检索结果-南通市图书馆

Astragali Radix-Notoginseng Radix et Rhizoma medicine pair prevents cardiac remodeling by improving mitochondrial dynamic balance

引用

Chinese Journal of Natural Medicines 2025年第1期23卷 54-63页

作者： Pingping lin Hong Chen Zekun Cui Boyang Yu Junping Kou Fang Li Jiangsu Key Laboratory of TCM Evaluation and Translational Research Research Center for Traceability and Standardization of TCMs School of Traditional Chinese PharmacyChina Pharmaceutical University

Astragali Radix(AR) and Notoginseng Radix et Rhizoma(NR) are frequently employed in cardiovascular disease treatment. However, the efficacy of the AR-NR medicine pair(AN) in improving cardiac remodeling and its underlying mechanism remains unclear. This study aimed to evaluate AN's cardioprotective effect and potential mechanism on cardiac remodeling using transverse aortic constriction(TAC) in mice and angiotensin II(Ang II)-induced neonatal rat cardiomyocytes(NRCMs) and fibroblasts in vitro. High-performance liquid chromatography-quadrupole-time of flight tandem mass spectrometry(HPLC-Q-TOF-MS/MS) characterized 23 main components of AN. AN significantly improved cardiac function in the TAC-induced mice. Furthermore, AN considerably reduced the serum levels of N-terminal pro-B-type natriuretic peptide(NT-pro BNP), cardiac troponin T(CTn-T), and interleukin-6(IL-6) and mitigated inflammatory cell infiltration. Post-AN treatment, TAC-induced heart size approached normal. AN decreased cardiomyocyte cross-sectional area and attenuated the upregulation of cardiac hypertrophy marker genes(ANP, BNP, and MYH7) in vivo and in ***, AN alleviated collagen deposition in TAC-induced mice. AN also reduced the expression of fibrosis-related indicators(COL1A1 and COL3A1) and inhibited the activation of the transforming growth factor-β1(TGF-β1)/mothers against decapentaplegic homolog 3(Smad3) pathway. Thus, AN improved TAC-induced cardiac remodeling. Moreover, AN downregulated p-dynamin-related protein(Drp1)(Ser616) expression and upregulated mitogen 2(MFN-2) and optic atrophy 1(OPA1) expression in vivo and in vitro, thereby restoring mitochondrial fusion and fission balance. In conclusion, AN improves cardiac remodeling by regulating mitochondrial dynamic balance, providing experimental data for the rational application of Chinese medicine prescriptions with AN as the main component in clinical practice.

关键词： Astragali Radix−Notoginseng Radix et Rhizoma medicine pair Cardiac fibrosis Cardiac hypertrophy Mitochondrial dynamics Transforming growth factor-β1/Smad3 pathway

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Ru/NiMnB spherical cluster pillar for highly proficient green hydrogen electrocatalyst at high current density

引用

Journal of Energy Chemistry 2025年第1期100卷 397-408页

作者： Md Ahasan Habib Shusen lin Mehedi Hasan Joni Sumiya Akter Dristy Rutuja Mandavkar Jae-Hun Jeong Jihoon Lee Department of Electronic Engineering College of Electronics and InformationKwangwoon UniversityNowon-guSeoul 01897Republic of Korea

Advanced OER/HER electrocatalytic alternatives are crucial for the wide adaptation of green hydrogen ***,Ru/NiMnB spherical cluster pillar(SCP),denoted as Ru/NiMnB,is synthesized using a combination of electro-deposition and hydrothermal *** investigation of Ru doping in the NiMnB matrix revealed significant improvements in electrocatalytic *** Ru/NiMnB SCPs demonstrate superior OER/HER activity with low overpotentials of 150 and 103 mV at 50mA/cm^(2)in 1 M KOH,making them highly competitive with state-of-the-art ***,the Ru/NiMnB SCPs exhibit a low 2-E cell voltage of 2.80 V at ultra-high current density of 2,000 m A/cm^(2)in 1 M KOH,outperforming the standard benchmark electrodes of RuO_(2)||Pt/C,thereby positioning Ru/NiMnB as one of the best bifunctional *** SCPs exhibit exceptional high-current characteristics,stability and corrosion resistance,as evidenced by continuous operation at 1,000 mA/cm^(2)high-current density for over 150 h in 6 M KOH at elevated temperatures under harsh industrial *** a small amount of Ru incorporation significantly enhances the electrocatalytic performances of NiMnB,attributed to increased active sites and improved intrinsic properties such as conductivity,adsorption/desorption capability and reaction ***,Ru/NiMnB SCPs present a promising bi-functional electrode concept for efficient green H_(2)production.

关键词： Advanced electrocatalyst High current Corrosion resistance Industrial requirement

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Development and application of an intelligent thermal state monitoring system for sintering machine tails based on CNN-LSTM hybrid neural networks

引用

Journal of Iron and Steel Research International 2025年第1期32卷 52-63页

作者： Da-lin Xiong Xin-yu Zhang Zheng-wei Yu Xue-feng Zhang Hong-ming Long Liang-jun Chen Anhui Province Key Laboratory of Metallurgical Engineering&Resources Recycling Anhui University of TechnologyMa’anshan243002AnhuiChina School of Metallurgical Engineering Anhui University of TechnologyMa’anshan243032AnhuiChina School of Computer Science Anhui University of TechnologyMa’anshan243032AnhuiChina

Real-time prediction and precise control of sinter quality are pivotal for energy saving,cost reduction,quality improvement and efficiency enhancement in the ironmaking *** advance,the accuracy and comprehensiveness of sinter quality prediction,an intelligent flare monitoring system for sintering machine tails that combines hybrid neural networks integrating convolutional neural network with long short-term memory(CNN-LSTM)networks was *** system utilized a high-temperature thermal imager for image acquisition at the sintering machine tail and employed a zone-triggered method to accurately capture dynamic feature images under challenging conditions of high-temperature,high dust,and *** feature images were then segmented through a triple-iteration multi-thresholding approach based on the maximum between-class variance method to minimize detail loss during the segmentation *** the advantages of CNN and LSTM networks in capturing temporal and spatial information,a comprehensive model for sinter quality prediction was constructed,with inputs including the proportion of combustion layer,porosity rate,temperature distribution,and image features obtained from the convolutional neural network,and outputs comprising quality indicators such as underburning index,uniformity index,and FeO content of the *** accuracy is notably increased,achieving a 95.8%hit rate within an error margin of±*** the system is applied,the average qualified rate of FeO content increases from 87.24%to 89.99%,representing an improvement of 2.75%.The average monthly solid fuel consumption is reduced from 49.75 to 46.44 kg/t,leading to a 6.65%reduction and underscoring significant energy saving and cost reduction effects.

关键词： Sinter quality Convolutional neural network Long short-term memory Image segmentation FeO prediction

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Combination therapy strategy based on selective internal radiation therapy as conversion therapy for inoperable giant hepatocellular carcinoma:A case report

引用

World Journal of Gastrointestinal Oncology 2025年第3期17卷 410-417页

作者： Ming-Zhi Hao Hai-Lan lin Yu-Bin Hu Qi-Zhong Chen Zhang-Xian Chen lin-Bin Qiu Duan-Yu lin Hui Zhang De-Chun Zheng Zhu-Ting Fang Jing-Feng Liu Department of Tumor Interventional Radiology Clinical Ocology School of Fujian Medical UniversityFujian Cancer HospitalFuzhou 350014Fujian ProvinceChina Department of Oncology and Vascular Interventional Radiology Clinical Oncology School of Fujian Medical UniversityFuzhou 350014Fujian ProvinceChina Department of Nuclear Medicine Clinical Oncology School of Fujian Medical UniversityFuzhou 350014Fujian ProvinceChina Department of Hepatopancreatobiliary Surgical Oncology Clinical Oncology School of Fujian Medical UniversityFujian Cancer HospitalFuzhou 350014Fujian ProvinceChina Department of Radiology Clinical Oncology School of Fujian Medical UniversityFujian Cancer HospitalFuzhou 350014Fujian ProvinceChina Department of Oncology and Vascular Interventional Radiology Clinical Oncology School of Fujian Medical UniversityFujian Cancer HospitalFuzhou 350014Fujian ProvinceChina Department of Hepatobiliary Surgery Clinical Oncology School of Fujian Medical UniversityFujian Cancer HospitalFuzhou 350014Fujian ProvinceChina

BACKGROUND Hepatocellular carcinoma(HCC)has become a growing health concern *** invasion and high tumor burden are key factors limiting the curative effect of selective internal radiation therapy(SIRT).CASE SUMMARY This case study reports a 49-year-old woman who was diagnosed with China Liver Cancer Staging(CNLC)IIIa HCC and>15 cm tumor ***,due to insufficient future liver remnant and vascular invasion,the tumor was unresectable;however,radical hepatectomy was performed after successful conversion therapy with SIRT using yttrium-90(90Y)resin microspheres followed by hepatic arterial infusion chemotherapy(HAIC)with tyrosine kinase inhibitor(TKI)and anti-programmed death-1(PD-1)*** using 90Y resin microspheres was given by the right hepatic artery and chemoembolization was simultaneously performed in the tumor’s feeding vessels from the right diaphragmatic *** was followed every three weeks with lenvatinib and *** 4 months post-SIRT,the tumor was downstaged to CNLC Ib and the patient successfully underwent *** histopathological examination of the resected specimen showed extensive *** This case study provides evidence for an integrated treatment strategy combining SIRT and HAIC with TKI and anti-PD-1 antibodies for patients with large HCC and microvascular *** confirmatory trials are required in the future.

关键词： Selective internal radiation therapy Hepatic arterial infusion chemotherapy Yttrium-90 resin microspheres Hepatocellular carcinoma Conversion therapy Case report

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Pilot-scale testing on catalytic hydrolysis of carbonyl sulfur combined with absorption-oxidation of H_(2)S for blast furnace gas purification

引用

Journal of Environmental Sciences 2025年第5期151卷 360-372页

作者： Yuting lin Yuran Li Bin Wang Jinglei Tian Hongqiang Liu Yiren Li Zhicheng Xu Qiang Cao Tingyu Zhu CAS Key Laboratory of Green Process and Engineering Institute of Process EngineeringInnovation Academy for Green ManufactureChinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100190China HBIS Group Co. Ltd.Shijiazhuang 050023China Center for Excellence in Regional Atmospheric Environment Institute of Urban EnvironmentChinese Academy of SciencesXiamen 361021China

About 70%of the flue gas in the iron-steel industry has achieved multi-pollutant ultra-low emissions in China until 2023,and then the blast furnace gas purification has become the control step and *** research group has designed and constructed the world’s first blast furnace gas desulfurization pilot plant with the scale of 2000 Nm^(3)/h in October *** pilot plant is a two-step combined desulfurization device including catalytic hydrolysis of carbonyl sulfur(COS)and absorption-oxidation of H_(2)S,continuously running for 120 *** the hydrolysis system,one reason for catalyst deactivation has been verified from the sulfur *** in blast furnace gas can be hydrolyzed on the hydrolysis catalyst to produce the nitrogen deposition,which is one of the reasons for catalyst deactivation and has never been found in previous *** deposition forms of S and N elements are determined,S element forms elemental sulfur and sulfate,while N element forms-NH_(2)and NH_(4)^(+).In the absorption-oxidation system,the O_(2)loading and the residence time have been optimized to control the oxidation of HS^(−)to produce elemental sulfur instead of by-product S_(2)O_(3)^(2−).The balance and distribution of S and N elements have been calculated for thewholemulti-phase system,approximately 84.4%of the sulfur is converted to solid sulfur product,about 1.3%of the sulfur and 19.2%of N element are deposited on the hydrolysis *** pilot plant provides technical support formulti-pollutant control of blast furnace.

关键词： Blast furnace gas Carbonyl sulfur Hydrogen sulfide Hydrogen cyanide Hydrolysis and oxidation Activated carbon

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Optimizing Stand-Alone PV Systems:A Metaheuristic-Enhanced Fuzzy Approach for Adaptive MPPT

引用

China Communications 2025年第1期22卷 61-74页

作者： Tina Samavat Mostafa Nazari lin Fuhong Lei Yang Department of Computer Science and Engineering University of NevadaRenoNVUSA Faculty of Mechanical Engineering Shahrood University of TechnologyShahroodIran School of Computer and Communication Engineering University of Science and Technology BeijingBeijing 100083China

This paper introduces a simple yet effective approach for developing fuzzy logic controllers(FLCs)to identify the maximum power point(MPP)and optimize the photovoltaic(PV)system to extract the maximum power in different environmental *** propose a robust FLC with low computational complexity by reducing the number of membership functions and *** optimize the performance of the FLC,metaheuristic algorithms are employed to determine the parameters of the *** evaluate the proposed FLC in various panel configurations under different environmental *** results indicate that the proposed FLC can easily adapt to various panel configurations and perform better than other benchmarks in terms of enhanced stability,responsiveness,and power transfer under various scenarios.

关键词： genetic algorithm imperialist competitive algorithm invasive weed algorithm maximum power point tracking

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

An association analysis of lipidome and transcriptome highlights the involvement of MmGDPD1 in regulating low phosphorus tolerance in Malus mandshurica

引用

Horticultural Plant Journal 2025年第1期11卷 85-104页

作者： Hong Zhao Yawei Wu Luonan Shen Zhengchun Li lin Deng Xiaopeng Wen Key Laboratory of Plant Resource Conservation and Germplasm Innovation in Mountainous Region(Ministry of Education) Institute of Agro-bioengineering/College of Life SciencesGuizhou UniversityGuiyangGuizhou 550025China Institute of Pomology Science Guizhou Academy of Agricultural SciencesGuiyangGuizhou 550006China College of Forestry/Institute for Forest Resources&Environment of Guizhou Guizhou UniversityGuiyangGuizhou 550025China

Phosphorus(Pi)plays a crucial role in the growth and development of *** lipid regulation is one of the main mechanisms underlying plant adaptation to Pi ***,the high tolerance to low-Pi stress was justified in an elite line,MSDZ 109,which was obtained from Malus *** better understand the mechanism underlying high adaptation to low-Pi stress,currently,lipidomic and transcriptomic analysis,as well as CRISPR/Cas9 and MmGDPD1-overexpressing methodologies were comprehensively integrated into a strategy for elucidating the high tolerance to low-Pi ***,770 differential metabolites were identified from the roots between the low-Pi and stress-free,belonging to 21 sub-classes of lipid *** acids(FA)constituted the predominant lipid component,accounting for approximately 50%-60%of the total lipids,and triglycerides(TAG)ranked the second,comprising around 12%of the total,consecutively followed by phosphatidylcholine(PC)and diacylglycerol(DAG)with approximately 10%and 8%of the total,*** synchronous transcriptomic analysis revealed a significant up-regulation of genes related to glycerophospholipid and glycerolipid metabolism,specifically those(e.g.,MmGDPD1,MmDGDG1,MmMGDG1,MmSQDG,etc.)involved in phospholipid and galactosyl synthesis in response to low-Pi *** fusing reporter assay showed that MmGDPD1 promoter induced GUS gene expression and demonstrated initiation *** on expression analysis,a dual-luciferase reporter assay,as well as yeast one-hybrid(Y1H)identification,MmPHR1 was justified to bind with the MmGDPD1 promoter and positively regulate plant tolerance to low-Pi *** further elucidate the role of MmGDPD1,CRISPR/Cas9 and MmGDPD1-overexpressing vectors were successfully introduced into apple(‘Royal Gala')***,the MmGDPD1-KO line calli exhibited the remarkable decreases in the contents of phosphodiesterase(PDE),activity,as well as the contents of total Pi,and P

关键词： Malus mandshurica Lipidome profiling Transcription profiles Low phosphorus stress MmGDPD1

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Low Complexity Successive Cancellation List Decoding of U-UV Codes

引用

China Communications 2025年第1期22卷 41-60页

作者： Chen Wenhao Chen Li lin Jingyu Zhang Huazi School of Electronics and Information Technology Sun Yat-sen UniversityGuangzhou 510006China Guangdong Province Key Laboratory of Information Security Technology Guangzhou 510006China Hangzhou Research Center Huawei Technologies Co.Ltd.Hangzhou 310052China

Constituted by BCH component codes and its ordered statistics decoding(OSD),the successive cancellation list(SCL)decoding of U-UV structural codes can provide competent error-correction performance in the short-to-medium length ***,this list decoding complexity becomes formidable as the decoding output list size *** is primarily incurred by the *** this challenge,this paper proposes the low complexity SCL decoding through reducing the complexity of component code decoding,and pruning the redundant SCL decoding *** the former,an efficient skipping rule is introduced for the OSD so that the higher order decoding can be skipped when they are not possible to provide a more likely codeword *** is further extended to the OSD variant,the box-andmatch algorithm(BMA),in facilitating the component code ***,through estimating the correlation distance lower bounds(CDLBs)of the component code decoding outputs,a path pruning(PP)-SCL decoding is proposed to further facilitate the decoding of U-UV *** particular,its integration with the improved OSD and BMA is *** results show that significant complexity reduction can be ***,the U-UV codes can outperform the cyclic redundancy check(CRC)-polar codes with a similar decoding complexity.

关键词： ordered statistics decoding successive cancellation list decoding U-UV codes

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

ET-Net:A Novel Framework for Fine-Grained Traffic Classification in Intelligent Vehicle Applications

引用

China Communications 2025年第1期22卷 265-276页

作者： Wei Wenjie Ji Nan Gao Feiran lin Fuhong School of Computer and Communication Engineering University of Science and Technology BeijingBeijing 100083China China Communications Magazine Co.LTD Beijing 100081China Beijing-Dublin International College Beijing University of TechnologyBeijing 100124China North China Electric Power University Beijing 102206China

Intelligent vehicle applications provide convenience but raise privacy and security *** of sensitive data,including vehicle location,and facial recognition information,poses a threat to user ***,traffic classification is vital for promptly overseeing and controlling applications with sensitive *** this paper,we propose ETNet,a framework that combines multiple features and leverages self-attention mechanisms to learn deep relationships between ***-Net employs a multisimilarity triplet network to extract features from raw bytes,and exploits self-attention to capture long-range dependencies within packets in a session and contextual information ***,we utilizing the loss function to more effectively integrate information acquired from both byte sequences and their corresponding *** simulated evaluations on datasets with similar attributes,ET-Net demonstrates the ability to finely distinguish between nine categories of applications,achieving superior results compared to existing methods.

关键词： attention mechanism encrypted traffic classification intelligent vehicles privacy and security

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Design of multifunctional interfaces on ceramic solid electrolytes for high-performance lithium-air batteries

引用

Green Energy & Environment 2025年第1期10卷 183-192页

作者： Yunxin Shi Ziyang Guo Changhong Wang Mingze Gao Xiaoting lin Hui Duan Yonggang Wang Xueliang Sun College of Energy Material and Chemistry College of Chemistry and Chemical EngineeringInner Mongolia UniversityHohhot010021China Department of Mechanical and Materials Engineering Western UniversityLondonONN6A 5B9Canada Department of Chemistry and Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials Institute of New EnergyiChEM(Collaborative Innovation Center of Chemistry for Energy Materials)Fudan UniversityShanghai200433China Eastern Institute for Advanced Study Eastern Institute of TechnologyNingboZhejiang315100China

High-energy-density lithium(Li)–air cells have been considered a promising energy-storage system,but the liquid electrolyte-related safety and side-reaction problems seriously hinder their *** address these above issues,solid-state Li–air batteries have been widely ***,many commonly-used solid electrolytes generally face huge interface impedance inLi–air cells and also showpoor stability towards ambient air/Li ***,we fabricate a differentiating surface-regulated ceramic-based composite electrolyte(DSCCE)by constructing disparately LiI-containing polymethyl methacrylate(PMMA)coating and Poly(vinylidene fluoride-co-hexafluoropropylene)(PVDF-HFP)layer on both sides of Li_(1.5)Al_(0.5)Ge_(1.5)(PO_(4))_(3)(LAGP).The cathode-friendly LiI/PMMA layer displays excellent stability towards superoxide intermediates and also greatly reduces the decomposition voltage of discharge products in Li–air ***,the anode-friendly PVDF-HFP coating shows low-resistance properties towards ***,Li dendrite/passivation derived from liquid electrolyte-induced side reactions and air/I-attacking can be obviously suppressed by the uniformand compact composite *** a result,the DSCCE-based Li–air batteries possess high capacity/low voltage polarization(11,836mAh g^(-1)/1.45Vunder 500mAg^(-1)),good rate performance(capacity ratio under 1000mAg^(-1)/250mAg^(-1) is 68.2%)and longterm stable cell operation(~300 cycles at 750 mA g^(-1) with 750 mAh g^(-1))in ambient air.

关键词： Li-air batteries Li_(1.5)Al_(0.5)Ge_(1.5)(PO_(4))_(3) Polymers Composite electrolyte Ambient air

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：