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Pr.valence and Factor. Associated with r.tavir.s Infection among Vaccinated Childr.n Hospitalized for.Acute Diar.hea in Mwanza City, Tanzania: A Cr.ss Sectional Study

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Open Jour.al of Pediatr.cs 2020年第3期10卷 392-403页

作者： Dina Mahamba Adolfine Hokor.r. Flor.ntina Mashuda delfina r. msanga Elice C. Bender. Elizabeth N. Kwiyolecha Benson r. Kidenya Stephen E. Mshana Mar.am M. Mir.mbo Depar.ment of Pediatr.cs & Child Health College of Health Sciences University of Dodoma Dodoma Tanzania Depar.ment of Pediatr.cs and Child Health Weill Bugando School of Medicine Catholic University of Health and Allied Sciences Mwanza Tanzania Depar.ment of Biochemistr. and Molecular.Biology Weill Bugando School of Medicine Catholic University of Health and Allied Sciences Mwanza Tanzania Depar.ment of Micr.biology and Immunology Weill Bugando School of Medicine Catholic University of Health and Allied Sciences Mwanza Tanzania

Intr.duction: r.tavir.s infection is a leading cause of sever. diar.hea culminating to dehydr.tion among childr.n under.five year. of age. Under.tanding tr.nds and factor. that could assist towar.s devising effective ... 详细信息

r.ng>Intr.duction:r.ng> Rotavirus infection is a leading cause of severe diarrhea culminating to dehydration among children under five years of age. Understanding trends and factors that could assist towards devising effective preventive strategies of Rotavirus infection beyond vaccination is crucial. Objectives: This study was done in an attempt to determine the prevalence and associated factors of Rotavirus infection among vaccinated children aged between 6 weeks and 24 months admitted with acute diarrhea Mwanza, Tanzania. Material and Methods: Across sectional study involving vaccinated children aged 6 weeks to 24 months was conducted in three selected hospitals from July 2017 to January 2018. Socio-demographic and other relevant clinical information were collected using a standardized data collection tool adopted from WHO Rotavirus surveillance tool. Rotavirus infection from the stool was detected using an enzyme immunoassay. Data were analyzed using STATA version 13. Results: A total of 301 vaccinated children with acute diarrhea with a median age of 12 [IQR: 8 - 17] months were enrolled. Nine (3.0%) and 292 (97.0%) had received one dose and two doses of Rotavirus vaccine, respectively. The prevalence of Rotavirus infection was 74 (24.6%) [95% CI: 20.0 - 29.8]. Independent predictors of Rotavirus infection were: dry season (OR 6.9;95% CI: 2.9 -r.ana;"

关键词： r.tavir.s Vaccination Diar.hea

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