检索结果-南通市图书馆

Oligodendroglial heterogeneity in health,disease,and recovery:deeper insights into myelin dynamics

Neural Regeneration Research 2025年第11期20卷 3179-3192页

作者： Pieter-Jan Serneels Julie D.de Schutter Lies de Groef Lieve Moons Steven Bergmans KU Leuven Leuven Brain InstituteDepartment of BiologyAnimal Physiology and Neurobiology DivisionNeural Circuit Development&Regeneration Research GroupLeuvenBelgium KU Leuven Leuven Brain InstituteDepartment of BiologyAnimal Physiology and Neurobiology DivisionCellular Communication&Neurodegeneration Research GroupLeuvenBelgium

decades of research asserted that the oligodendroglial lineage comprises two cell types:oligodendrocyte precursor cells and ***,recent studies employing single-cell RNA sequencing techniques have uncovered novel cell states,prompting a revision of the existing *** forward,the oligodendroglial lineage should be delineated into five distinct cell states:oligodendrocyte precursor cells,committed oligodendrocyte precursor cells,newly formed oligodendrocytes,myelin-forming oligodendrocytes,and mature *** new classification system enables a deeper understanding of the oligodendroglia in both physiological and pathological *** this uniform terminology will facilitate comparison and integration of data across ***,including the consolidation of findings from various demyelinating models,is essential to better understand the pathogenesis of demyelinating ***,comparing injury models across species with varying regenerative capacities can provide insights that may lead to new therapeutic strategies to overcome remyelination ***,by standardizing terminology and synthesizing data from diverse studies across different animal models,we can enhance our understanding of myelin pathology in central nervous system disorders such as multiple sclerosis,Alzheimer's disease,and amyotrophic lateral sclerosis,all of which involve oligodendroglial and myelin dysfunction.

关键词： animal models demyelination fish mammals multiple sclerosis myelin neurodegeneration oligodendrocytes oligodendroglial lineage remyelination

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Regulation and function of endoplasmic reticulum autophagy in neurodegenerative diseases

引用

Neural Regeneration Research 2025年第1期20卷 6-20页

作者： Xiu-Yun Zhao de-En Xu Ming-Lei Wu Ji-Chuan Liu Zi-Ling Shi Quan-Hong Ma department of Neurology and Clinical Research Center of Neurological Disease the Second Affiliated Hospital of Soochow UniversitySuzhouJiangsu ProvinceChina Institute of Neuroscience&Jiangsu Key Laboratory of Translational Research and Therapy for Neuro-Psycho-Diseases Soochow UniversitySuzhouJiangsu ProvinceChina department of Neurology Jiangnan University Medical CenterWuxiJiangsu ProvinceChina

The endoplasmic reticulum,a key cellular organelle,regulates a wide variety of cellular *** reticulum autophagy,one of the quality control systems of the endoplasmic reticulum,plays a pivotal role in maintaining endoplasmic reticulum homeostasis by controlling endoplasmic reticulum turnover,remodeling,and *** this review,we briefly describe the endoplasmic reticulum quality control system,and subsequently focus on the role of endoplasmic reticulum autophagy,emphasizing the spatial and temporal mechanisms underlying the regulation of endoplasmic reticulum autophagy according to cellular *** also summarize the evidence relating to how defective or abnormal endoplasmic reticulum autophagy contributes to the pathogenesis of neurodegenerative *** summary,this review highlights the mechanisms associated with the regulation of endoplasmic reticulum autophagy and how they influence the pathophysiology of degenerative nerve *** review would help researchers to understand the roles and regulatory mechanisms of endoplasmic reticulum-phagy in neurodegenerative disorders.

关键词： autophagy endoplasmic reticulum endoplasmic reticulum autophagy endoplasmic reticulum quality control system endoplasmic reticulum receptors endoplasmic reticulum-associated degradation neurodegeneration neurodegenerative disease selective autophagy unfolded protein response

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Stochastic optimal control for norovirus transmission dynamics by contaminated food and water

引用

Chinese Physics B 2022年第2期31卷 173-188页

作者： Anwarud din Yongjin Li department of Mathematics Sun Yat-sen UniversityGuangzhou 510275China

Norovirus is one of the most common causes of viral gastroenteritis in the world,causing significant morbidity,deaths,and medical *** this work,we look at stochastic modelling methodologies for norovirus transmission by water,human to human transmission and *** begin,the proposed stochastic model is shown to have a single global positive ***,we demonstrate adequate criteria for the existence of a unique ergodic stationary distribution R0 s>1 by developing a Lyapunov ***,we find sufficient criteria Rsderstanding chronic communicable diseases around the *** approach also focuses on offering a way of generating Lyapunov functions that can be utilized to investigate the stationary distribution of epidemic models with nonlinear stochastic disturbances.

关键词： stochastic norovirus model stochastic transmission stochastic perturbation stochastic stability stochastic optimal control

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Exploring the electromagnetic information of metasurfaces

引用

National Science Review 2020年第12期7卷 1845-1846页

作者： din-Ping Tsai department of Electronic and Information Engineering The Hong Kong Polytechnic University

Metasurfaces,a 2D counterpart of metamaterials,are made of planar subwavelength-scale meta-atoms with designed *** meta-atoms of a metasurface can be used to couple incident waves to free space with controllable amplitudes,phases and polarizations,yielding many novel photonic devices such as optical meta-lenses[1–4].In recent years,with the bloom of information technologies,

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Qualitative behavior of a discrete SIR epidemic model

引用

International Journal of Biomathematics 2016年第6期9卷 225-239页

作者： Qamar din department of MathematicsThe University of Poonch Rawalakot Rawalakot 12350 Pakistan

In this paper, we study the qualitative behavior of a discrete-time epidemic model. More precisely, we investigate equilibrium points, asymptotic stability of both disease^free equilibrium and the endemic equilibrium. Furthermore, by using comparison method, we obtain the global stability of these equilibrium points under certain parametric con- ditions. Some illustrative examples are provided to support our theoretical discussion.

关键词： Discrete epidemic model steady-states local asymptotic stability globalbehavior.

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Moment Redistribution Effect of the Continuous Glass Fiber Reinforced Polymer-Concrete Composite Slabs Based on Static Loading Experiment

引用

Structural Durability & Health Monitoring 2025年第1期19卷 105-123页

作者： Zhao-Jun Zhang Wen-Wei Wang Jing-Shui Zhen Bo-Cheng Li de-Cheng Cai Yang-Yang Du Hui Huang Offshore Oil Engineering Co.Ltd. Tianjin300461China department of Bridge Engineering School of TransportationSoutheast UniversityNanjing211189China

This study aimed to investigate the moment redistribution in continuous glass fiber reinforced polymer(GFRP)-concrete composite slabs caused by concrete cracking and steel bar yielding in the negative bending moment *** experimental bending moment redistribution test was conducted on continuous GFRP-concrete composite slabs,and a calculation method based on the conjugate beam method was *** composite slabs were formed by combining GFRP profiles with a concrete layer and supported on steel beams to create two-span continuous composite slab *** methods,epoxy resin bonding,and stud connection,were used to connect the composite slabs with the steel *** experimental findings showed that the specimen connected with epoxy resin exhibited two moments redistribution phenomena during the loading process:concrete cracking and steel bar yielding at the internal *** contrast,the composite slab connected with steel beams by studs exhibited only one-moment redistribution phenomenon throughout the loading *** the concrete at the internal support cracked,the bending moment decreased in the internal support section and increased in the midspan *** the steel bars yielded,the bending moment further decreased in the internal support section and increased in the mid-span *** GFRP profiles do not experience cracking,there was no significant decrease in the bending moment of the mid-span *** test specimens experienced compressive failure of concrete at the mid-span *** results showed good agreement between the calculated and experimental values of bending moments in the mid-span section and internal support *** proposed model can effectively predict the moment redistribution behavior of continuous GFRP-concrete composite slabs.

关键词： Moment redistribution GFRP-concrete composite slabs bending moment experimental study analysis model

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The Complex Dynamics of Hepatitis B Infected Individuals with Optimal Control

引用

Journal of Systems Science & Complexity 2021年第4期34卷 1301-1323页

作者： din Anwarud LI Yongjin SHAH Murad Ali department of Mathematics Sun Yat-sen UniversityGuangzhou 510275China School of Mathematical Sciences Beiing Normal UniversityBeijing 100875China

This paper proposes various stages of the hepatitis B virus(HBV)besides its transmissibility and nonlinear incidence rate to develop an epidemic *** authors plan the model,and then prove some basic results for the well-posedness in term of boundedness and ***,the authors find the threshold parameter R0,called the basic/effective reproductive number and carry out local sensitive ***,the authors examine stability and hence condition for stability in terms of *** using sensitivity analysis,the authors formulate a control problem in order to eradicate HBV from the population and proved that the control problem actually *** complete characterization of the optimum system was achieved by using the 4th-order Runge-Kutta procedure.

关键词： Hepatitis B epidemic model non-linear incidence normalized sensitivity index numerical simulation optimization theory reproduction number stability analysis

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

ON DAMPING COEFFICIENT DUE TO PHASE TRANSFORMATION

引用

Acta Mechanica Sinica 2003年第3期19卷 204-207页

作者： din-YuHSIEH (DivisionofAppliedMathematicsBrownUniversity USA)(ZhouPei-YuanCenterforAppliedMathematicsTsinghuaUniversityBeijing100084China)

The damping coefficient of capillary waves due to the evaporation-condensation process at the interface of the two phases of a fluid is *** highlight the mechanism of the effect of heat and mass transfer across the interface between regions of liquid and vapor,potential flow of incompressible fluids are *** other mechanisms of damping are *** fascilitate the analysis,the method of multiple-scale is employed in the analysis,even though the problem is linear.

关键词： phase transformation damping coefficient capillary wave

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A NOVEL STOCHASTIC HEPATITIS B VIRUS EPIdeMIC MOdeL WITH SECOND-ORdeR MULTIPLICATIVE α-STABLE NOISE AND REAL DATA

引用

Acta Mathematica Scientia 2024年第2期44卷 752-788页

作者： Anwarud din Yassine SABBAR 吴鹏 department of Mathematics Sun Yat-Sen UniversityGuangzhou510275China MAIS Laboratory MAMCS GroupFST ErrachidiaMoulay Ismail University of MeknesP.O.Box 509Errachidia52000Morocco School of Science Hangzhou Dianzi UniversityHangzhou310018China School of Data Sciences Zhejiang University of Finance and EconomicsHangzhou310018China

This work presents an advanced and detailed analysis of the mechanisms of hepatitis B virus(HBV)propagation in an environment characterized by variability and *** on some biological features of the virus and the assumptions,the corresponding deterministic model is formulated,which takes into consideration the effect of *** deterministic model is extended to a stochastic framework by considering a new form of disturbance which makes it possible to simulate strong and significant *** long-term behaviors of the virus are predicted by using stochastic differential equations with second-order multiplicative α-stable *** developing the assumptions and employing the novel theoretical tools,the threshold parameter responsible for ergodicity(persistence)and extinction is *** theoretical results of the current study are validated by numerical simulations and parameters estimation is also ***,we obtain the following new interesting findings:(a)in each class,the average time depends on the value ofα;(b)the second-order noise has an inverse effect on the spread of the virus;(c)the shapes of population densities at stationary level quickly changes at certain values of α.The last three conclusions can provide a solid research base for further investigation in the field of biological and ecological modeling.

关键词： HBV model nonlinear perturbation probabilistic bifurcation long-run forecast numerical simulation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Studies on batch adsorptive removal of cadmium and nickel from synthetic waste water using silty clay originated from Balochistan-Pakistan

引用

Chinese Journal of Chemical Engineering 2020年第4期28卷 1171-1176页

作者： Abdul Samad Muhammad Imran din Mahmood Ahmed Institute of Chemistry University of the PunjabLahore 54590Pakistan Renacon Pharma Limited Lahore 54600Pakistan

The potentials of silty clay(SC),acquired from Chaman,Balochistan,were investigated as adsorbent for Ni(Ⅱ)and Cd(Ⅱ)removal from contaminated *** influence of different operating factors like dose,pH,temperature,and time of contact was explored,and optimum values were noted under batch adsorption *** study was conducted with varying concentrations of solutions on optimized conditions and different adsorption models i.e.,Langmuir,Freundlich,Temkin and Dubinin-Radushkevich(D-R)isotherm,which were employed to interpret the *** isothermal data of both Ni(Ⅱ)and Cd(Ⅱ)were well fitted to Langmuir isotherm suggesting the formation of monolayer of metal ions on silty *** values of adsorption capacity noted for Ni(Ⅱ)and Cd(Ⅱ)were 3.603 mg·g^-1 and 5.480 mg·g^-1,*** studies affirmed that pseudo second order(PSO)kinetics was being obeyed by the removal of Ni(Ⅱ)and Cd(Ⅱ).Thermodynamic variables like free energy change(ΔG°),enthalpy change(ΔH°)and entropy change(ΔS°)were *** negative value ofΔG°and the positive values ofΔH°andΔS°unfolded that the removal process of both metal ions of by SC was spontaneous,endothermic and feasible.

关键词： Adsorption Kinetics Isotherm Toxicity Silty clay Thermodynamics

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：