture which acts as a capping agent.A detailed characterization of the synthesized nanomaterials were performed utilizing X-ray diffraction（XRD）,infra-red spectroscopy（IR）,thermogravimetric analysis（TGA-DTA）,transmission electron microscopy（TEm）,photoluminescence（PL） by studying its crystalline phase,vibrational mode,thermal analysis,morphology and photoluminescence *** effect of annealing on the as-prepared nanoparticles were studied and compared with their corresponding bulk *** synthesized nanoparticles have been screened for in vitro cytotoxicity（1C_（50）） studies against the human cervical adenocarcinoma cell line（HeLa） using WITT assay *** as-prepared nanoparticle inhibits the proliferation of this HeLa *** standard disc diffusion method has been used to study the antibacterial activity of the samples against the human pathogenic bacteria Escherichia coli（mTCC 729）,Proteus mirabilis（mTCC 425） and Klebsiella pneumoniae ***（mTCC 432）.The results have been compared with the positive control antibiotic *** synthesized nanoparticles would provide a potential alternative to antibiotics for controlling some of the microorganisms causing urolithiasis.

关键词： CuO nanoparticles Annealing HeLa cell lines Cytotoxicity Antibacterials

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