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Training The Traders

ChinAfrica 2023年第1期15卷 40-41页

作者： derrick SILIMINA 不详

China-sponsored centre in Djibouti is providing crucial know-how to young entrepreneurs in Africa Evans Otieno,34,is the perfect embodiment of a true go-getter,as reflected in his success in perfecting the art of making money through cross-border *** from the humble beginning of being a street vendor in Naivasha Town,northwest of Nairobi,Kenya’s capital,he has now become an automotive dealer who supplies spare parts to garage owners in Nairobi’s central business district.

关键词： perfect northwest Training

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A Fair to Find Jobs

ChinAfrica 2022年第12期14卷 40-41页

作者： derrick SILIMINA 不详

Chinese job expo helps Zambian youths access to employment Armed with their resumes,over 200 job-seekers,who were mostly young graduates of the Confucius Institute at the University of Zambia(UNZA)and other institutions of higher learning in the country,prowled the lush grounds of the university’s Great East Road campus of the university,looking for signs of job openings.

关键词： resume looking mostly

Un salon de l'emploi efficace

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中国与非洲（法文版） 2022年第10期14卷 42-43页

作者： derrick SILIMINA 不详

Latech au service de la sécurité alimentaire Les machines agricoles chinoises donnent un coup de pouce à I'agriculture au Zimbabwe

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中国与非洲（法文版） 2022年第4期14卷 44-45页

作者： derrick SILIMINA 不详

Le puits de la réussite L'accès aux produits chinois dynamise les PME en Zambie

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中国与非洲（法文版） 2023年第12期15卷 38-39页

作者： derrick SILIMINA 不详

Contribuer à l'industrialisation:Un centre finance parla Chine forme des ingenieurs ougandais

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中国与非洲（法文版） 2022年第9期14卷 36-37页

作者： derrick SILIMINA 不详

Élargir I'accès aune éducation de qualite

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中国与非洲（法文版） 2022年第5期14卷 40-41页

作者： derrick SILIMINA 不详

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Échafauder l’avenir

中国与非洲（法文版） 2023年第4期15卷 46-47页

作者： derrick SILIMINA 不详

Rational design of oral drugs targeting mucosa delivery with gut organoid platforms

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Bioactive Materials 2023年第12期30卷 116-128页

作者： Tianjian Tong Yijun Qi derrick Rollins Luke D.Bussiere Debarpan Dhar Cathy L.Miller Chenxu Yu Qun Wang Department of Agricultural Biosystem and Engineering Iowa State UniversityAmesIAUSA Department of Chemical and Biological Engineering Iowa State UniversityAmesIAUSA Department of Veterinary Microbiology and Preventive Medicine College of Veterinary MedicineIowa State UniversityAmesIAUSA Interdepartmental Microbiology Program Iowa State UniversityAmesIAUSA Department of Statistics Iowa State UniversityAmesIAUSA

Effective oral drugs and vaccines require high delivery efficiency across the gastrointestinal epithelia and protection of medically effective payloads(i.e.,immunogens)against gastric *** this study,hollowed nanocarriers(NCs:silica nanospheres and gold nanocages)with poly-l-lysine(PLL)coating and mammalian orthoreovirus cell attachment proteinσ1 functionalization(NC-PLL-σ1)were explored as functional oral drug delivery vehicles(ODDVs).The transport of these ODDVs to mucosal lymphoid tissues could be facilitated by microfold cells(M-cells)mediated transcytosis(viaσ1-α2–3-linked sialic acids adherence)across gastrointestinal *** coating provided protection and slow-release of rhodamine 6 G(R6G),a model *** transport effectiveness of these ODDVs was tested on intestinal organoid monolayers in *** compared with other experimental groups,the fully functionalized ODDV system(with PLL-σ1)demonstrated two significant advantages:a significantly higher transport efficiency(198%over blank control at 48 h);and protection of payloads which led to both better transport efficiency and extended-release of payloads(61%over uncoated carriers at 48 h).In addition,it was shown that the M cell presence in intestinal organoid monolayers(modulated by Rank L stimulation)was a determining factor on the transport efficiency of the ODDVs:more M-cells(induced by higher Rank L)in the organoid monolayers led to higher transport efficiency for ODDV-delivered model payload(R6G).The fully functionalized ODDVs showed great potential as effective oral delivery vehicles for drugs and vaccines.

关键词： Oral drug delivery vehicles Organoids Biomimetic virus Sigma 1 protein Gold and silica nanoparticles