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EEG Emotion Recognition Using an Attention Mechanism Based on an Optimized Hybrid Model

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Computers, Materials & Continua 2022年第11期73卷 2697-2712页

作者： Huiping Jiang demeng wu Xingqun Tang Zhongjie Li Wenbo wu Brain Cognitive Computing Lab School of Information EngineeringMinzu University of ChinaBeijing100081China Case Western Reserve University USA

Emotions serve various *** traditional emotion recognition methods are based primarily on readily accessible facial expressions,gestures,and voice ***,it is often challenging to ensure that these non-physical signals are valid and reliable in practical ***(EEG)signals are more successful than other signal recognition methods in recognizing these characteristics in real-time since they are difficult to *** EEG signals are commonly used in current emotional recognition research,the accuracy is low when using traditional ***,this study presented an optimized hybrid pattern with an attention mechanism(FFT_CLA)for EEG emotional ***,the EEG signal was processed via the fast fourier transform(FFT),after which the convolutional neural network(CNN),long short-term memory(LSTM),and CNN-LSTM-attention(CLA)methods were used to extract and classify the EEG ***,the experiments compared and analyzed the recognition results obtained via three DEAP dataset models,namely FFT_CNN,FFT_LSTM,and FFT_*** final experimental results indicated that the recognition rates of the FFT_CNN,FFT_LSTM,and FFT_CLA models within the DEAP dataset were 87.39%,88.30%,and 92.38%,*** FFT_CLA model improved the accuracy of EEG emotion recognition and used the attention mechanism to address the often-ignored importance of different channels and samples when extracting EEG features.

关键词： Emotion recognition EEG signal optimized hybrid model attention mechanism

Emotion Analysis: Bimodal Fusion of Facial Expressions and EEG

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Computers, Materials & Continua 2021年第8期68卷 2315-2327页

作者： Huiping Jiang Rui Jiao demeng wu Wenbo wu Brain Cognitive Computing Lab School of Information EngineeringMinzu University of ChinaBeijing100081China Case Western Reserve University USA

With the rapid development of deep learning and artificial intelligence,affective computing,as a branch field,has attracted increasing research *** emotions are diverse and are directly expressed via nonphysiological indicators,such as electroencephalogram(EEG)***,whether emotion-based or EEG-based,these remain single-modes of emotion ***-mode fusion emotion recognition can improve accuracy by utilizing feature diversity and ***,three different models have been established:the single-mode-based EEG-long and short-term memory(LSTM)model,the Facial-LSTM model based on facial expressions processing EEG data,and the multi-mode LSTM-convolutional neural network(CNN)model that combines expressions and *** average classification accuracy was 86.48%,89.42%,and 93.13%,*** with the EEG-LSTM model,the Facial-LSTM model improved by about 3%.This indicated that the expression mode helped eliminate EEG signals that contained few or no emotional features,enhancing emotion recognition *** with the Facial-LSTM model,the classification accuracy of the LSTM-CNN model improved by 3.7%,showing that the addition of facial expressions affected the EEG features to a certain ***,using various modal features for emotion recognition conforms to human emotional ***,it improves feature diversity to facilitate further emotion recognition research.

关键词： Single-mode and multi-mode expressions and EEG deep learning LSTM

乡村振兴战略背景下贵州省新型城镇化发展路径

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科技和产业 2024年第7期24卷 64-69页

作者：伍达富王琴母欢欢潘德猛黔南民族职业技术学院贵州都匀558022

贵州省新型城镇化的发展能够推动地区经济,也是实现乡村振兴战略的重要路径。贵州省城镇化建设过程中存在着城乡之间差距大、城乡公共基础设施配置不均等问题。通过研究贵州省城镇化发展现状,指出贵州省新型城镇化发展过程存在的问题,... 详细信息

贵州省新型城镇化的发展能够推动地区经济,也是实现乡村振兴战略的重要路径。贵州省城镇化建设过程中存在着城乡之间差距大、城乡公共基础设施配置不均等问题。通过研究贵州省城镇化发展现状,指出贵州省新型城镇化发展过程存在的问题,从完善城乡空间布局、挖掘乡村资源、加强生态环境保护、完善政策制度体系、探索创新模式5个方面,提出贵州省新型城镇化发展路径。

关键词：贵州省新型城镇化乡村振兴发展路径

The putative propeptide of MycP1 in mycobacterial type VII secretion system does not inhibit protease activity but improves protein stability

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Protein & Cell 2013年第12期4卷 921-931页

作者： demeng Sun Qing Liu Yao He Chengliang Wang Fangming wu Changlin Tian Jianye Zang National Laboratory for Physical Science at the Microscale and School of Life Sciences University of Science and Technology of ChinaHefei 230026China High Magnetic Field Laboratory Chinese Academy of SciencesHefei 230031China

Mycosin-1 protease(MycP1)is a serine protease anchored to the inner membrane of Mycobacterium tuberculosis,and is essential in virulence factor secretion through the ESX-1 type VII secretion system(T7SS).Bacterial physiology studies demonstrated that MycP1 plays a dual role in the regulation of ESX-1 secretion and virulence,primarily through cleavage of its secretion substrate ***1 contains a putative N-terminal inhibitory propeptide and a catalytic triad of Asp-His-Ser,classic hallmarks of a sub-tilase family serine *** MycP1 propeptide was previously reported to be initially inactive and activated after prolonged *** this study,we have deter-mined crystal structures of MycP1 with(MycP124-422)and without(MycP1^(63-422))the propeptide,and conducted EspB cleavage assays using the two *** high struc-tural similarity was observed in the two crystal ***,protease assays demonstrated positive EspB cleavage for both proteins,indicating that the putative propeptide does not inhibit protease ***-lar dynamic simulations showed higher rigidity in regions guarding the entrance to the catalytic site in MycP124-422 than in MycP1^(63-422),suggesting that the putative propeptide might contribute to the conformational stability of the active site cleft and surrounding regions.

关键词： type VII ESX-1 secretion system serine protease propeptide crystal structure EspB cleavage molecular dynamic simulations

Isocitrate dehydrogenase(IDH) mutations in Cancers

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Isocitrate dehydrogenase(IDH) mutations in Cancers

Chemical Synthesis of Structurally Defined Phosphorylated Ubiquitins Suggests Impaired Parkin Activation by Phosphorylated Ubiquitins with a Non-Phosphorylated Distal Unit

中国生物化学与分子生物学会2016年全国学术会议

作者： Peipei Yang demeng Peng Xiaolan Liu Yeqing wu Wen-Bin Ou Zhejiang Provincial Key Laboratory of Silkworm Bioreactor and Biomedicine College of Life Sciences Zhejiang Sci-Tech University Zhejiang Provincial Key Laboratory of Applied Enzymology Yangtze Delta Region Institute of Tsinghua University

Isocitrate dehydrogenase(IDH)is a kind of crucial enzyme family in tricarboxylic acid(TCA)cycle,which convents socitric acid toα-ketoglutarate(α-KG)in *** clinical data have shown that the point mutations in the activesite arginine residues of IDH(IDH1/R132,IDH2/R140,and IDH2/R172)occur frequently in a variety of cancers,including

关键词： IDH mutation cancers

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CCS Chemistry 2019年第5期1卷 476-489页

作者： Man Pan Qingyun Zheng Shuai Gao Qian Qu Yuanyuan Yu Ming wu Huan Lan Yulei Li Sanling Liu Jiabin Li demeng Sun Lining Lu Tian Wang Wenhao Zhang Jiawei Wang Yiming Li Hong-Gang Hu Changlin Tian Lei Liu Tsinghua-Peking Center for Life Sciences Ministry of Education Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical BiologyCenter for Synthetic and Systems BiologyState Key Laboratory of Chemical OncogenomicsDepartment of ChemistryTsinghua UniversityBeijing 100084China State Key Laboratory of Chemical Oncogenomics Key Laboratory of Chemical BiologyGraduate School at ShenzhenTsinghua UniversityShenzhenGuangdong 518055China Institute of Translational Medicine Shanghai UniversityShanghai 200444China Hefei National Laboratory for Physical Sciences at Microscale and School of Life Sciences University of Science and Technology of ChinaHefei 230027China School of Biological and Medical Engineering Hefei University of TechnologyHefeiAnhui 230009China

Mutations in genes encoding PINK1(PTEN-induced kinase 1)and Parkin(E3 ubiquitin ligase)are identified in familial Parkinson’s ***,it remains unclear whether the phosphorylated Ub chains activate wild-type Parkin(w-Pa... 详细信息

关键词： chemical protein synthesis ubiquitin phosphorylation Parkin mitochondrial autophagy

混合稀土变质对A390合金显微组织及力学性能的影响

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铸造技术 2024年第5期45卷 487-493页

作者：王亚东王建华奎永才雷强吴华洋李薇隋育栋云南德孟高速公路投资开发有限公司云南保山678013 云南省交通规划设计研究院股份有限公司云南昆明650041 昆明理工大学材料科学与工程学院云南昆明650500

铝硅合金拥有良好的成型性和较高的力学性能,被广泛应用于各个行业。但过共晶铝硅合金铸态组织中存在的粗大不规则块状初晶硅相会割裂基体,显著降低合金力学性能。本文采用OM、SEM及万能材料试验机等研究混合稀土La、Ce变质A390过共晶... 详细信息

铝硅合金拥有良好的成型性和较高的力学性能,被广泛应用于各个行业。但过共晶铝硅合金铸态组织中存在的粗大不规则块状初晶硅相会割裂基体,显著降低合金力学性能。本文采用OM、SEM及万能材料试验机等研究混合稀土La、Ce变质A390过共晶铝硅合金的微观组织和力学性能。结果表明,混合稀土对初晶硅的变质效果明显,随着混合稀土含量的增加,初晶硅的体积分数和合金的力学性能呈先增加后降低的趋势,当混合稀土加入量为0.58%(其中La为0.33%,Ce为0.25%,质量分数)时,初晶硅的体积分数达到最小值9.37%,铸态合金的抗拉强度和伸长率分别为229 MPa和1.7%。

关键词： A390合金混合稀土初晶硅共晶硅力学性能

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蓝莓对大鼠肝星状细胞T6凋亡及Bcl-2、Bax表达的影响

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中华医学杂志 2015年第31期95卷 2560-2564页

作者：陆爽程明亮杨德猛刘洋关丽吴君贵阳医学院感染病学教研室 550004

目的探讨蓝莓对大鼠肝星状细胞（HSC-T6）凋亡及Bcl-2和Bax表达的影响.方法血清药理学方法制备大鼠10％蓝莓低、中、高剂量血清、复方鳖甲软肝片血清及生理盐水血清.传代培养的HSC-T6分为生理盐水血清组、蓝莓低剂量血清组、蓝莓中剂... 详细信息

目的探讨蓝莓对大鼠肝星状细胞（HSC-T6）凋亡及Bcl-2和Bax表达的影响.方法血清药理学方法制备大鼠10％蓝莓低、中、高剂量血清、复方鳖甲软肝片血清及生理盐水血清.传代培养的HSC-T6分为生理盐水血清组、蓝莓低剂量血清组、蓝莓中剂量血清组、蓝莓高剂量血清组及复方鳖甲软肝片血清组,将上述血清分别加入各组HSC-T6,培养72 h后采用Annexin V/PI检测各组HSC-T6的凋亡,Western印迹及免疫细胞化学检测各组HSC-T6 Bax及Bcl-2蛋白的表达.结果与生理盐水血清组比较,蓝莓低、中、高剂量血清组HSC-T6 Bax蛋白表达差异无统计学意义;蓝莓高剂量血清组HSC-T6早期及总凋亡率明显高于生理盐水血清组（5.55％±0.98％比2.53％±0.46％,7.01％±1.05％比2.96％±0.81％,均P＜0.05）;Bcl-2蛋白表达明显低于生理盐水血清组（A值,82±35比51±13,P＜0.05）;Bcl-2/Bax比值明显低于生理盐水血清组（0.26±0.02比0.46±0.03,P＜0.05）;蓝莓低、中剂量血清组HSC-T6早期及总凋亡率、Bcl-2的表达及Bcl-2/Bax的比值与生理盐水血清组比较差异均无统计学意义.结论蓝莓可通过下调Bcl-2、降低Bcl-2/Bax的比值诱导HSC-T6的凋亡,从而对大鼠肝纤维化有潜在的干预作用.

关键词：细胞凋亡肝硬化蓝莓肝细胞

针灸对多发性骨髓瘤患者化疗相关周围神经病变的干预效果

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实用临床医药杂志 2022年第2期26卷 28-30页

作者：王磊徐晓度姚利娟黄雨婷邹璆吴冰殷德猛南京中医药大学附属苏州市中医医院血液科江苏苏州215009 南京中医药大学附属苏州市中医医院肿瘤外科江苏苏州215009

目的探讨针灸对化疗相关周围神经病变(CIPN)的多发性骨髓瘤(MM)患者生活质量及预后的影响。方法将符合入选标准的54例MM患者随机分为药物组28例和针灸组26例。采用肌电图(EMG)记录神经传导速度(NCV),评估治疗效果。分别记录2组患者治疗... 详细信息

目的探讨针灸对化疗相关周围神经病变(CIPN)的多发性骨髓瘤(MM)患者生活质量及预后的影响。方法将符合入选标准的54例MM患者随机分为药物组28例和针灸组26例。采用肌电图(EMG)记录神经传导速度(NCV),评估治疗效果。分别记录2组患者治疗前后运动神经传导速度(MNCV)、感觉神经传导速度(SNCV)及癌症治疗功能评价系统/妇科肿瘤组-神经毒性评价工具量表(FACT/GOG-Ntx)评分。结果2组治疗后的正中神经和腓总神经MNCV与治疗前比较,差异有统计学意义(P0.05);2组治疗后FACT/GOG-Ntx量表评分比较,差异无统计学意义(P>0.05)。结论针灸是多发性骨髓瘤CIPN的有效干预手段之一,可提高患者的生活质量。

关键词：针灸化疗周围神经病变多发性骨髓瘤神经传导速度