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A　Novel　Thixotropic　Phenomenon——Complex　Thixotropic　Behavior

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Chemical Research in Chinese Universities 1997年第1期13卷 88-90页

作者： HOU Wan guo, SUN de jun, han Shu hua, ZhanG Chun guang and WANG Guo ting (Institute of Colloid and Interface Chemistry, Shandong University , Jinan, 250100) ShanDONG UNIV INST COLLOID & INTERFACES CHEMJINAN 250100PEOPLES R CHINA

ＡＮｏｖｅｌＴｈｉｘｏｔｒｏｐｉｃＰｈｅｎｏｍｅｎｏｎ——ＣｏｍｐｌｅｘＴｈｉｘｏｔｒｏｐｉｃＢｅｈａｖｉｏｒ＊Ｔｏｗｈｏｍｃｏｒｒｅｓｐｏｎｄｅｎｃｅｓｈｏｕｌｄｂｅａｄｄｒｅｓｅｄ．ＨＯＵＷａｎ－ｇｕｏ＊，ＳＵＮ... 详细信息

ＡＮｏｖｅｌＴｈｉｘｏｔｒｏｐｉｃＰｈｅｎｏｍｅｎｏｎ——ＣｏｍｐｌｅｘＴｈｉｘｏｔｒｏｐｉｃＢｅｈａｖｉｏｒ＊Ｔｏｗｈｏｍｃｏｒｒｅｓｐｏｎｄｅｎｃｅｓｈｏｕｌｄｂｅａｄｄｒｅｓｅｄ．ＨＯＵＷａｎ－ｇｕｏ＊，ＳＵＮＤｅ－ｊｕｎ，ＨＡＮＳｈｕ－ｈｕａ...

关键词： Dispersion Thixotropy Aluminum Magnesium Hydroxide Montmorillonite Rheology

A genome-wide association study uncovers that TaPI4K-2A regulates pre-harvest sprouting in wheat

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Plant Communications 2024年第5期5卷 1-4页

作者： Li Tai Jianhui Wu Yexing Jing Huaizeng Liu Qingdong Zeng Xiaojing Xu Shengdixin Shi Hongjin Wang Wenting Liu Jiaqiang Sun de-jun han Kun-Ming Chen National Key Laboratory of Crop Improvement for Stress Tolerance and Production College of Life SciencesNorthwest A&F UniversityYangling 712100ShaanxiP.R.China National Key Laboratory of Crop Improvement for Stress Tolerance and Production College of AgronomyNorthwest A&F UniversityYangling 712100ShaanxiP.R.China State Key Laboratory of Crop Gene Resources and Breeding Institute of Crop SciencesChinese Academy of Agricultural SciencesBeijing 100081P.R.China National Key Laboratory of Crop Improvement for Stress Tolerance and Production College of Plant ProtectionNorthwest A&F UniversityYangling 712100ShaanxiP.R.China

dear Editor,Pre-harvest sprouting(PHS)is a major challenge to cereal crop production in areas with frequent rainfall at harvest time and has significant effects on grain yield and end-use quality(Lang et al.,2021).PHS is quantified by the dormancy/germination ratio of seeds and is largely regulated by two opposing phytohormones,abscisic acid(ABA)and gibberellin(GA)(Tai et al.,2021).ABA induces dormancy and suppresses PHS,whereas GA exerts the opposite effects(Finkelstein et al.,2008).Because of the complexity of the genome,only a few genes involved in regulation of PHS have been identified in wheat,and the underlying molecular regulatory mechanisms of PHS remain largely unknown in this species.

关键词： PHS harvest largely

Multi-active region laser diode with a narrow beam divergence angle

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Optoelectronics Letters 2006年第5期2卷 326-328页

作者： LI Jian-jun SHEN Guang-di CUI BI-feng ZOU de-su han jun deNG jun ing University of Technology Beijing 700022 China

A novel large optical cavity laser diode,which consists of multi-active regions cascaded together through tunnel junctions,is *** growing the epi-layers with LP-MOCVD system on GaAs substrate,the ridge waveguide laser... 详细信息

关键词：激光二极管窄带分散角激光结构

Anomalous quality factor evolution of induced transparency in a virtualized coupled-oscillator system

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 148-155页

作者： Yunhan Yang han Jia Tuo Liu Yuzhen Yang jun Yang Key Laboratory of Noise and Vibration Research Institute of Acoustics Chinese Academy of Sciences University of Chinese Academy of Sciences State Key Laboratory of Acoustics Institute of Acoustics Chinese Academy of Sciences

The phenomenon of induced transparency, characterized by a high quality(Q) factor, holds significant importance in the fields of high-precision sensing, energy storage and wave manipulation. Conventional transparency systems are often constrained by the limited experimentally accessible parameter space and the lack of independent control over intrinsic parameters, thereby hindering advanced research on high-Q effects. Here we propose a virtualized coupled-oscillator system that enables reconfigurable induced transparency in the reflection spectrum. By virtually incorporating a pair of coupled oscillators into an individual acoustic meta-atom, we achieve the manipulation of induced transparency in a decoupled, wide-ranging, and elaborate manner. Exploiting the diverse evolutions across the intrinsic parameter space, we show experimentally a counter-intuitive increase in the Q-factor of the transparency window, which is attributed to the enhanced dissipation of the bright ***, a constant group delay at the center frequency is observed accompanying this evolution. Our work demonstrates an intriguing platform as well as a novel strategy to engineer high-Q induced transparency phenomenon, and paves the way towards applications in programmable acoustic sensors, filters and slow-wave devices.

关键词： induced transparency acoustic meta-atom high quality-factor scattering programmable intrinsic parameter

Mechanistic insight into the synergy between nickel single atoms and nanoparticles on N-doped carbon for electroreduction of CO2

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Journal of Energy Chemistry 2025年第1期100卷 327-336页

作者： Mingdong Sun Wenwen Guan Cailing Chen Chao Wu Xiaoling Liu Biao Meng Tao Chen Yu han jun Wang Shibo Xi Yu Zhou State Key Laboratory of Materials-Oriented Chemical Engineering College of Chemical Engineering Nanjing Tech University Advanced Membranes and Porous Materials Center Physical Sciences and Engineering Division King Abdullah University of Science and Technology Institute of Sustainability for Chemicals Energy and Environment A*STAR (Agency for Science Technology and Research) College of Materials Science and Engineering Sichuan University

The synergy of single atoms （SAs） and nanoparticles （NPs） has demonstrated great potential in promoting the electrocatalytic carbon dioxide reduction reaction （CO2RR）;however,the rationalization of the SAs/NPs proportion remains one challenge for the catalyst ***,a Ni2+-loaded porous poly（ionic liquids）(PIL) precursor synthesized through the free radical self-polymerization of the ionic liquid monomer,1-allyl-3-vinylimidazolium chloride,was pyrolyzed to prepare the Ni,N co-doped carbon materials,in which the proportion of Ni SAs and NPs could be facilely modulated by controlling the annealing *** catalyst Ni-NC-1000 with a moderate proportion of Ni SAs and NPs exhibited high efficiency in the electrocatalytic conversion of CO2into *** Ni K-edge X-ray absorption near-edge structure （XANES） spectra and theoretical calculations were conducted to gain insight into the synergy of Ni SAs and *** charge transfer from Ni NPs to the surrounding carbon layer and then to the Ni SAs resulted in the electron-enriched Ni SAs active *** the electroreduction of CO2,the coexistence of Ni SAs and NPs strengthened the CO2activation and the affinity towards the key intermediate of*COOH,lowering the free energy for the potential-determining*CO2→*COOH step,and therefore promoted the catalysis efficiency.

关键词： Single atom catalyst Synergy effect Carbon catalyst Electrocatalysis

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华丰矿高应力巷道二次支护参数设计研究

煤炭工程 2017年第9期49卷 75-79页

作者：郭东明叶善德王汉军刘波周宝威李军中国矿业大学(北京)力学与建筑工程学院北京100083 深部岩土力学与地下工程国家重点实验室北京100083 北京工业职业技术学院建筑工程系北京100042

为了获得深部高应力巷道围岩二次支护的最佳支护参数,以山东华丰煤矿-1180 m岩石集中巷为研究对象,在原有支护设计的基础上提出优化二次支护参数的方法。依据巷道围岩条件和失稳破坏原因,确定锚索长度和间排距为影响二次支护效果的敏感... 详细信息

为了获得深部高应力巷道围岩二次支护的最佳支护参数,以山东华丰煤矿-1180 m岩石集中巷为研究对象,在原有支护设计的基础上提出优化二次支护参数的方法。依据巷道围岩条件和失稳破坏原因,确定锚索长度和间排距为影响二次支护效果的敏感因素,算出锚索长度和间排距的理论值,并以此推出两者的4个初步设计参数;采用FLAC3D数值软件模拟分析了二次支护16个设计方案的顶板中心下沉量、两帮移近量与底板中心底鼓量。研究结果表明,方案9(锚索长度为8000mm,间排距为1200mm×1200mm)的顶板下沉量为338 mm,两帮移近量为513.8 mm,底鼓量为468.9 mm,围岩变形控制效果好,且经济合理,为最优方案;在实际应用中支护效果也良好。研究结果对确定二次支护参数及改进支护设计具有较好的工程价值。

关键词：二次支护参数正交试验数值模拟巷道围岩

Single-cell omics: experimental workflow, data analyses and applications

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Science China Life Sciences 2025年第1期68卷 5-102页

作者： Fengying Sun Haoyan Li Dongqing Sun Shaliu Fu Lei Gu Xin Shao Qinqin Wang Xin Dong Bin Duan Feiyang Xing jun Wu Minmin Xiao Fangqing Zhao Jing-Dong J.han Qi Liu Xiaohui Fan Chen Li Chenfei Wang Tieliu Shi department of Clinical Laboratory the Affiliated Wuhu Hospital of East China Normal University (The Second People's Hospital of Wuhu City) Pharmaceutical Informatics Institute College of Pharmaceutical SciencesZhejiang University Key Laboratory of Spine and Spinal Cord Injury Repair and Regeneration (Tongji University) Ministry of EducationOrthopaedic DepartmentTongji HospitalBioinformatics DepartmentSchool of Life Sciences and TechnologyTongji University Frontier Science Center for Stem Cells School of Life Sciences and TechnologyTongji University Translational Medical Center for Stem Cell Therapy and Institute for Regenerative Medicine Shanghai East HospitalBioinformatics DepartmentSchool of Life Sciences and TechnologyTongji University Research Institute of Intelligent Computing Zhejiang Lab Shanghai Research Institute for Intelligent Autonomous Systems Center for Single-cell Omics School of Public HealthShanghai Jiao Tong University School of Medicine National Key Laboratory of Chinese Medicine Modernization Innovation Center of Yangtze River DeltaZhejiang University Center for Bioinformatics and Computational Biology Shanghai Key Laboratory of Regulatory Biologythe Institute of Biomedical Sciences and School of Life SciencesEast China Normal University Beijing Institutes of Life Science Chinese Academy of Sciences Peking-Tsinghua Center for Life Sciences Academy for Advanced Interdisciplinary StudiesCenter for Quantitative Biology (CQB)Peking University Zhejiang Key Laboratory of Precision Diagnosis and Therapy for Major Gynecological Diseases Women's HospitalZhejiang University School of Medicine Key Laboratory of Advanced Theory and Application in Statistics and Data Science-MOE School of StatisticsEast China Normal University

Cells are the fundamental units of biological systems and exhibit unique development trajectories and molecular features. Our exploration of how the genomes orchestrate the formation and maintenance of each cell, and control the cellular phenotypes of various organismsis, is both captivating and intricate. Since the inception of the first single-cell RNA technology, technologies related to single-cell sequencing have experienced rapid advancements in recent years. These technologies have expanded horizontally to include single-cell genome, epigenome,proteome, and metabolome, while vertically, they have progressed to integrate multiple omics data and incorporate additional information such as spatial sc RNA-seq and CRISPR screening. Single-cell omics represent a groundbreaking advancement in the biomedical field,offering profound insights into the understanding of complex diseases, including cancers. Here, we comprehensively summarize recent advances in single-cell omics technologies, with a specific focus on the methodology section. This overview aims to guide researchers in selecting appropriate methods for single-cell sequencing and related data analysis.

关键词： single-cell sequencing genome epigenome proteomics metabolomics multimodal spatial transcriptomics CRISPR screening

Recent advances in exploring new blood-based biomarkers for the early diagnosis of gastric cancer

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Science China Chemistry 2025年第1期 35-45页

作者： Xinyu Peng Qian Ma Da han School of Life Science Shanghai University Institute of Molecular Medicine Shanghai Key Laboratory for Nucleic Acid Chemistry and Nanomedicine State Key Laboratory of Oncogenes and Related Genes Renji Hospital School of Medicine Shanghai Jiao Tong University department of Research and development Intellinosis Biotechnologies Co.Ltd.

Gastric cancer(GC) is a prevalent and lethal malignancy worldwide, and the 5-year survival rate is less than 30%. The absence of distinctive symptoms often leads to late-stage diagnosis, contributing to a grim prognosis. Early detection is pivotal for improving the survival rates and outcomes of GC patients. Traditional diagnostic methods, including gastroscopy and histopathological examination, are restricted in the early diagnosis of GC. Conventional protein biomarkers, such as carcinoembryonic antigen(CEA), carbohydrate antigen 19-9(CA19-9), and carbohydrate antigen 72-4(CA72-4), exhibit insufficient sensitivity and specificity for GC screening, which diminishes their clinical value. Recently, novel circulating biomarkers, such as circulating tumor cells(CTCs), circulating tumor cell DNA(ct DNA), and circulating free RNA(cf RNA), have emerged as promising candidates in the burgeoning field of liquid biopsy due to their superior sensitivity and specificity. This review focuses on the latest research on blood-based biomarkers for GC diagnosis and examines the clinical potentials and challenges associated with these emerging biomarkers.

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加巴喷丁治疗尿毒症患者皮肤瘙痒21例

中国新药与临床杂志 2010年第5期29卷 354-357页

作者：伍红英金建生杨德建韩俊愈厦门市仙岳医院内科福建厦门361012

目的观察加巴喷丁治疗尿毒症患者合并皮肤瘙痒症的临床疗效。方法维持性血液透析尿毒症伴皮肤瘙痒患者41例,分为2组。对照组20例,单纯进行血液透析;加巴喷丁组21例,血液透析同时每日睡前口服加巴喷丁0.1 g。1 wk后,比较2组皮肤瘙痒的疗... 详细信息

目的观察加巴喷丁治疗尿毒症患者合并皮肤瘙痒症的临床疗效。方法维持性血液透析尿毒症伴皮肤瘙痒患者41例,分为2组。对照组20例,单纯进行血液透析;加巴喷丁组21例,血液透析同时每日睡前口服加巴喷丁0.1 g。1 wk后,比较2组皮肤瘙痒的疗效。观察2组不良反应发生情况及血红蛋白,血钙、磷,尿素氮、肌酐等指标。结果加巴喷丁组脱落3例,总有效率为89%(16/18),明显高于对照组25%(5/20),2组疗效比较差异非常显著(P<0.01)。2组治疗前后实验室指标均无显著变化,且2组间无明显差异,加巴喷丁组不良反应轻微。结论加巴喷丁治疗尿毒症患者皮肤瘙痒有一定疗效。

关键词：尿毒症瘙痒症皮肤疾病加巴喷丁