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Amplitude analysis of the decays D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)

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Chinese physics C 2024年第8期48卷 6-33页

作者： M.Ablikim M.N.Achasov p.Adlarson O.Afedulidis X.C.Ai R.Aliberti A.Amoroso Q.An Y.Bai O.Bakina I.Balossino Y.Ban H.-R.Bao V.Batozskaya k.Begzsuren N.Berger M.Berlowski M.Bertani D.Bettoni F.Bianchi E.Bianco A.Bortone I.Boyko R.A.Briere A.Brueggemann H.Cai X.Cai A.Calcaterra G.F.Cao N.Cao S.A.Cetin J.F.Chang W.L.Chang G.R.Che G.Chelkov C.Chen C.H.Chen Chao Chen G.Chen H.S.Chen M.L.Chen S.J.Chen S.L.Chen S.M.Chen T.Chen X.R.Chen X.T.Chen Y.B.Chen Y.Q.Chen Z.J.Chen Z.Y.Chen S.k.Choi X.Chu G.Cibinetto F.Cossio J.J.Cui H.L.Dai J.p.Dai A.Dbeyssi R.E.de Boer D.Dedovich C.Q.Deng Z.Y.Deng A.Denig I.Denysenko M.Destefanis F.De Mori B.Fang S.S.Fang W.X.Fang Y.Fang Y.Q.Fang R.Farinelli L.Fava F.Feldbauer G.Felici C.Q.Feng J.H.Feng Y.T.Feng k.Fischer M.Fritsch C.D.Fu J.L.Fu Y.W.Fu H.Gao Y.N.Gao Yang Gao S.Garbolino I.Garzia p.T.Ge Z.W.Ge C.Geng E.M.Gersabeck B.Ding X.X.Ding Y.Ding Y.Ding J.Dong L.Y.Dong M.Y.Dong X.Dong M.C.Du S.X.Du Z.H.Duan p.Egorov Y.H.Fan J.Fang JA.Gilman k.Goetzen L.Gong W.X.Gong W.Gradl S.Gramigna M.Greco M.H.Gu Y.T.Gu C.Y.Guan Z.L.Guan A.Q.Guo L.B.Guo M.J.Guo R.p.Guo Y.p.Guo A.Guskov J.Gutierrez k.L.Han T.T.Han X.Q.Hao F.A.Harris k.k.He k.L.He F.H.Heinsius C.H.Heinz Y.k.Heng C.Herold T.Holtmann p.C.Hong G.Y.Hou X.T.Hou Y.R.Hou Z.L.Hou B.Y.Hu H.M.Hu J.F.Hu T.Hu Y.Hu G.S.Huang k.X.Huang L.Q.Huang X.T.Huang Y.p.Huang T.Hussain F.H\"olzken N.H\"usken N.in der Wiesche M.Irshad J.Jackson S.Janchiv J.H.Jeong Q.Ji Q.p.Ji W.Ji X.B.Ji X.L.Ji Y.Y.Ji X.Q.Jia Z.k.Jia D.Jiang H.B.Jiang p.C.Jiang S.S.Jiang T.J.Jiang X.S.Jiang Y.Jiang J.B.Jiao J.k.Jiao Z.Jiao S.Jin Y.Jin M.Q.Jing X.M.Jing T.Johansson S.kabana N.kalantar-Nayestanaki X.L.kang X.S.kang M.kavatsyuk B.C.ke V.khachatryan A.khoukaz R.kiuchi O.B.kolcu B.kopf M.kuessner X.kui A.kupsc W.k\"uhn J.J.Lane p.Larin L.Lavezzi T.T.Lei Z.H.Lei H.Leithoff M.Lellmann T.Lenz C.Li C.Li C.H.Li Cheng Li D.M.Li F.Li G.Li H.Li H.B.Li H.J.Li H.N.Li Hui Li J.R.Li J.S.Li k.Li L.J.Li L.k.Li Lei Li M.H.Li p.R.Li Q.M.Li Q.X.Li R.Li S.X.Li T.Li W.D.Li W.G.Li X.Li X.H.Li X.L.Li X.Y.Li Y Institute of High Energy physics Chinese Academy of SciencesBeijing 100049China Beihang University Beijing 100191China Bochum Ruhr-University D-44780 BochumGermany Budker Institute of Nuclear physics SB RAS(BINp) Novosibirsk 630090Russia Carnegie Mellon University PittsburghPennsylvania 15213USA Central China Normal University Wuhan 430079China Central South University Changsha 410083China China Center of Advanced Science and Technology Beijing 100190China China University of Geosciences Wuhan 430074China Chung-Ang University Seoul06974Republic of Korea COMSATS University Islamabad Lahore CampusDefence RoadOff Raiwind Road54000 LahorePakistan Fudan University Shanghai 200433China GSI Helmholtzcentre for Heavy Ion Research GmbH D-64291 DarmstadtGermany Guangxi Normal University Guilin 541004China Guangxi University Nanning 530004China Hangzhou Normal University Hangzhou 310036China Hebei University Baoding 071002China Helmholtz Institute Mainz Staudinger Weg 18D-55099 MainzGermany Henan Normal University Xinxiang 453007China Henan University Kaifeng 475004China Henan University of Science and Technology Luoyang 471003China Henan University of Technology Zhengzhou 450001China Huangshan College Huangshan 245000China Hunan Normal University Changsha 410081China Hunan University Changsha 410082China Indian Institute of Technology Madras Chennai 600036India Indiana University BloomingtonIndiana 47405USA INFN Laboratori Nazionali di Frascati INFN Laboratori Nazionali di FrascatiI-00044FrascatiItaly INFN Laboratori Nazionali di Frascati INFN Sezione di PerugiaI-06100PerugiaItaly INFN Laboratori Nazionali di Frascati University of PerugiaI-06100PerugiaItaly INFN Sezione di Ferrara INFN Sezione di FerraraI-44122FerraraItaly INFN Sezione di Ferrara University of FerraraI-44122FerraraItaly Inner Mongolia University Hohhot 010021China Institute of Modern physics Lanzhou 730000China Institute of physics and Technology Peace Avenue 54BUlaanbaatar 13330Mongolia Instituto de A

Using e^(+)e^(−)annihilation data corresponding to an integrated luminosity of 2.93 fb^(−1)taken at the center-of-mass energy√s=3.773 GeV with the BESIII detector,a joint amplitude analysis is performed on the decays D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)(non-η).The fit fractions of individual components are obtained,and large interferences among the dominant components of the decays D^(0)→a_(1)(1260)π,D^(0)→π(1300)π,D^(0)→ρ(770)ρ(770),and D^(0)→2(ππ)_(S)are observed in both *** the obtained amplitude model,the Cp-even fractions of D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)(non-η)are determined to be(75.2±1.1_(stat).±1.5_(syst.))%and(68.9±1.5_(stat).±2.4_(syst.))%,*** branching fractions of D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)(non-η)are measured to be(0.688±0.010_(stat.)±0.010_(syst.))%and(0.951±0.025_(stat.)±0.021_(syst.))%,*** amplitude analysis provides an important model for the binning strategy in measuring the strong phase parameters of D^(0)→4πwhen used to determine the CkM angleγ(ϕ_(3))via the B^(−)→Dk^(−)decay.

关键词： BESIII D^(0)meson decays amplitude analysis Cp-even fraction

In-silico synthesis of lowest-pressure high-T_(c) ternary superhydrides

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npj Computational Materials 2022年第1期8卷 1119-1125页

作者： Roman Lucrezi Simone Di Cataldo Wolfgang von der Linden Lilia Boeri Christoph Heil Institute of Theoretical and Computational physics Graz University of TechnologyNAWI Graz8010GrazAustria Dipartimento di Fisica Sapienza Universitàdi Roma00185RomeItaly Enrico Fermi Research Center Via Panisperna 89 A00184RomeItaly

We report the theoretical prediction of two high-performing hydride superconductors BaSiH_(8)and SrSiH_(8).They are thermodynamically stable above pressures of 130 and 174 Gpa,respectively,and metastable below *** anharmonic phonon calculations,we determine the minimum pressures of dynamical stability to be around 3 Gpa for BaSiH8 and 27 Gpa for SrSiH_(8),and using the fully anisotropic Migdal-Eliashberg theory,we predict Tc’s around 71 and 126 k,*** also introduce a method to estimate the lowest pressure of synthesis,based on the calculation of the enthalpy barriers protecting the BaSiH_(8)Fm3¯m structure from decomposition at various *** kinetic pressure threshold is sensibly higher than the one based on dynamic stability,but gives a much more rigorous limit for synthesizability.

关键词： synthesis stability high

Determination of the number ofψ(3686)events taken at BESⅢ

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Chinese physics C 2024年第9期48卷 8-20页

作者： M.Ablikim M.N.Achasov p.Adlarson O.Afedulidis X.C.Ai R.Aliberti A.Amoroso Q.An Y.Bai O.Bakina I.Balossino Y.Ban H.-R.Bao V.Batozskaya k.Begzsuren N.Berger M.Berlowski M.Bertani D.Bettoni F.Bianchi E.Bianco A.Bortone I.Boyko R.A.Briere A.Brueggemann H.Cai X.Cai A.Calcaterra G.F.Cao N.Cao S.A.Cetin J.F.Chang G.R.Che G.Chelkov C.Chen C.H.Chen Chao Chen G.Chen H.S.Chen H.Y.Chen M.L.Chen S.J.Chen S.L.Chen S.M.Chen T.Chen X.R.Chen X.T.Chen Y.B.Chen Y.Q.Chen Z.J.Chen Z.Y.Chen S.k.Choi G.Cibinetto F.Cossio J.J.Cui H.L.Dai J.p.Dai A.Dbeyssi R.E.de Boer D.Dedovich C.Q.Deng Z.Y.Deng A.Denig I.Denysenko M.Destefanis F.De Mori B.Ding X.X.Ding Y.Ding Y.Ding J.Dong L.Y.Dong M.Y.Dong X.Dong M.C.Du S.X.Du Y.Y.Duan Z.H.Duan p.Egorov Y.H.Fan J.Fang J.Fang S.S.Fang W.X.Fang Y.Fang Y.Q.Fang R.Farinelli L.Fava F.Feldbauer G.Felici C.Q.Feng J.H.Feng Y.T.Feng M.Fritsch C.D.Fu J.L.Fu Y.W.Fu H.Gao X.B.Gao Y.N.Gao Yang Gao S.Garbolino I.Garzia L.Ge p.T.Ge Z.W.Ge C.Geng E.M.Gersabeck A.Gilman k.Goetzen L.Gong W.X.Gong W.Gradl S.Gramigna M.Greco M.H.Gu Y.T.Gu C.Y.Guan Z.L.Guan A.Q.Guo L.B.Guo M.J.Guo R.p.Guo Y.p.Guo A.Guskov J.Gutierrez k.L.Han T.T.Han F.Hanisch X.Q.Hao F.A.Harris k.k.He k.L.He F.H.Heinsius C.H.Heinz Y.k.Heng C.Herold T.Holtmann p.C.Hong G.Y.Hou X.T.Hou Y.R.Hou Z.L.Hou B.Y.Hu H.M.Hu J.F.Hu S.L.Hu T.Hu Y.Hu G.S.Huang k.X.Huang L.Q.Huang X.T.Huang Y.p.Huang T.Hussain F.Hölzken N.Hüsken N.in der Wiesche J.Jackson S.Janchiv J.H.Jeong Q.Ji Q.p.Ji W.Ji X.B.Ji X.L.Ji Y.Y.Ji X.Q.Jia Z.k.Jia D.Jiang H.B.Jiang p.C.Jiang S.S.Jiang T.J.Jiang X.S.Jiang Y.Jiang J.B.Jiao J.k.Jiao Z.Jiao S.Jin Y.Jin M.Q.Jing X.M.Jing T.Johansson S.kabana N.kalantar-Nayestanaki X.L.kang X.S.kang M.kavatsyuk B.C.ke V.khachatryan A.khoukaz R.kiuchi O.B.kolcu B.kopf M.kuessner X.kui N.kumar A.kupsc W.kühn J.J.Lane p.Larin L.Lavezzi T.T.Lei Z.H.Lei M.Lellmann T.Lenz C.Li C.Li C.H.Li Cheng Li D.M.Li F.Li G.Li H.B.Li H.J.Li H.N.Li Hui Li J.R.Li J.S.Li ke Li L.J.Li L.k.Li Lei Li M.H.Li p.R.Li Q.M.Li Q.X.Li R.Li S.X.Li T.Li W.D.Li W.G.Li X.Li X.H.Li X.L.Li X.Z.Li Xi Institute of High Energy physics Beijing 100049China Beihang University Beijing 100191China Bochum Ruhr-University D-44780BochumGermany Budker Institute of Nuclear physics SB RAS(BINp) Novosibirsk 630090Russia Carnegie Mellon University PittsburghPennsylvania 15213USA Central China Normal University Wuhan 430079China Central South University Changsha 410083China China Center of Advanced Science and Technology Beijing 100190China China University of Geosciences Wuhan 430074China Chung-Ang University Seoul06974Republic of Korea COMSATS University Islamabad Lahore CampusDefence RoadOff Raiwind Road54000LahorePakistan Fudan University Shanghai 200433China GSI Helmholtzcentre for Heavy Ion Research GmbH D-64291DarmstadtGermany Guangxi Normal University Guilin 541004China Guangxi University Nanning 530004China Hangzhou Normal University Hangzhou 310036China Hebei University Baoding 071002China Helmholtz Institute Mainz Staudinger Weg 18D-55099MainzGermany Henan Normal University Xinxiang 453007China Henan University Kaifeng 475004China Henan University of Science and Technology Luoyang 471003China Henan University of Technology Zhengzhou 450001China Huangshan College Huangshan 245000China Hunan Normal University Changsha 410081China Hunan University Changsha 410082China Indian Institute of Technology Madras Chennai 600036India Indiana University BloomingtonIndiana 47405USA INFN Laboratori Nazionali di Frascati (A)INFN Laboratori Nazionali di FrascatiI-00044FrascatiItaly(B)INFN Sezione di PerugiaI-06100PerugiaItaly(C)University of PerugiaI-06100PerugiaItaly INFN Sezione di Ferrara (A)INFN Sezione di FerraraI-44122FerraraItaly(B)University of FerraraI-44122FerraraItaly Inner Mongolia University Hohhot 010021China Institute of Modern physics Lanzhou 730000China Institute of physics and Technology Peace Avenue 54BUlaanbaatar 13330Mongolia Instituto de Alta Investigación Universidad de TarapacáCasilla 7DArica 1000000Chile Jilin University Changchun 130012China Joha

The number ofψ(3686)events collected by the BESⅢdetector during the 2021 run period is determined to be(2259.3±11.1)×10~6 by counting inclusiveψ(3686)hadronic *** uncertainty is systematic and the statistical uncertainty is ***,the numbers ofψ(3686)events collected during the 2009 and 2012run periods are updated to be(107.7±0.6)×10~6 and(345.4±2.6)×10~6,*** numbers are consistent with the previous measurements within one standard *** total number ofψ(3686)events in the three data samples is(2712.4±14.3)×10~6.

关键词： ψ(3686) inclusive process Hadronic events BESⅢdetector

predicting the outcome of closed-loop small bowel obstruction by preoperative characteristics

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World Journal of Gastrointestinal Surgery 2022年第6期14卷 556-566页

作者： Masja k Toneman Bente M de kok Frank M Zijta Stanley Oei Gijs J D van Acker Marinke Westerterp Anne E M van der pool Department of Surgery Haaglanden Medical CentreThe Hague 2512 VANetherlands Department of Radiology Haaglanden Medical CentreThe Hague 2512 VANetherlands

BACkGROUND Closed-loop small bowel obstruction(CL-SBO)can threaten the viability of the intestine by obstructing a bowel segment at two adjacent *** recognition and surgery are *** To analyze the outcomes of patients who underwent surgery for CL-SBO and to evaluate clinical *** patients who underwent surgery for suspected CL-BSO on computed tomography(CT)at a single center between 2013 and 2019 were evaluated *** were divided into three groups by perioperative outcome,including viable bowel,reversible ischemia,and irreversible *** and laboratorial variables at presentation were compared and postoperative outcomes were *** Of 148 patients with CL-SBO,28(19%)had a perioperative viable small bowel,86(58%)had reversible ischemia,and 34(23%)had irreversible *** with a higher age had higher risk for perioperative irreversible ischemia[odds ratio(OR):1.03,95%confidence interval(CI):0.99-1.06].patients with American Society of Anaesthesiologists(ASA)classification≥3 had higher risk of perioperative irreversible ischemia compared to lower ASA classifications(OR:3.76,95%CI:1.31-10.81).Eighty-six patients(58%)did not have elevated C-reactive protein(>10 mg/L),and between-group differences were *** in-hospital stay was significantly longer for patients with irreversible ischemia(median 8 d,p=0.001)than for those with reversible ischemia(median 6 d)or a viable bowel(median 5 d).postoperative morbidity was significantly higher in patients with perioperative irreversible ischemia(45%,p=0.043)compared with reversible ischemia(20%)and viable bowel(4%).CONCLUSION Older patients or those with higher ASA classification had an increased risk of irreversible ischemia in case of *** irreversible ischemia,postoperative morbidity was increased.

关键词： General surgery Laparoscopy Laparotomy Critical care Intestinal obstruction Morbidity

A study of the relation between intensity oscillations and magnetic field parameters in a sunspot: Hinode observations

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Research in Astronomy and Astrophysics 2014年第11期14卷 1458-1468页

作者： A.Raja Bayanna Shibu k.Mathew Brajesh kumar Rohan E.Louis p.Venkatakrishnan Udaipur Solar Observatory Physical Research Laboratory Leibniz-Institut für Astrophysik potsdam (AIp) An der Sternwarte 16 14482 PotsdamGermany

We present properties of intensity oscillations of a sunspot in the photo- sphere and chromosphere using G band and Ca u H filtergrams from Hinode. Intensity power maps as function of magnetic field strength and frequency reveal reduction of power in the G band with an increase in photospheric magnetic field strength at all frequencies. In Ca II H, however, stronger fields exhibit more power at high frequen- cies, particularly in the 4.5-8.0 mHz band. power distributions in different locations of the active region show that the oscillations in Ca II H exhibit more power compared to that of the G band. We also relate the power in intensity oscillations with differ- ent components of the photospheric vector magnetic field using near simultaneous spectro-polarimetric observations of the sunspot from the Hinode spectropolarime- ter. The photospheric umbral power is strongly anti-correlated with the magnetic field strength and its line-of-sight component but there is a good correlation with the trans- verse component. A reversal of this trend is observed in the chromosphere except at low frequencies （V≤ 1.5 mHz）. The power in sunspot penumbrae is anti-correlated with the magnetic field parameters at all frequencies （1.0 ≤ v ≤ 8.0 mHz） in both the photosphere and chromosphere, except that the chromospheric power shows a strong correlation in the frequency range 3-3.5 mHz.

关键词： Sun photosphere -- Sun chromosphere -- Sun oscillations -- Sun magnetic fields -- Sun Hinode

Melting of hydrous pyroxenites with alkali amphiboles in the continental mantle:*** relations and major element compositions of melts

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Geoscience Frontiers 2022年第4期13卷 48-74页

作者： Stephen F.Foley Isra S.Ezad Sieger R.van der Laan Maik pertermann School of Natural Sciences Macquarie UniversityNorth RydeNew South Wales 2109Australia Research School of Earth Sciences Australian National UniversityCanberraACT 2601Australia Tata Steel Europe Research and DevelopmentIjmuidenThe Netherlands Coos Bay OregonUSA

Melting experiments on ultramafic rocks rich in the hydrous minerals phlogopite or phlogopite+k-rich terite,some including 5%of accessory phases,have been conducted at 15 and 50 *** assemblages represent probable source components that contribute to melts in cratonic regions,but whose melt compositions are poorly known.A main series of starting compositions based on MARID xenoliths consisted of a third each of clinopyroxene(CpX),phlogopite(pHL)and k-richterite(kR)with or without 5%ilmenite,rutile or *** experiments were run without kR and with higher proportions of accessory *** traps were used at near-solidus temperatures to facilitate accurate analysis of wellquenched melts,for which reversal experiments demonstrate *** show that kR melts rapidly and completely within 50°C of the solidus,so that melts reflect the composition of the amphibole and its melting *** have high SiO_(2) and especially k_(2)O but low CaO and Al_(2)O_(3) relative to basaltic melts produced from peridotites at similar *** have no counterparts amongst natural rocks,but most closely resemble leucite lamproites at 15 *** and pHL melt incongruently to form olivine(OL)and CpX at 15 kbar,promoting SiO2 contents of the melt,whereas orthopyroxene OpX is increasingly stable at lower lithosphere pressures,leading to an increase in Mg O and decrease in SiO_(2) in melts,which resemble olivine *** of mica pyroxenites without kR are richer in CaO and Al_(2)O_(3) and do not resemble *** experiments show that low CaO and Al_(2)O_(3) in igneous rocks is not necessarily a sign of a depleted peridotite *** phases produce melts exceptionally rich in p_(2)O_(5) or TiO_(2) depending on the phases present and are unlike any melts seen at the Earth’s surface,but may be important agents of metasomatism seen in *** addition of the 5%accessory phases ilmenite,rutile or apatite result in melting temper

关键词： Hydrous pyroxenite Experimental petrology Mantle melts phlogopite Lamproite Mantle metasomatism

Environmental engineering of transition metal dichalcogenide optoelectronics

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Frontiers of physics 2018年第4期13卷 21-52页

作者： Trevor LaMountain Erik J. Lenferink Yen-Jung Chen Teodor k. Stanev Nathaniel p. Stern Department of physics and Astronomy Northwestern University Evanston Illinois 60208 USA

The explosion of interest in two-dimensional van der Waals materials has been in many ways driven by their layered geometry. This feature makes possible numerous avenues for assembling and ma- nipulating the optical and electronic properties of these materials. In the specific case of monolayer transition metal dichalcogenide semiconductors, the direct band gap combined with the flexibility for manipulation of layers has made this class of materials promising for optoelectronics. Here, we review the properties of these layered materials and the various means of engineering these properties for optoeleetronics. We summarize approaches for control that modify their structural and chemical en- vironment, and we give particular detail on the integration of these materials into engineered optical fields to control their optical characteristics. This combination of controllability from their layered surface structure and photonic environment provide an expansive landscape for novel optoelectronic phenomena.

关键词： transition metal dichalcogenides optoelectronics van der Waals materials heterostructures excitons

prediction of sediment yield of the Inxu River catchment (South Africa)using the MUSLE

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International Soil and Water Conservation Research 2021年第1期9卷 37-48页

作者： David Gwapedza Namso Nyamela Denis Arthur Hughes Andrew Robert Slaughter Sukhmani kaur Mantel Benjamin van der Waal Institute for Water Research Rhodes University P.O.Box 94GrahamstownEastern CapeSouth Africa Geography Department Rhodes University P.O.Box 94GrahamstownEastern CapeSouth Africa

The proposed site for the construction of a new dam(Laleni Dam)on the Tsitsa River in the Eastern Cape,South Africa falls within a high soil erosion zone,which is expected to affect the lifespan of the *** the sediment yield of the catchment is important from a management perspective,and thus we designed this study to assess the applicability of the Modified Universal Soil Loss Equation(MUSLE).The original MUSLE was applied to the Inxu River sub catchment,upstream of a proposed dam,over a summer rainfall period extending from October 2016 to April 2017.A modified version of the MUSLE,incorporating a storage module,was later applied over the same *** calibration of the MUSLE with and without a storage model was tested against 7 months of recorded daily suspended sediment discharge *** a storage model,we achieved a percentage bias,coefficient of efficiency and R2 of 2%,0.83 and 0.83,respectively,while without storage the performance statistics were markedly *** results suggest that a calibrated MUSLE can provide estimates of sediment yield that are valuable for regional planning,and that the inclusion of a storage component further improves the MUSLE *** the complexity of sediment generation and transport processes,a relatively simple empirical MUSLE model is a useful tool for initial sediment yield estimation for planning purposes.

关键词： MUSLE Storage component Sediment yield Erosion South Africa Inxu river

Nanostructured Graphene Surfaces promote Different Stages of Bone Cell Differentiation

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Nano-Micro Letters 2018年第3期10卷 103-114页

作者： F.F.Borghi p.A.Bean M.D.M.Evans T.van der Laan S.kumar k.Ostrikov plasma Nanoscience School of Physics The University of Sydney CSIRO Manufacturing Brazilian Centre for physics Research (CBpF) School of Chemistry Physics and Mechanical EngineeringQueensland University of Technology CSIRO-QUT Joint Sustainable processes and Devices Laboratory Commonwealth Scientific and Industrial Research Organization

Nanostructured graphene films were used as platforms for the differentiation of Saos-2 cells into bonelike cells. The films were grown using the plasma-enhanced chemical vapor deposition method, which allowed the production of both vertically and horizontally aligned carbon nanowalls(CNWs). Modifications of the techniqueallowed control of the density of the CNWs and their orientation after the transfer process. The influence of two different topographies on cell attachment, proliferation,and differentiation was investigated. First, the transferred graphene surfaces were shown to be noncytotoxic and were able to support cell adhesion and growth for over 7 ***, early cell differentiation(identified by cellular alkaline phosphatase release) was found to be enhanced on the horizontally aligned CNW surfaces, whereas mineralization(identified by cellular calcium production), a later stage of bone cell differentiation, was stimulated by the presence of the vertical CNWs on the surfaces. These results show that the graphene coatings, grown using the presented method, are biocompatible. And their topographies have an impact on cell behavior, which can be useful in tissue engineering applications.

关键词： Carbon nanowalls Graphene films Bone cell Cell differentiation plasma nanoscience