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A practical approach to imaging characteristics and standardized reporting of COVID-19:A radiologic review

Military Medical Research 2021年第3期8卷 424-432页

作者： deniz esin tekcan Sanli Duzgun Yildirim Ahmet Necati Sanli Suha Turkmen Neval Erozan Guray Husmen Aytug Altundag FilizTuzuner Department of Radiology Acibadem Kozyatagi Hospital19 Mayis Mahinonu CadOkur SokNo.24/Af Kozyatagi34734 IstanbulTurkey Department of Radiology Acibadem Taksim Hospital34373 IstanbulTurkey Cerrahpasa Medical Faculty Department of General SurgeryIstanbul University-Cerrahpasa34098 IstanbulTurkey Department of Emergency Acibadem Taksim Hospital34373 IstanbulTurkey Department of Otolaryngology Acibadem Taksim Hospital34373 IstanbulTurkey Department of Anesthesiology Acibadem Taksim Hospital34373 IstanbulTurkey

Novel coronavirus(2019-nCoV),also known as severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),is a pathogen that has caused a rapidly spreading pandemic all over the *** primary mean of transmission is inhalation with a predilection for respiratory system involvement,especially in the distal *** disease that arises from this novel coronavirus is named coronavirus disease 2019(COVID-19).COVID-19 may have a rapid and devastating course in some cases leading to severe complications and *** imaging methods have an invaluable role in diagnosis,follow-up,and *** this review,radiological imaging findings of COVID-19 have been systematically reviewed based on the published literature so *** reporting templates are also emphasized from a different point of view,considering specific distinctive patterns of involvement.

关键词： Coronavirus disease 2019 Severe acute respiratory syndrome coronavirus 2 Computed tomography Pneumonia Acute respiratory distress syndrome Ground-glass opacities Crazy-paving pattern

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Quantitative Ultrasound Elastography of Breast: A Review and Update with Emphasis on Shear Wave Imaging (ARFI)

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Open Journal of Medical Imaging 2021年第2期11卷 58-72页

作者： Duzgun Yildirim Özlem Akıncı deniz esin tekcan Department of Medical Imaging Acibadem University Vocational School of Health Sciences Istanbul Turkey Department of Radiology Sancaktepe Prof. Dr. Ilhan Varank Training and Research Hospital Istanbul Turkey Department of Radiology Acibadem University Istanbul Turkey

Elastography is a method which determines the stiffness of tissues with the help of ultrasound technology and exhibits more quantitative data according to palpation that made during physical examination. Elastography has relatively entered to routine use in the breast evaluation with imaging techniques. Although palpation has a very long history, elastography has been used since 1990s. Elastography is used as an adjunct to conventional gray scale ultrasound and can identify the stiffness of the tissues non-invasively. Today, it is used as two separate technological modalities: strain elastography and shear wave elastography. The aims of these modalities are to increase the sensitivity of the separation between malignant and benign lesions, reduce the unnecessary biopsy processes and to provide a more accurate Breast Imaging Reporting and Data System (BIRADS) categorization of the breast lesions. In this article, we aimed to review the clinical utilization and benefits of elastography in differantial diagnosis of breast lesions, BIRADS categorization, and biopsy decision making in the light of current literature.

关键词： Breast Elastography Shear Wave Elastography Ultrasound

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Hashimoto Thyroiditis:Simple Diagnosis with 2D-Shear Wave Elastography

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International Journal of Clinical Medicine 2020年第2期11卷 23-31页

作者： Düzgün Yildirim deniz esin tekcan Sanli deniz Alis Mutlu Sahin Alev Bakir Ahmet Erdem Kilavuz Department of Medical Imaging Vocational School of Health SciencesAcibadem UniversityIstanbulTurkey Department of Radiology Acibadem Kozyatagi HospitalIstanbulTurkey Department of Radiology Istanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Research and Training HospitalIstanbulTurkey Department of General Surgery Diskapi Yildirim Beyazit Education and Research HospitalAnkaraTurkey Biostatistics and Medical Informatics Department Halic UniversityIstanbulTurkey Department of Otorhinolaryngology Acibadem UniversityIstanbulTurkey

Background: Hashimoto thyroiditis diagnosis is primarily established on clinical and laboratory findings;however, some hashimoto thyroiditis cases are euthyroid and seronegative. Moreover, these patients might also have normal conventional ultrasound findings. Aims: In our study, we aimed to distinguish the typical background characteristics of hashimoto thyroiditis using virtual touch tissue imaging quantification maps obtained with acoustic radiation force impulse imaging. Methods: Our study consisted of 28 hashimoto thyroiditis patients without characteristics of ultrasound findings and 28 healthy subjects. The thyroid parenchymal tissue mechanical properties were analyzed with the virtual touch tissue imaging quantification after ultrasound examination, and then related colored maps were obtained. Shear wave velocities were recorded (m/s) from the homogenous area where hardest and softest points were closest to each other on virtual touch tissue imaging quantification maps. The difference between the minimum and maximum shear wave velocities for each case (Δv) was calculated and recorded. Results: Assessment of virtual touch tissue imaging quantification maps revealed a significant difference between hashimoto thyroiditis and control groups in terms of maximum SWV’s, but no significant difference was observed between the minimum shear wave velocities (p Δv values were taken into account. In summary, the effects of chronic autoimmune thyroiditis can be distinguished by simply using Δv on virtual touch tissue imaging quantification maps. When the cut-off value of Δv was accepted 0.42, the diagnosis of hashimoto thyroiditis could be made with 88% accuracy. Conclusion: We suggest that shear wave velocities measurement on virtual touch tissue imaging quantification maps is a promising method in equivocal hashimoto thyroiditis cases, in which the diagnosis of hashimoto thyroiditis is unachievable with clinical, laboratory and conventional ultra

关键词： ARFI Hashimoto Thyroiditis SWE SWV VTIQ

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Asian Journal of Andrology 2013年第2期15卷 269-274,I0009页

作者： Orcun Celik Omer Kutlu Merih tekcan CUer Celik-Ozenci Ismail T Koksal Department of Urology Faculty of Medicine Akdeniz University Antalya 07070 Turkey Department of Urology Faculty of Medicine Karadeniz Technical University Trabzon 61080 Turkey Department of Histology and Embryology Faculty of Medicine Akdeniz University Antatya 07070 Turkey

The higher frequency of varicocele in men with infertility has drawn attention and resulted in increased research at the molecular level towards treatments. The aim of this study was to investigate the role of tumor necrosis factor （TNF）-related apoptosis-inducing ligand （TRAIL） and its receptors in varicocele-induced testicular dysfunction in an experimental rat model. The rats were divided into three groups： control, sham and varicocele. Varicoceles in rats were induced by partial ligation of the left renal vein and left testes. The rats were analyzed 13 weeks after surgery. The degree of DNA fragmentation within cells in the testis was determined using terminal deoxynucleotidyl transferase deoxyuridine triphosphate nick end labeling （TUNEL） assay. Tubule degeneration was evaluated using the Johnsen score. The expression of TRAIL and its receptors was detected by immunohistochemical and Western blotting techniques. The apoptotic index, Johnsen score and the expression of TRAIL and TRAIL receptors were examined. The data are presented as the mean-.＋s.d, and were analyzed using computer software. The KruskaI-Wallis and Dunn＇s multiple comparison tests were used in the statistical analyses. The germ cell apoptotic index was increased in rats with varicoceles when compared with the sham and control groups （P=0.0031）. The Johnsen score was significantly decreased in the varicocele group when compared with the sham and control groups （P〈O.O001）. Immunohistochemical and Western blotting analyses showed that after varicocele induction, the expression of TRAIL-R1 and TRAIL-R4 in germ cells was increased and the expression of TRAIL-R2 was decreased. There are no significant differences among the groups in terms of TRAIL and TRAIL-R3 receptor expression. The results of this study indicate that TRAIL and its receptors may have a potential role in the pathogenesis of varicocele-induced testicular dysfunction.

关键词： apoptosis infertility testis TNF-related apoptosis inducing ligand (TRAIL) varicocele

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