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Analysis of the urethral stricture score and patient-related factors as predictors of outcomes following oral mucosal graft urethroplasty

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Asian Journal of Urology 2024年第3期11卷 473-479页

作者： Nikita shrivastava Rahul Jena deepak.prak.sh bhirud Mahendra Singh Gautam Ram Choudhary Arjun Singh Sandhu Department of Urology All India Institute of Medical SciencesJodhpurRajasthanIndia

Objective:The complexity of urethral strictures can predict outcomes following *** previously described urethral stricture score(U score)considered only stricture-related factors to grade the complexity of urethral strictures and to predict recurrence post urethroplasty,but not considered patient-related factors for the *** aimed to study the correlation of both of these factors to the outcomes of oral mucosal graft ***:We retrospectively reviewed data of 101 patients who underwent oral mucosal graft urethroplasty in our institute with a minimum follow-up of 6 *** patient characteristics and stricture-related parameters were *** U score was calculated for all patients which consisted of the length,location,number,and etiology of *** and multivariate Cox proportional hazard regression models were used to determine significant risk factors of ***:The mean follow-up of patients was 15 *** was seen in 28 patients and the mean time for detection of recurrence was 8 months of *** Charlson Comorbidity Index,history of previous intervention,length of strictures,location of strictures,number of strictures,history of smoking,and etiology were independent predictors of recurrence following *** on these parameters,we formulated the modified U score(MU score).The scores ranged from 0 to 6 and a score of>2 was found to be predictive of *** comparing receiver operating characteristic curves for both scores by the DeLong test,the MU score had larger area under the curve than the U ***:The MU scoring system is the first of its kind attempt taking into consideration both patient-and stricture-related factors to predict recurrence following oral mucosal graft urethroplasty.

关键词： Urethral stricture Urethral stricture score Recurrence Urethroplasty

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Snow and regolith albedo variations using CRISM data at McMurdo crater,Mars

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Earth and Planetary Physics 2024年第2期8卷 338-355页

作者： Sehajpal Singh deepak Singh Centre of Studies in Resources Engineering Indian Institute of Technology BombayMumbaiIndia

The cryosphere component provides the most reliable and insightful indications of any planet’s climate *** data from the Compact Reconnaissance Imaging Spectrometer for Mars(CRISM),we develop a novel approach to determining the broadband Visible and Near Infrared(VNIR)albedo of the Martian *** study focuses on albedo changes in the McMurdo crater,part of Mars’s south polar layer *** compare seasonal and interannual variations of the McMurdo surface albedo before,during,and after the Global Dust Storm(GDS)of Martian Year(MY)*** the seasons progressed from spring to summer,the mean albedo in MY 32 and 34 plunged by over 40%,by about 35%in MY 33,and by slightly more than 30%in MY *** interannually,however,mean albedo values within both seasons(spring and summer)exhibited no significant differences in those same ***,interannual albedo difference maps reveal albedo variation of more than±0.3 in certain regions of the *** only snow-covered pixels,interannual albedo differences suggest that Mars dust had a pervasive impact on Mars’s *** in maximum and minimum albedo values as high as 0.5 were observed,depending upon differences in the dust levels in Martian snow/*** maximum and the minimum snow albedo values were lowest in MY 34,indicating the effect of the intense dust storm event that *** average snow albedo decreased from 0.45 in MY 32 to 0.40 in MY 33 and to 0.33 in MY 34,and then rose back to 0.40 in MY *** trajectory suggests a temporary deposition of dust,partially reversed after the GDS by self-cleaning mechanisms(local aeolian process and CO_(2)sublimation/deposition cycle).

关键词： Mars Martian ice albedo dust storm Mars surface Martian climate

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Climate change induced heat stress impact on workplace productivity in a net zero-carbon timber building towards the end of the century

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Building Simulation 2024年第6期17卷 893-906页

作者： deepak Amaripadath Mattheos Santamouris shady Attia School of Geographical Sciences and Urban Planning Arizona State UniversityTempeAZUSA Urban Climate Research Center Arizona State UniversityTempeAZUSA School of Built Environment University of New South Wales2052SydneyAustralia Sustainable Building Design Lab Department of UEEFaculty of Applied SciencesUniversity of Liege4000LiegeBelgium

Changing climate intensifies heat stress,resulting in a greater risk of workplace productivity decline in timber office buildings with low internal thermal *** impact of climate change induced heat exposure on indoor workplace productivity in timber office buildings has not been extensively ***,further investigation to reduce the work capacity decline towards the end of the century is ***,heat exposure in a net zero-carbon timber building near Brussels,Belgium,was evaluated using a reproducible comparative approach with different internal thermal mass *** analysis indicated that strategies with increased thermal mass were more effective in limiting the effects of heat exposure on workplace *** medium and high thermal mass strategies reduced workplace productivity loss to 0.1%in the current,0.3%and 0.2%in the midfuture,and 4.9%and 3.9%for future *** comparison,baseline with low thermal mass yielded a decline of 2.3%,3.3%,and 8.2%.The variation in maximum and minimum wet-bulb globe temperatures were also lower for medium and high thermal mass strategies than for low thermal mass *** study findings lead to the formulation of design guidelines,identification of research gaps,and recommendations for future work.

关键词： heat exposure office buildings work capacity thermal mass climate change

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Ethnocultural heritage of the North-Eastern Caucasus as a factor of eco-tourism development

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Journal of Mountain Science 2024年第8期21卷 2810-2824页

作者： Zaburaeva Khava sh. Complex Research Institute named after Kh.I.Ibragimov of the Russian Academy of Sciences Grozny 366002Russia

The North-East Caucasus is a multi-ethnic mountain macroregion with a rich cultural heritage,insufficiently studied in the context of the ecotourism *** fill this gap and identify promising directions of environmentally safe forms of tourism,the author used in-depth review of modern literature to investigate the features of ecological tourism and the problems of preserving ethno-cultural heritage,and used historical and comparative-geographical methods to analyze the development of the tangible and intangible cultural heritage of the indigenous peoples of the North-Eastern Caucasus in different historical periods and to identify the geographical peculiarities of the distribution of historical and cultural monuments(tower buildings),pilgrimage sites and centers of traditional crafts and *** part of the planned expeditions,the author personally visited some historical monuments and handicraft centers for a deeper study of ethno-cultural *** cartographic method made it possible to visualize the *** results of the research show that the ethnocultural heritage of the North-East Caucasus is formed by material(historical and cultural monuments)and immaterial elements of culture(language,customs,traditions,ethnic identification)of those peoples,who live *** ethnocultural heritage is considered as the most important factor in the development of the tourism *** is revealed that this region has a large potential for development in various areas of *** highest concentration of religious buildings focused in mountainous *** tower structures were erected in mountainous and high-altitude *** ancient times to the present day there have been preserved various types of crafts and trades(pottery,metalworking,burka making,jewelry making,carpet weaving,gold embroidery,wood and stone carving,etc.),which can become objects of *** ethnocultural heritage of the North-East Caucasus needs to be preserved a

关键词： Mountainous districts Sustainable development Prospects Stone Towers Folk crafts

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A Comprehensive Survey on Federated Learning in the Healthcare Area: Concept and Applications

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Computer Modeling in Engineering & Sciences 2024年第9期140卷 2239-2274页

作者： deepak Upreti Eunmok Yang Hyunil Kim Changho Seo Department of Convergence Science Kongju National UniversityChungcheongnam-doGongju-si32588South Korea Department of Information Security Cryptologyand MathematicsKookmin UniversitySeoul02707South Korea Department of Information and Communication Engineering Chosun UniversityGwangju61452South Korea Basic Science Research Institution Kongju National UniversityChungcheongnam-doGongju-si32588South Korea

Federated learning is an innovative machine learning technique that deals with centralized data storage issues while maintaining privacy and *** involves constructing machine learning models using datasets spread across several data centers,including medical facilities,clinical research facilities,Internet of Things devices,and even mobile *** main goal of federated learning is to improve robust models that benefit from the collective knowledge of these disparate datasets without centralizing sensitive information,reducing the risk of data loss,privacy breaches,or data *** application of federated learning in the healthcare industry holds significant promise due to the wealth of data generated from various sources,such as patient records,medical imaging,wearable devices,and clinical research *** research conducts a systematic evaluation and highlights essential issues for the selection and implementation of federated learning approaches in *** evaluates the effectiveness of federated learning strategies in the field of *** offers a systematic analysis of federated learning in the healthcare domain,encompassing the evaluation metrics *** addition,this study highlights the increasing interest in federated learning applications in healthcare among scholars and provides foundations for further studies.

关键词： Federated learning artificial intelligence machine learning privacy healthcare

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Emerging roles of microRNAs as diagnostics and potential therapeutic interest in type 2 diabetes mellitus

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World Journal of Clinical Cases 2024年第3期12卷 525-537页

作者： Dharmsheel shrivastav Desh deepak Singh Amity Institute of Biotechnology Amity University RajasthanJaipur 303002India

BACKGROUND Type 2 diabetes mellitus(T2DM)is a metabolic disease of impaired glucose *** high sugar levels lead to advanced glycation end products(AGEs),which affects several metabolic pathways by its receptor of advanced glycation end products(RAGE)and causes diabetic *** are small RNA molecules which regulate genes linked to diabetes and affect AGEs pathogenesis,and target tissues,influencing health and disease *** To explore miRNA roles in T2DM's metabolic pathways for potential therapeutic and diagnostic advancements in diabetes *** We systematically searched the electronic database PubMed using *** included free,full-length research articles that evaluate the role of miRNAs in T2DM and its complications,focusing on genetic and molecular disease *** assessing the full-length papers of the shortlisted articles,we included 12 research *** Several types of miRNAs are linked in metabolic pathways which are affected by AGE/RAGE axis in T2DM and its ***-96-5p,miR-7-5p,miR-132,has_circ_0071106,miR-143,miR-21,miR-145-5p,and more are associated with various aspects of T2DM,including disease risk,diagnostic markers,complications,and gene *** Targeting the AGE/RAGE axis,with a focus on miRNA regulation,holds promise for managing T2DM and its *** have therapeutic potential as they can influence the metabolic pathways affected by AGEs and RAGE,potentially reducing inflammation,oxidative stress,and vascular ***,miRNAs may serve as early diagnostic biomarkers for *** research in this area may lead to innovative therapeutic strategies for diabetes and its associated complications.

关键词： Type 2 diabetes mellitus MicroRNAs Advanced glycation end products Receptor for advanced glycation end products

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Efficient Finite Difference WENO Scheme for Hyperbolic Systems withNon-conservativeProducts

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Communications on Applied Mathematics and Computation 2024年第2期6卷 907-962页

作者： Dinshaw S.Balsara deepak Bhoriya Chi-Wang shu Harish Kumar Physics Department University of Notre DameNotre DameUSA ACMS Department University of Notre DameNotre DameUSA Division of Applied Mathematics Brown UniversityProvidenceUSA Department of Mathematics Indian Institute of TechnologyDelhiIndia

Higher order finite difference weighted essentially non-oscillatory(WENO)schemes have been constructed for conservation *** multidimensional problems,they offer a high order accuracy at a fraction of the cost of a finite volume WENO or DG scheme of the comparable *** makes them quite attractive for several science and engineering ***,to the best of our knowledge,such schemes have not been extended to non-linear hyperbolic systems with non-conservative *** this paper,we perform such an extension which improves the domain of the applicability of such *** extension is carried out by writing the scheme in fluctuation *** use the HLLI Riemann solver of Dumbser and Balsara(***.304:275-319,2016)as a building block for carrying out this *** of the use of an HLL building block,the resulting scheme has a proper supersonic *** use of anti-diffusive fluxes ensures that stationary discontinuities can be preserved by the scheme,thus expanding its domain of the *** new finite difference WENO formulation uses the same WENO reconstruction that was used in classical versions,making it very easy for users to transition over to the present *** conservation laws,the new finite difference WENO is shown to perform as well as the classical version of finite difference WENO,with two major advantages:(i)It can capture jumps in stationary linearly degenerate wave families exactly.(i)It only requires the reconstruction to be applied *** examples from hyperbolic PDE systems with non-conservative products are shown which indicate that the scheme works and achieves its design order of the accuracy for smooth multidimensional *** Riemann problems and several novel multidimensional problems that are drawn from compressible Baer-Nunziato multiphase flow,multiphase debris flow and twolayer shallow water equations are also shown to document the robustness of the *** some

关键词： Hyperbolic PDEs Numerical schemes Non-conservative products Stiff source terms Finite difference WENO

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Guest Editorial:Special issue on trustworthy machine learning for behavioural and social computing

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CAAI Transactions on Intelligence Technology 2024年第3期9卷 541-543页

作者： Zhi-Hui Zhan Jianxin Li Xuyun Zhang deepak Puthal Nankai University TianjinChina Deakin University BurwoodVictoriaAustralia Macquarie University SydneyNew South WalesAustralia Khalifa University Abu DhabiUAE

Machine learning has been extensively applied in behavioural and social computing,encompassing a spectrum of applications such as social network analysis,click stream analysis,recommendation of points of interest,and sentiment *** datasets pertinent to these applications are inherently linked to human behaviour and societal dynamics,posing a risk of disclosing personal or sensitive information if mishandled or subjected to attacks.

关键词： computing handle learning

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Debate on direct-anterior vs posterior approach for hip hemiarthroplasty:The authors’insights

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World Journal of Orthopedics 2024年第5期15卷 486-488页

作者： deepak Kumar Tarkik Thami Manjunath Nishani Department of Orthopedics Post Graduate Institute of Medical Education and ResearchChandigarh 160012India

We read and discussed the study entitled“Complication rates after direct anterior vs posterior approach for Hip Hemiarthroplasty in elderly individuals with femoral neck fractures”with great *** authors have done justice to the topic of comparison of anterior and posterior surgical approaches for bipolar hemiarthroplasty which has been an everlasting debate in the existing ***,there are certain aspects of this study that need clarification from the authors.

关键词： Commentary Direct anterior approach Posterior approach Hip hemiarthroplasty

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Natural product-based treatment potential for type 2 diabetes mellitus and cardiovascular disease

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World Journal of Diabetes 2024年第7期15卷 1603-1614页

作者： Dharmsheel shrivastav Satyam Kumar Kumbhakar shivangi Srivastava Desh deepak Singh Amity Institute of Biotechnology Amity University RajasthanJaipur 303002RajasthanIndia Department of Biotechnology Govt Veer Surendra Say P.G.CollegeGariaband 493889ChhattisgarhIndia Department of Life Science Chhatrapati Shahu ji Maharaj UniversityKanpur 208024Uttar PradeshIndia

BACKGROUND Type 2 diabetes(T2D)is a metabolic disease of impaired glucose utilization and a major cause of cardiovascular disease(CVD).The pathogenesis of both diseases shares common risk factors and mechanisms,and both are significant contributors to global morbidity and *** of natural products for T2D mellitus(T2DM)and CVD can be seen as a potential preventive and effective therapeutic *** To critically evaluate the therapeutic potential of natural products in T2D and coronary artery disease(CAD).METHODS By using specific keywords,we strategically searched the PubMed *** controlled trials(RCTs)were searched as the primary focus that examined the effect of natural products on glycemic control,oxidative stress,and antioxidant *** focused on outcomes such as low blood glucose levels,adjustment on markers of oxidative stress and *** screening fulllength papers,we included 9 RCTs in our review that met our inclusion *** In the literature search on the database,we found that various natural products like plant secondary metabolites play a diverse role in the management of *** ginseng,sesame oil and cocoa flavanols proved effective in lowering blood glucose levels and controlling blood pressure,which are key factors in managing T2DM and *** diabetic patients Melissa officinalis effectively reduce inflammation and shows diabetes *** fish oil and flaxseed oil reduced insulin levels and inflammatory markers,suggesting benefits for both *** lipid profile and endothelial function were enhanced by Nigella sativa oil and Terminalia chebula,which is significant for the management of cardiovascular risk factors in *** Bilberry extract also showed promise for improving glycemic control in patients with *** The high level of antioxidant,anti-inflammatory,and anti-angiogenic properties found in natural products makes them promising therapeutic opt

关键词： Type 2 diabetes mellitus Cardiovascular disease Natural products Antioxidants Oxidative stress Therapeutic impact Global burden

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