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World Journal of Clinical Cases 2021年第33期9卷 10222-10232页

作者： Xue-Lin Pan Zi-Ling Liao Hui Yao Wei-Jie Yan de-ying wen Yan Wang Zhen-Lin Li department of Radiology West China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina department of Thoracic Surgery West China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina

BACKGROUND The clinical role of ground glass opacity(GGO)on computed tomography(CT)in stage I pulmonary adenocarcinoma patients currently remains *** To explore the prognostic value of GGO on CT in lung adenocarcinoma patients who were pathologically diagnosed with tumor-node-metastasis stage *** A comprehensive and systematic search was conducted through the PubMed,EMBASE and Web of Science databases up to April 3,*** hazard ratio(HR)and corresponding 95%confidence interval(CI)were combined to assess the association between the presence of GGO and prognosis,representing overall survival and disease-free *** analysis based on the ratio of GGO was also *** 12.0 software was used for statistical *** A total of 12 studies involving 4467 patients were *** pooled results indicated that the GGO predicted favorable overall survival(HR=0.44,95%CI:0.34-0.59,Pdemonstrated that the proportion of GGO was a good prognostic indicator in pathological stage I pulmonary adenocarcinoma patients,and patients with a higher ratio of GGO showed better prognosis than patients with a lower GGO ratio *** This meta-analysis manifested that the presence of GGO on CT predicted favorable prognosis in tumor-node-metastasis stage I lung *** with a higher GGO ratio were more likely to have a better prognosis than patients with a lower GGO ratio.

关键词： Ground glass opacity Stage I Lung adenocarcinoma Prognosis Metaanalysis

Structural engineering of high-entropy alloys for advanced electrocatalytic reactions

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Tungsten 2025年第1期7卷 1-31页

作者： Qiao Xie ying-Jie Yu Hai-Jun Zhang Ya-Ping deng wen Lei The State Key Laboratory of Refractories and Metallurgy Wuhan University of Science and Technology department of Chemical Engineering Waterloo Institute for Sustainable Energy Waterloo Institute for Nanotechnology University of Waterloo

High-entropy alloys(HEAs) have emerged as promising candidates to replace traditional precious metal catalysts,owing to their unique chemical and physical *** review commences by revisiting the fundamental concepts of HEAs,including their synthesis methods and structural control strategies in *** underscores the critical role of meticulously manipulating both macroscopic and microscopic structures of the HEAs to optimize their catalytic performance.A deep understanding of the structure-activity relationship in HEAs across various configurations is pivotal in developing more effective *** review methodically encapsulates the research progress of structural control strategies for HEAs in achieving efficient energy conversion,with the aim of gaining a better understanding of the relationship between structure and *** review concludes by summarizing the current achievements and challenges,and suggestions for potential future directions of HEAs in the fields of energy conversion and environmental purification.

关键词： Electrocatalytic Energy conversion High-entropy alloys Structural modulation

Broadband and perfect terahertz absorber based on multilayer metamaterial with cross-ring patterned structures

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Optoelectronics Letters 2025年第1期21卷 1-6页

作者： wen Jin LIU Zhanzhi WU Zhengwei PAN Yu ZHANG ying School of Science Xi'an Shiyou University Shaanxi Key Laboratory of Measurement and Control Technology for Oil and Gas Wells

Broadband and perfect terahertz absorber based on multilayer metamaterial using cross-ring patterned structures is proposed and investigated. The structure of the absorber is double absorption layers consisting of a chromium cross ring and eight isosceles right triangles. The unique structure of the double absorbing layers excites the electric dipole multimode resonance, giving rise to high absorption performance. Meanwhile, the influence of construal parameters on absorber behavior is also discussed. The numerical results show that the absorption achieves over 90% ranging from 2.45 THz to 6.25 THz and 99% absorption in the range of 3.7—5.3 THz. The realization of broadband and perfect absorber is described using the impedance matching principle. It is obviously found that the absorber is insensitive to the high angle of incidence for both transverse electric(TE) and transverse magnetic(TM) polarizations. Compared with the former reports, this absorber has remarkable improved absorption efficiency and smaller period. The terahertz absorber may be found applications in the fields of energy capture and thermal detection.

关键词： Metamaterials

deciphering fungal metabolon coupling tandem inverse-electrondemand Diels-Alder reaction and semipinacol rearrangement for the biosynthesis of spiro polycyclic alkaloids

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Science China Chemistry 2025年第1期68卷 288-296页

作者： Shuai Liu wen-Qiang Xu ying-Tong Di Man-Cheng Tang Ding-Kang Chen Ming-Ming Cao Yao-wen Chang Hong-Yu Tang Chun-Mao Yuan Jun-Bo Yang Zhi-Li Zuo Han Guo Zi-Fei Xu ying Zeng Yun-Dong Wu Xiao-Jiang Hao Key Laboratory of Phytochemistry and Natural Medicines (Chinese Academy of Sciences) Kunming Institute of Botany Chinese Academy of Sciences University of Chinese Academy of Sciences Lab of Computational Chemistry and Drug design State Key Laboratory of Chemical Oncogenomics Peking University Shenzhen Graduate School Shenzhen Bay Laboratory State Key Laboratory of Microbial Metabolism School of Life Sciences & Biotechnology Shanghai Jiao Tong University State Key Laboratory of Functions and Applications of Medicinal Plants Guizhou Medical University Molecular Biology Experimental Center Germplasm Bank of Wild Species in Southwest China Kunming Institute of Botany Chinese Academy of Sciences Yunnan Key Laboratory for Wild Plant Resources Kunming Institute of Botany Chinese Academy of Sciences Research Unit of Chemical Biology of Natural Anti-Virus Products Chinese Academy of Medical Sciences

In the intricate process of natural product biosynthesis, a metabolon can enhance metabolic flux by associating sequential enzymes. A fungal metabolon, comprising of flavin-dependent monooxygenase Spe F and P450 monooxygenase Spe G, is identified in the biosynthesis of spiro polycyclic alkaloids(+)-notoamide B and its diastereomer(+)-versicolamide B. Using notoamide E as a substance, Spe F/Spe G metabolon can control the stereoselectivity of its 2,3-epoxidation, followed by hydrogen atom ion at C-17 to generate reactive epoxide tau-m A with dienyl iminium unit. Subsequently,(+)-notoamide B and(+)-versicolamide B are produced via tandem nonenzymatic inverse-electron-demand Diels-Alder reaction and semipinacol rearrangement. This provides the first example of metabolon in the biosynthesis of spiro-prenylated indole alkaloids.

关键词： metabolon Diels-Alder reaction semipinacol rearrangement biosynthesis notoamides spiro polycyclic alkaloids

Cerebral fat embolism following autologous fat injection in facial reconstruction:A case report

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World Journal of Clinical Cases 2025年第2期13卷 50-58页

作者： Xiu-ying Chen Fa Shen Chang Cheng Yu-Han Wang wen-Chao Cheng de-Zhi Yuan wen Huang department of Neurology Chongqing Emergency Medical CenterChongqing University Central HospitalChongqing 400000China department of Neurology Xinqiao HospitalThe Army Medical University(Third Military Medical University)Chongqing 400000China

BACKGROUND Autologous fat injection in facial reconstruction is a common cosmetic *** cerebral fat embolism(CFE)as a complication is rare,it carries serious health *** SUMMARY We present a case of a 29-year-old female patient who developed acute CFE following facial fat filling *** the surgery,the patient experienced symptoms including headache,nausea,vomiting,and difficulty breathing,which was followed by neurological symptoms such as slurred speech and left-sided *** physical examination and auxiliary investigations,including blood tests,head and neck computed tomography angiography,and cranial magnetic resonance diffusion-weighted imaging,were performed upon *** clinical diagnosis was acute cerebral embolism following facial fat filling *** included measures to improve cerebral circulation,dehydration for intracranial pressure reduction,nutritional support,and rehabilitation therapy for left limb *** patient showed a significant improvement in symptoms after 2 weeks of *** recovered left limb muscle strength to grade 5,had clear speech,and experienced complete relief of *** Our case highlights the potential occurrence of severe complications in patients undergoing fat injection in facial *** prevent these complications,plastic surgeons should enhance their professional knowledge and skills.

关键词： Cerebral fat embolism Mechanical thrombectomy Thrombolysis Steroid therapy Symptomatic treatment Case report

增设喷雾降温系统的家用空调器性能与特性的试验研究

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流体机械 2017年第5期45卷 58-61,25页

作者：胡文举张帅李德英张啊文北京建筑大学北京市供热、供燃气、通风及空调重点实验室北京100044 天津大学天津300072

针对家用空调器夏季运行室外热环境差的问题,提出在其室外机增设喷雾加湿装置以降低冷凝温度进而达到提高空调器性能和制冷量的目的。本文对增设喷雾降温系统地空调器进行了试验研究,分析了增设喷雾降温系统对空调器冷凝器出口空气温度... 详细信息

针对家用空调器夏季运行室外热环境差的问题,提出在其室外机增设喷雾加湿装置以降低冷凝温度进而达到提高空调器性能和制冷量的目的。本文对增设喷雾降温系统地空调器进行了试验研究,分析了增设喷雾降温系统对空调器冷凝器出口空气温度和制冷系统性能的影响。实测研究发现,增设喷雾加湿系统后,冷凝器出口制冷剂压力有所降低,制冷系统性能系数EER可提高2%~7%,效果显著。

关键词：喷雾降温冷凝压力性能系数

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Experimental demonstration of 220-GHz terahertz signals wireless transmission over 4.6 km

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Science China(Information Sciences) 2025年第1期68卷 386-388页

作者： Yi WEI Jianjun YU Mingxu WANG Xiongwei YANG Qiutong ZHANG Jingwen TAN Bing ZHANG ying WU Yang HAN Peng TIAN wen ZHOU Kaihui WANG Feng ZHAO State Key Laboratory of ASIC and System Key Laboratory for Information Science of Electromagnetic Waves (MoE)School of Information Science and Technology Fudan University School of Electronic Engineering Xi'an University of Posts and Telecommunications

The advancement of terahertz (THz) communication technology drives the evolution of wireless communication systems,offering novel pathways and technical means for the development of future 6G communication *** wireless communication systems are often constrained by bandwidth limitations of electronic devices in high frequency ***,THz communication technology leverages the characteristics of electromagnetic waves to transcend these limitations,enabling communication athigher frequencies and wider bandwidths.

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Moment Redistribution Effect of the Continuous Glass Fiber Reinforced Polymer-Concrete Composite Slabs Based on Static Loading Experiment

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Structural Durability & Health Monitoring 2025年第1期19卷 105-123页

作者： Zhao-Jun Zhang wen-Wei Wang Jing-Shui Zhen Bo-Cheng Li de-Cheng Cai Yang-Yang Du Hui Huang Offshore Oil Engineering Co.Ltd. Tianjin300461China department of Bridge Engineering School of TransportationSoutheast UniversityNanjing211189China

This study aimed to investigate the moment redistribution in continuous glass fiber reinforced polymer(GFRP)-concrete composite slabs caused by concrete cracking and steel bar yielding in the negative bending moment *** experimental bending moment redistribution test was conducted on continuous GFRP-concrete composite slabs,and a calculation method based on the conjugate beam method was *** composite slabs were formed by combining GFRP profiles with a concrete layer and supported on steel beams to create two-span continuous composite slab *** methods,epoxy resin bonding,and stud connection,were used to connect the composite slabs with the steel *** experimental findings showed that the specimen connected with epoxy resin exhibited two moments redistribution phenomena during the loading process:concrete cracking and steel bar yielding at the internal *** contrast,the composite slab connected with steel beams by studs exhibited only one-moment redistribution phenomenon throughout the loading *** the concrete at the internal support cracked,the bending moment decreased in the internal support section and increased in the midspan *** the steel bars yielded,the bending moment further decreased in the internal support section and increased in the mid-span *** GFRP profiles do not experience cracking,there was no significant decrease in the bending moment of the mid-span *** test specimens experienced compressive failure of concrete at the mid-span *** results showed good agreement between the calculated and experimental values of bending moments in the mid-span section and internal support *** proposed model can effectively predict the moment redistribution behavior of continuous GFRP-concrete composite slabs.

关键词： Moment redistribution GFRP-concrete composite slabs bending moment experimental study analysis model

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无传感器电机位置检测策略综述

微电机 2000年第5期33卷 29-31,34页

作者：谢宝昌任永德刘文瑛上海交通大学上海200030

针对装置直接位置传感器的电机结构复杂、价格昂贵、可靠性低的弱点 ,间接位置传感器技术将成为今后电机控制技术发展的必然趋势。

关键词：无换向器电机磁饱和位置检测无传感器电机

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Targeting TrkB–PSD-95 coupling to mitigate neurological disorders

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Neural Regeneration Research 2025年第3期20卷 715-724页

作者： Xin Yang Yu-wen Alvin Huang John Marshall department of Molecular Biology Cell Biology and BiochemistryBrown UniversityProvidenceRIUSA department of Neurology Warren Alpert Medical School of Brown UniversityProvidenceRIUSA Center for Translational Neuroscience Robert J.and Nancy D.Carney Institute for Brain Science and Brown Institute for Translational ScienceBrown UniversityProvidenceRIUSA

Tropomyosin receptor kinase B(TrkB)signaling plays a pivotal role in dendritic growth and dendritic spine formation to promote learning and *** activity-dependent release of brain-derived neurotrophic factor at synapses binds to pre-or postsynaptic TrkB resulting in the strengthening of synapses,reflected by long-term ***,the association of postsynaptic density protein-95 with TrkB enhances phospholipase Cγ-Ca^(2+)/calmodulin-dependent protein kinaseⅡand phosphatidylinositol 3-kinase-mechanistic target of rapamycin signaling required for long-term *** this review,we discuss TrkB-postsynaptic density protein-95 coupling as a promising strategy to magnify brain-derived neurotrophic factor signaling towards the development of novel therapeutics for specific neurological disorders.A reduction of TrkB signaling has been observed in neurodegenerative disorders,such as Alzheimer's disease and Huntington's disease,and enhancement of postsynaptic density protein-95 association with TrkB signaling could mitigate the observed deficiency of neuronal connectivity in schizophrenia and *** with brain-derived neurotrophic factor is problematic,due to poor pharmacokinetics,low brain penetration,and side effects resulting from activation of the p75 neurotrophin receptor or the truncated TrkB.T1 *** TrkB agonists and antibodies that activate TrkB are being intensively investigated,they cannot distinguish the multiple human TrkB splicing isoforms or cell type-specific *** TrkB–postsynaptic density protein-95 coupling provides an alternative approach to specifically boost TrkB signaling at localized synaptic sites versus global stimulation that risks many adverse side effects.

关键词： Angelman syndrome autism brain-derived neurotrophic factor depression neurodegenerative disorder neurodevelopmental disorder postsynaptic density protein-95 synaptic plasticity TrkB

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