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Journal of Modern Power Systems and Clean Energy 2024年第1期12卷 202-212页

作者： Nana Chang Guobing song Zhongxue Chang Yuping Zheng Xingang yang the School of Electrical Engineering Xi’an Jiaotong UniversityXi’anChina State Key Laboratory of Smart Grid Protection and Control NARI Group CorporationNanjingChina Electric Power Research Institute of State Grid Shanghai Electric Power Company ShanghaiChina

The setting work of backup protection using steady-state current is tedious,and mismatches occasionally occur due to the increased proportion of distributed generations(DGs)connected to the power ***,there is a practical need to study a backup protection technology that does not require step-by-step setting and can be adaptively *** paper proposes an action sequence adaptive to fault positions that uses only positive sequence fault component(PSFC)*** the influence of DGs,the unified time dial setting can be obtained by selecting specific *** protection performance is improved by using the adjacent upstream and downstream protections to meet the coordination time interval in the case of metallic faults at the near-and far-ends of the ***,the expression and implementation scheme for inverse-time backup protection(ITBP)based on the unified characteristic equation is *** results show that this scheme can adapt to DG penetration scenarios and can realize the adaptive coordination of multi-level relays.

关键词： Inverse-time backup protection(ITBP) distributed generation(DG) positive sequence fault component(PSFC)voltage unified characteristic equation adaptive coordination

Multi-UAVs Collaborative Path Planning in the Cramped Environment

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IEEE/CAA Journal of Automatica Sinica 2024年第2期11卷 529-538页

作者： Siyuan Feng Linzhi Zeng Jining Liu Yi yang Wenjie song School of Automation Beijing Institute of TechnologyNanjing 210039China Nanjing Research Institute of Electronics Technology Nanjing 210039China Yichang Testing Technique Research Institute Yichang 443003China IEEE

Due to its flexibility and complementarity, the multiUAVs system is well adapted to complex and cramped workspaces, with great application potential in the search and rescue(SAR) and indoor goods delivery fields. However, safe and effective path planning of multiple unmanned aerial vehicles(UAVs)in the cramped environment is always challenging: conflicts with each other are frequent because of high-density flight paths, collision probability increases because of space constraints, and the search space increases significantly, including time scale, 3D scale and model scale. Thus, this paper proposes a hierarchical collaborative planning framework with a conflict avoidance module at the high level and a path generation module at the low level. The enhanced conflict-base search(ECBS) in our framework is improved to handle the conflicts in the global path planning and avoid the occurrence of local deadlock. And both the collision and kinematic models of UAVs are considered to improve path smoothness and flight safety. Moreover, we specifically designed and published the cramped environment test set containing various unique obstacles to evaluating our framework performance thoroughly. Experiments are carried out relying on Rviz, with multiple flight missions: random, opposite, and staggered, which showed that the proposed method can generate smooth cooperative paths without conflict for at least 60 UAVs in a few *** benchmark and source code are released in https://***/inin-xingtian/multi-UAVs-path-planner.

关键词： Collision avoidance conflict resolution multi-unmanned aerial vehicles(UAVs)system path planning

Effect of operational and geometric parameters on the hydrodynamics of a Wurster coater:A CFD-deM study

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Particuology 2024年第2期85卷 62-76页

作者： Yinqiang song Tuo Zhou Ruiqi Bai Man Zhang Hairui yang department of Energy and Power Engineering Tsinghua UniversityBeijing100084China Key Laboratory for Thermal Science and Power Engineering of Ministry of Education Tsinghua UniversityBeijing100084China State Key Laboratory of Power System and Generation Equipment Tsinghua UniversityBeijing100084China

A coupled CFD-deM method was used to study the hydrodynamics of a Wurster ***,the CFD part of the model was validated by the accurate prediction of the pressure drops over a pseudo-2D fluidized bed under various gas *** effect of gas velocity,gap height,tube length and batch volume of the particles on the cycle time and the residence time of the particles was thoroughly *** central jet gas velocity ui was found to speed up the particle cycle but undermine the coating *** gas velocity at the horizontal transport zone u2 was able to promote the horizontal transport of the particles but should not be too high,otherwise,it would obstruct the normal falling back of the particles in the downward *** gap heights would decrease the coating efficiency but tube length had little impact on *** increment of batch volume would commonly abase the cycle time and the working efficiency under a given *** de-fluidization problem arose when the batch volume increased to 550 ***,this problem could be swept out by the optimization of u1 and *** a mixture of different sizes,the coarse particles enjoyed higher coating efficiency and could travel closer to the *** may shield the fine particles from getting enough coating liquids,and thus coarse particles and fine particles were not recommended to get coated in the same batch.

关键词： Numerical simulation CFD-deM Wurster coater Hydrodynamics Cycle time Residence time

Cell fate regulation governed by p53: Friends or reversible foes in cancer therapy

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Cancer Communications 2024年第3期44卷 297-360页

作者： Bin song Ping yang Shuyu Zhang Laboratory of Radiation Medicine West China Second University HospitalSichuan UniversityChengduSichuanP.R.China The Second Affiliated Hospital of Chengdu Medical College China National Nuclear Corporation 416 HospitalChengduSichuanP.R.China Laboratory of Radiation Medicine NHC Key Laboratory of Nuclear Technology Medical TransformationWest China School of Basic Medical Sciences&Forensic MedicineSichuan UniversityChengduSichuanP.R.China

Cancer is a leading cause of death *** therapies aimed at key oncogenic driver mutations in combination with chemotherapy and radiother-apy as well as immunotherapy have benefited cancer patients *** protein p53(TP53),a crucial tumor suppressor gene encoding p53,reg-ulates numerous downstream genes and cellular phenotypes in response to various *** affected genes are involved in diverse processes,includ-ing cell cycle arrest,DNA repair,cellular senescence,metabolic homeostasis,apoptosis,and ***,accumulating recent studies have contin-ued to reveal novel and unexpected functions of p53 in governing the fate of tumors,for example,functions in ferroptosis,immunity,the tumor microenvi-ronment and microbiome *** the possibilities,the evolutionary plasticity of p53 is the most controversial,partially due to the dizzying array of biological functions that have been attributed to different regulatory mechanisms of p53 *** 40 years after its discovery,this key tumor suppressor remains somewhat *** intricate and diverse functions of p53 in reg-ulating cell fate during cancer treatment are only the tip of the iceberg with respect to its equally complicated structural biology,which has been painstak-ingly ***,TP53 mutation is one of the most significant genetic alterations in cancer,contributing to rapid cancer cell growth and tumor ***,we summarized recent advances that implicate altered p53 in modulating the response to various cancer therapies,including chemotherapy,radiotherapy,and ***,we also discussed potential strategies for targeting p53 as a therapeutic option for cancer.

关键词： cancer chemotherapy drug targeting immunotherapy p53 tumor suppressor

Potential application of radiant floor cooling systems for residential buildings in different climate zones

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Building Simulation 2024年第4期17卷 543-560页

作者： Mengying Cui yang song Yudong Mao Kaimin yang Jiying Liu Zhe Tian School of Thermal Engineering Shandong Jianzhu UniversityJinan250101China School of Environmental Science and Engineering Tianjin UniversityTianjin300072China Key Lab of Building Environment and Energy of Tianjin Tianjin UniversityTianjin300072China

A radiant floor cooling system(RFCS)is a high-comfort and low energy consumption system suitable for residential *** floor systems usually work with fresh air,and their operating performance is affected by climatic *** and outdoor environmental disturbances and the system’s control strategy affect the indoor thermal comfort and energy efficiency of the ***,a multi-story residential building model was established in this *** system simulation program was used to study the operation dynamics of three control strategies of the RFCS based on the calibrated ***,the performance of the control strategies in five climate zones in China were compared using multi-criteria decision-making in *** results show that control strategy has a negligible effect on condensation risk,but the thermal comfort and economic performance differ for different control *** adaptability of different control strategies varies in different climate zones based on the consideration of multiple *** performance of the direct-ground cooling source system is better in Hot summer and warm winter *** variable air volume control strategy scores higher in Serve cold and Temperate zones,and the hours exceeding thermal comfort account for less than 3%of the total simulation ***,it is suggested to choose the RFCS control strategy for residential buildings according to the climate zone characteristics,to increase the energy *** results provide a reliable reference for implementing RFCSs in residential buildings.

关键词： control strategy radiant floor cooling system residential building energy efficiency climate zones

Preparation of Manganese Oxide and Its Adsorption Properties

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Journal of Wuhan University of Technology(Materials Science) 2024年第4期39卷 1031-1040页

作者：贺跃王海峰 yang Pan WANG song CHEN Xiaoliang yang Chunyuan 王家伟 School of Materials and Metallurgy Guizhou UniversityGuiyang 550025China Guizhou Provincial Engineering Technology Research Center of Manganese Materials for Batteries Tongren Guizhou 554300China Guizhou Provincial Key Laboratory of Metallurgical Engineering and Energy Saving Guiyang 550025China

The in-situ oxidation of manganese sulfate solution with H2O_(2),sodium hypochlorite,potassium permanganate and oxygen as oxidants was investigated by means of SEM,EDS,XRD,BET and infrared analysis,and the effects of different oxidants on the morphology,phase composition,surface properties and specific surface area of manganese oxides were *** experimental results show that the diameter of manganese oxide particles prepared with H_(2)O_(2)is the smallest,about 50 nm,and the specific surface area is the largest,63.8764 m^(2)/*** has the advantages of abundant surface hydroxyl groups,no introduction of other impurities and large adsorption *** is most suitable to be used as an oxidant for oxidizing manganese sulfate solution to prepare manganese oxide by in-situ *** manganese oxide prepard by H_(2)O_(2)in-situ oxidation method is used as adsorbent to adsorb cobalt and nickel impurities in manganese *** the reaction pH is 6,the reaction time is 30min and the amount of adsorbent is 1.0 g,the adsorption rates of cobalt and nickel impurities in 100ml manganese sulfate solution are 97.59%and 97.67%,*** residual amounts of cobalt and nickel meet the industrial process standard of first-class products(Co,Ni w/%≤0.005)of high-purity manganese sulfate(Hg/t4823-2015)for *** study plays a guiding role in the preparation and regulation of manganese oxide,and provides a new method with high efficiency,purity and adsorbent availability for the preparation of high-purity manganese sulfate solution.

关键词： manganese oxide in situ oxidation adsorbent regulation mechanism physical chemical properties

Surface engineering of 1D nanocatalysts for value-added selective electrooxidation of organic chemicals

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Nano Research 2024年第3期17卷 1327-1336页

作者： Yongping yang Chuhao Liu Tinglu song Mufan Li Zipeng Zhao Beijing Key Laboratory of Construction Tailorable Advanced Functional Materials and Green Applications Experimental Center of Advanced MaterialsSchool of Materials Science and EngineeringBeijing Institute of TechnologyBeijing 100081China Beijing National Laboratory for Molecular Sciences College of Chemistry and Molecular EngineeringPeking UniversityBeijing 100871China

Electrolytic water splitting by renewable energy is a technology with great potential for producing hydrogen(H_(2))without carbon emission,but this technical route is hindered by its huge energy(electricity)cost,which is mainly wasted by the anode oxygen evolution reaction(OER)while the value of the anode product(oxygen)is very *** the high-energy-cost OER with a selective organic compound electrooxidation carried out at a relatively lower potential can reduce the electricity cost while producing value-added ***,H_(2) generation coupled with synthesis of value-added organic compounds faces the challenge of low selectivity and slow generation rate of the anodic ***-dimensional(1D)nanocatalysts with a unique morphology,well-defined active sites,and good electron conductivity have shown excellent performance in many electrocatalytic *** rational design and regulation of 1D nanocatalysts through surface engineering can optimize the adsorption energy of intermediate molecules and improve the selectivity of organic electrooxidation ***,we summarized the recent research progress of 1D nanocatalysts applied in different organic electrooxidation reactions and introduced several different fabrication strategies for surface engineering of 1D ***,we focused on the relationship between surface engineering and the selectivity of organic electrooxidation reaction ***,future challenges and development prospects of 1D nanocatalysts in the coupled system consisting of organic electrooxidation and hydrogen evolution reactions are briefly outlined.

关键词： hydrogen generation organic compound electrooxidation one-dimensional(1D)nanocatalysts surface engineering selectivity

Mn-modified nitrogen-doped Pt-based electrocatalyst for efficient oxygen reduction in aluminum-air batteries

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Nano Research 2024年第8期17卷 7126-7135页

作者： Li Gao yang song Xuebing Xu Chang Li Chaoquan Hu State Key Laboratory of Mesoscience and Engineering Institute of Process EngineeringChinese Academy of SciencesBeijing 100190China Zhongke Nanjing Institute of Green Manufacturing Industry Nanjing 211135China

In this study,a Mn-modified Pt-based catalyst loaded on nitrogen-doped Ketjen black(Mn-Pt/NKB)is prepared using a simple ethylene glycol reduction *** size of Pt nanoparticles(NPs)is effectively controlled by doping with Mn and *** the smallest average particle size of 1.7 nm,Mn-Pt/NKB demonstrates half-wave potentials of 0.890 and 0.688 V in the alkaline and neutral electrolytes,respectively,which are superior to those of commercial platinum on activated carbon(Pt/C).When applied as an air cathode in aluminum-air battery,it exhibits ultra-high power densities of 190(alkaline)and 26.2 mW·cm^(−2)(neutral).Moreover,the voltage remains stable after 5 h of *** practical application performance of the Mn-Pt/NKB catalyst in an aluminum-air battery is better than that of commercial Pt/***,the oxygen reduction reaction(ORR)mechanism on surfaces with different particle sizes is analyzed using density functional *** cracking is the major pathway on the surface of the small particles with lower energy consumption of 0.5 eV,while water molecule cleavage is the major pathway on the surface of the large particles with higher energy consumption of 0.97 *** lower energy consumption of the oxygen cracking pathway further confirms the ORR mechanism for higher activity on small-sized *** study provides a direction for the rational design of Pt-based catalysts for ORR and sheds light on the commercial development of aluminum-air batteries.

关键词： oxygen reduction reaction precious metal catalysts aluminum-air battery density functional theory(DFT)calculations reaction pathway

Bile acids,gut microbiota,and therapeutic insights in hepatocellular carcinoma

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Cancer Biology & Medicine 2024年第2期21卷 144-162页

作者： yang song Harry CH Lau Xiang Zhang Jun Yu Institute of Digestive Disease and department of Medicine and Therapeutics State Key Laboratory of Digestive DiseaseLi Ka Shing Institute of Health SciencesCUHK Shenzhen Research InstituteThe Chinese University of Hong KongHong KongChina department of Gastroenterology Zhongshan Hospital Xiamen UniversityXiamen 361004China

Hepatocellular carcinoma(HCC)is a prevalent and aggressive liver *** interplay between bile acids(BAs)and the gut microbiota has emerged as a critical factor in HCC development and *** normal conditions,BA metabolism is tightly regulated through a bidirectional interplay between gut microorganisms and *** gut microbiota plays a critical role in BA metabolism,and BAs are endogenous signaling molecules that help maintain liver and intestinal *** note,dysbiotic changes in the gut microbiota during pathogenesis and cancer development can disrupt BA homeostasis,thereby leading to liver inflammation and fibrosis,and ultimately contributing to HCC ***,understanding the intricate interplay between BAs and the gut microbiota is crucial for elucidating the mechanisms underlying *** this review,we comprehensively explore the roles and functions of BA metabolism,with a focus on the interactions between BAs and gut microorganisms in ***,therapeutic strategies targeting BA metabolism and the gut microbiota are discussed,including the use of BA agonists/antagonists,probiotic/prebiotic and dietary interventions,fecal microbiota transplantation,and engineered *** summary,understanding the complex BA-microbiota crosstalk can provide valuable insights into HCC development and facilitate the development of innovative therapeutic approaches for liver malignancy.

关键词： Bile acid gut microbiota hepatocellular carcinoma therapeutics microbiota modulation

Experimental Study on the Effect of Increased Downstroke Duration for an FWAV with Morphing-coupled Wing Flapping Configuration

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Journal of Bionic Engineering 2024年第1期21卷 192-208页

作者： Ang Chen Bifeng song ZhiheWang Kang Liu Dong Xue Xiaojun yang School of Aeronautics Northwestern Polytechnical UniversityXi'an 710072China Harbin Institute of Technology Shenzhen 518055China

This paper is based on a previously developed bio-inspired Flapping Wing Aerial Vehicle(FWAV),RoboFalcon,which can fly with a morphing-coupled flapping *** this paper,a simple flapping stroke control system based on Hall effect sensors is designed and applied,which is capable of assigning different up-and down-stroke speeds for the RoboFalcon platform to achieve an adjustable downstroke *** aerodynamic and power characteristics of the morphing-coupled flapping pattern and the conventional flapping pattern with varying downstroke ratios are measured through a wind tunnel experiment,and the corresponding aerodynamic models are developed and analyzed by the nonlinear least squares *** relatively low power consumption of the slow-downstroke mode of this vehicle is verified through outdoor flight *** results of wind tunnel experiments and flight tests indicate that increased downstroke duration can improve aerodynamic and power performance for the RoboFalcon platform.

关键词： Flapping wing aerial vehicle(FWAV) Downstroke ratio Bio-inspired design Morphing-coupled flapping