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ODD-EVEN EFFECT OF LYOTROPIC LIQUID CRYSTALLINE PROPERTIES OF AROMATIC-ALIPHATIC COPOLYAMIdeS

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Chinese Journal of Polymer Science 2001年第1期19卷 103-106页

作者： Xiao-zhong Lu Yan-qing Lian Xiao-gong Wang Qi-xiang Zhou de-shan Liu department of Chemical Engineering and School of Materials Science and Engineering Tsinghua UniversityBeijing 100084China

A series of aromatic-aliphatic copolyamides containing different aliphatic diamine units was synthesized by low temperature solution *** liquid crystalline critical concentration(c^(*))and liquid crystalline critical temperature(T^(*))of these copolyamides exhibited an odd-even zigzag effect with the odd-even variation of carbon atom number in the aliphatic diamines used.

关键词： odd-even effect copolyamide lyotropic phase transition

About the Observed Asymmetry between Matter and Antimatter

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Journal of Modern Physics 2022年第7期13卷 1099-1116页

作者： Luis Grave de Peralta department of Physics and Astronomy Texas Tech University Lubbock TX USA Nano Tech Center Texas Tech University Lubbock TX USA

Some consequences, due to the existence of a pair of decoupled Schrödinger-like but relativistic quantum mechanics wave equations, are explored. It is shown that one equation directly describes the quantum states of a single spin-0 particle, and the other one indirectly describes the quantum states of the corresponding antiparticle. In correspondence with the matter-antimatter symmetry, for a Coulomb potential, a charge conjugation operation transforms the second equation in the first one. However, if a particle could interact with itself (gravitationally or electrically) due to the spread of its wavefunction, the C-symmetry could be broken;therefore, matter and antimatter could be distinguished. Under these assumptions, it is deducted the impossibility of the existence of particles and antiparticles with a mass larger than the Plank mass (mP), or with the absolute value of the charge larger than the Plank charge (qP). It is proposed the existence of primordial antimatter electrical sinks. It is also suggested that all macroscopic matter objects with a mass m > mP, and all macroscopic antimatter bodies with a charge |q| > qP should not be quantum but classical objects. It is argued that these findings could explain the absence of antimatter with a complicated structure and partially explain the excess of charged matter in the known Universe.

关键词： Relativistic Quantum Mechanics Antimatter Primordial Black Holes

Dysregulation of the PD-1/PD-L1 pathway contributes to the pathogenesis of celiac disease

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Cellular & Molecular Immunology 2019年第9期16卷 777-779页

作者： Candelaria Ponce de Leon Miguel Angel Lopez-Casado Pedro Lorite Teresa Palomeque Maria Isabel Torres department of Experimental Biology University of JaenJaenSpain department of Pediatrics Gastroenterology Hospital Virgen de las NievesGranadaSpain

In this study,we focus on the alteration of the programmed cell death 1(PD-1)/PD-L1 pathway in celiac *** discuss the diverse roles of the PD-1 pathway in regulating immune responses and how this knowledge can improve celiac disease(CD)*** PD-1 and PD-L1 levels in the serum and in intestinal biopsies of CD patients may be relevant to the determination of a possible correlation between markers of the autoimmune response,inflammation,and disease activity.

关键词： celiac pathogenesis inflammation

SYNTHESIS AND PHOTOLUMINESCENCE OF AN ANTHRACENE-CONTAINING HYPERBRANCHED POLY(ARYLENEETHYNYLENE)

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Chinese Journal of Polymer Science 2005年第6期23卷 665-669页

作者： Yong-qiang Dong Zhen Li Jacky W. Y. Lam Yu-ping Dong Xin-de Feng Ben-zhong Tang department of Polymer Science and Engineering College of Chemistry and Molecular Engineering Peking University Beijing 100871 China department of Chemistry Center for Display Research The Hong Kong University of Science ＆ Technology Clear Water Bay Kowloon Hong Kong China

A hyperbranched poly（aryleneethynylene） containing anthracene chromophore was synthesized by palladiumcatalyzed cross-coupling reaction of 2,4,6-triiodophenyl 9-anthracenylcarboxylate with 9,9-bis[4-（2-propynyloxy）phenyl]- 9H-fluorene. The structure and properties of the polymer are characterized and evaluated by NMR, IR, UV, PL and TGA analyses. The polymer is soluble in common organic solvents, possesses high thermal stability （Td 〉 330℃）, and emits a strong blue light of 465 nm in both solution and solid states.

关键词： Hyperbranched polymer Cross-coupling Blue light emission

New perspectives in prognostication of hepatocellular carcinoma:The role and clinical implications of transient receptor potential family genes

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World Journal of Gastrointestinal Oncology 2024年第6期16卷 2862-2864页

作者： Shi-Hao Guan Wen-Jing Hu Xin-Yu Wang Yue-Xia Gu de-Hua Zhou department of Plastic Surgery Qingpu Branch of Zhongshan Hospital Affiliated to Fudan UniversityShanghai 201700China department of Nursing Shanghai Fourth People’s Hospital Affiliated to Tongji University School of MedicineShanghai 200434China department of Thyroid Breast and Vascular SurgeryShanghai Fourth People’s Hospital Affiliated to Tongji University School of MedicineShanghai 200434China department of Gastrointestinal Surgery Shanghai Fourth People’s Hospital Affiliated to Tongji University School of MedicineShanghai 200434China

The study titled“Transient receptor potential-related risk model predicts prognosis of hepatocellular carcinoma patients”is a significant contribution to hepatocellular carcinoma(HCC)research,highlighting the role of transient receptor potential(TRP)family genes in the disease’s progression and *** data from The Cancer Genome Atlas database,it establishes a new risk assessment model,emphasizing the interaction of TRP genes with tumor proliferation pathways,key metabolic reactions like retinol metabolism,and the tumor immune ***,the overexpression of the TRPC1 gene in HCC correlates with poorer patient survival outcomes,suggesting its potential as a prognostic biomarker and a target for personalized therapy,particularly in strategies combining immunotherapy and anti-TRP agents.

关键词： Hepatocellular carcinoma Transient receptor potential channels TRPC1 gene Tumor immune microenvironment Cancer prognosis Bioinformatics in cancer research

A rare case of epiploic appendagitis in a patient affected by ulcerative colitis on vedolizumab therapy

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Gastroenterology Report 2022年第1期10卷 661-664页

作者： Daniela Pugliese Giuseppe Privitera Luigi Larosa Valentin Calvez Diana Broglia Nicoletta de Matthaeis Alessandro Armuzzi CEMAD IBD UNITUnita Operativa Complessa di Medicina Interna e GastroenterologiaDipartimento di Scienze Mediche e ChirurgicheFondazione Policlinico Universitario“A.Gemelli”IRCCSRomeItaly Dipartimento Universitario di Medicina e Chirurgia Traslazionale Universita Cattolica del Sacro CuoreRomeItaly Fondazione Policlinico Universitario A.Gemelli IRCCS UOC di Radiodiagnostica Presidio ColumbusDipartimento di Diagnostica per immaginiRadioterapia Oncologica ed EmatologiaLargo Francesco VitoRomeItaly Universita Cattolica del Sacro Cuore RomeItaly IBD Center IRCCS Humanitas Research HospitalRozzanoMilanItaly department of Biomedical Sciences Humanitas UniversityPieve EmanueleMilanItaly

Introduction Epiploic appendagitis(EA)is an acute inflammation of the pedunculated mesenteric fat attached to the colonic surface,distinguished into two forms:primary EA,seemingly elicited by local ischaemic factors;and secondary EA(SEA),elicited by the inflammation of the adjacent organs,with diverticulitis being the most common trigger[1].Few case series have described the association between SEA and inflammatory bowel disease(IBD);however,information about clinical,laboratory and imaging findings,outcomes,and the impact of IBD-specific therapy were not *** first report the case of a woman affected by ulcerative colitis(UC)who developed a SEA during vedolizumab therapy(Figure 1A).

关键词： inflammation organs acute

Relevance of EGFR gene mutation with pathological features and prognosis in patients with non-small-cell lung carcinoma

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Asian Pacific Journal of Tropical Medicine 2015年第3期8卷 249-252页

作者： Cheng-de Wang Xin-Rong Wang Chao-Yang Wang Yi-Jun Tang Ming-Wen Hao department of Thoracie Surgery Yantai Yuhuangding Hospital affiliated to Medical College of Qingdao University department of Reproductive Medicine.Yantai Yuhuangding Hospital affiliated to Medical College of Qingdao University

Objective:To study the relevance of EGFR gene mutation with pathological features and prognosis in patients with non-small-cell lung ***:A total of 297 patients from July 2009 to May 2013 were chosen as *** gene mutation were detected with fluorescence quantitative *** of EGFR gene mutation with clinical and pathological features was analyzed,and the prognosis of EGFR- mutant-patients and that of EGFR- wide type-patients was ***:In 297 patients.136(45.79%) showed EGFR gene *** gene mutation had no significant relevance with ***,smoking history,family history of cancer and clinical stage(P>0.05);there was significant relevance between EGFR gene mutation and blood type,pathologic types,differentiation and diameter of cancer(Pde type-patients was statistical significance(Pde type-patients.

关键词： Epidermal growth factor receptor Non-small-cell lung carcinoma Fluorescence quantitative PCR Pathological features Prognosis

Epidemiological Characteristics and Spatio-temporal Patterns of Foodborne Diseases in Jinan, Northern China

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Biomedical and Environmental Sciences 2019年第4期32卷 309-313页

作者： YANG Li SUN Yan Bin ZHONG Qing DUAN de Shui LIU Shou Qin ZHANG Ying Jinan Municipal Center for Disease Control and Prevention School of Public Health China Studies CentreUniversity of Sydney School of Public Health/Climate and Health Research Center Shandong University

Foodborne diseases(FBDs) represent a substantial, yet largely preventable, health burden and result in considerable morbidity and mortality in both developed and developing countries[1]. The FBDs Burden Epidemiology Reference Group(FERG)found that the global burden of FBDs is comparable to those of major infectious diseases, such as human immunodeficiency virus infection/acquired immune deficiency syndrome, malaria, and tuberculosis[2].

关键词： Epidemiological Characteristics Foodborne Diseases

Cancer chemotherapy and beyond:Current status,drug candidates,associated risks and progress in targeted therapeutics

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Genes & Diseases 2023年第4期10卷 1367-1401页

作者： Uttpal Anand Abhijit dey Arvind K.Singh Chandel Rupa Sanyal Amarnath Mishra devendra Kumar Pandey Valentina de Falco Arun Upadhyay Ramesh Kandimalla Anupama Chaudhary Jaspreet Kaur Dhanjal Saikat dewanjee Jayalakshmi Vallamkondu José M.Pérez de la Lastra department of Life Sciences Ben-Gurion University of the NegevBeer-Sheva 84105Israel department of Life Sciences Presidency UniversityKolkataWest Bengal 700073India Center for Disease Biology and Integrative Medicine Faculty of MedicineThe University of TokyoTokyo 113-0033Japan department of Botany Bhairab Ganguly College(affiliated to West Bengal State University)KolkataWest Bengal 700056India Faculty of Science and Technology Amity Institute of Forensic SciencesAmity University Uttar PradeshNoida 201313India department of Biotechnology School of Bioengineering and BiosciencesLovely Professional UniversityPhagwaraPunjab 144411India Institute of Endocrinology and Experimental Oncology(IEOS) National Research Council(CNR)Department of Molecular Medicine and Medical Biotechnology(DMMBM)University of Naples Federico IINaples 80131Italy department of Biochemistry School of Life SciencesCentral University of RajasthanBandar SindariKishangarh AjmerRajasthan 305817India CSIR-Indian Institute of Chemical Technology HyderabadTelangana 500007India department of Biochemistry Kakatiya Medical CollegeWarangalTelangana 506007India Orinin-BioSystems LE-52Lotus Road 4CHD CityKarnalHaryana 132001India department of Computational Biology Indraprastha Institute of Information Technology Delhi(IIIT-D)Okhla Industrial EstatePhase IIINew Delhi 110020India Advanced Pharmacognosy Research Laboratory Department of Pharmaceutical TechnologyJadavpur UniversityKolkata 700032India department of Physics National Institute of Technology-WarangalWarangalTelangana 506004India Biotechnology of Macromolecules Research Group Instituto de Productos Naturales y AgrobiologíaIPNA-CSICSan Cristóbal de La Laguna 38206TenerifeSpain

Cancer is an abnormal state of cells where they undergo uncontrolled proliferation and produce aggressive malignancies that causes millions of deaths every *** the new understanding of the molecular mechanism(s)of disease progression,our knowledge about the disease is snowballing,leading to the evolution of many new therapeutic regimes and their successive *** the past few decades,various combinations of therapies have been pro-posed and are presently employed in the treatment of diverse *** drug therapy,immunotherapy,and personalized medicines are now largely being employed,which were not common a few years *** field of cancer discoveries and therapeutics are evolving fast as cancer type-specific biomarkers are progressively being identified and several types of cancers are nowadays undergoing systematic therapies,extending patients’disease-free survival *** growing evidence shows that a systematic and targeted approach could be the future of cancer medicine,chemotherapy remains a largely opted therapeutic option despite its known side effects on the patient’s physical and psychological ***-apeutic agents/pharmaceuticals served a great purpose over the past few decades and have remained the frontline choice for advanced-stage malignancies where surgery and/or radiation therapy cannot be prescribed due to specific *** present report succinctly reviews the existing and contemporary advancements in chemotherapy and assesses the status of the enrolled drugs/pharmaceuticals;it also comprehensively discusses the emerging role of specific/targeted therapeutic strategies that are presently being employed to achieve better clinical success/survival rate in cancer patients.

关键词： Antimicrobial peptides Cancer therapies Clinical trials Combination therapy Immunotherapy Patient survival Personalized medicine Targeted drug delivery