检索结果-南通市图书馆

Frontiers of Structural and Civil Engineering 2024年第5期18卷 788-804页

作者： dexiang li Jingyu Huang College of Civil Engineering Tongji UniversityShanghai 200092China National Maglev Transportation Engineering R&D Center Tongji UniversityShanghai 201804China

The high-speed maglev vehicle/guideway coupled model is an essential simulation tool for investigating vehicle dynamics and mitigating coupled *** improve its accuracy efficiently,this study investigated a hierarchical model updating method integrated with field ***,a high-speed maglev vehicle/guideway coupled model,taking into account the real effect of guideway material properties and elastic restraint of bearings,was developed by integrating the finite element method,multi-body dynamics,and electromagnetic levitation ***,simultaneous in-site measurements of the vehicle/guideway were conducted on a high-speed maglev test line to analyze the system response and structural modal *** the hierarchical updating,an Elman neural network with the optimal Latin hypercube sampling method was used to substitute the FE guideway model,thus improving the computational *** multi-objective particle swarm optimization algorithm with the gray relational projection method was applied to hierarchically update the parameters of the guideway layer and magnetic force layer based on the measured modal parameters and the electromagnet vibration,***,the updated coupled model was compared with the field measurements,and the results demonstrated the model’s accuracy in simulating the actual dynamic response,validating the effectiveness of the updating method.

关键词： high-speed maglev vehicle/guideway coupled model field measurement model updating neural network multi-objective optimization

Hyperbaric oxygen therapy for cerebral blood flow and electroencephalogram in patients with acute cerebral infarction Choice for therapeutic occasion

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2007年第3期2卷 171-174页

作者： Lei Chen Fei li dexiang Gu Department of Neurology Shidong Hospital Yangpu District Shanghai 200438 China

BACKGROUND： Hyperbaric oxygen （HBO） therapy increases blood oxygen content, changes cerebral blood flow （CBF） and cerebral metabolism. Its therapeutic effects on cerebrovascular disease have been fully confirmed, but the occasion for HBO therapy is still unclear. OBJECTIVE： To observe the therapeutic effects of HBO therapy at different time on CBF and electroencephalogram （EEG） in patients with acute cerebral infarction （CI）. DESIGN： Randomized controlled trial. SETTING： Department of Neurology, Shidong Hospital, Yangpu District of Shanghai. PARTICIPANTS： Ninety-six inpatients with acute CI, admitted to Department of Neurology, Shidong Hospital, Yangpu District of Shanghai from January 2001 to December 2006, were involved in this experiment. The involved participants met the diagnosis criteria of acute CI and confirmed by skull CT or MRI. They all were patients with moderate CI （16- 30 points） according to neurologic deficit score formulated by Chinese Medical Association. Informed consents of detected items and therapeutic regimen were obtained from all the involved participants. They were randomized into two groups with 48 in each： early-stage treatment group and advanced-stage treatment group. Among the 48 patients in the early-stage treatment group, 21 male and 27 female, aged 53 -68 years, 22 patients were found with basal ganglia infarction, 10 with brain lobe infarction, 16 with multiple infarction, 27 accompanied with hypertension and 2 accompanied with diabetes meUitus. Among the 48 patients in the advanced-stage treatment group, 23 male and 25 female, aged 52 - 71 years, 25 patients were found with basal ganglia infarction, 10 with brain lobe infarction, 12 with multiple infarction, 1 with brain stem infarction, 28 accompanied with hypertension and 1 accompanied with diabetes mellitus. METHODS： After admission, patients of two groups received routine drug treatment. ① Patients in the early-stage treatment group and advanced-stage treatment group began to r

关键词： rehabilitation cerebra/infarction cerebral blood flow electroencephalography

CO2 geological storage into a lateral aquifer of an offshore gas field in the South China Sea： storage safety and project design

在线全文

学校读者我要写书评

暂无评论

Frontiers of Earth Science 2015年第2期9卷 286-299页

作者： liang ZHANG dexiang li Justin EZEKIEL Weidong ZHANG Honggang MI Shaoran REN School of Petroleum Engineering China University of Petroleum (Huadong) Qingdao 266580 China Zhanjiang Branch Company of China National Offshore Oil Corporation Zhanjiang 524000 China

The DFI-1 gas South China Sea, contains thus there is great concern field, located in the western a high concentration of CO2, about the need to reduce the CO2 emissions. Many options have been considered in recent years to dispose of the CO2 separated from the natural gas stream on the Hainan Island. In this study, the feasibility of CO2 storage in the lateral saline aquifer of the DF 1-1 gas field is assessed, including aquifer selection and geological assessment, CO2 migration and storage safety, project design, and economic analysis. Six offshore aquifers have been investigated for CO2 geological storage. The lateral aquifer of the DFI-1 gas field has been selected as the best target for CO2 injection and storage because of its proven sealing ability, and the large storage capacity of the combined aquifer and hydrocarbon reservoir geological structure. The separated CO2 will be dehydrated on the Hainan Island and transported by a long- distance subsea pipeline in supercritical or liquid state to the central platform of the DFI-1 gas field for pressure adjustment. The CO2 will then be injected into the lateral aquifer via a subsea well-head through a horizontal well. Reservoir simulations suggest that the injected CO2 will migrate slowly upwards in the aquifer without disturbing the natural gas production. The scoping economic analysis shows that the unit storage cost of the project is approximately US$26-31/ton CO2 with the subsea pipe- line as the main contributor to capital expenditure （CAPEX）, and the dehydration system as the main factor of operating expenditure （OPEX）.

关键词： DFI-1 gas field C02 storage lateral salineaquifer storage safety project design

PHYSICO-CHEMICAL PROPERTIES OF NaF-AIF_3-BaCl_2-NaCl ELECTROLYTE SYSTEM

在线全文

学校读者我要写书评

暂无评论

中国有色金属学会会刊：英文版 1994年第1期4卷 45-49页

作者： li,Guohua li ,dexiang(Department of Nom-ferrous Metallurgy, Nortbeaxrrn Unuersity, Shenyang 110006 , China)

ＰＨＹＳＩＣＯ－ＣＨＥＭＩＣＡＬＰＲＯＰＥＲＴＩＥＳＯＦＮａＦ－ＡＩＦ３－ＢａＣ１２－ＮａＣＩＥＬＥＣＴＲＯＬＹＴＥＳＹＳＴＥＭＬｉ，Ｇｕｏｈｕａ；Ｌｉ，Ｄｅｘｉａｎｇ（ＤｅｐａｒｔｍｅｎｔｏｆＮｏｍ－ｆｅｒｒｏｕｓ... 详细信息

ＰＨＹＳＩＣＯ－ＣＨＥＭＩＣＡＬＰＲＯＰＥＲＴＩＥＳＯＦＮａＦ－ＡＩＦ３－ＢａＣ１２－ＮａＣＩＥＬＥＣＴＲＯＬＹＴＥＳＹＳＴＥＭＬｉ，Ｇｕｏｈｕａ；Ｌｉ，Ｄｅｘｉａｎｇ（ＤｅｐａｒｔｍｅｎｔｏｆＮｏｍ－ｆｅｒｒｏｕｓＭｅｔａｌｌｕｒｇｙ，Ｎｏｒｔｂｅ...

关键词： : Aluminium refining electrolyte energy-saving

Hydrogen sulfide reduces oxidative stress in Huntington's disease via Nrf2

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第6期20卷 1776-1788页

作者： Zige Jiang dexiang liu Tingting li Chengcheng Gai Danqing Xin Yijing Zhao Yan Song Yahong Cheng Tong li Zhen Wang Department of Physiology School of Basic Medical SciencesCheeloo College of MedicineShandong UniversityJinanShandong ProvinceChina Department of Medical Psychology and Ethics School of Basic Medicine SciencesCheeloo College of MedicineShandong UniversityJinanShandong ProvinceChina Department of Neurosurgery Surgery Qingdao Municipal HospitalQingdaoShandong ProvinceChina

The pathophysiology of Huntington's disease involves high levels of the neurotoxin quinolinic acid. Quinolinic acid accumulation results in oxidative stress, which leads to neurotoxicity. However, the molecular and cellular mechanisms by which quinolinic acid contributes to Huntington's disease pathology remain unknown. In this study, we established in vitro and in vivo models of Huntington's disease by administering quinolinic acid to the PC12 neuronal cell line and the striatum of mice, respectively. We observed a decrease in the levels of hydrogen sulfide in both PC12 cells and mouse serum, which was accompanied by down-regulation of cystathionine β-synthase, an enzyme responsible for hydrogen sulfide production. However, treatment with NaHS(a hydrogen sulfide donor) increased hydrogen sulfide levels in the neurons and in mouse serum, as well as cystathionine β-synthase expression in the neurons and the mouse striatum, while also improving oxidative imbalance and mitochondrial dysfunction in PC12 cells and the mouse striatum. These beneficial effects correlated with upregulation of nuclear factor erythroid 2-related factor 2 expression. Finally, treatment with the nuclear factor erythroid 2-related factor 2inhibitor ML385 reversed the beneficial impact of exogenous hydrogen sulfide on quinolinic acid-induced oxidative stress. Taken together, our findings show that hydrogen sulfide reduces oxidative stress in Huntington's disease by activating nuclear factor erythroid 2-related factor 2,suggesting that hydrogen sulfide is a novel neuroprotective drug candidate for treating patients with Huntington's disease.

关键词： apoptosis cystathionine-β-synthase nuclear factor erythroid 2-related factor 2 Huntington's disease hydrogen sulfide mitochondrion neuroplasticity oxidative stress quinolinic acid reactive oxygen species

在线全文

学校读者我要写书评

暂无评论

应用生态位理论分析建筑现象

世界建筑 2007年第4期 132-134页

作者：栗德祥清华大学建筑学院

生态位理论是生态学中的一个重要理论,目前已被引入多个学科领域,生态位理论应用于建筑领域,可以从新的视角诠释各种城市与建筑现象,指导生态环境建设。本文应用生态位理论分析了若干城市与建筑实例。

关键词：生态位适宜性生态位重叠生态位分离

在线全文

学校读者我要写书评

暂无评论

工业废弃地土地更新利用的框架、模式与程序

城市规划学刊 2009年第3期 69-74页

作者：刘抚英栗德祥浙江工业大学生态城市与绿色建筑研究所浙江工业大学建工学院建筑系清华大学建筑学院

工业废弃地系统由环境子系统、经济子系统和社会子系统构成。基于对各子系统进化主导因素的分析选择,提出工业废弃地土地更新利用的框架分别为环境子系统的生态系统进化、经济子系统的产业结构优化、社会子系统的社会利益维系以及系统... 详细信息

工业废弃地系统由环境子系统、经济子系统和社会子系统构成。基于对各子系统进化主导因素的分析选择,提出工业废弃地土地更新利用的框架分别为环境子系统的生态系统进化、经济子系统的产业结构优化、社会子系统的社会利益维系以及系统整体的发展循环经济,论述了4个框架下土地更新利用的11种模式,提出了工业废弃地土地更新利用的程序。

关键词：工业废弃地生态系统产业结构社会利益循环经济

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

当前城市设计实践与研究中的若干问题

建筑学报 2007年第3期 14-17页

作者：李亮栗德祥清华大学建筑学院北京100084

当前城市设计实践和研究中存在着诸如:理念问题——对城市设计中生态价值和人文意义的忽视;价值问题——城市设计对众多社会问题缺乏应对措施;实施问题——很多城市设计缺乏可操作性;定位问题——城市设计和城市规划的关系界定模糊;制... 详细信息

当前城市设计实践和研究中存在着诸如:理念问题——对城市设计中生态价值和人文意义的忽视;价值问题——城市设计对众多社会问题缺乏应对措施;实施问题——很多城市设计缺乏可操作性;定位问题——城市设计和城市规划的关系界定模糊;制度问题——对城市设计需要什么样的制度保障存在争议等。论文针对这些问题提出了相应解决方法。

关键词：城市设计问题解决方法

建筑学的千年涅槃——建筑的学科困境与自我拯救

在线全文

学校读者我要写书评

暂无评论

建筑学报 2001年第4期 4-6页

作者：栗德祥周榕清华大学建筑学院

当代建筑学和建筑创作的根本困境是问题枯竭和问题域困境 ,解决此困境的根本之道在于通过学科重点问题域跃迁而产生的建筑学范式革命 ,现代建筑学内部已经无法提供这一革命的原动力 ,必须依靠学科交叉的方法 ,来形成未来建筑学的动态问... 详细信息

当代建筑学和建筑创作的根本困境是问题枯竭和问题域困境 ,解决此困境的根本之道在于通过学科重点问题域跃迁而产生的建筑学范式革命 ,现代建筑学内部已经无法提供这一革命的原动力 ,必须依靠学科交叉的方法 ,来形成未来建筑学的动态问题域。

关键词：建筑学建筑创作

在线全文

学校读者我要写书评

暂无评论

织造

世界建筑 2005年第8期 89-93页

作者：田野栗德祥清华大学建筑学院

本文从以多位建筑师作品的案例分析为起点,追溯建筑的织造原型。阐述编织技术对原始人类建筑建造方式的影响,从而解释织造概念的意义,并指出织造带给建筑的技术和文化方面的双重涵义。

关键词：编织建造文化