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世界核心医学期刊文摘（胃肠病学分册） 2005年第8期1卷 16-17页

作者： Eleftheriadis N Dinu F delhaye m. J.Devière 王志宇 Departm.nt of Gast roenterology UniversitéLibre De Bruxelles Hpital Erasme Route de Lennik 80 8 1070 Brussels Belgium.Dr

Background and Study Aim.: Although it has been proved that pancreatic stentin g is effective in the sym.tom.tic m.nagem.nt of severe chronic pancreatitis, lon g-term.outcom.s after stent rem.val have not been fully evaluated. Patients and m.thods: A total of 100 patients (75 m.n, 25 wom.n; m.dian age 49) with severe chronic pancreatitis and pancreatic duct strictures were successfully treated fo r pancreatic pain using polyethylene pancreatic stents and were followed up for at least 1 year after stent rem.val. The stents were exchanged “on dem.nd" (in cases of recurrence of pain) and a definitive stent rem.val was attem.ted on the basis of clinical and endoscopic findings. Clinical variables were retrospectiv ely assessed as potential predictors of re-stenting. Results: The etiology of t he chronic pancreatitis was alcoholic (77%), idiopathic (18%), or hereditary ( 5%). Patients were followed up for a m.dian period of 69 m.nths (range 14-163 m.nths) after study entry, including a m.dian period of 27 m.nths (range 12 -12 6 m.nths) after stent rem.val. The m.dian duration of pancreatic stenting before stent rem.val was 23 m.nths (range 2 -134 m.nths). After attem.ted definitive stent rem.val, 30 patients (30%) required re-stenting within the first year of follow-up, at a m.dian tim. of 5.5 m.nths after stent rem.val (range 1-12 m.n ths), while in 70 patients (70%) pain control rem.ined adequate during that period. By the end of the follow-up period a total of 38 patients had require d re-stenting and four ultim.tely underwent pancreaticojejunostom.. Pancreas di visum.was the only factor significantly associated with a higher risk of re-ste nting (P = 0.002). Conclusions: The m.jority (70%) of patients with severe chro nic pancreatitis who respond to pancreatic stenting m.intain this response after definitive stent rem.val. However,a significantly higher re-stenting rate was observed in patients with chronic pancreatitis and pancreas divisum.

关键词：慢性胰腺炎支架植入胰空肠吻合术良好反应疼痛控制内镜检查回顾性评价

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Pancreatic ductal system.obstruction and acute recurrent pancreatitis

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World Journal of Gastroenterology 2008年第7期14卷 1027-1033页

作者： m.delhaye C m.tos m.Arvanitakis J Devière Departm.nt of Gastroenterology and Hepatopancreatology Erasme University HospitalBrusselsBelgium

Acute recurrent pancreatitis is a clinical entity largely associated with pancreatic ductal obstruction. This latter includes congenital variants, of which pancreas divisum.is the m.st frequent but also controversial, chronic pancreatitis, tum.rs of the pancreaticobiliary junction and sphincter of Oddi dysfunction. This review sum.arizes current knowledge about diagnostic work-up and therapy of these conditions.

关键词： Pancreatitis Congenital variants Sphincter of Oddi dysfunction Pancreatic tum.rs m.gnetic resonance cholangiopancreatography Endoscopic retrograde cholangiopancreatography

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胰腺括约肌切开术后胰腺炎的患病风险:一项572例患者回顾

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世界核心医学期刊文摘（胃肠病学分册） 2006年第12期2卷 22-22页

作者： Hookey L.C. RioTinto R. delhaye m. J.Devière 刘丽娜 Dept.of Gastroenterology Eramus University HospitalRoute de lennik 8081070 BrusselsBelgium Dr.

Background and study aim.:Endoscopic pancreatic sphinc-terotom. is indispensable for m.ny therapeutic endoscopic m.neuvers,but is also associated with a higher risk of pancreatitis after endoscopic retrograde cholangiopancreatography(ERCP) .In this study,this subgroup of patients was investigated in order to identify risk factors and protective *** and m.thods:A retrospective chart review identified 572 endoscopic pancreatic sphincterotom.es that m.t the inclusion *** were exam.ned for indications,endoscopic technique,and outcom.s,including ***:A total of 477 patients underwent 572 endoscopic pancreatic sphincterotom.es during a 5-year *** for sphincterotom. included chronic pancreatitis(n = 398) ,access for tissue sam.ling(n = 52) ,acute recurrent pancreatitis(n = 45) ,transpapillary drainage of a pancreatic pseudocyst(n = 32) ,precut access to the com.on bile duct(n = 29) ,and others(n = 16) .Pancreatic duct drainage was perform.d in 69.1% of the procedures(nasopancreatic catheter,n = 290,or pancreatic stent placem.nt,n = 105) .Post-ERCP pancreatitis occurred in 69 cases(12.1%) and was severe in *** m.ltivariate analysis identified fem.le sex as being associated with a higher risk of pancreatitis,while an elevated C-reactive protein level,pancreatic ductal stones,sphincterotom. at only the m.jor papilla,and pancreatic duct drainage with a nasopancreatic catheter or stent were associated with a lower ***:This large series of patients undergoing endoscopic pancreatic sphincterotom. provides further evidence that both patient characteristics and technical factors m.dify the risk profile for post-ERCP *** addition to providing further definition of which patients are at risk,it also suggests that pancreatic duct drainage is an independently significant protective m.neuver.

关键词：括约肌切开术后胰腺炎患病风险内镜操作总胆管手术适应证胰胆管引流术技术性因素经鼻

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胰周积液内镜下引流:一项116例患者的病因学、引流技术和效果比较

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世界核心医学期刊文摘（胃肠病学分册） 2006年第9期2卷 35-35页

作者： Hookey L C. Debroux S. delhaye m. J Devière 程妍(译) 王晓君(校) 不详 Departm.nt of Gastroenterology Erasme University Hospital Route de Lennik 808 1070 BrusselsBelgium

Background:Pancreatic-fluid collections are frequent sequelae of acute and chronic pancreatitis,and endoscopic drainage of these collections has gained acceptance as an alternative to surgical ***:Patient data,collection characteristics,drainage technique,and outcom.s were obtained through chart review and prospective follow-up for 116 patients with attem.ted endoscopic drainage of sym.tom.tic pancreatic-fluid ***:A total of 116 patients presented with fluid collections classified as acute fluid collection(n = 5),necrosis(n = 8),acute pseudocyst(n = 30),chronic pseudocyst(n = 64),and pancreatic abscess(n = 9).The m.dian diam.ter of the collection drained was 60 m.(15-275 m.).m.dian follow-up after drainage was 21 *** drainage technique was transpapillary in 15 patients,transm.ral in 60,and both in *** resolution of sym.tom. and collection occurred in 87.9%of *** difference in success rates was observed between patients with acute pancreatitis and those with chronic ***,drainage of organized necrosis was associated with a significantly higher failure rate than other *** significant differences were observed regarding success when disease,drainage technique,or site of drainage was *** occurred in 13 patients(11%),and there were 6 deaths in the 30 days after drainage,including one that was procedure ***:Endoscopic drainage of pancreatic-fluid collections is successful in the m.jority of patients and is accom.anied by an acceptable com.lication rate.

关键词：胰周积液引流技术内镜下效果比较病因学急性胰腺炎慢性胰腺炎引流术式

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双侧卸货的漏斗车

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铁道车辆译丛 1964年第6期 9-12页

作者： m.delhaye m.Doriot 孙以尧

体重的散装货物在铁路运输上给装卸方法提出了课题,而解决这项课题,其经济价值占着重要因素,且能否适于货主使用,也每每起着决定性的作用。这些货物的装车工作大都集中于有特殊设备的处所——矿埸的高站台、工厂的货仓——

关键词：散装货物漏斗活动顶盖卸货口扁弹簧关阴双侧

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胰腺肿瘤与非肿瘤性组织:定量动态增强m.I和组织病理学参数间的关系

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国际医学放射学杂志 2012年第1期 72-72页

作者： m.A.Bali T.m.tens V.Denolin m.delhaye P.Dem.tter J.Closset 李斌 Departm.nt of Radiology Erasme HospitalUniversité Libre de BruxellesRoute de Lennik 8081070 BrusselsBelgium

目的前瞻性研究动态对比增强(DCE)m.I量化参数与胰腺良、恶性实性占位和非肿瘤性胰腺组织中的纤维化程度和微血管密度(m.D)是否相关。材料与方法本研究获得机构审查委员会批准,并得到所有受检者的书面知情同

关键词：非肿瘤性实性占位纤维化 SCC m.I

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