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Large Brunner's gland adenoma:Case report and literature review

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World Journal of Gastroenterology 2006年第12期12卷 1966-1968页

作者： Alba Rocco PasqualeBorriello debora Compare Patrizia DeColibus LoredanaPica GerardoNardone Alessandro Iacono Department University"Federico Ⅱ" NaplesItaly

Brunner＇s gland adenoma （BGA） is a very rare benign tumour of the duodenum, which is usually asymptomatic and discovered incidentally at endoscopy. Occasionally, this lesion may be large, causing upper gastrointestinal haemorrhage or intestinal obstruction. The case had a large Brunner＇s gland adenoma, presenting melena that was managed by endoscopic excision.

关键词： Brunner's gland adenoma Endoscopic resection Giant brunneroma

Is Renewable Energy Policy in Cameroon Inclusive?

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Is Renewable Energy Policy in Cameroon Inclusive?

作者： MBENG Elisabeth Reine debora 西南大学

学位级别：硕士

由于可再生能源对环境的积极影响以及作为应对气候变化的工具,如今可再生能源正成为主要的能源来源,一些国家正在制定法律和政策利用可再生能源。在可再生能源方面,非洲国家可能不如欧洲国家先进,但我们可以看到可再生能源项目,尤其是... 详细信息

由于可再生能源对环境的积极影响以及作为应对气候变化的工具,如今可再生能源正成为主要的能源来源,一些国家正在制定法律和政策利用可再生能源。在可再生能源方面,非洲国家可能不如欧洲国家先进,但我们可以看到可再生能源项目,尤其是太阳能光伏和小水电项目取得了长足的进步。喀麦隆是愿意采用可再生能源项目并制定法律和政策以加快实施的撒哈拉以南非洲国家之一。喀麦隆的所有可再生能源项目主要遵循2011年12月14日第2011/022号电力部门的法律。但在2020年,我们看到了国家发展战略(NDS)30的实施,我们可以意识到可再生能源也上线了,可能没有预期的那么多,但至少这是一个迹象,喀麦隆政府(Go C)牢记可再生能源的重要性。在NDS-30中,可以看出可再生能源项目不仅涉及能源/电力部门,还涉及交通、健康等其他部门。因此,包括所有这些其他部门可以帮助促进经济、建设和促进为国家发展提供可持续的环境。我们的工作是突出喀麦隆不同部门的可再生能源项目,确定可再生能源政策是否具有足够的包容性以建立一个可持续发展的国家,或者所有实施的可再生能源项目是否都根据电力法进行。如今,可再生能源正在成为趋势,或者实际上是讨论能源和未来能源的主要话题,这是因为可再生能源在清洁电气化和应对气候变化方面发挥着重要作用。实施更多项目,如水力发电厂、太阳能发电厂、电动汽车甚至绿色城市,被视为通过改善健康、提供绿色就业机会以及更重要地教育人们了解可再生能源的优势和重要性来简化人们生活的手段。喀麦隆愿意通过可再生能源项目促进可再生能源,这就是我们决定专注于已经实施或未来实施的不同可再生能源项目的原因。我们针对几个行业,这些行业被视为国家发展的关键。不同的部门包括教育部门、农业、卫生甚至交通部门。在选定的不同部门中,我们决定提出喀麦隆政府在该特定部门实现可再生能源项目的目标,为什么它很重要以及该项目对整个国家的人口的影响。很容易注意到的是,大多数项目要么处于待命状态,要么即将到位。但同样重要的是要指出每个项目对社区和国家的积极影响。我们还必须展示能源效率所发挥的作用,因为重要的是要显着减少预计用电量,以应对当前和未来在匹配能源需求方面遇到的困难,同时不危及经济增长,同时继续促进电力供应和舒适度增加。我们的工作必须指出能源效率所起的作用,因此我们决定展示喀麦隆可以从有效使用能源中获得的潜在能源节约。我们确定了几个行业,如工业、第三产业、住宅甚至最终用户,而且我们认为展示可再生能源能源效率的宏观经济方面非常重要。这项工作还旨在展示如何标记相互关联的能源消耗和能源效率政策。在论文的最后一章介绍了其他一些非洲国家的能源现状和获取途径,以及非洲向可再生能源的转型在过去十年中取得了怎样的令人印象深刻的进展,许多非洲国家近年来正在努力提高可再生能源产能。总之,我们认为喀麦隆应该在其政策上开展更多工作,并通过按部门制定更多能源政策,而不仅仅是一个处理多个部门的政策框架。我们展示了GOC必须实施更多可再生能源项目的意愿,但我们觉得可以而且应该做更多的事情,但我们对取得的进展表示赞赏。此外,建议建立一个监管框架,允许发展可能促进向能源密集度较低的经济过渡的某些专业和活动。

关键词：可再生能源政策喀麦隆

Wound-Induced Shoot-to-Root Relocation of JA-Ile Precursors Coordinates Arabidopsis Growth

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Molecular Plant 2019年第10期12卷 1383-1394页

作者： Adina Schulze Marlene Zimmer Stefan Mielke Hagen Stellmach Charles WMelnyk Bettina Hause debora Gasperini Department of Molecular Signal Processing Leibniz Institute of Plant BiochemistryWeinberg 306120 Halle(Saale)Germany Department of Cell and Metabolic Biology Leibniz Institute of Plant Biochemistry06120 Halle(Saale)Germany Department of Plant Biology.Swedish University of Agricultural Sciences 75651 UppsalaSweden

Multicellular organisms rely on the movement of signaling molecules across cells,tissues,and organs to communicate among distal *** plants,localized leaf damage activates jasmonic acid(JA)-dependent transcriptional reprogramming in both harmed and unharmed *** it has been indicated that JA species can translocate from damaged into distal sites,the identity of the mobile compound(s),the tissues through which they translocate,and the effect of their relocation remain ***,we found that following shoot wounding,the relocation of endogenous jasmonates through the phloem is essential to initiate JA signaling and stunt growth in unharmed roots of Arabidopsis *** employing grafting experiments and hormone profiling,we uncovered that the hormone precursor cis-12-oxo-phytodienoic acid(OPDA)and its derivatives,but not the bioactive JA-Ile conjugate,translocate from wounded shoots into undamaged *** root relocation,the mobile precursors cooperatively regulated JA responses through their conversion into JA-Ile and JA signaling ***,our findings demonstrate the existence of long-distance translocation of endogenous OPDA and its derivatives,which serve as mobile molecules to coordinate shoot-to-root responses,and highlight the importance of a controlled redistribution of hormone precursors among organs during plant stress acclimation.

关键词： grafting jasmonate OPDA phloem phytohormone

Lilly Reich:The architecture and critique of an invisibilized woman

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Frontiers of Architectural Research 2023年第1期12卷 15-27页

作者： Laura Lizondo-Sevilla debora Domingo-Calabuig Department of Architectural Projects Universitat Politecnica de ValenciaValencia 46022Spain

The architectural modernity that prevailed in Germany during the first half of the twentieth century cannot be understood without an appreciation of the work of Lilly Reich,a brilliant designer of interiors,furniture,and ephemeral architecture who exerted significant influence from her active position as a member of the Deutscher *** the critical recognition she acquired in the media of the time during her solo career,her association with the architect Mies van der Rohe,far from positioning her in the field of contributions,relegated her to the role of a mere *** this reason,this article aims to shed light on the extensive legacy of Lilly Reich,a woman whose figure is being acknowledged as a result of recent research but who was nevertheless omitted from the leading books on the history of *** methodology employed in the research analyses comparatively“what she did”and“what was said about her”,highlighting the convergences and divergences between“work”and“criticism”.The study and its results yield interesting conclusions regarding both the recognition that Lilly Reich received during her lifetime and the criticism she received after her death and up to the present day.

关键词： Lilly Reich Architecture Design Critique Invisibilization Woman

Polyphenols isolated from Acacia mearnsii bark with anti-inflammatory and carbolytic enzyme inhibitory activities

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Chinese Journal of Natural Medicines 2017年第11期15卷 816-824页

作者： XIONG Jia GRACE Mary H ESPOSITO debora KOMARNYTSKY Slavko WANG Fei LILA Mary Ann Department of Chemical Engineering Jiangsu Key Lab of Biomass-based Green Fuels and Chemicals Nanjing Forestry University Plants for Human Health Institute Department of Food Bioprocessing and Nutrition Sciences North Carolina State UniversityNorth Carolina Research Campus

The present study was designed to characterize the polyphenols isolated from Acacia mearnsii bark crude extract(B) and fractions(B1-B7) obtained by high-speed counter-current chromatography(HSCCC) and evaluate their anti-inflammatory and carbolytic enzymes(α-glucosidase and α-amylase) inhibitory activities. Fractions B4, B5, B6, B7(total phenolics 850.3, 983.0, 843.9, and 572.5 mg·g^(-1)), respectively; proanthocyanidins 75.7, 90.5, 95.0, and 44.8 mg·g^(-1)), respectively) showed significant activities against reactive oxygen species(ROS), nitric oxide(NO) production, and expression of pro-inflammatory genes interleukin-1β(IL-1β) and inducible nitric oxide synthase(iNOS) in a lipopolysaccharide(LPS)-stimulated mouse macrophage cell line RAW 264.7. All the extracts suppressed α-glucosidase and α-amylase activities, two primary enzymes responsible for carbohydrate digestion. A. mearnsii bark samples possessed significantly stronger inhibitory effects against α-glucosidase enzyme(IC_(50) of 0.4-1.4 μg·mL^(-1)) than the pharmaceutical acarbose(IC_(50) 141.8 μg·mL^(-1))). B6 and B7(IC_(50) 17.6 and 11.7 μg·mL^(-1), respectively) exhibited α-amylase inhibitory activity as efficacious as acarbose(IC_(50) 15.4 μg·mL^(-1))). Moreover, B extract, at 25 μg·mL^(-1), significantly decreased the non-mitochondrial oxidative burst that is often associated with inflammatory response in human monocytic macrophages.

关键词： acacia mearnsii Proanthocyanidins Anti-inflammatory α-Amylase α-Glucosidase

Neural Correlates of Human Associative Learning

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Tsinghua Science and Technology 2011年第2期16卷 140-144页

作者： Andreas Marschner Raffael Kalisch Bram Vervliet debora Vansteenwegen Christian Büchel NeuroImage Nord Department of Systems NeuroscienceUniversity Medical Center Hamburg-Eppendorf Department of Psychology Katholieke Universiteit Leuven

Lesion studies in animals have associated the amygdala mainly with aversive conditioning, both cued and contextual. However, neurophysiological studies indicate that the amygdala has a role in the processing of positive emotions in some kinds of stimulus-reward learning. The aim of the current study was to extend these findings to humans. Functional magnetic resonance imaging was applied to investigate the neural basis of aversive and appetitive conditioning. In the first study, aversive electrical shocks were deliv- ered as either cue or context related. The second study integrated appetitive and aversive conditioning us- ing electric shocks as aversive and monetary rewards as appetitive reinforcers. Differential responses in the amygdala were observed during both cue and contextual conditioning, whereas context conditioning additionally recruited the hippocampus. Amygdala activity was higher for reinforced acoustic stimuli. The findings underline the importance of the amygdala in associative learning, irrespective of the stimulus valence and stimulus type.

关键词： amygdale conditioning valence

Pre-endoscopic screening for Helicobacter pylori and celiac disease in young anemic women

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World Journal of Gastroenterology 2009年第22期15卷 2748-2753页

作者： Lucy Vannella debora Gianni Edith Lahner Antonio Amato Enzo Grossi Gianfranco Delle Fave Bruno Annibale Department of Digestive and Liver Disease Hospital Sant'AndreaII School of Medicine University Sapienza Center for Thalassemic Disease of Rome Department of Medical Affair Italian Diagnostic Center Department of Digestive and Liver Disease Hospital Sant’AndreaII School of Medicine University Sapienza

AIM： To evaluate the usefulness of pre-endoscopic serological screening for He//cobacter py/or/ （H py/or/} infection and celiac disease in women aged 〈 50 years affected by iron-deficiency anemia （IDA）. METHODS： One hundred and fifteen women aged 〈 50 years with IDA were tested by human recombinant tissue transglutaminase IgA antibodies （tTG） and anti-H pylori IgG antibodies, tTG and H pylori IgG antibody were assessed using an enzyme-linked immunosorbent assay （ELISA）. All women were invited to undergo upper GI endoscopy. During gastroscopy, biopsies were collected from antrum （n = 3）, gastric body （n = 3） and duodenum （n = 4） in all patients, irrespective of test results. The assessment of gastritis was performed according to the Sydney system and celiac disease was classified by Marsh＇s System. RESULTS： 45.2% women were test-positive： 41 patients positive for H pylori antibodies, 9 patients for tTG and 2 patients for both. The gastroscopy compliance rate of test-positive women was significantly increased with respect to those test- negative （65.4% vs 42.8%; Fisher test P = 0.0239）. The serological results were confirmed by gastroscopy in 100% of those with positive H pylori antibodies, in 50% of those with positive tTG and in 81.5% of test- negative patient. Sensitivity and specificity were 84.8% and 100%, respectively for Hpylori infection and, 80% and 92.8% for tTG. Twenty-eight patients had positive H pylori antibodies and in all the patients, an active Hpylori infection was found. In particular, in 23 out of 28 （82%） patients with positive H pylori antibodies, a likely cause of IDA was found because of the active inflammation involving the gastric body. CONCLUSION： Anti-H pylori IgG antibody and tTG IgA antibody testing is able to select women with IDA to submit for gastroscopy to identify H pylori pangastritis and/or celiac disease, likely causes of IDA.

关键词： Iron deficiency anemia Women Celiac disease Helicobacter pylori gastritis

Lack of functional link in the tadpole morphology induced by predators

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Current Zoology 2016年第3期62卷 227-235页

作者： Maria Gabriela PEROTTI Mariana PUETA Fabian Gaston JARA Carmen Adria UBED debora Lina MORENO AZOCAR Laboratorio de Fotobiologfa INIBIOMA CONICET-Universidad Nacional del Comahue O.uintral 1250 Bariloche Rio Negro Argentina Departamento de Biologfa General. Universidad Nacional del Comahue Quintral 1250 Bariloche Rio Negro Argentina Departamento de Zoologia INIBIOMA CONICET-Universidad Nacional del Comahue Quintral 1250 8400 Bariloche Rio Negro Argentina

Most studies of predator-induced plasticity have focused on documenting how prey species re- spond to predators by modifying phenotypic traits and how traits correlate with fitness. We have previously shown that Pleurodema thaul tadpoles exposed to the dragonfly Rhionaeschna varie- gata responded strongly by showing morphological changes, less activity, and better survival than non-exposed tadpoles. Here, we tested whether there is a functional link between morphological plasticity and increased survival in the presence of predators. Tadpoles that experienced predation risk were smaller, less developed, and much less active than tadpoles without this experience. Burst speed did not correlate significantly with morphological changes and predator-induced deeper tails did not act as a lure to divert predator strikes away from the head. Although we have previously found that tadpoles with predator-induced morphology survive better under a direct predator threat, our results on the functional link between morphology and fitness are not conclu- sive. Our results suggest that in P. thaultadpoles （1） burst speed is not important to evade preda- tors, （2） those exposed to predators reduce their activity, and （3） morphological changes do not divert predator attacks away from areas that compromise tadpole survivalEE. Our results show that morphological changes in P. thaul tadpoles do not explain burst speed or lure attraction, al- though there was a clear reduction of activity, which itself reduces predation. We propose that changes in tadpole activity could be further analyzed from another perspective, with morphological change as an indirect product of behavior mediated by physiological mechanisms.

关键词： induced morphology lure effect predator exposure swimming performance tadpoles.

Neurodevelopmental disorders:An innovative perspective via the response to intervention model

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World Journal of Psychiatry 2021年第11期11卷 1017-1026页

作者： Celestino Rodríguez debora Areces Trinidad García Marisol Cueli Paloma Gonzalez-Castro Department of Psychology University of OviedoOviedo 33003AsturiasSpain

Neurodevelopmental disorders are a group of conditions classified together by the most recent edition of the Diagnostic and Statistical Manual of Mental Disorders which include intellectual disability,communication disorders,autism spectrum disorder,attention-deficit/hyperactivity disorder,specific learning disorder(SLD),and motor *** is present in many students,who exhibit significant difficulties in the acquisition of reading,written expression,and mathematics,mostly due to problems with executive functions(EF).The present study is a review of the current situation of neurodevelopmental disorders and SLD focusing on the benefits of the response to intervention model(RtI),which allows the combination of evaluation and intervention *** also addresses the key role of *** importance of adapting RtI to new possibilities such as the use of virtual reality is discussed and a theoretical framework for carrying that out is provided.

关键词： Neurodevelopmental disorders Specific learning disorder Response to intervention model Virtual reality