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joint inventory and transshipment decisions with consumer behavioral heterogeneity

管理科学学报:英文版 2023年第3期8卷 369-385页

作者： Pingping Feng jian Chai Zhongquan Hu Wei Zong Feng Wu devin j.wang School of Economics and Management Xidian UniversityXi'an710126China b School of ManagementXi'an Jiaotong UniversityXi'an710049China Department of Managament Scinece and Information Systems Rutgers UniversityPiscatawayNJ08854USA

Transshipment is an effective method for reducing mismatches between supply and demand among *** attempting to purchase out-of-stock items may wait for transshipment,purchase at another store,or choose not to *** this paper,the consumer behavioral heterogeneity is characterized using the transshipment request rate and consumer switching *** affects the replenishment and transshipment decisions,as well as the system *** inventory replenishment and transshipment decisions are studied in both centralized and decentralized two-location inventory systems with consumer behavioral *** characterize optimal replenishment decisions in a centralized system,prove the existence of a unique Nash equilibrium in a decentralized system with a specific demand distribution,and determine the coordinating transshipment price for some decentralized *** numerical studies,the performance of various systems is analyzed for consumers with identical(symmetric)or differing(asymmetric)behavior between *** scenarios with symmetric consumers,a higher transshipment request rate and consumer switching rate resulted in increased total profit in all *** scenarios with asymmetric consumers,the retailer with the higher consumer switching rate should reduce ordering in a centralized system but increase ordering in a decentralized ***,the retailer with the higher transshipment request rate reduces ordering to increase profit,whereas the other retailer increases order quantity yet earns less profit.

关键词： Inventory management Lateral transshipment Nash equilibrium Consumer behavior

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Optimal timing and route of nutritional support after esophagectomy: A review of the literature

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World journal of Gastroenterology 2019年第31期25卷 4427-4436页

作者： Richard Zheng Courtney L devin Michael j Pucci Adam C Berger Ernest L Rosato Francesco Palazzo Department of Surgery Thomas Jefferson University Hospital.Sidney Kimmel Medical College Philadelphia University and Thomas Jefferson University

Some controversy surrounds the postoperative feeding regimen utilized in patients who undergo *** in practices during the perioperative period exists including the type of nutrition started,the delivery route,and its *** nutrition is essential for this patient population as these patients often present with weight loss and have altered eating patterns after surgery,which can affect their ability to regain or maintain *** of feeding after an esophagectomy include total parenteral nutrition,nasoduodenal/nasojejunal tube feeding,jejunostomy tube feeding,and oral *** evidence suggests that early oral feeding is associated with shorter LOS,faster return of bowel function,and improved quality of *** recovery pathways after surgery pathways after esophagectomy with a component of early oral feeding also seem to be safe,feasible,and cost-effective,albeit with limited ***,data on anastomotic leaks is mixed,and some studies suggest that the incidence of leaks may be higher with early oral *** risk of anastomotic leak with early feeding may be heavily modulated by surgical *** definitive data is currently available to definitively answer this question,and further studies should look at how these early feeding regimens vary by surgical *** review aims to discuss the existing literature on the optimal route and timing of feeding after esophagectomy.

关键词： Esophagectomy Oral feeding Early feeding Delayed feeding Enteral nutrition Esophageal cancer jejunostomy tube Postoperative complications

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From oral formulations to drug-eluting implants:using 3D and 4D printing to develop drug delivery systems and personalized medicine

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Bio-Design and Manufacturing 2022年第1期5卷 85-106页

作者： Niels G.A.Willemen Margaretha A.j.Morsink devin Veerman Classius F.da Silva juliana C.Cardoso Eliana B.Souto Patrícia Severino Center for Biomedical Engineering Department of MedicineBrigham and Women&HospitalHarvard Medical School65 Landsdowne StreetMA 02139 CambridgeUSA Department of Developmental BioEngineering Faculty of Science and TechnologyTechnical Medical CentreUniversity of TwenteEnschedeThe Netherlands Translational Liver Research Department of Medical Cell BioPhysicsTechnical Medical CentreFaculty of Science and TechnologyUniversity of TwenteEnschedeThe Netherlands Targeted Therapeutics Department of Biomaterials Science and TechnologyFaculty of Science and TechnologyUniversity of TwenteEnschedeThe Netherlands Department of Chemical Engineering Institute of EnvironmentalChemical and Pharmaceutical SciencesFederal University of São PauloRua São Nicolau210Diadema 09913‑030Brazil University of Tiradentes(Unit) and Institute of Technology and Research(ITP)Av.Murilo Dantas300Aracaju 49010‑390Brazil Faculty of Pharmacy University of CoimbraPólo das Ciências da SaúdeAzinhaga de Santa Comba3000‑548 CoimbraPortugal CEB‑Centre of Biological Engineering University of MinhoCampus de Gualtar4710‑057 BragaPortugal Tiradentes Institute 150 Mt Vernon StDorchesterMA 02125USA

Since the start of the Precision Medicine Initiative by the United States of America in 2015,interest in personalized medicine has grown *** short,personalized medicine is a term that describes medical treatment that is tuned to the *** possible way to realize personalized medicine is 3D *** using materials that can be tuned upon stimulation,4D printing is *** recent years,many studies have been exploring a new field that combines 3D and 4D printing with *** has resulted in many concepts of pharmaceutical devices and formulations that can be printed and,possibly,tailored to an ***,the first 3D printed drug,Spritam®,has already found its way to the *** review gives an overview of various 3D and 4D printing techniques and their applications in the pharmaceutical field as drug delivery systems and personalized medicine.

关键词： Drug delivery systems 3D/4D printing Drug-eluting implants Microneedles Oral formulations

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Sensorized tissue analogues enabled by a 3D-printed conductive organogel

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npj Flexible Electronics 2021年第1期5卷 51-58页

作者： Michael R.Crump Sophia L.Bidinger Felippe j.Pavinatto Alex T.Gong Robert M.Sweet devin MacKenzie Department of Materials Science&Engineering University of WashingtonSeattleWAUSA Center for Research in Education and Simulation Technologies University of WashingtonSeattleWAUSA Department of Surgery University of WashingtonSeattleWAUSA Department of Mechanical Engineering University of WashingtonSeattleWAUSA

State-of-the-art tissue analogues used in high-fidelity,hands-on medical simulation modules can deliver lifelike appearance and feel but lack the capability to provide quantified,real-time assessment of practitioner *** monolithic fabrication of hybrid printed/textile piezoresistive strain sensors in a realistic Y/V plasty suture training pad is demonstrated.A class of 3D-printable organogels comprised of inexpensive and nonhazardous feedstocks is used as the sensing medium,and conductive composite threads are used as the *** organogels are comprised of a glycol-based deep-eutectic solvent(DES)serving as the ionic conductor and 3-trimethoxysilylmethacrylate-capped fumed silica particles serving as the gelating *** measurements reveal the influence of fumed silica particle capping group on the mixture *** strain sensors demonstrate a maximum strain amplitude of 300%,negligible signal drift,a monotonic sensor response,a low degree of hysteresis,and excellent cyclic *** increased contact resistance of the conductive thread electrodes used in place of wire electrodes do not make a significant impact on sensor *** work showcases the potential of these organogels utilized in sensorized tissue analogues and freestanding strain sensors for widespread applications in medical simulation and education.

关键词： stability analogues conductive

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The Effects of Low Intensity Endurance Activity on Various Physiological Parameters and Exercise Induced Oxidative Stress in Dogs

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Open journal of Veterinary Medicine 2014年第7期4卷 134-144页

作者： janice L. Huntingford Corri B. Levine Debbie j. Mustacich devin Corrigan Robert L. Downey joseph j. Wakshlag Annamaet Petfood Company Sellersville PA USA Department of Clinical Sciences Cornell University Ithaca NY USA Essex Animal Hospital Essex Canada Linus Pauling Institute Oregon State University Corvallis OR USA

The study of canine athlete physiology has focused on endurance sled dog racing and high intensity short duration Greyhound racing, yet the number of dogs competing in low intensity endurance activities is rising due to the increased numbers of hunting and companion dog activities. There is little information on the physiological effect of longer duration low intensity endurance activities. We set out to evaluate the serum biochemistry, oxidative stress, and cortisol response before and after two consecutive days of exercise in ten healthy unconditioned male dogs. Exercise sessions consisted of 120 minutes on an exercise wheel at 11 km/hour on 2 consecutive days. Blood was collected at four time points: 24 hours pre-exercise (sample 1, Day 0, resting);2 min post-exercise on days 1 and 2, (samples 2 and 3, respectively);and 20 hours post-exercise, collected on day 3(sample 4). Hematocrit, blood gases, serum chemistry, uric acid, cortisol, and F2-isoprostanes were determined. Serum biochemistry and hematocrit suggested hemoconcentration, mild muscle damage and respiratory alkalosis during exercise, which was expected in the unconditioned canine athlete. In addition, plasma indices of oxidative damage (F2-isoprostanes) increased, as did plasma uric acid (an endogenous antioxidant). Importantly, similar to human studies, plasma F2-isoprostanes decreased 24 hours after exercise suggesting a protective effect of exercise. Serum cortisol concentrations were also markedly elevated at the end of exercise on both days suggesting that timing of sampling may play a role in interpreting cortisol results when looking at previous field studies.

关键词： Exercise Cortisol Isoprostane Dehydration Uric Acid

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超体质量减肥手术后体形塑造术的并发症：术后处理和治疗

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中国美容整形外科杂志 2013年第7期24卷 I0022-I0022页

作者： joseph Michaels V devin Coon j. Peter Rubin 朱丽娜(译) 魏峰(译) 高景恒(译) 张晨(译) 私人诊所美国马里兰州巴尔的摩和北贝塞斯达美国约翰霍普金斯医疗机构颌面整形和再造外科匹兹堡大学医学中心整形和再造外科美国宾夕法尼亚州匹兹堡《中国美容整形外科杂志》编辑部大连大学附属新华医院

【摘要】体形塑造患者适当的术后管理对术后远期的满意结果是必不可少的。普遍问题，如引流管处理、营养和活动限制，与所有患者均相关。尽管术后并发症十分罕见，但本文描述的处理轻度并发症的有效措施也是非常有价值的。

关键词：术后并发症体形塑造术后处理超体质量手术后治疗减肥术后管理

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超体质量减肥手术后体形塑造术并发症：评估和预防策略

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中国美容整形外科杂志 2013年第7期24卷 I0022-I0022页

作者： joseph Michaels V devin Coon j. Peter Rubin 朱丽娜(译) 魏峰(译) 高景恒(译) 张晨(译) 美国马里兰州北贝塞斯达巴尔的摩匹兹堡《中国美容整形外科杂志》编辑部大连大学附属新华医院

【摘要】体质量大量减轻的患者对整形医师来说是一个特别的挑战。回顾这些问题，对不是专门研究该领域的外科医师是有价值的。手术要想取得良好结果，需要综合的围手术方法、开始时正确的患者选择和正确的手术预期。术中注意事项（如低... 详细信息

【摘要】体质量大量减轻的患者对整形医师来说是一个特别的挑战。回顾这些问题，对不是专门研究该领域的外科医师是有价值的。手术要想取得良好结果，需要综合的围手术方法、开始时正确的患者选择和正确的手术预期。术中注意事项（如低体温症的预防和血栓栓塞的预防）对改善结果和降低发病率均有积极作用。适当的术后护理可让患者和医师对结果都满意。

关键词：预防策略超体质量手术后术并发症体形塑造减肥术中注意事项整形医师

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超体质量减肥手术后体形塑造术的低体温症和并发症

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中国美容整形外科杂志 2013年第7期24卷 I0024-I0024页

作者： devin Coon joseph Michaels 5th jeffrey A. Gusenoff Tae Chong Chad Purnell j. Peter Rubin 朱丽娜(译) 魏峰(译) 高景恒(译) 张晨(译) 美国约翰霍普金斯医院整形和再造外科美国马里兰州巴尔的摩和贝塞斯达匹兹堡大学医学院整形和再造外科部外科系美国宾夕法尼亚州匹兹堡德克萨斯州西南医学中心整形和再造外科美国德克萨斯州达拉斯《中国美容整形外科杂志》编辑部大连大学附属新华医院

背景超体质量减肥手术后的体形塑造是一个迅速增长的领域。因为手术时间长和轻度并发症发生率较高，需要循证医学指导手术管理。目前，关于围手术期因素对患者结果影响的数据分析很有限。方法纳入体质量减轻50磅以上，且行体形塑造术的... 详细信息

背景超体质量减肥手术后的体形塑造是一个迅速增长的领域。因为手术时间长和轻度并发症发生率较高，需要循证医学指导手术管理。目前，关于围手术期因素对患者结果影响的数据分析很有限。方法纳入体质量减轻50磅以上，且行体形塑造术的患者。所有手术均由资深专家进行，

关键词：并发症发生率体形塑造超体质量手术后低体温症减肥围手术期因素体质量减轻

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Immunity:研究开发出最优的HIV疫苗递送模式

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现代生物医学进展 2017年第27期17卷 I0003-I0003页

作者： Matthias Pauthner Colin Havenar-Daughton devin Sok joseph P. Nkolola Raiza Bastidas Archana V. Boopathy Diane G. Carnathan Abishek Chandrashekar Kimberly M. Cirelli Christopher A. Cottrell Alexey M. Eroshkin javier Guenaga Kirti Kaushik Daniel W. Kulp jinyan Liu Laura E. McCoy Aaron L. Oom Gabriel Ozorowski Kai W. Post Shailendra K. Sharma jon M. Steichen Steven W. de Taeye Talar Tokatlian Alba Torrents de la Peña Salvatore T. Butera Celia C. LaBranche David C. Montefiori Guido Silvestri Ian A. Wilson Darrell j. Irvine Rogier W. Sanders William R. Schief Andrew B. Ward Richard T. Wyatt Dan H. Barouch Shane Crotty Dennis R. Burton University of California San Diego La Jolla CA 92093 USA

HIV已不再占据头条新闻。这主要是因为抗逆转录病毒药物的成功开发已将HIV病毒感染导致的艾滋病（AIDS）转化为一种慢性的可控制的疾病。然而。当前在全世界大约0．367亿名HIV感染者中，仅约一半的人能够获得控制这种病毒所需的药物。... 详细信息

HIV已不再占据头条新闻。这主要是因为抗逆转录病毒药物的成功开发已将HIV病毒感染导致的艾滋病（AIDS）转化为一种慢性的可控制的疾病。然而。当前在全世界大约0．367亿名HIV感染者中，仅约一半的人能够获得控制这种病毒所需的药物。与此同时。新的HIV感染率持续保持在非常高的水平，这突出强调了需要开发一种预防性疫苗。然而，几十年来。

关键词： HIV感染者研究开发疫苗递送病毒感染逆转录病毒艾滋病感染率

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