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Constructing Donor–Acceptor‑Linked COFs Electrolytes to Regulate Electron density and Accelerate the Li^(+)Migration in Quasi‑Solid‑State Battery

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Nano-Micro Letters 2025年第1期17卷 456-471页

作者： Genfu zhao Hang Ma Conghui Zhang Yongxin Yang Shuyuan Yu Haiye Zhu Yongjiang Sun Hong Guo School of Materials and Energy International Joint Research Center for Advanced Energy Materials of Yunnan ProvinceYunnan UniversityKunming 650091People’s Republic of China Yunnan Yuntianhua Co. LtdR&D CenterKunming 650228People’s Republic of China Southwest United Graduate School Kunming 650091People’s Republic of China

Regulation the electronic density of solid-state electrolyte by donor–acceptor(D–A)system can achieve highly-selective Li^(+)transportation and conduction in solid-state Li metal *** study reports a high-performance solid-state electrolyte thorough D–A-linked covalent organic frameworks(COFs)based on intramolecular charge transfer *** other reported COFbased solid-state electrolyte,the developed concept with D–A-linked COFs not only achieves electronic modulation to promote highly-selective Li^(+)migration and inhibit Li dendrite,but also offers a crucial opportunity to understand the role of electronic density in solid-state Li metal *** introduced strong electronegativity F-based ligand in COF electrolyte results in highlyselective Li^(+)(transference number 0.83),high ionic conductivity(6.7×10^(-4)S cm^(−1)),excellent cyclic ability(1000 h)in Li metal symmetric cell and high-capacity retention in Li/LiFePO_(4)cell(90.8%for 300 cycles at 5C)than substituted C-and N-based *** is ascribed to outstanding D–A interaction between donor porphyrin and acceptor F atoms,which effectively expedites electron transferring from porphyrin to F-based ligand and enhances Li^(+)***,we anticipate that this work creates insight into the strategy for accelerating Li^(+)conduction in high-performance solid-state Li metal batteries through D–A system.

关键词： Electronic modulation engineering Donor-acceptor-linked covalent organic frameworks Quasi-solid-state Li metal battery

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development of naoe-FOAM-SJTU solver based on OpenFOAM for marine hydrodynamics

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Journal of Hydrodynamics 2019年第1期31卷 1-20页

作者： Jian-hua Wang Wei-wen zhao de-cheng Wan Collaborative Innovation Center for Advanced Ship and deep-Sea Exploration School of Naval ArchitectureOcean and Civil EngineeringState Key Laboratory of Ocean EngineeringShanghai Jiao Tong UniversityShanghai 200240China

A CFD solver naoe-FOAM-SJTU (The abbreviation naoe stands for naval architecture and ocean engineering) is developed based on the open source platform OpenFOAM with the purpose of simulating various marine hydrodynamic *** the present paper,self-developed modules,i.e.,wave generation and absorption,6 degrees of freedom motion,mooring system,dynamic overset grid,fluid-structure interaction,unsteady actuator line model,implemented on the open source platform OpenFOAM are introduced to illustrate the development of the marine hydrodynamics CFD ***,extensive simulations of marine hydrodynamic problems using the developed modules are conducted and validated by available experimental *** has been proved that the CFD solver naoe-FOAM-SJTU is suitable and reliable in predicting the complex viscous flow around ship and offshore *** and accuracy need to be focused in the future development of the present CFD solver.

关键词： Marine hydrodynamics fluid-structure interaction overset grid naoe-FOAM-SJTU solver OpenFOAM

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Numerical analysis of coupled sloshing and motion of a cylindrical FPSO in regular waves

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Journal of Hydrodynamics 2024年第3期36卷 457-465页

作者： Wei-wen zhao Xiao-long Yang de-cheng Wan Computational Marine Hydrodynamics Lab(CMHL) School of Naval ArchitectureOcean and Civil EngineeringShanghai Jiao Tong UniversityShanghai200240China Offshore Oil Engineering Co.Ltd. Tianjin300461China

In this paper,the coupled sloshing and motion characteristics of a cylindrical floating production storage offloading(CFPSO)are numerically investigated by means of computational fluid dynamics(CFD)*** simulations are performed using an in-house CFD solver naoe-FOAM-SJTU which is developed based on *** active wave generating-absorbing boundary condition(GABC)is utilized for wave generation and *** stabilized k-omega SST turbulence model are used to avoid excessive eddy viscosity near the free *** with and without partially filled liquid tanks in regular waves with different wave periods are simulated and vertical planar motions such as surge,heave and pitch response amplitude operators(RAOs)are *** due to liquid sloshing and wave loads are extracted and *** free surface motions inside liquid tanks in one wave period presented to explain the motion characteristics.

关键词： Coupled analysis liquid sloshing wave motion cylindrical floating production storage offloading(CFPSO)

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Longitudinal assessment of peripheral organ metabolism and the gut microbiota in an APP/PS1 transgenic mouse model of Alzheimer’s disease

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Neural Regeneration Research 2025年第10期20卷 2982-2997页

作者： Hongli Li Jianhua Huang Di zhao Lemei Zhu Zheyu Zhang Min Yi Weijun Peng department of Integrated Traditional Chinese&Western Medicine The Second Xiangya HospitalCentral South UniversityChangshaHunan ProvinceChina National Clinical Research Center for Metabolic Diseases ChangshaHunan ProvinceChina Hunan Academy of Chinese Medicine ChangshaHunan ProvinceChina Academician Workstation Changsha Medical UniversityChangshaHunan ProvinceChina

Alzheimer’s disease not only affects the brain,but also induces metabolic dysfunction in peripheral organs and alters the gut *** aim of this study was to investigate systemic changes that occur in Alzheimer’s disease,in particular the association between changes in peripheral organ metabolism,changes in gut microbial composition,and Alzheimer’s disease *** do this,we analyzed peripheral organ metabolism and the gut microbiota in amyloid precursor protein-presenilin 1(APP/PS1)transgenic and control mice at 3,6,9,and 12 months of ***-month-old APP/PS1 mice exhibited cognitive impairment,Alzheimer’s disease-related brain changes,distinctive metabolic disturbances in peripheral organs and fecal samples(as detected by untargeted metabolomics sequencing),and substantial changes in gut microbial composition compared with younger APP/PS1 ***,a strong correlation emerged between the gut microbiota and kidney metabolism in APP/PS1 *** findings suggest that alterations in peripheral organ metabolism and the gut microbiota are closely related to Alzheimer’s disease development,indicating potential new directions for therapeutic strategies.

关键词： Alzheimer’s disease APP/PS1 mice brain-kidney axis gut microbiota heart-brain axis liver-brain axis lung-brain axis microbiota-gut-brain axis peripheral organ metabolism spleen-brain axis

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Storage time affects the level and diagnostic efficacy of plasma biomarkers for neurodegenerative diseases

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Neural Regeneration Research 2025年第8期20卷 2373-2381页

作者： Lifang zhao Mingkai Zhang Qimeng Li Xuemin Wang Jie Lu Ying Han Yanning Cai department of Clinical Biobank Xuanwu HospitalCapital Medical UniversityBeijingChina Beijing Geriatric Medical Research Center BeijingChina department of Neurology Xuanwu HospitalCapital Medical UniversityBeijingChina department of Radiology and Nuclear Medicine Xuanwu HospitalCapital Medical UniversityBeijingChina Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics BeijingChina Key Laboratory of Neurodegenerative diseases Ministry of EducationBeijingChina School of Biomedical Engineering Hainan UniversityHaikouHainan ProvinceChina Center of Alzheimer’s Disease Beijing Institute for Brain DisordersBeijingChina National Clinical Research Center for Geriatric Diseases BeijingChina Institute of Biomedical Engineering Shenzhen Bay LaboratoryGaoke Innovation CenterShenzhenGuangdong ProvinceChina department of Neurobiology Xuanwu HospitalCapital Medical UniversityBeijingChina

Several promising plasma biomarker proteins,such as amyloid-β(Aβ),tau,neurofilament light chain,and glial fibrillary acidic protein,are widely used for the diagnosis of neurodegenerative ***,little is known about the long-term stability of these biomarker proteins in plasma samples stored at-80°*** aimed to explore how storage time would affect the diagnostic accuracy of these biomarkers using a large *** samples from 229 cognitively unimpaired individuals,encompassing healthy controls and those experiencing subjective cognitive decline,as well as 99 patients with cognitive impairment,comprising those with mild cognitive impairment and dementia,were acquired from the Sino Longitudinal Study on Cognitive decline *** samples were stored at-80°C for up to 6 years before being used in this *** results showed that plasma levels of Aβ42,Aβ40,neurofilament light chain,and glial fibrillary acidic protein were not significantly correlated with sample storage ***,the level of total tau showed a negative correlation with sample storage ***,in individuals without cognitive impairment,plasma levels of total protein and tau phosphorylated protein threonine 181(p-tau181)also showed a negative correlation with sample storage *** was not observed in individuals with cognitive ***,we speculate that the diagnostic accuracy of plasma p-tau181 and the p-tau181 to total tau ratio may be influenced by sample storage ***,caution is advised when using these plasma biomarkers for the identification of neurodegenerative diseases,such as Alzheimer's ***,in cohort studies,it is important to consider the impact of storage time on the overall results.

关键词： Alzheimer’s disease amyloid-β diagnostic ability glial fibrillary acidic protein neurodegeneration neurofilament light chain plasma biomarkers single molecule array storage time tau

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稻水象甲种群增长规律初探

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生态学报 2002年第10期22卷 1704-1709页

作者：孙富余田春晖赵成德赵文生王小奇辽宁省农业科学院植物保护研究所沈阳110161 中国农业大学植物保护学院北京100094 沈阳农业大学植物保护学院沈阳110161

扣笼接虫观测稻水象甲不同接虫密度所产下代虫量。结果表明 ,稻水象甲种群增长具有明显密度依赖性 ,接虫密度X越大 ,代间增殖倍率 Y2 越低。 X-Y2 关系用 Y2 =1 /( 0 .836 + 0 .4 2 1 X)的双曲线拟合良好。以水稻移栽后稻田成虫密度 N... 详细信息

扣笼接虫观测稻水象甲不同接虫密度所产下代虫量。结果表明 ,稻水象甲种群增长具有明显密度依赖性 ,接虫密度X越大 ,代间增殖倍率 Y2 越低。 X-Y2 关系用 Y2 =1 /( 0 .836 + 0 .4 2 1 X)的双曲线拟合良好。以水稻移栽后稻田成虫密度 N为指标 ,越冬成虫存活率为 S0 ,防治后成虫残存率为 S1,则第 t和 t+ 1年种群密度关系可表述为 :Nt+ 1=S0 S1Nt/( 0 .0 836 + 0 .0 4 2 1 S0 S1Nt)。模型参数值稳定 ,拟合度好 ,模型描述的种群增长规律与稻水象甲侵入辽宁省以来种群增长的实际情况相吻合。用该模型预测辽宁省不同地区稻水象甲的发生趋势其准确率高。

关键词：稻水象甲种群增长规律害虫发生趋势预测综合防治

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Characterization of ultraviolet communication in a mixed aerosol environment

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Optoelectronics Letters 2025年第2期21卷 77-84页

作者： zhao Taifei SUN Yuxin WANG Wuxin ZHANG Haijun PAN Feixiang WU Hao Artificial Intelligence Key Laboratory of Sichuan Province Sichuan University of Science & Engineering Faculty of Automation and Information Engineering Xi'an University of Technology

Wireless ultraviolet (UV) has strong scattering characteristics and can communicate through non-direct *** UV signals are transmitted in the atmosphere,they are affected by the absorption and scattering effects of atmospheric particles and atmospheric turbulence,resulting in attenuation of UV signal energy and reduced reliability of the communication *** paper focuses on the channel model of UV non-direct-view single scattering communication,and simulates and analyzes the communication characteristics of UV light in atmospheric turbulence and mixed aerosol environment under horizontal,vertical and oblique range communication *** results show that at equal relative humidity,the wireless UV non-directive scattering communication performance for vertical communication scenarios is more affected by the mixed aerosol environment and the communication performance is worse.

关键词： Atmospheric turbulence

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Potential role and therapeutic implications of glutathione peroxidase 4 in the treatment of Alzheimer's disease

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Neural Regeneration Research 2025年第3期20卷 613-631页

作者： Yanxin Shen Guimei Zhang Chunxiao Wei Panpan zhao Yongchun Wang Mingxi Li Li Sun department of Neurology and Neuroscience Center The First Hospital of Jilin UniversityJilin UniversityChangchunJilin ProvinceChina Cognitive Impairment Center Department of NeurologyThe First Hospital of Jilin UniversityJilin UniversityChangchunJilin ProvinceChina

Alzheimer's disease is an age-related neurodegenerative disorder with a complex and incompletely understood pathogenesis. despite extensive research, a cure for Alzheimer's disease has not yet been found. Oxidative stress mediates excessive oxidative responses, and its involvement in Alzheimer's disease pathogenesis as a primary or secondary pathological event is widely accepted. As a member of the selenium-containing antioxidant enzyme family, glutathione peroxidase 4 reduces esterified phospholipid hydroperoxides to maintain cellular redox homeostasis. With the discovery of ferroptosis, the central role of glutathione peroxidase 4 in anti-lipid peroxidation in several diseases, including Alzheimer's disease, has received widespread attention. Increasing evidence suggests that glutathione peroxidase 4 expression is inhibited in the Alzheimer's disease brain, resulting in oxidative stress, inflammation, ferroptosis, and apoptosis, which are closely associated with pathological damage in Alzheimer's disease. Several therapeutic approaches, such as small molecule drugs, natural plant products, and non-pharmacological treatments, ameliorate pathological damage and cognitive function in Alzheimer's disease by promoting glutathione peroxidase 4 expression and enhancing glutathione peroxidase 4 activity. Therefore, glutathione peroxidase 4 upregulation may be a promising strategy for the treatment of Alzheimer's disease. This review provides an overview of the gene structure, biological functions, and regulatory mechanisms of glutathione peroxidase 4, a discussion on the important role of glutathione peroxidase 4 in pathological events closely related to Alzheimer's disease, and a summary of the advances in small-molecule drugs, natural plant products, and non-pharmacological therapies targeting glutathione peroxidase 4 for the treatment of Alzheimer's disease. Most prior studies on this subject used animal models, and relevant clinical studies are lacking. Future clinica

关键词： apoptosis ferroptosis inflammation lipid peroxidation natural plant products neurodegenerative disorder neuroprotection oxidative stress small-molecule drugs

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Omega-Liutex method for the interaction among wave, current and fixed vertical cylinder

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Journal of Hydrodynamics 2023年第1期35卷 83-94页

作者： Bo Han Zhi Pan Wei-wen zhao de-cheng Wan Computational Marine Hydrodynamics Lab(CMHL) School of Naval ArchitectureOcean and Civil EngineeringShanghai Jiao Tong UniversityShanghai200240China Wuhan Second Ship design and Research Institute Wuhan430205China

This paper presents a numerical investigation of the interaction among wave,flow and a fixed cylinder using the naoe-FOAM-SJTU solver,which is a viscous solver for hydrodynamics based on *** simulation considers the strong nonlinear interaction among a regular wave,flow,and a single fixed cylinder due to viscosity,which is common in offshore *** study focus on the vortex induced by viscosity and its significant role in hydrodynamic performance computation.A mesh convergence study is conducted prior to the simulation,and a proper set of mesh is *** simultaneous generation of the regular wave and flow is realized using the numerical field boundary,and the wave propagation is *** results of wave elevation and pressures captured by wave gauges and probes around the fixed cylinder are compared with experiment *** structure of vortices is displayed at significant times,and the phenomena of wave elevation and pressure changes around the cylinder are analyzed in detail using the Omega-Liutex identification method.

关键词： Wave-current interaction vortex Omega-Liutex method naoe-FOAM-SJTU solver numerical simulation

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Optimization of Baffled Rectangular and Prismatic Storage Tank Against the Sloshing Phenomenon

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China Ocean Engineering 2020年第5期34卷 664-676页

作者： Hassan SAGHI NING de-zhi CONG Pei-wen zhao Ming department of Civil Engineering Hakim Sabzevari UniversitySabzevar ***Iran State Key Laboratory of Coastal and Offshore Engineering Dalian University of TechnologyDalian 116024China School of Computing Engineering and MathematicsUniversity of Western SydneyPenrithNSW 2751Australia

The fluid motion in partially filled tanks with internal baffles has wide engineering applications. The installation of baffles is expected to reduce the effect of sloshing as well as the consequent environmental damages. In the present study, a series of experimental tests are performed to investigate the sloshing phenomenon in a baffled rectangular storage tank. In addition, the sloshing phenomenon is also modeled by using Open Foam. Based on the experimental and numerical studies, optimization of the geometric parameters of the tank is performed based on some criteria such as tank area, entropy generation, and the horizontal force exerted on the tank area due to the sloshing *** optimization is also carried out based on the entropy generation minimization analysis. It is noted that the optimum baffle height is in the range of h_b/h_w=0.5-0.75 in the present study(where h_b and h_w are the baffle height and water depth, respectively). Based on the results, the optimal design of the tank is achieved with R_A= 0.9-1.0(where R_A=L/W, L and W are the length and width of the tank, respectively). The results also show that the increase of h_b can lead to a decrease of the maximum pressure and horizontal force exerted on the tank. It is also noted that the horizontal force exerted on the tank firstly continues to increase as the sway motion amplitude ***, as the normalized motion amplitude parameter, a/L(The parameter a is the motion amplitude), exceeds0.067, the effect of motion amplitude on the force is not obvious. The same optimization is also performed in the multiple-variable-baffled tank and prismatic storage tank.

关键词： baffled rectangular storage tank experimental tests sloshing phenomenon optimization entropy generation Open Foam

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