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Carbon nanotubes:Evaluation of toxicity at biointerfaces

Journal of Pharmaceutical Analysis 2019年第5期9卷 293-300页

作者： debashish Mohanta Soma Patnaik Sanchit Sood Nilanjan das Department of Biotechnology Manav Rachna International Institute of Research Studies Faridabad Haryana India Accendere KMS New Delhi India

Carbon nanotubes (CNTs) are a class of carbon allotropes with interesting properties that make them productive materials for usage in various disciplines of nanotechnology such as in electronics equipments, optics and therapeutics. They exhibit distinguished properties viz., strength, and high electrical and heat conductivity. Their uniqueness can be attributed due to the bonding pattern present between the atoms which are very strong and also exhibit high extreme aspect ratios. CNTs are classified as singlewalled carbon nanotubes (SWCNTs) and multi-walled carbon nanotubes (MWCNTs) on the basis of number of sidewalls present and the way they are arranged spatially. Application of CNTs to improve the performance of many products, especially in healthcare, has led to an occupational and public exposure to these nanomaterials. Hence, it becomes a major concern to analyze the issues pertaining to the toxicity of CNTs and find the best suitable ways to counter those challenges. This review summarizes the toxicity issues of CNTs in vitro and in vivo in different organ systems (bio interphases) of the body that result in cellular toxicity.

关键词： Bio interphases Carbon nanotubes (CNTs) In vivo toxicity In vitro toxicity

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Importance of Wolbachia-mediated biocontrol to reduce dengue in Bangladesh and other dengue-endemic developing countries

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Biosafety and Health 2023年第2期5卷 69-77页

作者： Abdullah Al Noman Debashish Das Zinnatun Nesa Md.Tariquzzaman Fariha Sharzana Md.Rakibul Hasan Baizid Khoorshid Riaz Golam Sharower Mohammad Meshbahur Rahman Department of Genetic Engineering&Biotechnology Jashore University of Science and TechnologyJashore 7408Bangladesh Directorate General of Health Services Government of the People's Republic of Bangladesh Ministry of Health and Family WelfareDhaka 1212Bangladesh Center for Medical Biotechnology Government of the People's Republic of Bangladesh Ministry of Health and Family WelfareDhaka 1212Bangladesh Department of Public Health and Hospital Administration National Institute of Preventive and Social Medicine(NIPSOM)Dhaka 1212Bangladesh Department of Entomology National Institute of Preventive and Social Medicine(NIPSOM)Dhaka 1212Bangladesh Department of Biostatistics National Institute of Preventive and Social Medicine(NIPSOM)Dhaka 1212Bangladesh

Mosquito-borne diseases,particularly dengue and chikungunya have become global threats,infecting millions of people worldwide,including developing countries of Southeast Asia and Latin America.Bangladesh,like many other developing countries,is experiencing frequent dengue outbreaks.This article,therefore,critically discussed the current status of dengue disease,vector control approaches,and the need for Wolbachia-mediated intervention in Bangladesh and other dengue-endemic developing countries.In this narrative review study,rel-evant literature was searched from major databases and search engines such as PubMed,BanglaJol,World Health Organization(WHO)/European Centre for Disease Prevention and Control(ECDC)and Google Scholar.Considering the selection criteria,our search strategies finally involved 55 related literature for further investigation.Findings showed that current vector control strategies could not render protection for an extended period,and the disease burden of arboviruses is increasing.The impoverished outbreak preparedness,urbanization,climate change,and less efficacy of existing control methods have made people susceptible to vector-borne diseases.Hence,Wolbachia,a naturally occurring endosymbiont of many mosquito species that can potentially limit virus transmission through several host genetic alterations,would be a potential alterna-tive for dengue prevention.We also critically discussed the challenges and prospects of Wolbachia-based den-gue control in developing countries.The evidence supporting the efficacy and safety of this intervention and its mechanism have also been elucidated.Empirical evidence suggests that this introgression method could be an eco-friendly and long-lasting dengue control method.This review would help the policymakers and health experts devise a scheme of Wolbachia-based dengue control that can control mosquito-borne diseases,partic-ularly dengue in Bangladesh and other developing countries.

关键词： Wolbachia-based biocontrol Mosquitoes-borne diseases Dengue Biological control Developing countries

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Industry 4.0 Application in Manufacturing for Real-Time Monitoring and Control

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Journal of Dynamics, Monitoring and Diagnostics 2022年第3期1卷 176-187页

作者： Debasish Mishra Ashok Priyadarshi Sarthak M das Sristi Shree Abhinav Gupta Surjya K Pal debashish Chakravarty Advanced Technology Development Centre Indian Institute of Technology KharagpurKharagpurWest Bengal 721302India Mathematics and Computing Birla Institute of Technology MesraRanchiJharkhand 835215India Information Technology Birla Institute of Technology MesraRanchiJharkhand 835215India Computer Science and Engineering Birla Institute of Technology MesraRanchiJharkhand 835215India Electronics and Communication Engineering Birla Institute of Technology MesraRanchiJharkhand 835215India Department of Mechanical Engineering Indian Institute of Technology KharagpurKharagpurWest Bengal 721302India Department of Mining Engineering Indian Institute of Technology KharagpurKharagpurWest Bengal 721302India

Modern manufacturing aims to reduce downtime and track process anomalies to make profitable business decisions.This ideology is strengthened by Industry 4.0,which aims to continuously monitor high-value manufacturing assets.This article builds upon the Industry 4.0 concept to improve the efficiency of manufacturing systems.The major contribution is a framework for continuous monitoring and feedback-based control in the friction stir welding(FSW)process.It consists of a CNC manufacturing machine,sensors,edge,cloud systems,and deep neural networks,all working cohesively in real time.The edge device,located near the FSW machine,consists of a neural network that receives sensory information and predicts weld quality in real time.It addresses time-critical manufacturing decisions.Cloud receives the sensory data if weld quality is poor,and a second neural network predicts the new set of welding parameters that are sent as feedback to the welding machine.Several experiments are conducted for training the neural networks.The framework successfully tracks process quality and improves the welding by controlling it in real time.The system enables faster monitoring and control achieved in less than 1 s.The framework is validated through several experiments.

关键词： cloud edge deep neural networks friction stir welding Industry 4.0 internet of things machine learning manufacturing process control process monitoring signal processing

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印度非接触镜佩带者的棘阿米巴角膜炎：DNA分型的确认与一种简便的检测分析法

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美国医学会眼科杂志（中文版） 2005年第3期17卷 182-182页

作者： Savitri Sharma Gunisha Pasricha debashish das Ramesh K. Aggarwal 冯云（译）雷嘉启（校）

目的：为了证实原生动物棘阿米巴是印度人群中非接触镜相关性角膜炎的病原体之一，并开发一种简单而敏感的诊断方法用于临床检测。

关键词：棘阿米巴角膜炎印度人群接触镜 DNA分型检测分析佩带原生动物临床检测诊断方法

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