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The optimization of phenolic compounds extraction from cactus pear(Opuntia ficus-indica) skin in a reflux system using response surface methodology

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Asian Pacific Journal of Tropical Biomedicine 2013年第6期3卷 436-442页

作者： Aguirre Joya Jorge de la garza toledo heliodoro Zugasti Cruz Alejandro Belmares Cerda Ruth Aguilar Cristóbal No Food Research department School of ChemistryUniversidad Autonóma de Coahuila Basic Science department Universidad Autonóma Agraria Antonio Narro

Objective:To extract,quantify,and evaluate the phenolic content in Opuntia ficus-indica skin for their antioxidant capacity with three different methods(ABTS,DPPH,and lipid oxidation)and to optimize the extraction conditions[time,temperature and ethanol concentration)in a reflux ***:The extraction process was done using a reflux system.A San CristobalⅡexperimental design with three variables and three levels was *** variables evaluated were time of extraction(h),concentration of ethanol(%,v/v)and temperature(°C).The extraction process was optimized using a response surface ***:It was observed that at higher temperature more phenolic compounds were extracted,but the antioxidant capacity was *** optimum conditions for phenolic compounds extraction and antioxidant capacity mixing the three methods were as Follows:45%of ethanol,80℃and 2 hours of *** obtained in our results are little higher that other previously ***:It can he concluded the by-products of Opuntia ficus-indica represent a good source of natural antioxidants with possible applications in food,cosmetics or drugs industries.

关键词： Opuntia ficus-indica Reflux Phenolics Antioxidants Prickly pear Response surface methodology

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Polyphenolic content, in vitro antioxidant activity and chemical composition of extract from Nephelium lappaceum L.(Mexican rambutan) husk

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Asian Pacific Journal of Tropical Medicine 2017年第12期10卷 1201-1205页

作者： Cristian Hernández Juan Ascacio-Valdés heliodoro de la garza Jorge Wong-Paz Cristóbal Noé Aguilar Guillermo Cristian Martínez- ávila Cecilia Castro-López Antonio Aguilera-Carbó department of Animal Nutrition Universidad Autónoma Agraria Antonio NarroCol. BuenavistaCalzada Antonio Narro No. 1923Saltillo25315CoahuilaMexico Food Research department School of ChemistryUniversidad Autónoma de CoahuilaBlvd. Venustiano CarranzaCol. RepúblicaSaltillo25280CoahuilaMexico Chemistry and Biochemistry laboratory Faculty of AgronomyUniversidad Autónoma de Nuevo LeónFrancisco I. Madero S/NHacienda el Canada66050General EscobedoNLMexico

Objective: To determinate the recovery of total polyphenolic compounds content,in vitro antioxidant activity and HPLC/ESI/MS characterization of extract from Nephelium lappaceum L.(Mexican rambutan).Methods: The rambutan husk extract was obtained by aqueous extraction and a polyphenolic fraction was recovered using Amberlite XAD-16. The total polyphenolic compounds content was determined by the Folin Ciocalteu and butanol-HCI *** vitro antioxidant activity was performed using ABTS and ferric reducing antioxidant power ***: Mexican rambutan husk showed a total polyphenolic content of 582 mg/g and an evident antioxidant activity by ABTS and ferric reducing antioxidant power *** HPLC/ESI/MS assay allowed the identification of 13 compounds, most of which belong to ellagitannins. Geraniin, corilagin and ellagic acid were present in the sample;the mineral composition was also ***: Rambutan husk cultivated in Mexico is a promising source for the recovery of added value bioactive compounds with antioxidant activity, which have potential applications as bioactive antioxidant agents for the treatment of diseases.

关键词： Mexican rambutan Polyphenolic compounds Ellagitannins HPLC/ESI/MS

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Low-Risk Papillary Thyroid Carcinoma Recurring as a Single Brain Metastasis: A Case Report and Literature Review

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International Journal of Otolaryngology and Head & Neck Surgery 2024年第6期13卷 468-478页

作者： Carlos Hernández Brito Luis Ángel Amezcua toledo Itzel Reyes de la garza Luis Eduardo Méndez Turrubiates Brenda Paola Sáenz Dávila Arsenio Torres delgado Yedid del Carmen Domínguez Suárez Pedro Arredondo Ruiz Rosa Isela Luna Ceballos Surgical Oncology department Onkolid Oncology Center Veracruz Mexico Radiology department Onkolid Oncology Center Veracruz Mexico Anatomical Pathology department Spanish Hospital Veracruz Mexico Radiation Oncology department Onkolid Oncology Center Veracruz Mexico Clinical Oncology department Onkolid Oncology Center Veracruz Mexico General-laparoscopic Surgery Torres Medical-Surgical Corporation Veracruz Mexico Endocrinology department Society of Metabolism and Heart SOMECO Veracruz Mexico

Background: Brain metastases from papillary thyroid carcinoma are infrequent occurring in 0.15% to 1.3% of patients, and they are generally accompanied by synchronous metastases in other sites and in isolation are even less frequent;the information about their management is limited and it has been based mainly on retrospective studies, experiences, case reports, and management guidelines of brain metastasis of other cancers. Aim: We report this case with the objective of describing how unpredictable the behavior of thyroid cancer can be despite being classified as low risk of recurrence. Case Presentation: A female patient with a diagnosis of papillary thyroid carcinoma classified as low risk who after more than a year of surveillance and without alterations in laboratory and imaging studies, developed a single brain metastasis susceptible to treatment with radioactive iodine (RAI) therapy. Conclusion: This case emphasizes the importance of a close follow-up of patients and not to minimize any symptom, no matter how simple it may seem, since cancer has no rules in its evolution.

关键词： Thyroid Cancer Papillary Thyroid Carcinoma Brain Metastasis

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