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A prototype online database-enabled design framework for wind analysis/design of low-rise buildings

Frontiers of Structural and Civil Engineering 2016年第1期10卷 121-130页

作者： Dae Kun KWON Ahsan KAREEM deepak kumar Yukio TAMURA NatHaz Modeling Laboratory Department of Civil & Environmental Engineering & Earth Sciences University of Notre DameNotre Dame IN 46556 USA Department of Ocean Engineering Indian Institute of Technology Madras Chennai 600036 India Department of Architectural Engineering Tokyo Polytechnic University Tokyo 243-0297 Japan

This study presents a development of an advanced cyberbased database-enabled design module for low- rise buildings （DEDM-LR） which provides estimation of the wind-induced responses for main wind force resisting frames by making direct use of pressure time histories measured at a large number of pressure taps over a suite of building models. These responses may be considered in lieu of code-specified load effects in which the overall accuracy may be influenced by the inherent simplifications in codes. In addition, this new automated approach is particularly attractive and advantageous as it allows a web-based online analysis/design via intuitive user-friendly interfaces for both the input and output in terms of familiar web-style forms that are nowadays very common in most of web-based services. Presently, the DEDM-LR hosts an aerodynamic database developed by the Tokyo Polytechnic University （TPU）, Japan for a variety of building configurations like flat, gable, and hip roofs under suburban terrain flow condition with immediate application to other databases. The paper shows the efficacy and validity of the DEDM-LR by walking through its details and examples on selected gable-roofed buildings. The architecture of DEDM-LR platform offers the ability to pool resources by hosting other databases that may become available in the near future.

关键词： wind loads low-rise building pressure measurement aerodynamics building design structural response,building codes information technology (IT)

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Constitutive modeling of particle reinforced rubber-like materials

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Theoretical & Applied Mechanics Letters 2022年第6期12卷 419-422页

作者： Sankalp Gour deepak kumar Department of Mechanical Engineering Maulana Azad National Institute of Technology BhopalMadhya Pradesh462003India

The present study is focused on the constitutive modeling for the mechanical behavior of rubber reinforced with filler particles.A filler-dependent energy density function is proposed with all the continuum mechanics-based necessities of an effective hyperelastic material *** proposed invariant-based energy function comprises a single set of material parameters for a material subjected to several modes of loading *** model solution agrees well with existing experimental ***,the effect of varying concentrations of filler particles in the rubber matrix is also studied.

关键词： Hyperelastic material Constitutive modeling Strain energy function

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Multilevel Augmentation for Identifying Thin Vessels in Diabetic Retinopathy Using UNET Model

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Intelligent Automation & Soft Computing 2023年第2期35卷 2273-2288页

作者： A.deepak kumar T.Sasipraba Faculty of Computer Science and Engineering Sathyabama Institute of Science and TechnologyChennai600119India Department of Computer Science and Engineering St.Joseph’s Institute of TechnologyChennai600119India

Diabetic Retinopathy is a disease,which happens due to abnormal growth of blood vessels that causes spots on the vision and vision *** techniques are applied to identify the disease in the early stage with different methods and *** Learning(ML)techniques are used for analyz-ing the images andﬁnding out the location of the *** restriction of the ML is a dataset size,which is used for model *** problem has been overcome by using an augmentation method by generating larger datasets with multidimensional *** models are using only one augmentation tech-nique,which produces limited features of dataset and also lacks in the association of those data during DR detection,so multilevel augmentation is proposed for *** proposed method performs in two phases namely integrated aug-mentation model and dataset correlation(***).It eliminates overﬁt-ting problem by considering relevant *** method is used for solving the Diabetic Retinopathy problem with a thin vessel identiﬁcation using the UNET *** based image segmentation achieves 98.3%accuracy when com-pared to RV-GAN and different UNET models with high detection rate.

关键词： Image segmentation diabetic retinopathy image augmentation semantic segmentation CNN

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Acclimatization of microalgae Arthrospira platensis for treatment of heavy metals in Yamuna River

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Water Science and Engineering 2020年第3期13卷 214-222页

作者： Nilesh kumar Shriya Hans Ritu verma Aradhana Srivastava University School of Chemical Technology Guru Gobind Singh Indraprastha UniversityNew Delhi 110078India

Bioaccumulation and biosorption in microalgae are effective approaches for the removal of heavy metals(HMs)from river *** objective of this study was to investigate the potential for use of acclimatized microalgae in the removal of HMs from the Yamuna River water as an acclimatizing *** active culture of Arthrospira platensis(***)was acclimatized to HMs up to a concentration of 100 mg/*** was gradually exposed to increasing concentrations of HMs in five subsequent batches with a step increase of 20 mg/L to acclimatize live cells in the simulated Yamuna River *** presence of high levels of HMs in the Yamuna River water caused growth *** empirical growth inhibition model was developed,and it predicted high threshold concentrations of HMs(210.7e424.5 mg/L),producing a positive specific growth rate of *** also showed high average removal efficiencies of HMs,including 74.0%for Cu,77.0%for Cd,50.5%for Ni,76.0%for Cr,76.5%for Pb,and 63.5%for Co,from HMs-enriched Yamuna River *** findings demonstrated that the maximum specific removal amounts of Cu,Cd,Ni,Cr,Pb,and Co were 54.0,58.0,39.0,62.8,58.9,and 45.3 mg/g,*** maximum yields of the value-added products chlorophyll and phycocyanin were 2.5 mg/g(in a batch of 40 mg/L for Cd)and 1054 mg/g(in a batch of 20 mg/L for Cu),***,acclimatized *** was proven to be a potential microalga not only for sequestration of HMs but also for production of valuable pigments.

关键词： Yamuna River A.platensis Heavy metals Acclimatization Biosorption Pigments

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SARS-CoV-2 infection in people with pre-existing liver disease:Further research is warranted

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World Journal of Gastroenterology 2021年第45期27卷 7855-7858页

作者： Henu kumar verma LVKS Bhaskar Department of Immunopathology Institute of lungs Biology and DiseaseComprehensive Pneumology CenterNeuherberg 85764MunichGermany Zoology Guru Ghasidas VishwavidyalayaBilaspur 495001ChhattisgarhIndia

Patients with severe liver disease who have been infected with severe acute respiratory syndrome coronavirus-2(coronavirus disease 2019)frequently develop acute respiratory distress syndrome and multiple organ failure,with a high mortality rate,as a result of the hyper-proinflammatory state known as the cytokine *** must recognize cytokine storms earlier to avoid intensive care admission and multi-organ damage,a critical life-threatening condition with prognostic and therapeutic implications.

关键词： Cytokine storm Liver disease Angiotensin-converting enzyme 2 Therapeutics Inflammatory markers

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Gender differences in the relationship between alcohol consumption and gastric cancer risk are uncertain and not well-delineated

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World Journal of Gastrointestinal Oncology 2021年第12期13卷 2216-2218页

作者： Henu kumar verma LVKS Bhaskar Department of Immunopathology Institute of lungs Biology and DiseaseComprehensive Pneumology CenterHelmholtz ZentrumNeuherberg 85764MunichGermany Department of Zoology Guru Ghasidas VishwavidyalayaBilaspur 495001ChhattisgarhIndia

The role of alcoholic and other beverage consumption in the etiology of gastric cancer is *** studies have summarized and established a significant association between heavy alcohol consumption and gastric cancer risk... 详细信息

关键词： Alcohol Gastric cancer Meta-analysis Gender and alcohol intake Alcohol consumption

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Analysis on Krasnoselskii’s fixed point theorem of fuzzy variable fractional differential equation for a novel coronavirus(COVID-19)model with singular operator

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International Journal of Modeling, Simulation, and Scientific Computing 2021年第3期12卷 150-166页

作者： Pratibha verma Manoj kumar Anand Shukla Department of Mathematics Motilal Nehru National Institute of Technology Allahabad Prayagraj 211004 Uttar PradeshIndia Department of Mathematics Wollega UniversityEthiopia

The fuzzy variable fractional differential equations(FVFDEs)play a very important role in mathematical modeling of *** scientists are studying and developing several aspects of these COVID-19 *** existence and uniqueness of the solution,stability analysis are the most common and important study *** is no study in the literature to establish the existence,uniqueness,and UH stability for fuzzy variable fractional(FVF)order COVID-19 *** to high demand of this study,we investigate results for the existence,uniqueness,and UH stability for the considered COVID-19 model based on FVFDEs using a fixed point theory approach with the singular ***,discuss the maximal/minimal solution for the FVFDE of the COVID-19 model.

关键词： Novel coronavirus(COVID-19) variable Caputo fractional derivative fixed point theorem existence and uniqueness Ulam-Hyers stability

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Ulam-Hyers stability and analytical approach for m-dimensional Caputo space-time variable fractional order advection-dispersion equation

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International Journal of Modeling, Simulation, and Scientific Computing 2022年第1期13卷 131-174页

作者： Pratibha verma Manoj kumar Anand Shukla Department of Mathematics Motilal Nehru National Institute of Technology Allahabad Prayagraj–211004 Uttar PradeshIndia†Department of Mathematics Wollega UniversityNekemteEthiopia

This article introduces the computational analytical approach to solve the m-dimensional space-time variable Caputo fractional order advection–dispersion equation with the Dirichlet boundary using the two-step Adomian decomposition method and obtain the exact solution in just one ***,with the help of fixed point theory,we study the existence and uniqueness conditions for the positive solution and prove some new ***,obtain the Ulam–Hyers stabilities for the proposed *** gen-eralized examples are considered to show the method’s applicability and compared with other existing numerical *** present method performs exceptionally well in terms of efficiency and ***,we solved both examples using the two most well-known numerical methods and compared them with the TSADM solution.

关键词： Fixed point theorems space-time variable Caputo’s fractional operators advection-dispersion equation Ulam-Hyers stability two-step Adomian decomposition method

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Targeting brain tumors with innovative nanocarriers:bridging the gap through the blood-brain barrier

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Oncology Research 2024年第5期32卷 877-897页

作者： KARAN WADHWA PAYAL CHAUHAN SHOBHIT kumar RAKESH PAHWA RAVINDER verma RAJAT GOYAL GOVIND SINGH ARCHANA SHARMA NEHA RAO deepak KAUSHIK Department of Pharmaceutical Sciences Maharshi Dayanand UniversityRohtak124001India Department of Pharmaceutical Technology Meerut Institute of Engineering and Technology(MIET)NH-58Delhi-Roorkee HighwayMeerut250005India Institute of Pharmaceutical Sciences Kurukshetra UniversityKurukshetra136119India Department of Pharmaceutical Sciences Chaudhary Bansi Lal UniversityBhiwani127021India MM College of Pharmacy Maharishi Markandeshwar(Deemed to be University)Mullana-AmbalaHaryana133207India Delhi Pharmaceutical Sciences and Research University(DIPSAR) Delhi Pharmaceutical Sciences and Research UniversityNew Delhi110017India

Background:Glioblastoma multiforme(GBM)is recognized as the most lethal and most highly invasive *** high likelihood of treatment failure arises fromthe presence of the blood-brain barrier(BBB)and stemcells around GBM,which avert the entry of chemotherapeutic drugs into the ***:Recently,several researchers have designed novel nanocarrier systems like liposomes,dendrimers,metallic nanoparticles,nanodiamonds,and nanorobot approaches,allowing drugs to infiltrate the BBB more efficiently,opening up innovative avenues to prevail over therapy problems and radiation ***:Relevant literature for this manuscript has been collected from a comprehensive and systematic search of databases,for example,PubMed,Science Direct,Google Scholar,and others,using specific keyword combinations,including“glioblastoma,”“brain tumor,”“nanocarriers,”and several ***:This review also provides deep insights into recent advancements in nanocarrier-based formulations and technologies for GBM *** of various scientific advances in conjunction with encouraging findings concerning the future perspectives and challenges of nanocarriers for effective brain tumor management has also been discussed.

关键词： Glioblastoma Brain tumor Blood-brain barrier Liposomes Metallic nanoparticles Nanocarriers

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Humans and Robots: A Mutually Inclusive Relationship in a Contagious World

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International Journal of Automation and computing 2021年第2期18卷 185-203页

作者： Akash Gupta Anshuman Singh deepak Bharadwaj Amit kumar Mondal Department of Mechanical Engineering University of Petroleum and Energy StudiesDehradun 248007India Department of Systems Engineering University of MarylandCollege ParkMaryland 20742USA Department of Mechatronics Engineering Manipal Academy of Higher EducationDubai 345050UAE

The coronavirus global pandemic has spread faster and more severely than experts had *** this has presented itself as a great challenge,researchers worldwide have shown ingenuity and dexterity in adapting technology and devising new strategies to combat this ***,implementing these strategies alone impedes the nature of everyone′s daily ***,an intersection between these strategies and the technological advantages of robotics,artificial intelligence,and autonomous systems is essential for near-to-normal *** this review paper,different applications of robotic systems,various aspects of modern technologies,including medical imaging,telemedicine,and supply chains,have been covered with respect to the COVID-19 ***,concerns over user′s data privacy,job losses,and legal aspects of the implementation of robotics are also been discussed.

关键词： COVID-19 coronavirus telepresence delivery robots medical robots

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