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社会支持理论视域下中国式现代化体育发展的现实之困与纾解之策

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天津体育学院学报 2024年第1期39卷 64-70页

作者：李彦龙陈德明常凤肖平哈尔滨体育学院学术理论研究部黑龙江哈尔滨150008 哈尔滨体育学院校长办公室黑龙江哈尔滨150008 哈尔滨体育学院运动人体科学学院黑龙江哈尔滨150008 湖北大学体育学院湖北武汉430062

中国式现代化体育是为满足全体人民体育需要,从传统体育向现代体育发展转向的具有中国特色的社会主义体育现代化。现代化已成为我国体育事业发展新诉求、新目标、新征程,加快推进中国式现代化体育发展是促进中国式现代化的必然选择。运... 详细信息

中国式现代化体育是为满足全体人民体育需要,从传统体育向现代体育发展转向的具有中国特色的社会主义体育现代化。现代化已成为我国体育事业发展新诉求、新目标、新征程,加快推进中国式现代化体育发展是促进中国式现代化的必然选择。运用文献资料法与逻辑分析法,基于社会支持系统四要素“主体—客体—内容—手段”为逻辑主线,分析中国式现代化体育发展的现实困境。研究认为:主体供给乏力制约中国式现代化体育支持网络的形成,客体动力不足制约中国式现代化体育的普遍参与,支持内容贫乏阻滞中国式现代化体育的全面发展,支持手段有限阻碍中国式现代化体育的社会联结。实现多元主体支持,为中国式现代化体育供给提供有效保障;提升客体参与动力,为中国式现代化体育参与提供内生动力;丰富内容体系构建,为中国式现代化体育发展创造良好条件;改善社会支持手段,为中国式现代化体育发展提供关键支撑等纾解策略。

关键词：中国式现代化体育强国社会支持

Gene expression disparity in giant cell tumor of bone

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Frontiers of Medicine 2009年第1期3卷 49-56页

作者： xiaohua PAN Shuhua YANG deming xiao Yong DAI Lili REN Department of Orthopaedics Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Department of Orthopaedics Shenzhen People’s HospitalThe Second Medical College of Jinan UniversityShenzhen 518020China Clinical Research Center Shenzhen People’s HospitalThe Second Hospital Medical College of Jinan UniversityShenzhen 518020China

The aim of this paper was to study the differential gene expression of giant cell tumor of bone(GCTB)by gene chip technology.Total RNA of 8 fresh GCTB specimens(Jaffe I∶6 cases,II∶1 case,III∶1 case;Campanacci I∶6 cases,II∶1 case,III∶1 case;Enneking Staging G0T1-2M0,5 cases,G1T1-2M0:2 cases,G1T2M0:1 case)and 4 normal bony callus specimens(the control group)were extracted and puriﬁed to get mRNA and then reverse transcribed to complementary DNA,respectively.Microarray screening with a set of 8064 human cDNA genes was conducted to analyze the difference among the samples and the control.The hybridization signals were scanned.The gene expression disparity between the GCTB samples and normal bony callus was signiﬁcantly different(P<0.01),and the disparity of over 5-fold was found in 47 genes in the GCTB specimens,with 25 genes up-regulated and 22 down-regulated including the extracellular matrix and transforming-related genes,oncogene and its homolog genes,cytokine and its receptor genes.Speciﬁc gene spectrum associated with GCTB can be identiﬁed by cDNA microarray,which will be the foundation of progressive etiology elucidation,diagnosis and treatment of GCTB.

关键词： giant cell tumor of bone gene microarray,cDNA

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家具用抽屉导轨的国内外标准比对

家具 2024年第1期45卷 112-116,126页

作者：肖俊华赵斌赖德明王红强关鹏飞广东产品质量监督检验研究院广州510670 国家家具产品质量检验检测中心顺德528300

为探究国内外家具用抽屉导轨的技术和标准水平差异,对国内标准与欧美标准的技术指标进行比对分析,结果表明:国内现行行业标准除强度要求稍低外,耐久性、拉出安全性和耐腐蚀性能均严于欧洲标准;团体标准在特色项目和绿色低碳生产上更具优... 详细信息

为探究国内外家具用抽屉导轨的技术和标准水平差异,对国内标准与欧美标准的技术指标进行比对分析,结果表明:国内现行行业标准除强度要求稍低外,耐久性、拉出安全性和耐腐蚀性能均严于欧洲标准;团体标准在特色项目和绿色低碳生产上更具优势;美国标准技术要求整体上低于中国标准和欧洲标准。研究结果可为我国家具用抽屉导轨的标准制修订、相关企业生产贸易等提供参考。

关键词：抽屉导轨标准比对标准制修订

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成品尿素包装破损污染的原因分析及处理

大氮肥 2024年第2期47卷 136-137,140页

作者：邓光炯白文杰白文宾肖德明李欣杰中国石油宁夏石化公司宁夏银川750026

结合尿素产品储运情况,详细分析影响成品尿素外观质量的因素,通过改进作业模式、维护保养和优化管理等措施,消除影响成品尿素外观质量的因素,提升尿素质量,保证企业品牌的质量效益。

关键词：成品尿素破袋污染外观质量

Identification of circulating miRNA biomarkers based on global quantitative real-time PCR profiling

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Journal of Animal Science and Biotechnology 2012年第2期3卷 51-59页

作者： Kang Kang xiao Peng Jun Luo deming Gou College of Life Science Shenzhen UniversityShenzhenGuangdong518060China College of Animal Science and Technology Northwest A&F UniversityYanglingShaanxi712100China

MicroRNAs （miRNAs） are small noncoding RNAs （18-25 nucleotides） that regulate gene expression at the posttranscriptional level. Recent studies have demonstrated the presence of miRNAs in the blood circulation. Deregulation of miRNAs i n serum or plasma has been associated with many diseases including cancers and cardiovascular diseases, suggesting the possible use of miRNAs as diagnostic biomarkers. However, the detection of the small amount of miRNAs found in serum or plasma requires a method with high sensitivity and accuracy. Therefore, the current study describes polymerase chain reaction （PCR）-based methods for measuring circulating miRNAs. Briefly, the procedure involves four major steps：（1） sample collection and preparation; （2） global miRNAs profiling using quantitative real-time PCR （qRT-PCR）; （3） data normalization and analysis; and （4） selection and validation of miRNA biomarkers. In conclusion, qRT-PCR is a promising method for profiling of circulating miRNAs as biomarkers.

关键词： biomarker circulating microRNAs profiling quantitative real-time PCR

EACS: An Efficient Access Control Scheme for Electronic Publishing in Cloud Computing

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Chinese Journal of Electronics 2018年第1期27卷 60-69页

作者： WU deming ZHANG Yu WANG Lina HOU Jian xiao Lei CHEN Wei ZHOU Qing School of Computer Wuhan University Science and Technology on Information Assurance Laboratory Army Aviation Research Institute Air Force Engineering University 95942 troops 24 squad

To guarantee that electronic publications are accessible only to the authorized users via cloud, we propose an Efficient access control scheme(EACS) based on Attribute-based encryption(ABE), which is suitable for fine-grained access control. Compared with existing stateof-the-art schemes, EACS is more practical by following functions. Considering the factor that the user membership may change frequently, EACS has the capability of coping with dynamic membership efficiently. Arbitrary-State is also supported to facilitate the system management and improve efficiency. Besides, we prove in the standard model that the security of EACS is based on the Decisional Bilinear Diffie-Hellman assumption. To evaluate the practicality of EACS, we provide a detailed theoretical performance analysis and a simulation comparison with existing schemes. Both the theoretical analysis and the experimental results show that our proposal is efficient and practical for electronic publishing under cloud environment.

关键词： Electronic publishing Attribute-based encryption Cloud computing Access control Dynamic membership Arbitrary-state

Efficiently Writing Bragg Grating in High-Birefringence Elliptical Microfiber for Label-Free Immunosensing with Temperature Compensation

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Advanced Fiber Materials 2021年第5期3卷 321-330页

作者： Peng xiao Zhiyuan Xu deming Hu Lili Liang Lipeng Sun Jie Li Yang Ran Bai‑Ou Guan Guangdong Provincial Key Laboratory of Optical Fiber Sensing and Communications Institute of Photonics TechnologyJinan UniversityGuangzhou 510632China Ji Hua Laboratory Foshan 528300China Institute of Information Technology Handan UniversityHandan 056005China

Immunosensor is a powerful tool in healthcare and clinic,food and drug industry,and environmental protection.Label-free fiber-optic immunosensors have shown a myriad of advantages,such as high sensitivity,anti-electromagnetic interference,and afield measurement via the fiber network.However,the fiber-optic based sensor may bear the temperature cross-talk,especially under the warming condition for bio-activating the immune molecules.In this study,we proposed a highly birefringent microfiber Bragg grating for immunosensing with the temperature-compensation.The birefringent microfiber was drawn from the elliptical cladding multimode fiber that was ablated by the CO2 laser.The considerably large energy overlap region offered by the original multimode fiber favored the efficient inscription of FBG with high reflectivity.The dual reso-nances derived by the orthogonal polarization states presented similar temperature responsivities but significantly different ambient refractive index sensitivities,allowing the temperature-compensational RI sensing.The human immunoglobulin G(IgG)molecules were anchored on the surface of the microfiber grating probe by the covalent functionalization technique to enable the specific detection of the anti-IgG molecule.The proposed method promises a high-efficiency and low-cost design for the microfiber Bragg grating-based biosensor without being subjected to the temperature cross-sensitivity.

关键词： Fiber-optic biosensors Microfiber Fiber Bragg grating Birefringence Temperature compensation Immunosensing

透明质酸微针经皮递送胰岛素智能给药系统用于糖尿病治疗

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生物工程学报 2022年第9期38卷 3433-3442页

作者：肖永成王小斌谢德明暨南大学生物医学工程系广东广州510630 广州质量监督检测研究院广东广州511447

本研究通过共沉淀法制备了胰岛素(insulin,INS)/Ca_(3)PO_(4)复合物和葡萄糖氧化酶(glucose oxidase,GOx)/Cu_(3)(PO_(4))_(2)复合物,得到的矿化胰岛素(mineralized insulin,m-INS)呈现不规则结晶团簇状,矿化葡萄糖氧化酶(m-Gox)呈花球状形貌,直径约1–2μm。体外模拟释放实验表明,m-INS会随介质pH值降低而释放出INS,pH为4.5时其释放量达到96.68%;酶活力检测实验表明m-GOx的酶活力稳定性高于游离的GOx,在室温放置10 d后仍保持较高活力,而GOx活力小于60%。通过配制葡萄糖溶液模拟正常血糖(5.6 mmol/L)和高血糖(22.2 mmol/L)状态,在葡萄糖溶液中加入m-INS和m-GOx,INS的释放量呈现显著的葡萄糖浓度依赖性,即葡萄糖浓度越高,INS释放量和释放速率越大。最后,将m-INS、m-GOx与透明质酸(hyaluronic acid,HA)溶液混合,制备负载m-INS和m-GOx的HA微针阵列,构建1型糖尿病模型鼠,通过微针给药的方式评估载药HA微针对糖尿病大鼠的血糖控制效果。结果表明:负载m-INS/m-GOx的HA微针能有效递送药物,糖尿病大鼠的平均血糖浓度在1 h内下降到约7 mmol/L,并能维持10 h的正常血糖,使血糖浓度低于给药前水平长达36 h。与仅负载INS的HA微针相比,m-INS微针具有更好的葡萄糖耐受性、更持久的控糖效果和更小的低血糖风险。相对于其他的缓释系统,本研究中的核心成分制备流程简单、效率高和安全有效,具备较大的商业化潜力。

关键词：透明质酸微针透皮给药糖尿病治疗胰岛素智能释放

A rapid-prototyped composite scaffold material incorporating an osteopromotive molecule can promote the healing of steroid-associated osteonecrotic lesion in emus.

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A rapid-prototyped composite scaffold material incorporating...