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Potential of biocontrol agents against Ganoderma lucidum causing basal stem rot in mesquite(Prosopis cineraria)in arid regions of India

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Journal of Forestry Research 2021年第3期32卷 1269-1279页

作者： Ritu Mawar deepesh sharma Ladhu Ram ICAR-Central Arid Zone Research Institute Jodhpur 342003India College of Horticulture and Forestry JhalarapatanJhalawar 326001India

This study investigates the potential of native biocontrol agents(BCAs)as controls against Ganoderma lucidum causing root rot mortality in Indian *** disease is prevalent in sandy soils where trees grow under rainfed *** addition,a beetle namely A canthophorus serraticornis damages the roots,resulting in increasing vulnerability of the host thereby allowing easy of the *** dual culture tests,Ganoderma infected cowpea root bit experiment and compatibility with insecticides revealed that the three BCAs(Trichoderma longibrachiatum,***,and Aspergillus nidulans)significantly inhibited *** mycelial *** highest mycelial growth inhibition(47.6%)was recorded after 96 h followed by 39.8%and 29.3%at 72 and 48 h,respectively,by *** free filtrates of ***,***,and *** were superior in inhibiting mycelium growth.A low concentration(3 ml)of *** was more effective in inhibiting mycelium growth compared to other *** P rosopis julifl ora compost and onion residue compost amendments as food substrates favored the growth of these BCAs,which ultimately reduced the viability of Ganoderma-colonized root bits of *** on compatibility between insecticides and BCAs suggests that ***,harzianum and *** can be combined with phorate or chloropyriphos(both organophosphates)at variable concentrations if amended together for partially infected trees,or as a prophylactic measure in healthy *** studies demonstrate that there is considerable opportunity for using native BCAs against *** in managing root rot disease.

关键词： Trichoderma longibrachiatum Trichoderma harzianum Aspergillus nidulans Prosopis cineraria Onion residues Prosopis juliflora compost

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Recovery of the injured neural system through gene delivery to surviving neurons in Parkinson’s disease

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Neural Regeneration Research 2025年第10期20卷 2855-2861页

作者： Chanchal sharma Sehwan Kim Hyemi Eo Sang Ryong Kim School of Life Science Kyungpook National UniversityDaeguKorea BK21 FOUR KNU Creative BioResearch Group Kyungpook National University DaeguKorea Brain Science and Engineering Institute Kyungpook National UniversityDaeguKorea

A critical unaddressed problem in Parkinson’s disease is the lack of therapy that slows or hampers *** medications effectively manage symptoms,they offer no long-term benefit because they fail to address the underlying neuronal *** highlights that the elusive goals of halting progression and restoring damaged neurons limit the long-term impact of current *** clinical trials using gene therapy have demonstrated the safety of various vector delivery systems,dosages,and transgenes expressed in the central nervous system,signifying tangible and substantial progress in applying gene therapy as a promising Parkinson’s disease ***,at diagnosis,many dopamine neurons remain in the substantia nigra,offering a potential window for recovery and *** propose that modulating these surviving dopamine neurons and axons in the substantia nigra and striatum using gene therapy offers a potentially more impactful therapeutic approach for future ***,innovative gene therapies that focus on preserving the remaining elements may have significant potential for enhancing long-term outcomes and the quality of life for patients with Parkinson’s *** this review,we provide a perspective on how gene therapy can protect vulnerable elements in the substantia nigra and striatum,offering a novel approach to addressing Parkinson’s disease at its core.

关键词： adeno-associated virus gene therapy neuroprotection neurorestoration neurotrophic factor nigrostriatal dopamine pathway pro-survival protein

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Recognition and quality mapping of traditional herbal drugs:way forward towards artificial intelligence

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Traditional Medicine Research 2025年第1期10卷 12-26页

作者： Sanyam sharma Subh Naman Ashish Baldi Faculty of Pharmacy Pacific Academy of Higher Education and Research UniversityUdaipur 313024India Pharma Innovation Lab Department of Pharmaceutical Sciences and TechnologyMaharaja Ranjit Singh Punjab Technical UniversityBathinda 151001India Faculty of Pharmaceutical Sciences The ICFAI UniversityBaddi 174103India.

The use of traditional herbal drugs derived from natural sources is on the rise due to their minimal side effects and numerous health ***,a major limitation is the lack of standardized knowledge for identifying and mapping the quality of these herbal *** article aims to provide practical insights into the application of artificial intelligence for quality-based commercialization of raw herbal *** focuses on feature extraction methods,image processing techniques,and the preparation of herbal images for compatibility with machine learning *** article discusses commonly used image processing tools such as normalization,slicing,cropping,and augmentation to prepare images for artificial intelligence-based *** also provides an overview of global herbal image databases and the models employed for herbal plant/drug *** will gain a comprehensive understanding of the potential application of various machine learning models,including artificial neural networks and convolutional neural *** article delves into suitable validation parameters like true positive rates,accuracy,precision,and more for the development of artificial intelligence-based identification and authentication techniques for herbal *** article offers valuable insights and a conclusive platform for the further exploration of artificial intelligence in the field of herbal drugs,paving the way for smarter identification and authentication methods.

关键词： artificial intelligence Ayurveda machine learning models herbal drugs image pre-processing medicinal plants

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Chemical, mechanical, and thermal expansion properties of a carbon nanotube-reinforced aluminum nanocomposite

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International Journal of Minerals,Metallurgy and Materials 2016年第2期23卷 222-233页

作者： Manjula sharma Vimal sharma Department of Physics National Institute of Technology Hamirpur

In the present study,the chemical and mechanical properties and the thermal expansion of a carbon nanotube（CNT）-based crystalline nano-aluminum（nano Al） composite were *** properties of nanocomposites were tailored by incorporating CNTs into the nano Al matrix using a physical mixing *** elastic moduli and the coefficient of thermal expansion（CTE） of the nanocomposites were also estimated to understand the effects of CNT reinforcement in the Al *** characterization of the nanocomposite reveals that the CNTs are dispersed and embedded in the Al *** experimental results indicate that the incorporation of CNTs into the nano Al matrix results in the increase in hardness and elastic modulus along with a concomitant decrease in the coefficient of thermal expansion The hardness and elastic modulus of the nanocomposite increase by 21%and 20%,respectively,upon CNT *** CTE of CNT/A1 nanocomposite decreases to 70%compared with that of nano Al.

关键词： metal matrix composites carbon nanotubes nanocomposites chemical properties thermal expansion mechanical properties

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Theoretical Study of Screening Dependence of Aluminium Doped MgB_2

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Chinese Physics Letters 2018年第3期35卷 79-83页

作者： Gargee sharma Smita sharma Department of Physics Government Dungar College

The screening dependence of superconducting state parameters （λ, μ＊, Tc, α and NoV） of six alloys of aluminium doped MgB2 systems are studied in the BCS-Eliashberg-MeMillan framework by employing five forms of dielectric screening function, viz. random phase approximation （RPA）, Harrison, Geldart and Vosko （GV）, Hubbard and Overhauser in conjunction with Ashcroft＇s potential. It is observed that electron-phonon coupling strength and Coulomb pseudopotential μ＊ are quite sensitive to the form of dielectric screening, whereas transition temperature Tc, isotope effect exponent α and effective interaction strength NoV show weak dependence on the form of dielectric screening function. It is found that the RPA form of dielectric screening function yields the best results for transition temperature Tc for all alloys of the Mg-Al-B system. The results obtained using GV screening are much higher than the experimental results. This shows that all the four dielectric screenings used here almost describe superconductivity in all the alloys of the Mg-Al-B system, but the GV screening is not suitable for such an alloy system.

关键词： Theoretical Study of Screening Dependence of Aluminium Doped MgB2 Al

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Manifestation of earthquake preparation zone in the ionosphere before 2021 Sonitpur,Assam earthquake revealed by GPS-TEC data

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Geodesy and Geodynamics 2022年第3期13卷 230-237页

作者： Gopal sharma North Eastern Space Applications Centre Umiam793103MeghalayaIndia

Global Positioning System(GPS)Continuously Operating Reference Station(CORS)data analysis shows that the ionosphere’s electron density variability is linked to the deformation and stress accumulation in the Earth’s *** in ionosphere total electron content(TEC)variability before 2021 M6.4 Sonitpur,Assam earthquake were detected using L1 and L2 GPS frequencies that showed three distinct abnormalities on April 3,9,10,***’s correlation coefficient(r)of TEC decreases in the CORS that lies away from the earthquake epicenter,indicating the possibilities of a positive relationship between TEC variability and earthquake *** concentration also decreases towards the epicenter within the earthquake preparation zone(EPZ).It is also observed that the Pearson’s correlation coefficient(r)of TEC decreases linearly near the *** study demonstrates the possibilities of determining the TEC anomalous zone in the ionosphere that coincides with the EPZ in the crustal *** research indicated the possibilities of magnitude estimation of an impending earthquake based on the TEC anomalous zone in the ionosphere using closely spaced dense CORS network data.

关键词： GPS TEC Sonitpur earthquake Ionosphere perturbation TEC anomaly Magnitude estimation

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Variational Monte Carlo Study of _(ΛΛ)^(4)H

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Chinese Physics Letters 2013年第3期30卷 40-43页

作者： Bhupali sharma Department of Physics Jamia Millia IslamiaNew Delhi-110025India Arya Vidyapeeth College Gauhati UniversityAssamIndia

Variational Monte Carlo calculations are carried out for _(ΛΛ)^(4)H to explore the possibility of its existence,using realistic NN,NNN,and phenomenologicalΛN andΛNN *** also perform calculations using FGNNand NSC97ΛN potentials,and demonstrate the effect of the exchange part of the two-bodyΛN interaction and three-bodyΛNN interaction on the binding energy ofΛΛ*** the stability of _(ΛΛ)^(4)H remains an open question and this hypernuclear system has to be explored more theoretically.

关键词： interaction calculations stability

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Assessment of land use change and its effect on soil carbon stock using multitemporal satellite data in semiarid region of Rajasthan, India

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Ecological Processes 2019年第1期8卷 513-529页

作者： Garima sharma L.K.sharma K.C.sharma Department of Environmental Science Central University of RajasthanNH-8BandarsindriRajasthan 305817India M.D.S.University AjmerRajasthanIndia.

Background:Land use change plays a vital role in global carbon *** land use change impact on soil carbon stock is crucial for implementing land use management to increase carbon stock and reducing carbon ***,the objective of our study was to determine land use change and to assess its effect on soil carbon stock in semi-arid part of Rajasthan,*** temporal satellite data of Pushkar valley region of Rajasthan acquired on 1993,2003,and 2014 were analyzed to assess land use *** trading of land use was depicted *** organic carbon(SOC)stock was calculated for soil to a depth of 30 cm in each land use type in 2014 using field data *** SOC stock for previous years was estimated using stock change *** effect of land use change on SOC stock was determined by calculating change in SOC stock(t/ha)by deducting the base-year SOC stock from the final year stock of a particular land use ***:The total area under agricultural lands was increased by 32.14%while that under forest was decreased by 23.14%during the time period of 1993–*** land use change shows that in both the periods(1993–2003 and 2003–2014),7%of forest area was converted to agricultural land and about 15%changes occurred among agricultural *** 1993–2003,changes among agricultural land led to maximum loss of soil carbon,i.e.,4.88 Mt C and during 2003–2014,conversion of forest to agricultural land led to loss in 3.16 Mt ***:There was a continuous decrease in forest area and increase in cultivated area in each time *** use change led to alteration in carbon equity in soil due to change or loss in ***,we can conclude that the internal trading of land use area during the 10-year period(1993–2003)led to net loss of SOC stock by 8.29 Mt ***,land use change during 11-year period(2003–2014)caused net loss of SOC by 2.76 Mt *** should be made to implement proper land

关键词： Multitemporal satellite data Land use change dynamics Internal trading of land use SOC stock,Stock change factor Change in SOC pool Land use management

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Numerical simulation of square shaped particle sedimentation

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Particuology 2024年第1期84卷 107-116页

作者： Govind sharma Bahni Ray Department of Mechanical Engineering Indian Institute of Technology DelhiHauz KhasNew Delhi110016India

Direct numerical simulations of square particle sedimentation in a viscous incompressible fluid are presented to examine the effects of sharp edges for various particle-to-fluid density ratios and different initial inclination *** settling process exhibits four different motion regimes;non-oscillatory,non-uniform centered oscillatory,uniform off-centered oscillatory,and non-uniform off-centered(irregular)*** moderate density ratios,we observe that the rotational motion of settling square particle varies with the initial inclination *** employ Dynamic Time Warping and Fast Fourier Transform to analyze translational and angular *** systems are described using phase-space plots,and a chaotic phenomenon is observed at a higher density ratio.

关键词： Sedimentation Distributed Lagrangian multiplier Phase synchronization Oscillations

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Instability of binary nanofluids with magnetic field

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Applied Mathematics and Mechanics(English Edition) 2015年第6期36卷 693-706页

作者： U.GUPTA J.sharma V.sharma Dr.S.S.Bhatnagar University Institute of Chemical Engineering and Technology Panjab University Energy Research Centre Panjab University Department of Mathematics Himachal Pradesh University

The present paper investigates the effects of a vertical magnetic field on the double diffusive nanofluid convection, The effects of the Brownian motion and ther- mophoresis due to the presence of nanoparticles and the effects of the Dufour and Sorer parameters due to the presence of solute are included in the investigated model. The normal mode technique is used to solve the conservation equations. For the analytical study, valid approximations are made in the complex expression for the Rayleigh number to get useful and interesting results. The bottom heavy binary nanofluids are more stable than the regular binary fluids, while the top heavy binary nanofluids are less stable than the regular binary fluids. The critical wave number and the critical Rayleigh number in- crease whereas the frequency of oscillation （for the bottom heavy configuration） decreases when the Chandrasekhar number increases. The numerical results for the alumina-water nanofiuid are studied by use of the MATHEMATICA software.

关键词： natural convection binary nanofluid Brownian motion thermophoresis,Chandrasekhar number

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