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Curcumin reverses T cell-mediated adaptive immune dysfunctions in tumor-bearing hosts

Cellular & Molecular Immunology 2010年第4期7卷 306-315页

作者： Sankar Bhattacharyya dewan md sakib hossain Suchismita Mohanty Gouri Sankar Sen Sreya Chattopadhyay Shuvomoy Banerjee Juni Chakraborty Kaushik Das Diptendra Sarkar Tanya Das Gaurisankar Sa Division of Molecular Medicine Bose InstituteKolkataIndia

Immune dysfunction is well documented during tumor progression and likely contributes to tumor immune ***81 cytotoxic T lymphocytes(CTLs)are involved in antigen-specific tumor destruction and CD41 T cells are essential for helping this CD81 T cell-dependent tumor *** often target and inhibit T-cell function to escape from immune *** dysfunction includes loss of effector and memory T cells,bias towards type 2 cytokines and expansion of T regulatory(Treg)*** has previously been shown to have antitumor activity and some research has addressed the immunoprotective potential of this plant-derived polyphenol in tumor-bearing *** we examined the role of curcumin in the prevention of tumor-induced dysfunction of T cell-based immune *** observed severe loss of both effector and memory T-cell populations,downregulation of type 1 and upregulation of type 2 immune responses and decreased proliferation of effector T cells in the presence of ***,in turn,prevented this loss of T cells,expanded central memory T cell(TCM)/effector memory T cell(TEM)populations,reversed the type 2 immune bias and attenuated the tumor-induced inhibition of T-cell proliferation in tumor-bearing *** investigation revealed that tumor burden upregulated Treg cell populations and stimulated the production of the immunosuppressive cytokines transforming growth factor(TGF)-b and IL-10 in these ***,however,inhibited the suppressive activity of Treg cells by downregulating the production of TGF-b and IL-10 in these *** importantly,curcumin treatment enhanced the ability of effector T cells to kill cancer ***,our observations suggest that the unique properties of curcumin may be exploited for successful attenuation of tumor-induced suppression of cell-mediated immune responses.

关键词： CD41/CD81 T cell Effector T cell T-regulatory cell FoxP3 Th1/Th2

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Investigation of phase-change materials for interior temperature regulation in public transport

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Clean Energy 2022年第1期6卷 178-192页

作者： md Nahidul Islam md Nahid hossain dewan HasanAhmed Department of Mechanical and Production Engineering Ahsanullah University of Science and Technology141-142 Love RoadTejgaon Industrial AreaDhakaBangladesh

Regulating the indoor temperature of public transport on hot sunny days is a prime concern,as both the external and internal heat sources play an active role in heat *** studies have been carried out on a bus model using sodium sulphate decahydrate as a phase-change material(PCM)that is placed in between the ceiling and the *** are conducted on a sunny day and also for different cases of external(300-W surface heater)and internal(25-W light bulb)heat *** results show that PCM,in the presence of an external heat source,can help to keep the indoor temperature lower and delay the time period for increasing the temperature by absorbing heat during the phase *** the other hand,the presence of the internal heat source contributes to a detrimental effect on the indoor temperature,which gradually increases with the elapse of *** the combination of the external and internal heat sources,it is found that the internal heat source plays a dominating factor to raise the indoor *** is revealed from the experimental results that a 12.7-mm single layer and a single PCM are not enough to counter the internal heat of 25 W unless the thickness of the PCM layer is increased to delay the increase in the indoor *** additional PCM layer with a lower melting temperature could be placed at the inner portion of the ceiling to have effective thermal-energy storage by absorbing the substantial heat gain from the internal heat sources.

关键词： latent heat sodium sulphate decahydrate phase-change material transportation thermal-energy storage

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Investigation of heat transfer of a building wall in the presence of phase change material(PCM)

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Energy and Built Environment 2020年第2期1卷 199-206页

作者： Rafid Jahangir Khan md.Zubayer hossain Bhuiyan dewan Hasan Ahmed Department of Mechanical and Production Engineering Ahsanullah University of Science and Technology141-142 Love RoadTejgaon Industrial AreaDhakaBangladesh

The energy consumption in buildings for heating,ventilation,and air-conditioning is increasing with the in-creasing demand for thermal *** energy storage with phase change material(PCM)has attracted growing attention for its role in achieving energy conservation in buildings with thermal *** paper investigates the effect of PCM on the heat transfer rate in a building wall and the role of PCM on the indoor thermal comfort of the *** models of building wall fragments were developed for the experimental *** one model,tests were conducted for different positions of the PCM layer in the building wall to identify the optimal position of the PCM layer inside the *** another model,tests were carried out integrating PCM,air gap,and other conventional building materials(brickbat and sand),one at a time,to investigate the role of PCM on the heat transfer rate in the building wall *** results show that placing the PCM layer closer to the heat source gives a low-temperature gain of the cold water bath(indoor state)as compared with the PCM layer near the heat *** PCM,the temperature rise of the cold water bath(indoor state)of the building wall fragment was the lowest,and the slope of the temperature rise of the cold water bath becomes steadier with time i.e.,fewer temperature *** was a significant time delay for the cold water bath to reach a given *** heat required for a unit degree increase in the temperature of the cold water bath was higher and the peak heat flux of the wall was lower relative to the other building materials.

关键词： Phase change material(PCM) Thermal energy storage Building wall fragment Thermal comfort

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Low Altitude Satellite Constellation for Futuristic Aerial-Ground Communications

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Computer Modeling in Engineering & Sciences 2023年第8期136卷 1053-1089页

作者： Saifur Rahman Sabuj Mohammad Saadman Alam Majumder Haider md Akbar hossain Al-sakib Khan Pathan Department of Electronic Engineering Hanbat National UniversityDaejeon34158South Korea Department of Electrical and Electronic Engineering Brac UniversityDhaka1212Bangladesh School of Business and Digital Technologies Manukau Institute of TechnologyManukau2241New Zealand Department of Computer Science and Engineering United International UniversityDhaka1212Bangladesh

This paper discusses the significance and prospects of low altitude small satellite aerial vehicles to ensure smooth aerial-ground communications for next-generation broadband *** achieve the generic goals of fifthgeneration and beyondwireless networks,the existing aerial network architecture needs to be *** detailed architecture of low altitude aerial networks and the challenges in resource management have been illustrated in this ***,we have studied the coordination between promising communication technologies and low altitude aerial networks to provide robust network *** talk about the techniques that can ensure userfriendly control and monitoring of the low altitude aerial networks to bring forth wireless broadband connectivity to a new *** the end,we highlight the future research directions of aerial-ground communications in terms of access technologies,machine learning,compressed sensing,and quantum communications.

关键词： Aerial-terrestrial network cognitive radio network cooperative communication high altitude platform low altitude platform low earth orbit satellite constellation unmanned aerial vehicle

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LDNet: A Robust Hybrid Approach for Lie Detection Using Deep Learning Techniques

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Computers, Materials & Continua 2024年第11期81卷 2845-2871页

作者： Shanjita Akter Prome md Rafiqul Islam md.Kowsar hossain sakib David Asirvatham Neethiahnanthan Ari Ragavan Cesar Sanin Edward Szczerbicki School of Computer Science Taylor’s UniversitySubang Jaya47500Malaysia Information Systems Australian Institute of Higher EducationSydneyNSW 2000Australia Faculty of Social Sciences&Leisure Management Taylor’s UniversitySubang Jaya47500Malaysia Faculty of Management and Economics Gdansk University of TechnologyGdansk80-233Poland

Deception detection is regarded as a concern for everyone in their daily lives and affects social *** human face is a rich source of data that offers trustworthy markers of *** deception or lie detection systems are non-intrusive,cost-effective,and mobile by identifying facial *** the last decade,numerous studies have been conducted on deception detection using several advanced *** have focused their attention on inventing more effective and efficient solutions for the detection of ***,it could be challenging to spot trends,practical approaches,gaps,and chances for ***,there are still a lot of opportunities for innovative deception detection ***,we used a variety of machine learning(ML)and deep learning(DL)approaches to experiment with this *** research aims to do the following:(i)review and analyze the current lie detection(LD)systems;(ii)create a dataset;(iii)use several ML and DL techniques to identify lying;and(iv)create a hybrid model known as *** combining layers from Vgg16 and DeneseNet121,LDNet was developed and offered the best accuracy(99.50%)of all the *** developed hybrid model is a great addition that significantly advances the study of *** findings from this research endeavor are expected to advance our understanding of the effectiveness of ML and DL techniques in ***,it has significant practical applications in diverse domains such as security,law enforcement,border control,organizations,and investigation cases where accurate lie detection is paramount.

关键词： Artificial intelligence deception/lie detection deep learning facial expression machine learning

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Scalable Process to Develop Durable Conductive Cotton Fabric

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Advanced Fiber Materials 2020年第6期2卷 291-301页

作者： md.Abdullah Al.Mamun md.Touhidul Islam md.Momtaz Islam Kazi Sowrov md.Afzal hossain dewan Murshed Ahmed Hasan Shahariar Bangladesh University of Textiles Dhaka 1208Bangladesh University of Manchester ManchesterUK Funxion Wear IncRaleighNC 27606USA

Developing a scalable process is critical to manufacture conductive fabric for commercial *** paper describes a scalable coating process that is compatible with existing industrial finishing processes of *** this process,the fabric is continuously dipped in water-based metal salt and the reducing agent solution to impart conductive particles on the fiber *** 10 consecutive cycles of dip coating,the fabric shows 6Ω/*** *** process is tuned to minimize process cost and material cost,and maximize the durability of the *** paper also introduces an easy protective coating technique of the conductive fabric that improves the durability of the conductive fabric without sacrificing the comfort properties of textile fabrics such as breathability and *** encapsulated conductive fabric shows good air-permeability and it is 6.96 cm^(3)/cm^(2)/***,the conductivity of the encapsulated fabric is quite stable after four accelerated washing ***,the fabric remains conductive on the surfaces and is suitable for using as a conductive track and connectors.

关键词： Conductive fabric Scalable process Layer by layer deposition Durability

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Ensemble learning of diffractive optical networks

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Light(Science & Applications) 2021年第1期10卷 123-135页

作者： md Sadman sakib Rahman Jingxi Li Deniz Mengu Yair Rivenson Aydogan Ozcan Electrical and Computer Engineering Department University of CaliforniaLos AngelesCA 90095USA Bioengineering Department University of CaliforniaLos AngelesCA 90095USA California NanoSystems Institute(CNSI) University of CaliforniaLos AngelesCA 90095USA

A plethora of research advances have emerged in the fields of optics and photonics that benefit from harnessing the power of machine ***,there has been a revival of interest in optical computing hardware due to its potential advantages for machine learning tasks in terms of parallelization,power efficiency and computation *** deep neural networks(D^(2)NNs)form such an optical computing framework that benefits from deep learning-based design of successive diffractive layers to all-optically process information as the input light diffracts through these passive layers.D^(2)NNs have demonstrated success in various tasks,including object classification,the spectral encoding of information,optical pulse shaping and ***,we substantially improve the inference performance of diffractive optical networks using feature engineering and ensemble *** independently training 1252 D^(2)NNs that were diversely engineered with a variety of passive input filters,we applied a pruning algorithm to select an optimized ensemble of D^(2)NNs that collectively improved the image classification *** this pruning,we numerically demonstrated that ensembles of N=14 and N=30 D^(2)NNs achieve blind testing accuracies of 61.14±0.23%and 62.13±0.05%,respectively,on the classification of GFAR-10 test images,providing an inference improvennent of>16%compared to the average performance of the individual D^(2)NNs within each *** results constitute the highest inference accuracies achieved to date by any diffractive optical neural network design on the same dataset and might provide a significant leap to extend the application space of diffractive optical image classification and machine vision systems.

关键词： networks collective successive

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Universal linear intensity transformations using spatially incoherent diffractive processors

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Light(Science & Applications) 2023年第9期12卷 1830-1856页

作者： md Sadman sakib Rahman Xilin Yang Jingxi Li Bijie Bai Aydogan Ozcan Electrical and Computer Engineering Department University of CaliforniaLos AngelesCA 90095USA Bioengineering Department University of CaliforniaLos AngelesCA 90095USA California NanoSystems Institute(CNSI) University of CaliforniaLos AngelesCA 90095USA

Under spatially coherent light,a diffractive optical network composed of structured surfaces can be designed to perform any arbitrary complex-valued linear transformation between its input and output fields-of-view(FOVs)if the total number(N)of optimizable phase-only diffractive features is≥~2N_(i)N_(o),where Ni and No refer to the number of useful pixels at the input and the output FOVs,*** we report the design of a spatially incoherent diffractive optical processor that can approximate any arbitrary linear transformation in time-averaged intensity between its input and output *** spatially incoherent monochromatic light,the spatially varying intensity point spread function(H)of a diffractive network,corresponding to a given,arbitrarily-selected linear intensity transformation,can be written as H(m,n;m′,n′)=|h(m,n;m′,n′)|^(2),where h is the spatially coherent point spread function of the same diffractive network,and(m,n)and(m′,n′)define the coordinates of the output and input FOVs,*** numerical simulations and deep learning,supervised through examples of input-output profiles,we demonstrate that a spatially incoherent diffractive network can be trained to all-optically perform any arbitrary linear intensity transformation between its input and output if N≥~2N_(i)N_(o).We also report the design of spatially incoherent diffractive networks for linear processing of intensity information at multiple illumination wavelengths,operating ***,we numerically demonstrate a diffractive network design that performs all-optical classification of handwritten digits under spatially incoherent illumination,achieving a test accuracy of>95%.Spatially incoherent diffractive networks will be broadly useful for designing all-optical visual processors that can work under natural light.

关键词： spatially intensity arbitrary

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Potential Benefits of Bioactive Compounds of Traditional Rice Grown in South and Southeast Asia:A Review

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Rice science 2023年第6期30卷 537-551页

作者： md.Forshed dewan md.AHIDUZZAMAN md.Nahidul ISLAM Habibul Bari SHOZIB Department of Agro-Processing Bangabandhu Sheikh Mujibur Rahman Agricultural UniversityGazipur 1706Bangladesh Institute of Food Safety and Processing Bangabandhu Sheikh Mujibur Rahman Agricultural UniversityGazipur 1706Bangladesh Grain Quality and Nutrition Division Bangladesh Rice Research InstituteGazipur 1701Bangladesh

Traditional rice varieties have been widely cultivated and popularly consumed by Asian people for a very long time and have recently garnered increased consumer *** or indigenous rice varieties are known to be rich in a wide range of bioactive compounds,particularly phenolic compounds,flavonoids,tannins,anthocyanins,proanthocyanidins,phytic acids,andγ-*** have identified 32 phenolic acids,including hydroxycinnamic acid derivatives,and 7 different flavonoids in rice *** bioactive compounds have unique physiological effects on human ***,rice grains exhibit nutraceutical potential for antidiabetic,antiarthritic,anti-inflammatory,antibacterial,and antitumor *** this review,we critically analyzed the bioactive components of traditional rice and their nutraceutical potential in protecting against harmful microbial *** ensure that future generations have access to these beneficial substances,it is crucial to preserve traditional rice varieties.

关键词： antioxidant activity health promoting compound indigenous rice pigmented rice

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Chitosan based bioactive materials in tissue engineering applications-A review

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Bioactive Materials 2020年第1期5卷 164-183页

作者： md.Minhajul Islam md.Shahruzzaman Shanta Biswas md.Nurus sakib Taslim Ur Rashid Department of Applied Chemistry and Chemical Engineering Faculty of Engineering and TechnologyUniversity of DhakaDhaka1000Bangladesh Fiber and Polymer Science North Carolina State UniversityCampus Box 7616RaleighNC27695United States

In recent years,there have been increasingly rapid advances of using bioactive materials in tissue engineering *** materials constitute many different structures based upon ceramic,metallic or polymeric materials,and can elicit specific tissue ***,most of them are relatively brittle,stiff,and difficult to form into complex ***,there has been a growing demand for preparing materials with tailored physical,biological,and mechanical properties,as well as predictable degradation ***-based materials have been shown to be ideal bioactive materials due to their outstanding properties such as formability into different structures,and fabricability with a wide range of bioactive materials,in addition to their biocompatibility and *** review highlights scientific findings concerning the use of innovative chitosan-based bioactive materials in the fields of tissue engineering,with an outlook into their future *** also covers latest developments in terms of constituents,fabrication technologies,structural,and bioactive properties of these materials that may represent an effective solution for tissue engineering materials,making them a realistic clinical alternative in the near future.

关键词： Chitosan Bioactive material Scaffold Tissue engineering

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