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New insights into nitric oxide biosynthesis underpin lateral root development

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Molecular Plant 2024年第5期17卷 691-693页

作者： Kapuganti Jagadis Gupta Nidhi yadav Aprajita kumari Gary J.Loake National Institute for Plant Genome Research Aruna Asaf Ali MargNew Delhi 110070India Institute of Molecular Plant Sciences School of Biological SciencesUniversity of EdinburghEH93BF EdinburghUK Centre for Engineering Biology School of Biological SciencesUniversity of EdinburghEH93BF EdinburghUK

In recent years,nitric oxide(NO)has emerged as a key redox signaling molecule in plants functioning in the regulation of key developmental programs and the orchestration of responses to a plethora of environmental cues(Kolbert et al.,2019).The predominant route for the transfer of NO bioactivity is through S-nitrosylation,the addition of an NO moiety to a protein cysteine thiol to form an S-nitrosothiol(Yun et al.,2011).Specificity for this process is established by the structural constraints imposed by tertiary protein structure in gating access to given cysteine redox switches and associated proteins that can either facilitate the addition or removal of the NO moiety at these residues(Umbreen et al.,2018).

关键词： moiety addition redox

ERCC1 expression in patients with colorectal cancer:a pilot study

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Journal of Cancer Metastasis and Treatment 2016年第1期2卷 471-476页

作者： Kinjal K.Gajjar deep kumari yadav Toral P.Kobawala Trupti I.Trivedi Hemangini H.Vora Nandita R.Ghosh Cancer Biology Department the Gujarat Cancer and Research InstituteNCH CompoundAsarwaAhmedabad 380016GujaratIndia Immunohistochemistry and Flow Cytometry Division Cancer Biology DepartmentThe Gujarat Cancer and Research InstituteNCH CompoundAsarwaAhmedabad 380016GujaratIndia

Aim:Excision repair cross complementation group 1(ERCC1)has a key role in enhanced DNA damage repair caused by oxaliplatin-based therapy and may lead to resistance of these platinum drugs in colorectal cancer(CRC)***,the present preliminary study aimed to explore the role of ERCC1 C/T polymorphism at codon 118 as well as its immunoreactivity in patients with primary ***:ERCC1 polymorphism was studied using PCR-RFLP and ERCC1 protein expression was examined by immunohistochemistry in 50 CRC ***:ERCC1 codon 118 C/T polymorphism analysis reported the predominance of C/T(52%)genotype as compared to C/C(38%)and T/T(10%)***,72%of patients showed positive ERCC1 protein *** correlation was not observed between clinicopathological parameters and ERCC1 polymorphism,while ERCC1 protein expression significantly correlated only with tumor site(colon ***)(P=0.046).Further,the present study failed to demonstrate the role of ERCC1 C118T polymorphism or protein expression as useful prognostic markers in CRC ***:ERCC1-positive protein expression may be a useful marker for rectal cancer ***,further evaluation in a larger set of CRC patients is required to better understand the role of ERCC1.

关键词： Excision repair cross complementation group 1 oxaliplatin colorectal cancer polymorphism protein expression PCR-RFLP immunohistochemistry

Anticancer Activity of Rice Callus Suspension Cultures from Aromatic Varieties and Metabolites Regulated in Treated Cancer Cell Lines

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Rice science 2024年第4期31卷 449-462,I0027-I0030页

作者： Anuradha kumari Wusirika RAMAKRISHNA Department of Biochemistry Central University of PunjabPunjab 151401India

Tissue culture techniques were used to produce large amounts of bioactive compounds with medicinal potential, overcoming space and time constraints for cancer prevention. Rice callus suspension cultures(RCSC) and seed extracts prepared from aromatic rice varieties were used to evaluate the cytotoxic impact on human colon and lung cancer cell lines, as well as a normal control cell line, using Taxol as a positive control. RCSC and seed extracts from two Indian aromatic rice varieties were applied at different concentrations to treat the cancer cell lines and normal lung fibroblasts over varying time intervals. Apoptosis was assessed in 1:5 dilutions of the A549 and HT-29 cell lines treated with RCSC for 72 h, using propidium iodide staining and flow cytometry. RCSC showed a more potent cytotoxic effect than seed extracts with minimal effect on the normal cell line, in contrast to Taxol. Confocal microscopy and flow cytometry further confirmed the apoptotic effect of RCSC. Gas chromatography-mass spectrometry-based metabolic profiling identified metabolites involved in cytotoxicity and highlighted altered pathways. RCSC is proposed as an alternative source for the development of novel anticancer drugs with reduced side effects.

关键词： anticancer cytotoxicity metabolite profiling plant tissue culture rice callus suspension culture secondary metabolite

MXenes: Versatile 2D materials with tailored surface chemistry and diverse applications

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Journal of Energy Chemistry 2024年第3期90卷 253-293,I0008页

作者： Sunil Kumar Nitu kumari Yongho Seo Department of Nanotechnology and Advanced Materials Engineering and HMC Sejong UniversitySeoul 05006South Korea School of Studies in Chemistry Jiwaji UniversityGwalior 474011India

MXenes,the most recent addition to the 2D material family,have attracted significant attention owing to their distinctive characteristics,including high surface area,conductivity,surface characteristics,mechanical strength,*** review begins by presenting MXenes,providing insights into their structural characteristics,synthesis methods,and surface functional *** review covers a thorough analysis of MXene surface properties,including surface chemistry and termination group *** properties of MXenes are influenced by their synthesis,which can be fluorine-based or ***-based synthesis techniques involve etching with fluorine-based reagents,mainly including HF or LiF/HCl,while fluorine-free methods include electrochemical etching,chemical vapor deposition(CVD),alkaline etching,Lewis acid-based etching,*** techniques result in the emergence of functional groups such as-F,-O,-OH,-Cl,*** the MXenes surface,depending on the synthesis method *** of MXenes,such as electrical conductivity,electronic properties,catalytic activity,magnetic properties,mechanical strength,and chemical and thermal stability,are examined,and the role of functional groups in determining these properties is *** review delves into the diverse applications of MXenes,encompassing supercapacitors,battery materials,hydrogen storage,fuel cells,electromagnetic interference(EMI) shielding,pollutant removal,water purification,flexible electronics,sensors,additive manufacturing,catalysis,biomedical and healthcare fields,***,this article outlines the challenges and opportunities in the current and future development of MXenes research,addressing various aspects such as synthesis scalability,etching challenges,and multifunctionality,and exploring novel *** review concludes with future prospects and conclusions envisioning the impact of MXenes on future technologies and innovation.

关键词： MXenes 2D materials Surface chemistry MXenes structure Synthesis Applications

Rayleigh wave propagation with two temperature and diffusion in context of three phase lag thermoelasticity

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Journal of Ocean Engineering and Science 2024年第4期9卷 317-325页

作者： Mandeep Singh Sangeeta kumari Department of Mathematics Chandigarh UniversityGharuan(Mohali)PunjabIndia

The primary objective of this research problem is to analyze the Rayleigh wave propagation in homogeneous isotropic half space with mass diffusion in Three Phase Lag(TPL)thermoelasticity at two *** governing equations of thermodiffusive elastic half space have been solved using the normal mode analysis in order to obtain the Rayleigh wave frequency equation at relevant boundary *** variation of various parameters like non-dimensional speed,attenuation coefficient,penetration depth and specific loss corresponding to thermodiffusion parameter,relaxation time,wave number and frequency has been *** effect of these parameters on Rayleigh wave propagation in thermoelastic half space are graphically demonstrated and variations of all these parameters have been compared within Lord-Shulman(L-S),Green-Nagdhi(GN-III)and Three Phase Lag(TPL)theory of thermoelasticity.

关键词： Rayleigh waves Attenuation coefficient Normal mode analysis Thermoelasticity Diffusion Three phase lag

Scenario of solar energy and policies in India

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Clean Energy 2024年第5期8卷 117-128页

作者： Sathish Kumar M Prity kumari Y.A.Lad Sherin Maria Teaching Assistant Symbiosis Institute of Business ManagementSymbiosis International(Deemed)UniversityNagpur440008MaharashtraIndia Assistant Professor and Head Department of Basic ScienceCollege of HorticultureAnand Agricultural UniversityAnand388110GujaratIndia Associate Professor&Head Department of HRD&PMInternational Agribusiness Management InstituteAnand Agricultural UniversityAnand388110GujaratIndia Research Assistant International Maize and Wheat Improvement Center(CIMMYT)HyderabadTelanganaIndia

Solar power is energy from the Sun that is converted into thermal or electrical ***,the USA,and India have the world’s richest solar energy *** receives solar radiation with an average intensity of 200 MW/km^(2) and 250–300 sunny days a *** solar radiation in India varies from 4 to 7 kWh/m^(2)/day,with 2300–3200 sunshine hours yearly,depending on the *** Solar Park,Jodhpur,India,is the world’s largest solar plant,with 2.25 GW of installed *** energy is the best alternative elec-tricity source used explicitly in the agricultural *** the farming sector,the consumption of solar energy has been *** major issues were the installation costs,low availability of technicians,and poor quality of *** focus on skill development equips the workforce to drive innovation,efficiency,and sustained growth in the renewable-energy *** the support of inter-national collaboration and a skilled workforce,India’s progress in solar energy development is a boon for the industry.

关键词： solar energy benefits policies challenges achievements

A Spectral Convolutional Neural Network Model Based on Adaptive Fick’s Law for Hyperspectral Image Classification

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Computers, Materials & Continua 2024年第4期79卷 19-46页

作者： Tsu-Yang Wu Haonan Li Saru kumari Chien-Ming Chen School of Artificial Intelligence(School of Future Technology) Nanjing University of Information Science&TechnologyNanjing210044China College of Computer Science and Engineering Shandong University of Science and TechnologyQingdao266590China Department of Mathematics Chaudhary Charan Singh UniversityMeerutUttar Pradesh250004India

Hyperspectral image classification stands as a pivotal task within the field of remote sensing,yet achieving highprecision classification remains a significant *** response to this challenge,a Spectral Convolutional Neural Network model based on Adaptive Fick’s Law Algorithm(AFLA-SCNN)is *** Adaptive Fick’s Law Algorithm(AFLA)constitutes a novel metaheuristic algorithm introduced herein,encompassing three new strategies:Adaptive weight factor,Gaussian mutation,and probability update *** adaptive weight factor,the algorithmcan adjust theweights according to the change in the number of iterations to improve the performance of the *** helps the algorithm avoid falling into local optimal solutions and improves the searchability of the *** probability update strategy helps to improve the exploitability and adaptability of the *** the AFLA-SCNN model,AFLA is employed to optimize two hyperparameters in the SCNN model,namely,“numEpochs”and“miniBatchSize”,to attain their optimal ***’s performance is initially validated across 28 functions in 10D,30D,and 50D for CEC2013 and 29 functions in 10D,30D,and 50D for *** results indicate AFLA’s marked performance superiority over nine other prominent optimization ***,the AFLA-SCNN model was compared with the Spectral Convolutional Neural Network model based on Fick’s Law Algorithm(FLA-SCNN),Spectral Convolutional Neural Network model based on Harris Hawks Optimization(HHO-SCNN),Spectral Convolutional Neural Network model based onDifferential Evolution(DE-SCNN),SpectralConvolutionalNeuralNetwork(SCNN)model,and SupportVector Machines(SVM)model using the Indian Pines dataset and PaviaUniversity *** experimental results show that the AFLA-SCNN model outperforms other models in terms of Accuracy,Precision,Recall,and F1-score on Indian Pines and Pavia *** them,the Accuracy of the AFLA-SCNN model on India

关键词： Adaptive Fick’s law algorithm spectral convolutional neural network metaheuristic algorithm intelligent optimization algorithm hyperspectral image classification

Microalgal bioinoculants for sustainable agriculture and their interactions with soil biotic and abiotic components:A review

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Pedosphere 2024年第2期34卷 297-314页

作者： Shisy JOSE Nirmal RENUKA Sachitra Kumar RATHA Sheena kumari Faizal BUX Institute for Water and Wastewater Technology Durban University of TechnologyP.O.Box 1334Durban 4000South Africa Algal Biotechnology Laboratory Department of BotanyCentral University of PunjabBathinda 151401India Phycology Laboratory Council of Scientific and Industrial Research-National Botanical Research InstituteLucknowUttar Pradesh 226001India

Modern agricultural practices have posed a detrimental impact on the environment due to their intensive use to meet the food demands of an ever-increasing *** this context,microalgal bioinoculants,specifically cyanobacteria and green microalgae,have emerged as sustainable options for agricultural practices to improve soil organic carbon,nutrient availability,microbial quality,and plant *** overview of current and future perspectives on the use of microalgal bioinoculants in agriculture practices is presented in this review,along with a discussion of their interactions with soil biotic and abiotic factors that affect soil fertility,plant health,and crop *** benefits of microalgal bioinoculants include releasing agronomically important metabolites(exopolymers and phytohormones)as well as solubilizing soil ***,they function as biocontrol agents against soil-borne pathogens and facilitate the establishment of rhizosphere communities of agricultural *** far,very few studies have explored the basic mechanisms by which microalgal bioinoculants interact with soil biotic and abiotic *** recent years,advanced molecular techniques have contributed to a better understanding of these interactions.

关键词： biocontrol agent biofertilizer cyanobacteria microalgae microbial community molecular technique plant growth soil fertility

Electrokinetic-mechanism of water and furfural oxidation on pulsed laser-interlaced Cu_(2)O and CoO on nickel foam

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Journal of Energy Chemistry 2024年第4期91卷 145-154页

作者： Yewon Oh Jayaraman Theerthagiri M.L.Aruna kumari Ahreum Min Cheol Joo Moon Myong Yong Choi Department of Chemistry(BK21 FOUR) Research Institute of Natural SciencesGyeongsang National UniversityJinju 52828Republic of Korea Department of Chemistry The Oxford College of ScienceBengaluruKarnataka 560102India Core-Facility Center for Photochemistry&Nanomaterials Gyeongsang National UniversityJinju 52828Republic of Korea

The electrocatalytic oxidation of biomass-derived furfural(FF)feedstocks into 2-furoic acid(FA)holds immense industrial potential in optics,cosmetics,polymers,and ***,we fabricated Co O/Ni O/nickel foam(NF)and Cu_(2)O/Ni O/NF electrodes via in situ pulsed laser irradiation in liquids(PLIL)for the bifunctional electrocatalysis of oxygen evolution reaction(OER)and furfural oxidation reaction(FOR),*** oxidation of NF surface to NiO and deposition of CoO and/or Cu_(2)O on NF during PLIL offer distinct advantages for enhancing both the OER and ***/NiO/NF electrocatalyst provides a consistently low overpotential of~359 m V(OER)at 10 m A/cm^(2),achieving the maximum FA yield(~16.37 m M)with 61.5%selectivity,79.5%carbon balance,and a remarkable Faradaic efficiency of~90.1%during 2 h of FOR at 1.43 V(*** hydrogen electrode).Mechanistic pathway via in situ electrochemical-Raman spectroscopy on CoO/NiO/NF reveals the involvement of phase transition intermediates(NiOOH and CoOOH)as surface-active centers during electrochemical *** carbonyl carbon in FF is attacked by hydroxyl groups to form unstable hydrates that subsequently undergo further oxidation to yield FA *** method holds promise for large-scale applications,enabling simultaneous production of renewable building materials and fuel.

关键词： Pulsed laser irradiation in liquids Water and furfural oxidation In situ Raman spectroscopy CoO/NiO/nickel foam Cu_(2)O/Nio/nickel foam 2-furoic acid