检索结果-南通市图书馆

Rare Metals 2023年第1期42卷 296-301页

作者： Yong-Shuang Cui de-bo liu Li-Hua Chai Zi-Yong Chen College of Materials Science and Engineering Beijing University of TechnologyBeijing100124China Beijing Institute of Astronautical Systems Engineering Beijing100076China

Two types of diacetatozirconic acid-yttria molds which were labeled as ZYW mold(diacetatozirconic acidyttria mold with traces of ammoium metatungstate in the slurry) and ZY mold(diacetatozirconic acid-yttria mold without ammonium metatungstate) were prepared by traditional investment *** ZYW and ZY molds were sintered in a carbon-reducing atmosphere and in air,respectively,at 1550℃ for 4 *** between Ti-47Al-2Cr-2Nb(at%) alloys and the molds at 1650℃ for 30 min were *** microstructures of the metalmold interfaces and the presence of inclusions and oxygen contamination in the TiAl bulk alloy were analyzed,and the influences of ammonium metatungstate were *** results indicate that WO_(3)releases O into the TiAl melt,introducing tungsten metal into the alloy *** TiAl alloy ingots cast in the ZY molds had the fewest inclusions and the lowest oxygen contamination.

关键词： TiAl-based alloys Diacetatozirconic acidyttria molds Ammonium metatungstate Interactions

A unified constitutive model for multiphase precipitation and multi-stage creep ageing behavior of Al−Li−S4 alloy

在线全文

学校读者我要写书评

暂无评论

Transactions of Nonferrous Metals Society of China 2021年第5期31卷 1217-1234页

作者： He LI Li-hua ZHAN Ming-hui HUANG Xing ZHAO Chang ZHOU Li-bin HU Zheng-gen HU de-bo liu Light Alloy Research Institute Central South UniversityChangsha 410083China School of Mechanical and Electrical Engineering Central South UniversityChangsha 410083China State Key Laboratory of High-Performance Complex Manufacturing Central South UniversityChangsha 410083China Beijing Institute of Astronautic Systems Engineering Beijing 100076China

A unified constitutive model is presented to predict the recently observed“multi-stage”creep behavior of Al−Li−S4 *** corresponding microstructural variables related to the yield strength and creep deformation of the alloy during the creep ageing process,including dislocations and multiple precipitates,have been characterized in detail by X-ray diffraction(XRD)and transmission electron microscopy(TEM).For the yield strength,the model considers the multiphase strengthening behavior of the alloy based on strengthening mechanisms,which includes shearable T1 precipitate strengthening,non-shearable T1 precipitate strengthening andθ′precipitate *** on creep deformation mechanism,the“multi-stage”creep behavior of the alloy is predicted by introducing the effects of interacting microstructural variables,including the radius of multiple precipitates,dislocation density and solute concentration,into the creep stress−strain *** is concluded that the results calculated by the model are in a good agreement with the experimental data,which validates the proposed model.

关键词： constitutive modelling Al−Li−S4 alloy creep age forming microstructures numerical algorithms

Solution‑Processed Thin Film Transparent Photovoltaics:Present Challenges and Future development

在线全文

学校读者我要写书评

暂无评论

Nano-Micro Letters 2025年第2期17卷 566-600页

作者： Tianle liu Munerah M.S.Almutairi Jie Ma Aisling Stewart Zhaohui Xing Mengxia liu bo Hou Yuljae Cho UM-SJTU Joint Institute Shanghai Jiao Tong UniversityShanghai 200240People’s Republic of China School of Physics and Astronomy Cardiff UniversityCardiff CF243AAWalesUK department of Electrical and Computer Engineering Yale UniversityNew HavenCT 06511USA Energy Sciences Institute Yale UniversityWest HavenCT 06516USA Future Photovoltaics Research Center Global Institute of Future TechnologyShanghai Jiao Tong UniversityShanghai 200240People’s Republic of China

Electrical energy is essential for modern society to sustain economic *** soaring demand for the electrical energy,together with an awareness of the environmental impact of fossil fuels,has been driving a shift towards the utilization of solar ***,traditional solar energy solutions often require extensive spaces for a panel installation,limiting their practicality in a dense urban *** overcome the spatial constraint,researchers have developed transparent photovoltaics(TPV),enabling windows and facades in vehicles and buildings to generate electric *** TPV advancements are focused on improving both transparency and power output to rival commercially available silicon solar *** this review,we first briefly introduce wavelength-and non-wavelengthselective strategies to achieve *** of merit and theoretical limits of TPVs are discussed to comprehensively understand the status of current TPV *** we highlight recent progress in different types of TPVs,with a particular focus on solution-processed thin-film photovoltaics(PVs),including colloidal quantum dot PVs,metal halide perovskite PVs and organic *** applications of TPVs are also reviewed,with emphasis on agrivoltaics,smart windows and ***,current challenges and future opportunities in TPV research are pointed out.

关键词： Transparent semiconductors Solution-processable transparent solar cell Emerging solar cell materials Buildingintegrated photovoltaics

AAV2-Pde6B restores retinal structure and function in the retinal degeneration 10 mouse model of retinitis pigmentosa by promoting phototransduction and inhibiting apoptosis

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第8期20卷 2408-2419页

作者： Ruiqi Qiu Mingzhu Yang Xiuxiu Jin Jingyang liu Weiping Wang Xiaoli Zhang Jinfeng Han bo Lei Henan Eye Hospital Henan Provincial People’s HospitalPeople’s Hospital of Zhengzhou UniversityZhengzhouHenan ProvinceChina Eye Institute Henan Academy of Innovations in Medical ScienceZhengzhouHenan ProvinceChina Branch of National Clinical Research Center for Ocular Disease Henan Provincial People’s HospitalZhengzhouHenan ProvinceChina Academy of Medical Science Zhengzhou UniversityZhengzhouHenan ProvinceChina

Retinitis pigmentosa is a group of inherited diseases that lead to retinal degeneration and photoreceptor cell ***,there is no effective treatment for retinitis pigmentosa caused by Pde6B ***-associated virus(AAV)-mediated gene therapy is a promising strategy for treating retinitis *** aim of this study was to explore the molecular mechanisms by which AAV2-Pde6B rescues retinal *** do this,we injected retinal degeneration 10(rd10)mice subretinally with AAV2-Pde6B and assessed the therapeutic effects on retinal function and structure using dark-and light-adapted electroretinogram,optical coherence tomography,and ***-independent acquisition-mass spectrometry-based proteomic analysis was conducted to investigate protein expression levels and pathway enrichment,and the results from this analysis were verified by real-time polymerase chain reaction and western ***2-Pde6B injection significantly upregulated Pde6βexpression,preserved electroretinogram responses,and preserved outer nuclear layer thickness in rd10 *** expressed proteins between wild-type and rd10 mice were closely related to visual perception,and treating rd10 mice with AAV2-Pde6B restored differentially expressed protein expression to levels similar to those seen in wild-type *** Encyclopedia of Genes and Genome analysis showed that the differentially expressed proteins whose expression was most significantly altered by AAV2-Pde6B injection were enriched in phototransduction ***,the phototransductionrelated proteins Pde6α,Rom1,Rho,Aldh1a1,and Rbp1 exhibited opposite expression patterns in rd10 mice with or without AAV2-Pde6B ***,Bax/Bcl-2,p-ERK/ERK,and p-c-Fos/c-Fos expression levels decreased in rd10 mice following AAV2-Pde6B *** data suggest that AAV2-Pde6B-mediated gene therapy promotes phototransduction and inhibits apoptosis by inhibiting the ERK signaling pathway and upr

关键词： apoptosis AAV2-Pde6B ERK1/2 gene therapy phototransduction proteomics rd10 retinitis pigmentosa

Association between autoimmune gastritis and gastric polyps:Clinical characteristics and risk factors

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Oncology 2025年第1期17卷 73-87页

作者： Jing-Zheng Jin Xiao Liang Shu-Peng liu Rui-Lan Wang Qing-Wei Zhang Yu-Feng Shen Xiao-bo Li Division of Gastroenterology and Hepatology Renji HospitalShanghai Jiao Tong University School of MedicineShanghai 200127China Division of Gastroenterology and Hepatology Shanghai Institute of Digestive DiseasesShanghai 200001China Division of Gastroenterology and Hepatology Renji Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai 200127China Division of Gastroenterology and Hepatology Sichuan Armed Police Corps HospitalLeshan 610041Sichuan ProvinceChina Division of Gastroenterology and Hepatology NHC Key Laboratory of Digestive DiseasesRenji HospitalShanghai Jiao Tong University School of MedicineShanghai 200127China department of Gastroenterology Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai Institute of Digestive DiseasesShanghai 200127China

BACKGROUND The relationship between autoimmune gastritis(AIG)and gastric polyps(GPs)is not well *** To explore the clinical characteristics and risk factors of AIG with GPs in *** This double center retrospective study included 530 patients diagnosed with AIG from July 2019 to July *** collected clinical,biochemical,serological,and demographic data were of each *** regression analyses,both multivariate and univariate,were conducted to pinpoint independent risk factors for GPs in patients with AIG *** operating characteristic curves were utilized to establish the optimal cutoff values,sensitivity,and specificity of these risk factors for predicting GPs in patients with *** Patients with GPs had a higher median age than those without GPs[61(52.25-69)years vs 58(47-66)years,P=0.006].The gastrin-17 levels were significantly elevated in patients with GPs compared with those without GPs[91.9(34.2-138.9)pmol/mL vs 60.9(12.6-98.4)pmol/mL,Pbody(PCA)antibody was higher in these patients than in those without GPs(88.6%vs 73.6%,Pdentified as a protective *** PCA positivity and enterochromaffin like cells hyperplasia are significant risk factor for the development of GPs in patients with *** gastrin-17 levels may also play a role in this *** findings suggest potential targets for further research and therapeutic intervention in managing GPs in patients with AIG.

关键词： Autoimmune gastritis Gastric polyps Neuroendocrine tumor Risk factors Nomogram

Experimental study on decoy oligodeoxynucleotides targeting activated STAT3 to suppress bladder cancer cell growth

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Experimental study on decoy oligodeoxynucleotides targeting ...

Comprehensive bibliometric analysis of pharmacotherapy for bipolar disorders:Present trends and future directions

第十三届全国泌尿外科学术会议暨第八届全球华人泌尿外科学术会议

作者： YAO Lin-fang,YE Zhang-qun,CHEN Zhi-qiang, KONG de-bo, liu Guan-lin, YANG Wei-min.. department of Urology,Tongji Hospital,Tongji Medical College of Huazhong University of Science and Technology,Wuhan 430030,China

Objective To investigate the effects of STAT3 decoy oligodeoxynucleotides on the proliferation and apoptosis of bladder cancer T24 cell and explore the mechanism. Methods STAT3 decoy oligodeoxynucleotides were transfected into bladder cancer T24 cells. The cell vitality and proliferation were detected by Trypan Blue staining rejection, cell counting and MTT assay. Fluorescence dyestuff

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

World Journal of Psychiatry 2025年第1期15卷 153-167页

作者： bo-Fan Chen Li liu Fang-Zhen Lin Hai-Min Zeng Hai-Qiang Huang Chun-Fang Zhang Cong-Cong liu Xiang Chen Jie Peng Yun-Fa Wang Zhi-Lin Wang Bin Chen de-Le liu Yun liu Zheng-Zheng Li Xin-Xing Zeng The Second Affiliated Hospital Jiangxi Medical CollegeNanchang UniversityNanchang 330006Jiangxi ProvinceChina The Second Clinical Medical College Jiangxi Medical CollegeNanchang UniversityNanchang 330006Jiangxi ProvinceChina department of Rehabilitation Medicine The Second Affiliated HospitalJiangxi Medical CollegeNanchang UniversityNanchang 330006Jiangxi ProvinceChina Jiangxi Provincial People’s Hospital The First Affiliated Hospital of Nanchang Medical CollegeNanchang 330006Jiangxi ProvinceChina department of Psychiatry Jiangxi Mental HospitalHospital of Nanchang UniversityNanchang UniversityNanchang 330029Jiangxi ProvinceChina

BACKGROUND Bipolar disorder(BD)is a severe mental illness characterized by significant mood *** drug treatment modalities are crucial for managing *** To analyze the current status and future trends of global research on BD drug treatment over the last *** The Web of Science Core Collection database spanning from 2015 to 2024 was utilized to retrieve literature related to BD drug treatment.A total of 2624 articles were *** visualization and analysis were conducted using CiteSpace,VOSviewer,Pajek,Scimago Graphica,and R-studio bibliometrix to identify RESULTS The United States,China,and the United Kingdom have made the most significant contributions to research on BD drug treatment and formed notable research collaboration *** University of Pittsburgh,Massachusetts General Hospital,and the University of Michigan have been identified as the major research institutions in this *** Journal of Affective Disorders is the most influential journal.A keyword analysis revealed research hotspots related to clinical symptoms,drug efficacy,and genetic mechanisms.A citation analysis identified the management guidelines published by Yatham et al in 2018 as the most cited *** This study provides a detailed overview of the field of BD drug treatment,highlighting key contributors,research hotspots,and future *** study findings can be employed as a reference for future research and policymaking,which may enable further development and optimization of BD pharmacotherapy.

关键词： Bipolar disorder Drug treatment Bibliometric analysis Visualization Mental disorder

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

柞丝绸等离子体染色前处理

丝绸 2004年第6期41卷 30-32页

作者：谢洪德刘波王红卫苏州大学材料工程学院江苏苏州215021

应用低温等离子体对柞丝织物进行染色前处理。研究表明,处理后可去除织物表面杂质,纤维表面性能发生变化,提高了柞丝织物吸湿性能和染色性能,并且降低能耗、缩短工艺时间,可取得比常规前处理工艺更为显著的效果。

关键词：柞丝绸等离子体染色前处理织物性能

在线全文

学校读者我要写书评

暂无评论

某基坑工程施工监测方法与分析

施工技术 2003年第8期32卷 39-40页

作者：张德波刘良贵安岚广州市市政工程设计研究院广东广州510060

某泵站工程分为吸水井区和泵房区，高18m，基坑长113.20m,宽40.00～76.00m，吸水井区深5.80m，泵房区深10.00m，基坑支护采用地下连续墙永久结构，墙底进入泥岩2.00m以上，墙厚800mm。吸水井区压顶梁处采用钢筋混凝土支撑，泵房区采用... 详细信息

某泵站工程分为吸水井区和泵房区，高18m，基坑长113.20m,宽40.00～76.00m，吸水井区深5.80m，泵房区深10.00m，基坑支护采用地下连续墙永久结构，墙底进入泥岩2.00m以上，墙厚800mm。吸水井区压顶梁处采用钢筋混凝土支撑，泵房区采用双排拉锚点支撑，第1排锚杆距基坑顶2.20m，间距2.00m；第2排锚杆距基坑顶4.70m，间距1.50m。

关键词：基坑工程工程施工监测泵站支护地下连续墙

Human-induced pluripotent stem cell-derived neural stem cell exosomes improve blood-brain barrier function after intracerebral hemorrhage by activating astrocytes via PI3K/AKT/MCP-1 axis

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第2期20卷 518-532页

作者： Conglin Wang Fangyuan Cheng Zhaoli Han bo Yan Pan Liao Zhenyu Yin Xintong Ge Dai Li Rongrong Zhong Qiang liu Fanglian Chen Ping Lei department of Geriatrics Tianjin Medical University General HospitalTianjinChina School of Medicine Nankai UniversityTianjinChina Tianjin Neurological Institute TianjinChina

Cerebral edema caused by blood-brain barrier injury after intracerebral hemorrhage is an important factor leading to poor ***-induced pluripotent stem cell-derived neural stem cell exosomes(hiPSC-NSC-Exos)have shown potential for brain injury repair in central nervous system *** this study,we explored the impact of hiPSC-NSC-Exos on blood-brain barrier preservation and the underlying *** results indicated that intranasal delivery of hiPSC-NSC-Exos mitigated neurological deficits,enhanced blood-brain barrier integrity,and reduced leukocyte infiltration in a mouse model of intracerebral ***,hiPSC-NSC-Exos decreased immune cell infiltration,activated astrocytes,and decreased the secretion of inflammatory cytokines like monocyte chemoattractant protein-1,macrophage inflammatory protein-1α,and tumor necrosis factor-αpost-intracerebral hemorrhage,thereby improving the inflammatory *** sequencing indicated that hiPSC-NSC-Exo activated the PI3K/AKT signaling pathway in astrocytes and decreased monocyte chemoattractant protein-1 secretion,thereby improving blood-brain barrier *** with the PI3K/AKT inhibitor LY294002 or the monocyte chemoattractant protein-1 neutralizing agent C1142 abolished these *** summary,our findings suggest that hiPSC-NSC-Exos maintains blood-brain barrier integrity,in part by downregulating monocyte chemoattractant protein-1 secretion through activation of the PI3K/AKT signaling pathway in astrocytes.

关键词： AKT astrocyte blood-brain barrier cerebral edema exosomes human-induced pluripotent stem cells intracerebral hemorrhage neural stem cells neuroinflammation PI3K